Reactome | acta1a [cytosol]

acta1a [cytosol]

Stable Identifier

R-DRE-390534

Type

Protein [EntityWithAccessionedSequence]

Species

Danio rerio

Compartment

cytosol

Synonyms

ACTA1, Q567E8

Locations in the PathwayBrowser

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Cell-Cell communication (Danio rerio)

- Cell junction organization (Danio rerio)
  - Cell-cell junction organization (Danio rerio)
    - Adherens junctions interactions (Danio rerio)
      - Activation of STAT3 by cadherin engagement (Danio rerio)
        
        CDH1 forms homotypic trans-dimers (Danio rerio)
        
        Homotypic CDH1 cis-cluster:F-actin:VCL [plasma membrane] (Danio rerio)
        
        Homotypic CDH1 cis-cluster:F-actin [plasma membrane] (Danio rerio)
        
        F-actin (all) [cytosol] (Danio rerio)
        
        actins:ATP [cytosol] (Danio rerio)
        
        (ACTA1,ACTC1),(ACTB,ACTG1),(ACTA2,ACTG2) (Danio rerio)
        
        alpha Actin [cytosol] (Danio rerio)
        
        acta1a [cytosol] (Danio rerio)
        
        Homotypic CDH1 trans-dimer cluster [plasma membrane] (Danio rerio)
        
        Homotypic CDH1 trans-dimer [plasma membrane] (Danio rerio)
        
        Man,Man9GlucNAc2,p-3S-CDH1:CTNNB1,JUP:CTNNA1:CTNND1:F-actin:VCL [plasma membrane] (Danio rerio)
        
        F-actin (all) [cytosol] (Danio rerio)
        
        actins:ATP [cytosol] (Danio rerio)
        
        (ACTA1,ACTC1),(ACTB,ACTG1),(ACTA2,ACTG2) (Danio rerio)
        
        alpha Actin [cytosol] (Danio rerio)
        
        acta1a [cytosol] (Danio rerio)
        
        trans-homotypic CDH1 cluster:F-actin:VCL [plasma membrane] (Danio rerio)
        
        F-actin (all) [cytosol] (Danio rerio)
        
        actins:ATP [cytosol] (Danio rerio)
        
        (ACTA1,ACTC1),(ACTB,ACTG1),(ACTA2,ACTG2) (Danio rerio)
        
        alpha Actin [cytosol] (Danio rerio)
        
        acta1a [cytosol] (Danio rerio)
        
        CDH1-associated CTNNA1 binds F-actin (Danio rerio)
        
        F-actin (all) [cytosol] (Danio rerio)
        
        actins:ATP [cytosol] (Danio rerio)
        
        (ACTA1,ACTC1),(ACTB,ACTG1),(ACTA2,ACTG2) (Danio rerio)
        
        alpha Actin [cytosol] (Danio rerio)
        
        acta1a [cytosol] (Danio rerio)
        
        Homotypic CDH1 cis-cluster:F-actin [plasma membrane] (Danio rerio)
        
        F-actin (all) [cytosol] (Danio rerio)
        
        actins:ATP [cytosol] (Danio rerio)
        
        (ACTA1,ACTC1),(ACTB,ACTG1),(ACTA2,ACTG2) (Danio rerio)
        
        alpha Actin [cytosol] (Danio rerio)
        
        acta1a [cytosol] (Danio rerio)
        
        CDH1-associated CTNNA1 binds VCL (Danio rerio)
        
        Homotypic CDH1 cis-cluster:F-actin [plasma membrane] (Danio rerio)
        
        F-actin (all) [cytosol] (Danio rerio)
        
        actins:ATP [cytosol] (Danio rerio)
        
        (ACTA1,ACTC1),(ACTB,ACTG1),(ACTA2,ACTG2) (Danio rerio)
        
        alpha Actin [cytosol] (Danio rerio)
        
        acta1a [cytosol] (Danio rerio)
        
        Homotypic CDH1 cis-cluster:F-actin:VCL [plasma membrane] (Danio rerio)
        
        Homotypic CDH1 cis-cluster:F-actin [plasma membrane] (Danio rerio)
        
        F-actin (all) [cytosol] (Danio rerio)
        
        actins:ATP [cytosol] (Danio rerio)
        
        (ACTA1,ACTC1),(ACTB,ACTG1),(ACTA2,ACTG2) (Danio rerio)
        
        alpha Actin [cytosol] (Danio rerio)
        
        acta1a [cytosol] (Danio rerio)
        
        Cell-to-cell contact through homophilic cadherin interactions inhibits RAC1/CDC42 ubiquitination (Danio rerio)
        
        Engaged CDH1,(CDH11) [plasma membrane] (Danio rerio)
        
        Homotypic CDH1 trans-dimer cluster [plasma membrane] (Danio rerio)
        
        Homotypic CDH1 trans-dimer [plasma membrane] (Danio rerio)
        
        Man,Man9GlucNAc2,p-3S-CDH1:CTNNB1,JUP:CTNNA1:CTNND1:F-actin:VCL [plasma membrane] (Danio rerio)
        
        F-actin (all) [cytosol] (Danio rerio)
        
        actins:ATP [cytosol] (Danio rerio)
        
        (ACTA1,ACTC1),(ACTB,ACTG1),(ACTA2,ACTG2) (Danio rerio)
        
        alpha Actin [cytosol] (Danio rerio)
        
        acta1a [cytosol] (Danio rerio)
      - Regulation of Homotypic Cell-Cell Adhesion (Danio rerio)
        
        Regulation of Expression and Function of Type I Classical Cadherins (Danio rerio)
        
        Regulation of CDH1 Expression and Function (Danio rerio)
        
        Regulation of CDH1 Function (Danio rerio)
        
        CDH1 forms homotypic trans-dimers (Danio rerio)
        
        Homotypic CDH1 cis-cluster:F-actin:VCL [plasma membrane] (Danio rerio)
        
        Homotypic CDH1 cis-cluster:F-actin [plasma membrane] (Danio rerio)
        
        F-actin (all) [cytosol] (Danio rerio)
        
        actins:ATP [cytosol] (Danio rerio)
        
        (ACTA1,ACTC1),(ACTB,ACTG1),(ACTA2,ACTG2) (Danio rerio)
        
        alpha Actin [cytosol] (Danio rerio)
        
        acta1a [cytosol] (Danio rerio)
        
        Homotypic CDH1 trans-dimer cluster [plasma membrane] (Danio rerio)
        
        Homotypic CDH1 trans-dimer [plasma membrane] (Danio rerio)
        
        Man,Man9GlucNAc2,p-3S-CDH1:CTNNB1,JUP:CTNNA1:CTNND1:F-actin:VCL [plasma membrane] (Danio rerio)
        
        F-actin (all) [cytosol] (Danio rerio)
        
        actins:ATP [cytosol] (Danio rerio)
        
        (ACTA1,ACTC1),(ACTB,ACTG1),(ACTA2,ACTG2) (Danio rerio)
        
        alpha Actin [cytosol] (Danio rerio)
        
        acta1a [cytosol] (Danio rerio)
        
        trans-homotypic CDH1 cluster:F-actin:VCL [plasma membrane] (Danio rerio)
        
        F-actin (all) [cytosol] (Danio rerio)
        
        actins:ATP [cytosol] (Danio rerio)
        
        (ACTA1,ACTC1),(ACTB,ACTG1),(ACTA2,ACTG2) (Danio rerio)
        
        alpha Actin [cytosol] (Danio rerio)
        
        acta1a [cytosol] (Danio rerio)
        
        CDH1-associated CTNNA1 binds F-actin (Danio rerio)
        
        F-actin (all) [cytosol] (Danio rerio)
        
        actins:ATP [cytosol] (Danio rerio)
        
        (ACTA1,ACTC1),(ACTB,ACTG1),(ACTA2,ACTG2) (Danio rerio)
        
        alpha Actin [cytosol] (Danio rerio)
        
        acta1a [cytosol] (Danio rerio)
        
        Homotypic CDH1 cis-cluster:F-actin [plasma membrane] (Danio rerio)
        
        F-actin (all) [cytosol] (Danio rerio)
        
        actins:ATP [cytosol] (Danio rerio)
        
        (ACTA1,ACTC1),(ACTB,ACTG1),(ACTA2,ACTG2) (Danio rerio)
        
        alpha Actin [cytosol] (Danio rerio)
        
        acta1a [cytosol] (Danio rerio)
        
        CDH1-associated CTNNA1 binds VCL (Danio rerio)
        
        Homotypic CDH1 cis-cluster:F-actin [plasma membrane] (Danio rerio)
        
        F-actin (all) [cytosol] (Danio rerio)
        
        actins:ATP [cytosol] (Danio rerio)
        
        (ACTA1,ACTC1),(ACTB,ACTG1),(ACTA2,ACTG2) (Danio rerio)
        
        alpha Actin [cytosol] (Danio rerio)
        
        acta1a [cytosol] (Danio rerio)
        
        Homotypic CDH1 cis-cluster:F-actin:VCL [plasma membrane] (Danio rerio)
        
        Homotypic CDH1 cis-cluster:F-actin [plasma membrane] (Danio rerio)
        
        F-actin (all) [cytosol] (Danio rerio)
        
        actins:ATP [cytosol] (Danio rerio)
        
        (ACTA1,ACTC1),(ACTB,ACTG1),(ACTA2,ACTG2) (Danio rerio)
        
        alpha Actin [cytosol] (Danio rerio)
        
        acta1a [cytosol] (Danio rerio)

Muscle contraction (Danio rerio)

- Striated Muscle Contraction (Danio rerio)
  - ATP Hydrolysis By Myosin (Danio rerio)
    - ADP:Calcium Bound Sarcomere Protein Complex [cytosol] (Danio rerio)
      - Thin Filament With Troponin Bound Calcium [cytosol] (Danio rerio)
        
        alpha Actin Chain [cytosol] (Danio rerio)
        
        alpha Actin [cytosol] (Danio rerio)
        
        acta1a [cytosol] (Danio rerio)
    - ATP:Calcium Bound Sarcomere Protein Complex [cytosol] (Danio rerio)
      - Thin Filament With Troponin Bound Calcium [cytosol] (Danio rerio)
        
        alpha Actin Chain [cytosol] (Danio rerio)
        
        alpha Actin [cytosol] (Danio rerio)
        
        acta1a [cytosol] (Danio rerio)
  - Calcium Binds Troponin-C (Danio rerio)
    - Calcium Bound Sarcomere Protein Complex [cytosol] (Danio rerio)
      - Thin Filament With Troponin Bound Calcium [cytosol] (Danio rerio)
        
        alpha Actin Chain [cytosol] (Danio rerio)
        
        alpha Actin [cytosol] (Danio rerio)
        
        acta1a [cytosol] (Danio rerio)
    - Inactive Sarcomere Protein Complex [cytosol] (Danio rerio)
      - Thin Filament [cytosol] (Danio rerio)
        
        alpha Actin Chain [cytosol] (Danio rerio)
        
        alpha Actin [cytosol] (Danio rerio)
        
        acta1a [cytosol] (Danio rerio)
  - Myosin Binds ATP (Danio rerio)
    - ATP:Calcium Bound Sarcomere Protein Complex [cytosol] (Danio rerio)
      - Thin Filament With Troponin Bound Calcium [cytosol] (Danio rerio)
        
        alpha Actin Chain [cytosol] (Danio rerio)
        
        alpha Actin [cytosol] (Danio rerio)
        
        acta1a [cytosol] (Danio rerio)
    - Calcium Bound Sarcomere Protein Complex [cytosol] (Danio rerio)
      - Thin Filament With Troponin Bound Calcium [cytosol] (Danio rerio)
        
        alpha Actin Chain [cytosol] (Danio rerio)
        
        alpha Actin [cytosol] (Danio rerio)
        
        acta1a [cytosol] (Danio rerio)
  - Release Of ADP From Myosin (Danio rerio)
    - ADP:Calcium Bound Sarcomere Protein Complex [cytosol] (Danio rerio)
      - Thin Filament With Troponin Bound Calcium [cytosol] (Danio rerio)
        
        alpha Actin Chain [cytosol] (Danio rerio)
        
        alpha Actin [cytosol] (Danio rerio)
        
        acta1a [cytosol] (Danio rerio)
    - Calcium Bound Sarcomere Protein Complex [cytosol] (Danio rerio)
      - Thin Filament With Troponin Bound Calcium [cytosol] (Danio rerio)
        
        alpha Actin Chain [cytosol] (Danio rerio)
        
        alpha Actin [cytosol] (Danio rerio)
        
        acta1a [cytosol] (Danio rerio)

External Reference Information

External Reference

UniProt:Q567E8

Gene Names

acta1a

Reference Genes

BioGPS Gene:550445 acta1a

CTD Gene:550445 acta1a

ENSEMBL:ENSDARG00000036371

Monarch:550445 acta1a

NCBI Gene:550445 acta1a

UCSC:Q567E8 acta1a

Reference Transcript

RefSeq:NM_001017750.1 acta1a

Participates

as a member of

alpha Actin [cytosol] (Danio rerio)

Inferred From

ACTA1 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_001017750.1

ZFIN

ZDB-GENE-050417-267

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