Reactome | FAAP100 [nucleoplasm]

FAAP100 [nucleoplasm]

Stable Identifier

R-HSA-419545

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Fanconi anemia-associated protein of 100 kDa, FP100_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q0VG06 FAAP100

Gene Names

FAAP100, C17orf70

Chain

chain:1-881

Reference Genes

BioGPS Gene:80233 FAAP100

COSMIC (genes):FAAP100 FAAP100

CTD Gene:80233 FAAP100

dbSNP Gene:80233 FAAP100

ENSEMBL:ENSG00000185504 FAAP100

HGNC:26171 FAAP100

KEGG:hsa:80233 FAAP100

Monarch:80233 FAAP100

NCBI Gene:80233 FAAP100

OMIM:611301 FAAP100

UCSC:Q0VG06 FAAP100

Reference Transcript

Participates

as a component of

as an input of

FA core complex assembles at DNA interstrand crosslinks (ICLs) (Homo sapiens)

Other forms of this molecule

FAAP100 [cytosol]

Inferred To

FAAP100 [nucleoplasm] (Bos taurus)

FAAP100 [nucleoplasm] (Canis familiaris)

FAAP100 [nucleoplasm] (Gallus gallus)

FAAP100 [nucleoplasm] (Sus scrofa)

Faap100 [nucleoplasm] (Mus musculus)

Faap100 [nucleoplasm] (Rattus norvegicus)

Ghost homologue of FAAP100 [nucleoplasm] (Xenopus tropicalis)

Cross References

ENSEMBL

ENSG00000185504, ENST00000327787, ENSP00000333283

OpenTargets

ENSG00000185504

GeneCards

FAAP100

HPA

ENSG00000185504-FAAP100

PRO

Q0VG06

Pharos - Targets

Q0VG06

GlyGen

Q0VG06

PDB

7KZP, 7KZQ, 7KZR, 7KZS, 7KZT, 7KZV

Interactors (12)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O15360 FANCA	2	FANCA [cytosol] (R-HSA-420796) FANCA [nucleoplasm] (R-HSA-419541)	0.662	4
UniProt:Q8NB91 FANCB	2	FANCB [cytosol] (R-HSA-420791) FANCB [nucleoplasm] (R-HSA-419528)	0.556	4
UniProt:Q969T3 SNX21			0.527	3
UniProt:Q96PV0 SYNGAP1	1	SYNGAP1 [cytosol] (R-HSA-5658217)	0.527	3
UniProt:Q9UJT2 TSKS			0.527	2
UniProt:Q96KS9 F167A			0.527	2
UniProt:Q96T91 GPHA2	1	GPHA2 [extracellular region] (R-HSA-8942422)	0.527	2
UniProt:O95721 SNAP29	3	SNAP29 [azurophil granule membrane] (R-HSA-6799359) SNAP29 [plasma membrane] (R-HSA-2029020) SNAP29 [Golgi membrane] (R-HSA-6810997)	0.527	2
UniProt:Q96ES7 SGF29	1	SGF29 [nucleoplasm] (R-HSA-3662279)	0.527	4
UniProt:Q8WTQ7 GRK7	1	GRK7 [photoreceptor disc membrane] (R-HSA-6787797)	0.499	2
UniProt:Q53S33 BOLA3			0.499	2
UniProt:Q9NW38 FANCL	2	FANCL [cytosol] (R-HSA-420789) FANCL [nucleoplasm] (R-HSA-419520)	0.482	2