Reactome | ints2 [nucleoplasm]

ints2 [nucleoplasm]

Stable Identifier

R-DRE-6807448

Type

Protein [EntityWithAccessionedSequence]

Species

Danio rerio

Compartment

nucleoplasm

Synonyms

INTS2, E9QC62

Locations in the PathwayBrowser

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Gene expression (Transcription) (Danio rerio)

- RNA Polymerase II Transcription (Danio rerio)
  - RNA polymerase II transcribes snRNA genes (Danio rerio)
    - Integrator complex processes the 3' end of snRNA (Danio rerio)
      - Integrator [nucleoplasm] (Danio rerio)
        
        ints2 [nucleoplasm] (Danio rerio)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:CBCAP:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Danio rerio)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Danio rerio)
        
        Integrator [nucleoplasm] (Danio rerio)
        
        ints2 [nucleoplasm] (Danio rerio)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:Initiation factors:snRNA gene [nucleoplasm] (Danio rerio)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Danio rerio)
        
        Integrator [nucleoplasm] (Danio rerio)
        
        ints2 [nucleoplasm] (Danio rerio)
    - Pre-snRNA is elongated and capped with 7-methylguanosine (Danio rerio)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Danio rerio)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Danio rerio)
        
        Integrator [nucleoplasm] (Danio rerio)
        
        ints2 [nucleoplasm] (Danio rerio)
      - RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Danio rerio)
        
        RNA polymerase II (phospho-Ser5,7 CTD):RDRP1A,B:RDRP2:RPAP2:Integrator:LEC [nucleoplasm] (Danio rerio)
        
        Integrator [nucleoplasm] (Danio rerio)
        
        ints2 [nucleoplasm] (Danio rerio)
    - Pre-snRNA transcript initiation, Integrator binding, LEC binding (Danio rerio)
      - Integrator [nucleoplasm] (Danio rerio)
        
        ints2 [nucleoplasm] (Danio rerio)
      - RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Danio rerio)
        
        RNA polymerase II (phospho-Ser5,7 CTD):RDRP1A,B:RDRP2:RPAP2:Integrator:LEC [nucleoplasm] (Danio rerio)
        
        Integrator [nucleoplasm] (Danio rerio)
        
        ints2 [nucleoplasm] (Danio rerio)

External Reference Information

External Reference

UniProt:E9QC62

Gene Names

ints2

Reference Genes

BioGPS Gene:553563 ints2

ENSEMBL:ENSDARG00000069085

KEGG:dre:553563 ints2

Monarch:553563 ints2

NCBI Gene:553563 ints2

UCSC:E9QC62 ints2

Reference Transcript

RefSeq:NM_001020542.2 ints2

Other Identifiers

12969108

13276598

13282800

13284308

13284568

553563

A_15_P157911

A_15_P161126

A_15_P229246

A_15_P429205

A_15_P622716

CUST_1070_PI428451958

CUST_17163_PI428451953

DRER03008

DRER11249

DRER42073

Dr.13598.1.A1_at

ENSDART00000023545

ENSDART00000023545_1

ENSDART00000023545_2

ENSDART00000078791

GO:0016073

GO:0016180

GO:0032039

GT_Spec_NM_001020542.2_274295

LOLG382

LOLG383

LOLS05596

MADDr01004347

NM_001020542

TC263171

XM_685139

ZV700S00001061

Participates

as a component of

Integrator [nucleoplasm] (Danio rerio)

Inferred From

INTS2 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_001018378.2

ENSEMBL

ENSDART00000143487, ENSDARP00000121278, ENSDARG00000069085

ZFIN

ZDB-GENE-050522-148

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