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About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
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Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
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How do I search ?
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KLB [plasma membrane]
Stable Identifier
R-GGA-1307932
Type
Protein [EntityWithAccessionedSequence]
Species
Gallus gallus
Compartment
plasma membrane
Synonyms
KLB, A0A8V0Z2L0
Locations in the PathwayBrowser
Expand all
Signal Transduction (Gallus gallus)
Intracellular signaling by second messengers (Gallus gallus)
PIP3 activates AKT signaling (Gallus gallus)
Negative regulation of the PI3K/AKT network (Gallus gallus)
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling (Gallus gallus)
PI3K phosphorylates PIP2 to PIP3 (Gallus gallus)
Activator:PI3K [plasma membrane] (Gallus gallus)
Activated FGFR4:p-FRS2:GRB2:GAB1:PI3K [plasma membrane] (Gallus gallus)
Activated FGFR4:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Gallus gallus)
Activated FGFR4:p-FRS2 [plasma membrane] (Gallus gallus)
Activated FGFR4 [plasma membrane] (Gallus gallus)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Gallus gallus)
KLB [plasma membrane] (Gallus gallus)
PI3K phosphorylates PIP2 to PIP3 (Gallus gallus)
Activator:PI3K [plasma membrane] (Gallus gallus)
Activated FGFR4:p-FRS2:GRB2:GAB1:PI3K [plasma membrane] (Gallus gallus)
Activated FGFR4:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Gallus gallus)
Activated FGFR4:p-FRS2 [plasma membrane] (Gallus gallus)
Activated FGFR4 [plasma membrane] (Gallus gallus)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Gallus gallus)
KLB [plasma membrane] (Gallus gallus)
MAPK family signaling cascades (Gallus gallus)
MAPK1/MAPK3 signaling (Gallus gallus)
RAF/MAP kinase cascade (Gallus gallus)
RAS GEFs promote RAS nucleotide exchange (Gallus gallus)
RAS GEFs [plasma membrane] (Gallus gallus)
Activated FGFR4:p-FRS2:GRB2:SOS1 [plasma membrane] (Gallus gallus)
Activated FGFR4:p-FRS [plasma membrane] (Gallus gallus)
Activated FGFR4:p-FRS2 [plasma membrane] (Gallus gallus)
Activated FGFR4 [plasma membrane] (Gallus gallus)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Gallus gallus)
KLB [plasma membrane] (Gallus gallus)
Activated FGFR4:p-FRS3 [plasma membrane] (Gallus gallus)
Activated FGFR4 [plasma membrane] (Gallus gallus)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Gallus gallus)
KLB [plasma membrane] (Gallus gallus)
Activated FGFR4:pY-SHC1:GRB2:SOS1 [plasma membrane] (Gallus gallus)
Activated FGFR4:pY-SHC1 [plasma membrane] (Gallus gallus)
Activated FGFR4 [plasma membrane] (Gallus gallus)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Gallus gallus)
KLB [plasma membrane] (Gallus gallus)
Signaling by Receptor Tyrosine Kinases (Gallus gallus)
Signaling by FGFR (Gallus gallus)
Signaling by FGFR4 (Gallus gallus)
Downstream signaling of activated FGFR4 (Gallus gallus)
FRS-mediated FGFR4 signaling (Gallus gallus)
Activated FGFR4 binds FRS2 (Gallus gallus)
Activated FGFR4 [plasma membrane] (Gallus gallus)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Gallus gallus)
KLB [plasma membrane] (Gallus gallus)
Activated FGFR4:FRS2 [plasma membrane] (Gallus gallus)
Activated FGFR4 [plasma membrane] (Gallus gallus)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Gallus gallus)
KLB [plasma membrane] (Gallus gallus)
Activated FGFR4 binds FRS3 (Gallus gallus)
Activated FGFR4 [plasma membrane] (Gallus gallus)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Gallus gallus)
KLB [plasma membrane] (Gallus gallus)
Activated FGFR4:FRS3 [plasma membrane] (Gallus gallus)
Activated FGFR4 [plasma membrane] (Gallus gallus)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Gallus gallus)
KLB [plasma membrane] (Gallus gallus)
Activated FGFR4 phosphorylates FRS2 (Gallus gallus)
Activated FGFR4:FRS2 [plasma membrane] (Gallus gallus)
Activated FGFR4 [plasma membrane] (Gallus gallus)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Gallus gallus)
KLB [plasma membrane] (Gallus gallus)
Activated FGFR4:p-8T-FRS2 [plasma membrane] (Gallus gallus)
Activated FGFR4 [plasma membrane] (Gallus gallus)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Gallus gallus)
KLB [plasma membrane] (Gallus gallus)
Activated FGFR4:p-FRS2 [plasma membrane] (Gallus gallus)
Activated FGFR4 [plasma membrane] (Gallus gallus)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Gallus gallus)
KLB [plasma membrane] (Gallus gallus)
Activated FGFR4 phosphorylates FRS3 (Gallus gallus)
Activated FGFR4:FRS3 [plasma membrane] (Gallus gallus)
Activated FGFR4 [plasma membrane] (Gallus gallus)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Gallus gallus)
KLB [plasma membrane] (Gallus gallus)
Activated FGFR4:p-FRS3 [plasma membrane] (Gallus gallus)
Activated FGFR4 [plasma membrane] (Gallus gallus)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Gallus gallus)
KLB [plasma membrane] (Gallus gallus)
Activated FGFR4 phosphorylates PPTN11 (Gallus gallus)
Activated FGFR4:p-FRS:PTPN11 [plasma membrane] (Gallus gallus)
Activated FGFR4:p-FRS [plasma membrane] (Gallus gallus)
Activated FGFR4:p-FRS2 [plasma membrane] (Gallus gallus)
Activated FGFR4 [plasma membrane] (Gallus gallus)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Gallus gallus)
KLB [plasma membrane] (Gallus gallus)
Activated FGFR4:p-FRS3 [plasma membrane] (Gallus gallus)
Activated FGFR4 [plasma membrane] (Gallus gallus)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Gallus gallus)
KLB [plasma membrane] (Gallus gallus)
Activated FGFR4:p-FRS:p-PTPN11 [plasma membrane] (Gallus gallus)
Activated FGFR4:p-FRS [plasma membrane] (Gallus gallus)
Activated FGFR4:p-FRS2 [plasma membrane] (Gallus gallus)
Activated FGFR4 [plasma membrane] (Gallus gallus)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Gallus gallus)
KLB [plasma membrane] (Gallus gallus)
Activated FGFR4:p-FRS3 [plasma membrane] (Gallus gallus)
Activated FGFR4 [plasma membrane] (Gallus gallus)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Gallus gallus)
KLB [plasma membrane] (Gallus gallus)
Activated FGFR4:p-FRS bind to PPTN11 (Gallus gallus)
Activated FGFR4:p-FRS [plasma membrane] (Gallus gallus)
Activated FGFR4:p-FRS2 [plasma membrane] (Gallus gallus)
Activated FGFR4 [plasma membrane] (Gallus gallus)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Gallus gallus)
KLB [plasma membrane] (Gallus gallus)
Activated FGFR4:p-FRS3 [plasma membrane] (Gallus gallus)
Activated FGFR4 [plasma membrane] (Gallus gallus)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Gallus gallus)
KLB [plasma membrane] (Gallus gallus)
Activated FGFR4:p-FRS:PTPN11 [plasma membrane] (Gallus gallus)
Activated FGFR4:p-FRS [plasma membrane] (Gallus gallus)
Activated FGFR4:p-FRS2 [plasma membrane] (Gallus gallus)
Activated FGFR4 [plasma membrane] (Gallus gallus)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Gallus gallus)
KLB [plasma membrane] (Gallus gallus)
Activated FGFR4:p-FRS3 [plasma membrane] (Gallus gallus)
Activated FGFR4 [plasma membrane] (Gallus gallus)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Gallus gallus)
KLB [plasma membrane] (Gallus gallus)
Activated FGFR4:p-FRS binds GRB2:SOS1 (Gallus gallus)
Activated FGFR4:p-FRS [plasma membrane] (Gallus gallus)
Activated FGFR4:p-FRS2 [plasma membrane] (Gallus gallus)
Activated FGFR4 [plasma membrane] (Gallus gallus)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Gallus gallus)
KLB [plasma membrane] (Gallus gallus)
Activated FGFR4:p-FRS3 [plasma membrane] (Gallus gallus)
Activated FGFR4 [plasma membrane] (Gallus gallus)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Gallus gallus)
KLB [plasma membrane] (Gallus gallus)
Activated FGFR4:p-FRS2:GRB2:SOS1 [plasma membrane] (Gallus gallus)
Activated FGFR4:p-FRS [plasma membrane] (Gallus gallus)
Activated FGFR4:p-FRS2 [plasma membrane] (Gallus gallus)
Activated FGFR4 [plasma membrane] (Gallus gallus)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Gallus gallus)
KLB [plasma membrane] (Gallus gallus)
Activated FGFR4:p-FRS3 [plasma membrane] (Gallus gallus)
Activated FGFR4 [plasma membrane] (Gallus gallus)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Gallus gallus)
KLB [plasma membrane] (Gallus gallus)
Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Gallus gallus)
Activated FGFR4:p-FRS2:GRB2:SOS1 [plasma membrane] (Gallus gallus)
Activated FGFR4:p-FRS [plasma membrane] (Gallus gallus)
Activated FGFR4:p-FRS2 [plasma membrane] (Gallus gallus)
Activated FGFR4 [plasma membrane] (Gallus gallus)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Gallus gallus)
KLB [plasma membrane] (Gallus gallus)
Activated FGFR4:p-FRS3 [plasma membrane] (Gallus gallus)
Activated FGFR4 [plasma membrane] (Gallus gallus)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Gallus gallus)
KLB [plasma membrane] (Gallus gallus)
Activated FGFR4:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Gallus gallus)
Activated FGFR4:p-FRS:p-PTPN11 [plasma membrane] (Gallus gallus)
Activated FGFR4:p-FRS [plasma membrane] (Gallus gallus)
Activated FGFR4:p-FRS2 [plasma membrane] (Gallus gallus)
Activated FGFR4 [plasma membrane] (Gallus gallus)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Gallus gallus)
KLB [plasma membrane] (Gallus gallus)
Activated FGFR4:p-FRS3 [plasma membrane] (Gallus gallus)
Activated FGFR4 [plasma membrane] (Gallus gallus)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Gallus gallus)
KLB [plasma membrane] (Gallus gallus)
PI-3K cascade:FGFR4 (Gallus gallus)
Activated FGFR4:p-FRS2 binds GRB2:GAB1:PIK3R1 (Gallus gallus)
Activated FGFR4:p-FRS2 [plasma membrane] (Gallus gallus)
Activated FGFR4 [plasma membrane] (Gallus gallus)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Gallus gallus)
KLB [plasma membrane] (Gallus gallus)
Activated FGFR4:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Gallus gallus)
Activated FGFR4:p-FRS2 [plasma membrane] (Gallus gallus)
Activated FGFR4 [plasma membrane] (Gallus gallus)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Gallus gallus)
KLB [plasma membrane] (Gallus gallus)
Activated FGFR4:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA (Gallus gallus)
Activated FGFR4:p-FRS2:GRB2:GAB1:PI3K [plasma membrane] (Gallus gallus)
Activated FGFR4:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Gallus gallus)
Activated FGFR4:p-FRS2 [plasma membrane] (Gallus gallus)
Activated FGFR4 [plasma membrane] (Gallus gallus)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Gallus gallus)
KLB [plasma membrane] (Gallus gallus)
Activated FGFR4:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Gallus gallus)
Activated FGFR4:p-FRS2 [plasma membrane] (Gallus gallus)
Activated FGFR4 [plasma membrane] (Gallus gallus)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Gallus gallus)
KLB [plasma membrane] (Gallus gallus)
Activated FGFR4:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 (Gallus gallus)
Activated FGFR4:p-FRS2:p-PTPN11 [plasma membrane] (Gallus gallus)
Activated FGFR4:p-FRS2 [plasma membrane] (Gallus gallus)
Activated FGFR4 [plasma membrane] (Gallus gallus)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Gallus gallus)
KLB [plasma membrane] (Gallus gallus)
Activated FGFR4:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] (Gallus gallus)
Activated FGFR4:p-FRS2:p-PTPN11 [plasma membrane] (Gallus gallus)
Activated FGFR4:p-FRS2 [plasma membrane] (Gallus gallus)
Activated FGFR4 [plasma membrane] (Gallus gallus)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Gallus gallus)
KLB [plasma membrane] (Gallus gallus)
Activated FGFR4:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1binds PIK3CA (Gallus gallus)
Activated FGFR4:p-FRS2:p-PTPN11:GRB2:GAB1:PI3K [plasma membrane] (Gallus gallus)
Activated FGFR4:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] (Gallus gallus)
Activated FGFR4:p-FRS2:p-PTPN11 [plasma membrane] (Gallus gallus)
Activated FGFR4:p-FRS2 [plasma membrane] (Gallus gallus)
Activated FGFR4 [plasma membrane] (Gallus gallus)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Gallus gallus)
KLB [plasma membrane] (Gallus gallus)
Activated FGFR4:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] (Gallus gallus)
Activated FGFR4:p-FRS2:p-PTPN11 [plasma membrane] (Gallus gallus)
Activated FGFR4:p-FRS2 [plasma membrane] (Gallus gallus)
Activated FGFR4 [plasma membrane] (Gallus gallus)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Gallus gallus)
KLB [plasma membrane] (Gallus gallus)
FGFR4- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 (Gallus gallus)
Activated FGFR4:p-FRS2:p-PTPN11:GRB2:GAB1:PI3K [plasma membrane] (Gallus gallus)
Activated FGFR4:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] (Gallus gallus)
Activated FGFR4:p-FRS2:p-PTPN11 [plasma membrane] (Gallus gallus)
Activated FGFR4:p-FRS2 [plasma membrane] (Gallus gallus)
Activated FGFR4 [plasma membrane] (Gallus gallus)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Gallus gallus)
KLB [plasma membrane] (Gallus gallus)
FGFR4-associated PI3K phosphorylates PIP2 to PIP3 (Gallus gallus)
Activated FGFR4:p-FRS2:GRB2:GAB1:PI3K [plasma membrane] (Gallus gallus)
Activated FGFR4:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Gallus gallus)
Activated FGFR4:p-FRS2 [plasma membrane] (Gallus gallus)
Activated FGFR4 [plasma membrane] (Gallus gallus)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Gallus gallus)
KLB [plasma membrane] (Gallus gallus)
Phospholipase C-mediated cascade; FGFR4 (Gallus gallus)
Activated FGFR4 binds PLCG1 (Gallus gallus)
Activated FGFR4 [plasma membrane] (Gallus gallus)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Gallus gallus)
KLB [plasma membrane] (Gallus gallus)
activated FGFR4:PLCG1 [plasma membrane] (Gallus gallus)
Activated FGFR4 [plasma membrane] (Gallus gallus)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Gallus gallus)
KLB [plasma membrane] (Gallus gallus)
Activated FGFR4 phosphorylates PLCG1 (Gallus gallus)
activated FGFR4:PLCG1 [plasma membrane] (Gallus gallus)
Activated FGFR4 [plasma membrane] (Gallus gallus)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Gallus gallus)
KLB [plasma membrane] (Gallus gallus)
activated FGFR4:p-4Y-PLCG1 [plasma membrane] (Gallus gallus)
Activated FGFR4 [plasma membrane] (Gallus gallus)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Gallus gallus)
KLB [plasma membrane] (Gallus gallus)
p-4Y-PLCG1 dissociates from activated FGFR4 (Gallus gallus)
Activated FGFR4 [plasma membrane] (Gallus gallus)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Gallus gallus)
KLB [plasma membrane] (Gallus gallus)
activated FGFR4:p-4Y-PLCG1 [plasma membrane] (Gallus gallus)
Activated FGFR4 [plasma membrane] (Gallus gallus)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Gallus gallus)
KLB [plasma membrane] (Gallus gallus)
SHC-mediated cascade:FGFR4 (Gallus gallus)
Activated FGFR4 binds SHC1 (Gallus gallus)
Activated FGFR4 [plasma membrane] (Gallus gallus)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Gallus gallus)
KLB [plasma membrane] (Gallus gallus)
Activated FGFR4:SHC1 [plasma membrane] (Gallus gallus)
Activated FGFR4 [plasma membrane] (Gallus gallus)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Gallus gallus)
KLB [plasma membrane] (Gallus gallus)
Activated FGFR4 phosphorylates SHC1 (Gallus gallus)
Activated FGFR4:SHC1 [plasma membrane] (Gallus gallus)
Activated FGFR4 [plasma membrane] (Gallus gallus)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Gallus gallus)
KLB [plasma membrane] (Gallus gallus)
Activated FGFR4:pY-SHC1 [plasma membrane] (Gallus gallus)
Activated FGFR4 [plasma membrane] (Gallus gallus)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Gallus gallus)
KLB [plasma membrane] (Gallus gallus)
Activated FGFR4:p-SHC1 binds GRB2:SOS1 (Gallus gallus)
Activated FGFR4:pY-SHC1 [plasma membrane] (Gallus gallus)
Activated FGFR4 [plasma membrane] (Gallus gallus)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Gallus gallus)
KLB [plasma membrane] (Gallus gallus)
Activated FGFR4:pY-SHC1:GRB2:SOS1 [plasma membrane] (Gallus gallus)
Activated FGFR4:pY-SHC1 [plasma membrane] (Gallus gallus)
Activated FGFR4 [plasma membrane] (Gallus gallus)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Gallus gallus)
KLB [plasma membrane] (Gallus gallus)
Activated FGFR4:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Gallus gallus)
Activated FGFR4:pY-SHC1:GRB2:SOS1 [plasma membrane] (Gallus gallus)
Activated FGFR4:pY-SHC1 [plasma membrane] (Gallus gallus)
Activated FGFR4 [plasma membrane] (Gallus gallus)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Gallus gallus)
KLB [plasma membrane] (Gallus gallus)
FGFR4 ligand binding and activation (Gallus gallus)
betaKlotho-mediated ligand binding (Gallus gallus)
Autocatalytic phosphorylation of BetaKlotho-bound FGFR4 (Gallus gallus)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Gallus gallus)
KLB [plasma membrane] (Gallus gallus)
FGFR4:HS:KLB:FGF19 [plasma membrane] (Gallus gallus)
KLB [plasma membrane] (Gallus gallus)
FGFR4 binds HS:KLB:FGF19 (Gallus gallus)
FGFR4:HS:KLB:FGF19 [plasma membrane] (Gallus gallus)
KLB [plasma membrane] (Gallus gallus)
KLB [plasma membrane] (Gallus gallus)
Negative regulation of FGFR4 signaling (Gallus gallus)
Activated ERK1/2 threonine-phosphorylates FGFR4-associated FRS2 (Gallus gallus)
Activated FGFR4:FRS2 [plasma membrane] (Gallus gallus)
Activated FGFR4 [plasma membrane] (Gallus gallus)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Gallus gallus)
KLB [plasma membrane] (Gallus gallus)
Activated FGFR4:p-8T-FRS2 [plasma membrane] (Gallus gallus)
Activated FGFR4 [plasma membrane] (Gallus gallus)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Gallus gallus)
KLB [plasma membrane] (Gallus gallus)
CBL ubiquitinates FRS2 and FGFR4 (Gallus gallus)
Activated FGFR4:p-FRS2:p-PPTN11:p-CBL:GRB2 [plasma membrane] (Gallus gallus)
Activated FGFR4:p-FRS2:p-PTPN11 [plasma membrane] (Gallus gallus)
Activated FGFR4:p-FRS2 [plasma membrane] (Gallus gallus)
Activated FGFR4 [plasma membrane] (Gallus gallus)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Gallus gallus)
KLB [plasma membrane] (Gallus gallus)
Ub-Activated FGFR4 complex:Ub-p-FRS2 [plasma membrane] (Gallus gallus)
Activated FGFR4:p-FRS2:p-PPTN11:p-CBL:GRB2 [plasma membrane] (Gallus gallus)
Activated FGFR4:p-FRS2:p-PTPN11 [plasma membrane] (Gallus gallus)
Activated FGFR4:p-FRS2 [plasma membrane] (Gallus gallus)
Activated FGFR4 [plasma membrane] (Gallus gallus)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Gallus gallus)
KLB [plasma membrane] (Gallus gallus)
p-CBL:GRB2 binds p-FRS2:activated FGFR4 (Gallus gallus)
Activated FGFR4:p-FRS2:p-PPTN11:p-CBL:GRB2 [plasma membrane] (Gallus gallus)
Activated FGFR4:p-FRS2:p-PTPN11 [plasma membrane] (Gallus gallus)
Activated FGFR4:p-FRS2 [plasma membrane] (Gallus gallus)
Activated FGFR4 [plasma membrane] (Gallus gallus)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Gallus gallus)
KLB [plasma membrane] (Gallus gallus)
Activated FGFR4:p-FRS2:p-PTPN11 [plasma membrane] (Gallus gallus)
Activated FGFR4:p-FRS2 [plasma membrane] (Gallus gallus)
Activated FGFR4 [plasma membrane] (Gallus gallus)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Gallus gallus)
KLB [plasma membrane] (Gallus gallus)
Signaling by Insulin receptor (Gallus gallus)
Insulin receptor signalling cascade (Gallus gallus)
IRS-mediated signalling (Gallus gallus)
PI3K Cascade (Gallus gallus)
PI3K-containing complexes phosphorylate PIP2 to PIP3 (Gallus gallus)
PI3K-containing complexes [cytosol] (Gallus gallus)
Activated FGFR bound to PI3K [cytosol] (Gallus gallus)
GRB2 and GAB1 bound to activated FGFR and FRS2-alpha [plasma membrane] (Gallus gallus)
Activated FGFR:p-FRS2:p-PTPN11 [plasma membrane] (Gallus gallus)
Activated FGFR:p-FRS2 [plasma membrane] (Gallus gallus)
Activated FGFR [plasma membrane] (Gallus gallus)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Gallus gallus)
KLB [plasma membrane] (Gallus gallus)
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) (Gallus gallus)
IGF1R signaling cascade (Gallus gallus)
IRS-related events triggered by IGF1R (Gallus gallus)
IRS-mediated signalling (Gallus gallus)
PI3K Cascade (Gallus gallus)
PI3K-containing complexes phosphorylate PIP2 to PIP3 (Gallus gallus)
PI3K-containing complexes [cytosol] (Gallus gallus)
Activated FGFR bound to PI3K [cytosol] (Gallus gallus)
GRB2 and GAB1 bound to activated FGFR and FRS2-alpha [plasma membrane] (Gallus gallus)
Activated FGFR:p-FRS2:p-PTPN11 [plasma membrane] (Gallus gallus)
Activated FGFR:p-FRS2 [plasma membrane] (Gallus gallus)
Activated FGFR [plasma membrane] (Gallus gallus)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Gallus gallus)
KLB [plasma membrane] (Gallus gallus)
External Reference Information
External Reference
UniProt:A0A8V0Z2L0
Gene Names
KLB
Reference Genes
BioGPS Gene:425467 KLB
ENSEMBL:ENSGALG00010016414.1
KEGG:gga:425467 KLB
Monarch:425467 KLB
NCBI Gene:425467 KLB
UCSC:A0A8V0Z2L0 KLB
Reference Transcript
RefSeq:XM_003641245.6 KLB
Other Identifiers
425467
GO:0004553
GO:0005104
GO:0005886
GO:0005975
GO:0008284
GO:0008543
GO:0016020
GO:0016787
GO:0017134
GO:0090080
GT_A_87_P162963
GgaAffx.9076.1.S1_at
GgaAffx.94.1.S1_at
Participates
as an input of
FGFR4 binds HS:KLB:FGF19 (Gallus gallus)
as a component of
FGFR4:HS:KLB:FGF19 [plasma membrane] (Gallus gallus)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Gallus gallus)
Inferred From
KLB [plasma membrane]
(Homo sapiens)
Cross References
RefSeq
XP_003641293.4
ENSEMBL
ENSGALG00010016414
,
ENSGALP00010022846
,
ENSGALT00010039574
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