Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
KDM1A [nucleoplasm]
Stable Identifier
R-DRE-996769
Type
Protein [EntityWithAccessionedSequence]
Species
Danio rerio
Compartment
nucleoplasm
Synonyms
F6NIA2
Locations in the PathwayBrowser
Expand all
Chromatin organization (Danio rerio)
Chromatin modifying enzymes (Danio rerio)
HDACs deacetylate histones (Danio rerio)
HDAC1:2-containing complex binds HDAC2 Inhibitors (Danio rerio)
HDAC1:2-containing complex [nucleoplasm] (Danio rerio)
BHC complex [nucleoplasm] (Danio rerio)
KDM1A [nucleoplasm] (Danio rerio)
CoREST complex [nucleoplasm] (Danio rerio)
KDM1A [nucleoplasm] (Danio rerio)
HDAC1:2-containing complex:HDAC2 inhibitors [nucleoplasm] (Danio rerio)
HDAC1:2-containing complex [nucleoplasm] (Danio rerio)
BHC complex [nucleoplasm] (Danio rerio)
KDM1A [nucleoplasm] (Danio rerio)
CoREST complex [nucleoplasm] (Danio rerio)
KDM1A [nucleoplasm] (Danio rerio)
HDAC1:2-containing complex deacetylate histones (Danio rerio)
HDAC1:2-containing complex [nucleoplasm] (Danio rerio)
BHC complex [nucleoplasm] (Danio rerio)
KDM1A [nucleoplasm] (Danio rerio)
CoREST complex [nucleoplasm] (Danio rerio)
KDM1A [nucleoplasm] (Danio rerio)
HDAC1:2-containing complex:HDAC2 inhibitors [nucleoplasm] (Danio rerio)
HDAC1:2-containing complex [nucleoplasm] (Danio rerio)
BHC complex [nucleoplasm] (Danio rerio)
KDM1A [nucleoplasm] (Danio rerio)
CoREST complex [nucleoplasm] (Danio rerio)
KDM1A [nucleoplasm] (Danio rerio)
HDMs demethylate histones (Danio rerio)
KDM1A, KDM1B demethylate Me2K5-histone H3 (Danio rerio)
KDM1A [nucleoplasm] (Danio rerio)
KDM1A, KDM1B demethylate MeK5-histone H3 (Danio rerio)
KDM1A [nucleoplasm] (Danio rerio)
Hemostasis (Danio rerio)
Factors involved in megakaryocyte development and platelet production (Danio rerio)
REST recruits the BHC complex (Danio rerio)
BHC complex [nucleoplasm] (Danio rerio)
KDM1A [nucleoplasm] (Danio rerio)
BHC complex:REST:REST DNA binding sites [nucleoplasm] (Danio rerio)
BHC complex [nucleoplasm] (Danio rerio)
KDM1A [nucleoplasm] (Danio rerio)
Signal Transduction (Danio rerio)
Signaling by Nuclear Receptors (Danio rerio)
ESR-mediated signaling (Danio rerio)
Estrogen-dependent gene expression (Danio rerio)
KDM1A demethylates H3 on MYC and BCL genes in response to estrogen (Danio rerio)
KDM1A [nucleoplasm] (Danio rerio)
MYC gene, BCL2 gene: H3K9me2, HIST1H2AC nucleosome:ESR1:ESTG:KDM1A [nucleoplasm] (Danio rerio)
KDM1A [nucleoplasm] (Danio rerio)
KDM1A is recruited to MYC and BCL2 genes (Danio rerio)
KDM1A [nucleoplasm] (Danio rerio)
MYC gene, BCL2 gene: H3K9me2, HIST1H2AC nucleosome:ESR1:ESTG:KDM1A [nucleoplasm] (Danio rerio)
KDM1A [nucleoplasm] (Danio rerio)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Danio rerio)
Signaling by Rho GTPases (Danio rerio)
RHO GTPase Effectors (Danio rerio)
RHO GTPases activate PKNs (Danio rerio)
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 (Danio rerio)
Demethylase KDM1A binds KLK2 and KLK3 promoters (Danio rerio)
KDM1A [nucleoplasm] (Danio rerio)
p-T774-PKN1:AR:Androgen:KLK2,KLK3 Gene:Nucleosome with p-T12,Me2K-10-H3:KDM1A [nucleoplasm] (Danio rerio)
KDM1A [nucleoplasm] (Danio rerio)
KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters (Danio rerio)
KDM1A [nucleoplasm] (Danio rerio)
p-T774-PKN1:AR:Androgen:KLK2,KLK3 Gene:Nucleosome with p-T12,Me2K-10-H3:KDM1A [nucleoplasm] (Danio rerio)
KDM1A [nucleoplasm] (Danio rerio)
p-T774-PKN1:AR:Androgen:KLK2,KLK3 Gene:Nucleosome with p-T12,MeK-10-H3:KDM1A [nucleoplasm] (Danio rerio)
KDM1A [nucleoplasm] (Danio rerio)
KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters (Danio rerio)
KDM1A [nucleoplasm] (Danio rerio)
p-T774-PKN1:AR:Androgen:KLK2,KLK3 Gene:Nucleosome with p-T12,MeK-10-H3:KDM1A [nucleoplasm] (Danio rerio)
KDM1A [nucleoplasm] (Danio rerio)
External Reference Information
External Reference
UniProt:F6NIA2
Reference Genes
BioGPS Gene:558450
ENSEMBL:ENSDARG00000060679
KEGG:dre:558450
Monarch:558450
NCBI Gene:558450
UCSC:F6NIA2
Reference Transcript
RefSeq:NM_001242995.1
Other Identifiers
13052522
558450
A_15_P120532
A_15_P203206
CUST_10144_PI428451958
CUST_3151_PI428451953
CUST_3152_PI428451953
CUST_3153_PI428451953
CUST_3154_PI428451953
CUST_6201_PI424165604
CUST_6202_PI424165604
CUST_6203_PI424165604
CUST_6204_PI424165604
CUST_6205_PI424165604
CUST_6206_PI424165604
CUST_6207_PI424165604
CUST_6208_PI424165604
DRER12926
DRER47310
DRER47532
DRER47612
DRER47715
DRER47817
DRER47909
Dr.2244.1.A1_at
ENSDART00000085758
ENSDART00000085758_1
ENSDART00000085758_2
ENSDART00000085862
ENSDART00000085862_y_1
ENSDART00000085862_y_2
GO:0005515
GO:0005634
GO:0006355
GO:0016491
GO:0050660
GT_Spec_NM_001242995.1_318475
GT_Xhyb_XM_005158781.1_367765
GT_Xhyb_XM_005158782.1_367775
GT_Xhyb_XM_005158783.1_367785
LOLS15836
XM_679337
XM_681662
ZV700S00003770
Participates
as an output of
KDM1A demethylates H3 on MYC and BCL genes in response to estrogen (Danio rerio)
KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters (Danio rerio)
as an input of
KDM1A is recruited to MYC and BCL2 genes (Danio rerio)
Demethylase KDM1A binds KLK2 and KLK3 promoters (Danio rerio)
as a component of
MYC gene, BCL2 gene: H3K9me2, HIST1H2AC nucleosome:ESR1:ESTG:KDM1A [nucleoplasm] (Danio rerio)
BHC complex [nucleoplasm] (Danio rerio)
p-T774-PKN1:AR:Androgen:KLK2,KLK3 Gene:Nucleosome with p-T12,Me2K-10-H3:KDM1A [nucleoplasm] (Danio rerio)
p-T774-PKN1:AR:Androgen:KLK2,KLK3 Gene:Nucleosome with p-T12,MeK-10-H3:KDM1A [nucleoplasm] (Danio rerio)
CoREST complex [nucleoplasm] (Danio rerio)
Inferred From
KDM1A,KDM1B [nucleoplasm]
(Homo sapiens)
KDM1A [nucleoplasm]
(Homo sapiens)
Cross References
RefSeq
NP_001229924.1
ENSEMBL
ENSDARG00000060679
,
ENSDARP00000080193
,
ENSDART00000085758
ZFIN
ZDB-GENE-030131-7828
© 2026
Reactome
This website requires cookies and the limited processing of your personal data in order to function. By using the site you are agreeing to this as outlined in our
Privacy Notice
.
I agree, dismiss this banner
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text