Reactome | MCFD2 [ER to Golgi transport vesicle membrane]

MCFD2 [ER to Golgi transport vesicle membrane]

Stable Identifier

R-GGA-1017216

Type

Protein [EntityWithAccessionedSequence]

Species

Gallus gallus

Compartment

ER to Golgi transport vesicle membrane

Synonyms

MCFD2, Q5ZJB5

Locations in the PathwayBrowser

Expand all

Metabolism of proteins (Gallus gallus)

- Post-translational protein modification (Gallus gallus)
  - Asparagine N-linked glycosylation (Gallus gallus)
    - Transport to the Golgi and subsequent modification (Gallus gallus)
      - ER to Golgi Anterograde Transport (Gallus gallus)
        
        COPII-mediated vesicle transport (Gallus gallus)
        
        Nucleotide exchange on RAB1 (Gallus gallus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Gallus gallus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Gallus gallus)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Gallus gallus)
        
        LMAN1:MCFD2:glycosylated FV, FVIII precursor [ER to Golgi transport vesicle membrane] (Gallus gallus)
        
        hexameric LMAN1:MCFD2 [ER to Golgi transport vesicle membrane] (Gallus gallus)
        
        MCFD2 [ER to Golgi transport vesicle membrane] (Gallus gallus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Gallus gallus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Gallus gallus)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Gallus gallus)
        
        LMAN1:MCFD2:glycosylated FV, FVIII precursor [ER to Golgi transport vesicle membrane] (Gallus gallus)
        
        hexameric LMAN1:MCFD2 [ER to Golgi transport vesicle membrane] (Gallus gallus)
        
        MCFD2 [ER to Golgi transport vesicle membrane] (Gallus gallus)
        
        RAB1:GTP binds USO1 and GORASP1:GOLGA2 (Gallus gallus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Gallus gallus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Gallus gallus)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Gallus gallus)
        
        LMAN1:MCFD2:glycosylated FV, FVIII precursor [ER to Golgi transport vesicle membrane] (Gallus gallus)
        
        hexameric LMAN1:MCFD2 [ER to Golgi transport vesicle membrane] (Gallus gallus)
        
        MCFD2 [ER to Golgi transport vesicle membrane] (Gallus gallus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP:USO1 homodimer:GOLGA2:GORASP1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Gallus gallus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Gallus gallus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Gallus gallus)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Gallus gallus)
        
        LMAN1:MCFD2:glycosylated FV, FVIII precursor [ER to Golgi transport vesicle membrane] (Gallus gallus)
        
        hexameric LMAN1:MCFD2 [ER to Golgi transport vesicle membrane] (Gallus gallus)
        
        MCFD2 [ER to Golgi transport vesicle membrane] (Gallus gallus)
        
        Vesicle budding (Gallus gallus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Gallus gallus)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Gallus gallus)
        
        LMAN1:MCFD2:glycosylated FV, FVIII precursor [ER to Golgi transport vesicle membrane] (Gallus gallus)
        
        hexameric LMAN1:MCFD2 [ER to Golgi transport vesicle membrane] (Gallus gallus)
        
        MCFD2 [ER to Golgi transport vesicle membrane] (Gallus gallus)

Vesicle-mediated transport (Gallus gallus)

- Membrane Trafficking (Gallus gallus)
  - ER to Golgi Anterograde Transport (Gallus gallus)
    - COPII-mediated vesicle transport (Gallus gallus)
      - Nucleotide exchange on RAB1 (Gallus gallus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Gallus gallus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Gallus gallus)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Gallus gallus)
        
        LMAN1:MCFD2:glycosylated FV, FVIII precursor [ER to Golgi transport vesicle membrane] (Gallus gallus)
        
        hexameric LMAN1:MCFD2 [ER to Golgi transport vesicle membrane] (Gallus gallus)
        
        MCFD2 [ER to Golgi transport vesicle membrane] (Gallus gallus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Gallus gallus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Gallus gallus)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Gallus gallus)
        
        LMAN1:MCFD2:glycosylated FV, FVIII precursor [ER to Golgi transport vesicle membrane] (Gallus gallus)
        
        hexameric LMAN1:MCFD2 [ER to Golgi transport vesicle membrane] (Gallus gallus)
        
        MCFD2 [ER to Golgi transport vesicle membrane] (Gallus gallus)
      - RAB1:GTP binds USO1 and GORASP1:GOLGA2 (Gallus gallus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Gallus gallus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Gallus gallus)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Gallus gallus)
        
        LMAN1:MCFD2:glycosylated FV, FVIII precursor [ER to Golgi transport vesicle membrane] (Gallus gallus)
        
        hexameric LMAN1:MCFD2 [ER to Golgi transport vesicle membrane] (Gallus gallus)
        
        MCFD2 [ER to Golgi transport vesicle membrane] (Gallus gallus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP:USO1 homodimer:GOLGA2:GORASP1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Gallus gallus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Gallus gallus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Gallus gallus)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Gallus gallus)
        
        LMAN1:MCFD2:glycosylated FV, FVIII precursor [ER to Golgi transport vesicle membrane] (Gallus gallus)
        
        hexameric LMAN1:MCFD2 [ER to Golgi transport vesicle membrane] (Gallus gallus)
        
        MCFD2 [ER to Golgi transport vesicle membrane] (Gallus gallus)
      - Vesicle budding (Gallus gallus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Gallus gallus)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Gallus gallus)
        
        LMAN1:MCFD2:glycosylated FV, FVIII precursor [ER to Golgi transport vesicle membrane] (Gallus gallus)
        
        hexameric LMAN1:MCFD2 [ER to Golgi transport vesicle membrane] (Gallus gallus)
        
        MCFD2 [ER to Golgi transport vesicle membrane] (Gallus gallus)

External Reference Information

External Reference

UniProt:Q5ZJB5

Gene Names

MCFD2

Reference Genes

BioGPS Gene:421413 MCFD2

ENSEMBL:ENSGALG00010019878.1

KEGG:gga:421413 MCFD2

Monarch:421413 MCFD2

NCBI Gene:421413 MCFD2

UCSC:Q5ZJB5 MCFD2

Reference Transcript

Other Identifiers

421413

GO:0005509

GO:0005783

GO:0005794

GO:0010467

GO:0015031

GO:0046872

GT_A_87_P036356

GT_A_87_P220203

GT_Xhyb_Chicken_CO759584_3939

Gga.1404.1.S1_at

GgaAffx.12622.1.S1_s_at

Participates

as a component of

hexameric LMAN1:MCFD2 [ER to Golgi transport vesicle membrane] (Gallus gallus)

Other forms of this molecule

MCFD2 [endoplasmic reticulum membrane]

Inferred From

MCFD2 [ER to Golgi transport vesicle membrane] (Homo sapiens)

Cross References

RefSeq

NP_001006400.1, XP_015139186.1, XP_046769763.1

ENSEMBL

ENSGALP00010028352, ENSGALT00010048032, ENSGALG00010019878

Cite Us!