Reactome | faap100 [nucleoplasm]

faap100 [nucleoplasm]

Stable Identifier

R-DRE-419545

Type

Protein [EntityWithAccessionedSequence]

Species

Danio rerio

Compartment

nucleoplasm

Synonyms

FAAP100, U3JAR8

Locations in the PathwayBrowser

Expand all

DNA Repair (Danio rerio)

- Fanconi Anemia Pathway (Danio rerio)
  - DNA nucleases bind monoubiquitinated ID2 complex (Danio rerio)
    - MonoUb:K561,p-T691,S717-FANCD2:MonoUb:K523,p-4S-FANCI:FA Core Complex:ICL-DNA [nucleoplasm] (Danio rerio)
      - p-FA Core Complex:ICL-DNA [nucleoplasm] (Danio rerio)
        
        p-FA Core Complex [nucleoplasm] (Danio rerio)
        
        faap100 [nucleoplasm] (Danio rerio)
    - MonoUb:K561,p-T691,S717-FANCD2:MonoUb:K523,p-4S-FANCI:FA Core Complex:ICL-DNA:Unhooking nucleases [nucleoplasm] (Danio rerio)
      - MonoUb:K561,p-T691,S717-FANCD2:MonoUb:K523,p-4S-FANCI:FA Core Complex:ICL-DNA [nucleoplasm] (Danio rerio)
        
        p-FA Core Complex:ICL-DNA [nucleoplasm] (Danio rerio)
        
        p-FA Core Complex [nucleoplasm] (Danio rerio)
        
        faap100 [nucleoplasm] (Danio rerio)
  - DNA nucleases unhook the interstrand crosslink (ICL) (Danio rerio)
    - MonoUb:K561,p-T691,S717-FANCD2:MonoUb:K523,p-4S-FANCI:FA Core Complex:ICL-DNA:Unhooking nucleases [nucleoplasm] (Danio rerio)
      - MonoUb:K561,p-T691,S717-FANCD2:MonoUb:K523,p-4S-FANCI:FA Core Complex:ICL-DNA [nucleoplasm] (Danio rerio)
        
        p-FA Core Complex:ICL-DNA [nucleoplasm] (Danio rerio)
        
        p-FA Core Complex [nucleoplasm] (Danio rerio)
        
        faap100 [nucleoplasm] (Danio rerio)
    - MonoUb:K561,p-T691,S717-FANCD2:MonoUb:K523,p-4S-FANCI:FA Core Complex:Unhooked ICL-DNA [nucleoplasm] (Danio rerio)
      - FA core complex [nucleoplasm] (Danio rerio)
        
        faap100 [nucleoplasm] (Danio rerio)
  - Monoubiquitination of FANCD2:FANCI (Danio rerio)
    - MonoUb:K561,p-T691,S717-FANCD2:MonoUb:K523,p-4S-FANCI:FA Core Complex:ICL-DNA [nucleoplasm] (Danio rerio)
      - p-FA Core Complex:ICL-DNA [nucleoplasm] (Danio rerio)
        
        p-FA Core Complex [nucleoplasm] (Danio rerio)
        
        faap100 [nucleoplasm] (Danio rerio)
    - p-FANCD2:p-FANCI:UBE2T:p-FA Core Complex:ICL-DNA [nucleoplasm] (Danio rerio)
      - p-FA Core Complex:ICL-DNA [nucleoplasm] (Danio rerio)
        
        p-FA Core Complex [nucleoplasm] (Danio rerio)
        
        faap100 [nucleoplasm] (Danio rerio)
  - POLN binds ICL-DNA (Danio rerio)
    - MonoUb:K561,p-T691,S717-FANCD2:MonoUb:K523,p-4S-FANCI:FA Core Complex:Unhooked ICL-DNA [nucleoplasm] (Danio rerio)
      - FA core complex [nucleoplasm] (Danio rerio)
        
        faap100 [nucleoplasm] (Danio rerio)
    - MonoUb:K561,p-T691,S717-FANCD2:MonoUb:K523,p-4S-FANCI:FA Core Complex:Unhooked ICL-DNA:POLN [nucleoplasm] (Danio rerio)
      - MonoUb:K561,p-T691,S717-FANCD2:MonoUb:K523,p-4S-FANCI:FA Core Complex:Unhooked ICL-DNA [nucleoplasm] (Danio rerio)
        
        FA core complex [nucleoplasm] (Danio rerio)
        
        faap100 [nucleoplasm] (Danio rerio)

External Reference Information

External Reference

UniProt:U3JAR8

Gene Names

faap100

Reference Genes

BioGPS Gene:100001169 faap100

ENSEMBL:ENSDARG00000079457

KEGG:dre:100001169 faap100

Monarch:100001169 faap100

NCBI Gene:100001169 faap100

UCSC:U3JAR8 faap100

Reference Transcript

RefSeq:XM_017358533.3 faap100

Other Identifiers

100001169

12985885

A_15_P392265

A_15_P528197

CUST_10315_PI428451953

DRER05433

DRER50898

ENSDART00000044812

GO:0005515

GO:0036297

GO:0043240

GT_Spec_XM_001341191.4_413505

Participates

as a component of

Other forms of this molecule

faap100 [cytosol]

Inferred From

FAAP100 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

XP_017214022.2

ENSEMBL

ENSDARP00000127337, ENSDART00000152955, ENSDARG00000079457

ZFIN

ZDB-GENE-130603-100