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viral dsRNA:MDA5:NLRC5 [cytosol]
Stable Identifier
R-GGA-1227687
Type
Complex
Species
Gallus gallus
Related Species
Infectious bronchitis virus
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Innate Immune System (Gallus gallus)
RLR (RIG-like receptor) mediated induction of IFN alpha/beta (Gallus gallus)
Activated MDA5 binds IPS-1 (Gallus gallus)
viral dsRNA:MDA5:NLRC5 [cytosol] (Gallus gallus)
Negative Regulation of MDA5 signaling (Gallus gallus)
NLRC5 binds to CARD domain of Mda5 and prevents IPS1 binding (Gallus gallus)
viral dsRNA:MDA5:NLRC5 [cytosol] (Gallus gallus)
Participants
components
IBV dsRNA intermediate form [cytosol]
(Infectious bronchitis virus)
x 2
MDA5 [cytosol]
(Gallus gallus)
x 2
NLRC5 [cytosol]
(Gallus gallus)
Participates
as an output of
NLRC5 binds to CARD domain of Mda5 and prevents IPS1 binding (Gallus gallus)
This entity regulates
Negatively
Activated MDA5 binds IPS-1
(Gallus gallus)
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