Reactome | OPRL1 [plasma membrane]

OPRL1 [plasma membrane]

Stable Identifier

R-HSA-374731

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Nociceptin receptor, OPRX_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P41146 OPRL1

Gene Names

OPRL1, OOR, ORL1

Chain

chain:1-370

Reference Genes

BioGPS Gene:4987 OPRL1

COSMIC (genes):OPRL1 OPRL1

CTD Gene:4987 OPRL1

dbSNP Gene:4987 OPRL1

ENSEMBL:ENSG00000125510 OPRL1

ENSEMBL_homo_sapiens_GENE:ENSG00000125510.18 OPRL1

HGNC:8155 OPRL1

KEGG Gene (Homo sapiens):4987 OPRL1

Monarch:4987 OPRL1

NCBI Gene:4987 OPRL1

OMIM:602548 OPRL1

UCSC:P41146 OPRL1

Reference Transcript

Other Identifiers

11744636_a_at

11744637_a_at

16916223

206563_PM_s_at

206563_s_at

206564_PM_at

206564_at

34558_at

3893948

3893949

3893950

3893953

3893957

3893958

3893959

3893964

3893967

3893968

3893969

3893970

4987

67115_at

8064261

A_14_P135019

A_23_P345564

A_33_P3359647

GE80259

GO:0001626

GO:0003013

GO:0003014

GO:0004930

GO:0004985

GO:0005515

GO:0005886

GO:0007165

GO:0007186

GO:0007193

GO:0007200

GO:0007218

GO:0007600

GO:0007610

GO:0016020

GO:0019233

GO:0019722

GO:0022414

GO:0023052

GO:0031410

GO:0032355

GO:0035810

GO:0038003

GO:0042755

GO:0042923

GO:0043005

GO:0043226

GO:0043951

GO:0044849

GO:0045776

GO:0050877

GO:0060089

GO:0106072

GO:1904059

GO:1990708

HMNXSV003026734

ILMN_1713758

ILMN_2400922

ILMN_2400926

PH_hs_0000363

TC20000534.hg

TC20001364.hg

U30185_at

g13022242_3p_a_at

g13022242_3p_s_at

g4505512_3p_at

g4505512_3p_x_at

p33875

Participates

as an input of

Nociceptin receptor binds to nociceptin (Homo sapiens)

as a component of

Nociceptin receptor:Nociceptin [plasma membrane] (Homo sapiens)

Inferred To

Oprl1 [plasma membrane] (Mus musculus)

Oprl1 [plasma membrane] (Rattus norvegicus)

OPRL1 [plasma membrane] (Bos taurus)

OPRL1 [plasma membrane] (Gallus gallus)

OPRL1 [plasma membrane] (Sus scrofa)

oprl1 [plasma membrane] (Xenopus tropicalis)

Cross References

RefSeq

NP_872588.1, XP_016883344.1, NP_001305784.1, XP_016883343.1, NP_001186948.1, NP_001305783.1, NP_000904.1, NP_001305782.1

ZINC - World Drugs

OPRX_HUMAN

Guide to Pharmacology - Targets

320

OpenTargets

ENSG00000125510

ZINC - Substances

OPRX_HUMAN

ZINC - Biogenic

OPRX_HUMAN

ZINC target

P41146

PRO

P41146

PDB

5DHH, 5DHG, 4EA3, 8F7X

ZINC - Investigational

OPRX_HUMAN

ZINC - Metabolites

OPRX_HUMAN

HPA

ENSG00000125510-OPRL1

GeneCards

P41146

Ensembl

ENST00000355631, ENST00000349451, ENSG00000125510, ENSP00000336843, ENSP00000347848, ENST00000336866, ENSP00000336764

Pharos - Targets

P41146

ZINC - Predictions - Purchasable

OPRX_HUMAN

HMDB Protein

HMDBP13990

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q6ZMG9 CERS6	1	CERS6 [endoplasmic reticulum membrane] (R-HSA-428145)	0.508	2