Reactome | GNA13 [plasma membrane]

GNA13 [plasma membrane]

Stable Identifier

R-GGA-167451

Type

Protein [EntityWithAccessionedSequence]

Species

Gallus gallus

Compartment

plasma membrane

Synonyms

A0A1D5PQE8

Locations in the PathwayBrowser

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Hemostasis (Gallus gallus)

- Platelet activation, signaling and aggregation (Gallus gallus)
  - Signal amplification (Gallus gallus)
    - Thromboxane signalling through TP receptor (Gallus gallus)
      - Activated TP receptor binds G-protein G13 (Gallus gallus)
        
        Heterotrimeric G-protein G13 (inactive) [plasma membrane] (Gallus gallus)
        
        G-protein alpha (13):GDP [plasma membrane] (Gallus gallus)
        
        GNA13 [plasma membrane] (Gallus gallus)
        
        TP receptor:Thromboxane A2:G-protein G13 (inactive) [plasma membrane] (Gallus gallus)
        
        Heterotrimeric G-protein G13 (inactive) [plasma membrane] (Gallus gallus)
        
        G-protein alpha (13):GDP [plasma membrane] (Gallus gallus)
        
        GNA13 [plasma membrane] (Gallus gallus)
      - Dissociation of the TP:G13 complex (Gallus gallus)
        
        G-protein alpha (13):GTP [plasma membrane] (Gallus gallus)
        
        GNA13 [plasma membrane] (Gallus gallus)
        
        TP receptor:Thromboxane A2:G-protein G13 (active) [plasma membrane] (Gallus gallus)
        
        Heterotrimeric G-protein G13 (active) [plasma membrane] (Gallus gallus)
        
        G-protein alpha (13):GTP [plasma membrane] (Gallus gallus)
        
        GNA13 [plasma membrane] (Gallus gallus)
      - G13 activation by TP receptor (Gallus gallus)
        
        TP receptor:Thromboxane A2:G-protein G13 (active) [plasma membrane] (Gallus gallus)
        
        Heterotrimeric G-protein G13 (active) [plasma membrane] (Gallus gallus)
        
        G-protein alpha (13):GTP [plasma membrane] (Gallus gallus)
        
        GNA13 [plasma membrane] (Gallus gallus)
        
        TP receptor:Thromboxane A2:G-protein G13 (inactive) [plasma membrane] (Gallus gallus)
        
        Heterotrimeric G-protein G13 (inactive) [plasma membrane] (Gallus gallus)
        
        G-protein alpha (13):GDP [plasma membrane] (Gallus gallus)
        
        GNA13 [plasma membrane] (Gallus gallus)
  - Thrombin signalling through proteinase activated receptors (PARs) (Gallus gallus)
    - Thrombin-activated PARs activate G12/13 (Gallus gallus)
      - Thrombin activated PAR:G12/13 (active) [plasma membrane] (Gallus gallus)
        
        G-protein G12/G13 (active) [plasma membrane] (Gallus gallus)
        
        Heterotrimeric G-protein G13 (active) [plasma membrane] (Gallus gallus)
        
        G-protein alpha (13):GTP [plasma membrane] (Gallus gallus)
        
        GNA13 [plasma membrane] (Gallus gallus)
      - Thrombin activated PAR:G12/13 (inactive) [plasma membrane] (Gallus gallus)
        
        G-protein G12/G13 (inactive) [plasma membrane] (Gallus gallus)
        
        Heterotrimeric G-protein G13 (inactive) [plasma membrane] (Gallus gallus)
        
        G-protein alpha (13):GDP [plasma membrane] (Gallus gallus)
        
        GNA13 [plasma membrane] (Gallus gallus)
    - Thrombin-activated PARs:G12/13 (active) dissociate (Gallus gallus)
      - G-protein alpha (12/13):GTP [plasma membrane] (Gallus gallus)
        
        G-protein alpha (13):GTP [plasma membrane] (Gallus gallus)
        
        GNA13 [plasma membrane] (Gallus gallus)
      - Thrombin activated PAR:G12/13 (active) [plasma membrane] (Gallus gallus)
        
        G-protein G12/G13 (active) [plasma membrane] (Gallus gallus)
        
        Heterotrimeric G-protein G13 (active) [plasma membrane] (Gallus gallus)
        
        G-protein alpha (13):GTP [plasma membrane] (Gallus gallus)
        
        GNA13 [plasma membrane] (Gallus gallus)

External Reference Information

External Reference

UniProt:A0A1D5PQE8

Reference Genes

BioGPS Gene:417434

ENSEMBL:ENSGALG00010029383.1

KEGG:gga:417434

Monarch:417434

NCBI Gene:417434

UCSC:A0A1D5PQE8

Reference Transcript

Other Identifiers

417434

GO:0000166

GO:0001525

GO:0001569

GO:0001664

GO:0003924

GO:0003925

GO:0005525

GO:0005634

GO:0005737

GO:0005829

GO:0005834

GO:0005886

GO:0007165

GO:0007186

GO:0007188

GO:0007189

GO:0007266

GO:0008217

GO:0008360

GO:0010762

GO:0016020

GO:0016787

GO:0019001

GO:0030154

GO:0030168

GO:0031526

GO:0031683

GO:0031752

GO:0035556

GO:0046872

GO:0098772

GO:0098794

GO:0150052

GO:0160221

GT_A_87_P014558

GT_A_87_P151248

Gga.10622.1.S1_at

Gga.16821.1.S1_at

Gga.17577.1.S1_at

Participates

as a candidate of

CDC42 GEFs [cytosol] (Gallus gallus)

as a member of

RAC1 GEFs [cytosol] (Gallus gallus)

as a component of

Inferred From

GNA13 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

XP_040542413.1, XP_415686.1

ENSEMBL

ENSGALG00010029383, ENSGALT00010071068, ENSGALP00010043759

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