Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
apbb1ip [cytosol]
Stable Identifier
R-DRE-354081
Type
Protein [EntityWithAccessionedSequence]
Species
Danio rerio
Compartment
cytosol
Synonyms
APBB1IP, Q6PFT9
Locations in the PathwayBrowser
Expand all
Hemostasis (Danio rerio)
Platelet activation, signaling and aggregation (Danio rerio)
Platelet Aggregation (Plug Formation) (Danio rerio)
Integrin signaling (Danio rerio)
Autophosphorylation of PTK2 at Y397 (Danio rerio)
Talin:RIAM complex: ECM ligands:Integrin alphaIIb beta3:Active (p-Y419)- SRC:PTK2 [plasma membrane] (Danio rerio)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Danio rerio)
Talin:RIAM complex [plasma membrane] (Danio rerio)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Danio rerio)
apbb1ip [cytosol] (Danio rerio)
Talin:RIAM complex:ECM ligands: alphaIIb beta3:Active p-Y419-SRC:pY397-PTK2 [plasma membrane] (Danio rerio)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Danio rerio)
Talin:RIAM complex [plasma membrane] (Danio rerio)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Danio rerio)
apbb1ip [cytosol] (Danio rerio)
Autophosphorylation of SRC (Danio rerio)
Talin:RIAM complex:ECM ligands: 2X(Integrin alphaIIb beta3:SRC) [plasma membrane] (Danio rerio)
Talin:RIAM complex [plasma membrane] (Danio rerio)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Danio rerio)
apbb1ip [cytosol] (Danio rerio)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Danio rerio)
Talin:RIAM complex [plasma membrane] (Danio rerio)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Danio rerio)
apbb1ip [cytosol] (Danio rerio)
Clustering of Integrin alphaIIb beta3 complexes (Danio rerio)
Focal complex [plasma membrane] (Danio rerio)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Danio rerio)
Talin:RIAM complex [plasma membrane] (Danio rerio)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Danio rerio)
apbb1ip [cytosol] (Danio rerio)
Talin:RIAM complex:ECM ligands: 2X(Integrin alphaIIb beta3:p(Y530)-SRC:CSK) [plasma membrane] (Danio rerio)
Talin:RIAM complex [plasma membrane] (Danio rerio)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Danio rerio)
apbb1ip [cytosol] (Danio rerio)
GRB2:SOS provides linkage to MAPK signaling for Integrins (Danio rerio)
Interaction of SOS with GRB2 bound to FADK1 (Danio rerio)
GRB2 bound to pPTK2 in Focal adhesion [plasma membrane] (Danio rerio)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Danio rerio)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Danio rerio)
Talin:RIAM complex [plasma membrane] (Danio rerio)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Danio rerio)
apbb1ip [cytosol] (Danio rerio)
GRB2:SOS:p-PTK2:Focal adhesion [plasma membrane] (Danio rerio)
GRB2 bound to pPTK2 in Focal adhesion [plasma membrane] (Danio rerio)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Danio rerio)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Danio rerio)
Talin:RIAM complex [plasma membrane] (Danio rerio)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Danio rerio)
apbb1ip [cytosol] (Danio rerio)
Recruitment of GRB2 to p-PTK2 (Danio rerio)
GRB2 bound to pPTK2 in Focal adhesion [plasma membrane] (Danio rerio)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Danio rerio)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Danio rerio)
Talin:RIAM complex [plasma membrane] (Danio rerio)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Danio rerio)
apbb1ip [cytosol] (Danio rerio)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Danio rerio)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Danio rerio)
Talin:RIAM complex [plasma membrane] (Danio rerio)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Danio rerio)
apbb1ip [cytosol] (Danio rerio)
Interaction of integrin alphaIIb beta3 with Fibrinogen (Danio rerio)
Focal complex [plasma membrane] (Danio rerio)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Danio rerio)
Talin:RIAM complex [plasma membrane] (Danio rerio)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Danio rerio)
apbb1ip [cytosol] (Danio rerio)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Danio rerio)
Talin:RIAM complex [plasma membrane] (Danio rerio)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Danio rerio)
apbb1ip [cytosol] (Danio rerio)
Phosphorylation of pPTK2 by SRC (Danio rerio)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Danio rerio)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Danio rerio)
Talin:RIAM complex [plasma membrane] (Danio rerio)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Danio rerio)
apbb1ip [cytosol] (Danio rerio)
Talin:RIAM complex:ECM ligands: alphaIIb beta3:Active p-Y419-SRC:pY397-PTK2 [plasma membrane] (Danio rerio)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Danio rerio)
Talin:RIAM complex [plasma membrane] (Danio rerio)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Danio rerio)
apbb1ip [cytosol] (Danio rerio)
Release of CSK from SRC (Danio rerio)
Talin:RIAM complex:ECM ligands: 2X(Integrin alphaIIb beta3:Inactive (p-Y530)-SRC) [plasma membrane] (Danio rerio)
Talin:RIAM complex [plasma membrane] (Danio rerio)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Danio rerio)
apbb1ip [cytosol] (Danio rerio)
Talin:RIAM complex:ECM ligands: 2X(Integrin alphaIIb beta3:p(Y530)-SRC:CSK) [plasma membrane] (Danio rerio)
Talin:RIAM complex [plasma membrane] (Danio rerio)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Danio rerio)
apbb1ip [cytosol] (Danio rerio)
SHC1 bound to integrin alphaIIb beta3 is phosphorylated somehow (Danio rerio)
Integrin alpha IIb beta 3:p-Y530-SRC:CSK:Talin:RIAM complex:p-Y427-SHC [plasma membrane] (Danio rerio)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Danio rerio)
Talin:RIAM complex [plasma membrane] (Danio rerio)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Danio rerio)
apbb1ip [cytosol] (Danio rerio)
Integrin alphaIIb beta 3:p(Y530)-SRC:CSK:Talin:RIAM complex:SHC [plasma membrane] (Danio rerio)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Danio rerio)
Talin:RIAM complex [plasma membrane] (Danio rerio)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Danio rerio)
apbb1ip [cytosol] (Danio rerio)
SYK activation by SRC (Danio rerio)
Talin:RIAM:ECM ligands:2X (Integrin alphaIIb beta3:Active (p-Y419)-SRC):SYK [plasma membrane] (Danio rerio)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Danio rerio)
Talin:RIAM complex [plasma membrane] (Danio rerio)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Danio rerio)
apbb1ip [cytosol] (Danio rerio)
Talin:RIAM:ECM ligands:2X(Integrin alphaIIb beta3:Active (p-Y419)-SRC):p(Y)-SYK [plasma membrane] (Danio rerio)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Danio rerio)
Talin:RIAM complex [plasma membrane] (Danio rerio)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Danio rerio)
apbb1ip [cytosol] (Danio rerio)
SYK binds to integrin alphaIIb beta3 (Danio rerio)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Danio rerio)
Talin:RIAM complex [plasma membrane] (Danio rerio)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Danio rerio)
apbb1ip [cytosol] (Danio rerio)
Talin:RIAM:ECM ligands:2X (Integrin alphaIIb beta3:Active (p-Y419)-SRC):SYK [plasma membrane] (Danio rerio)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Danio rerio)
Talin:RIAM complex [plasma membrane] (Danio rerio)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Danio rerio)
apbb1ip [cytosol] (Danio rerio)
Translocation of RIAM to plasma membrane (Danio rerio)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Danio rerio)
apbb1ip [cytosol] (Danio rerio)
apbb1ip [cytosol] (Danio rerio)
Signal Transduction (Danio rerio)
Integrin signaling (Danio rerio)
Autophosphorylation of PTK2 at Y397 (Danio rerio)
Talin:RIAM complex: ECM ligands:Integrin alphaIIb beta3:Active (p-Y419)- SRC:PTK2 [plasma membrane] (Danio rerio)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Danio rerio)
Talin:RIAM complex [plasma membrane] (Danio rerio)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Danio rerio)
apbb1ip [cytosol] (Danio rerio)
Talin:RIAM complex:ECM ligands: alphaIIb beta3:Active p-Y419-SRC:pY397-PTK2 [plasma membrane] (Danio rerio)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Danio rerio)
Talin:RIAM complex [plasma membrane] (Danio rerio)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Danio rerio)
apbb1ip [cytosol] (Danio rerio)
Autophosphorylation of SRC (Danio rerio)
Talin:RIAM complex:ECM ligands: 2X(Integrin alphaIIb beta3:SRC) [plasma membrane] (Danio rerio)
Talin:RIAM complex [plasma membrane] (Danio rerio)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Danio rerio)
apbb1ip [cytosol] (Danio rerio)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Danio rerio)
Talin:RIAM complex [plasma membrane] (Danio rerio)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Danio rerio)
apbb1ip [cytosol] (Danio rerio)
Clustering of Integrin alphaIIb beta3 complexes (Danio rerio)
Focal complex [plasma membrane] (Danio rerio)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Danio rerio)
Talin:RIAM complex [plasma membrane] (Danio rerio)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Danio rerio)
apbb1ip [cytosol] (Danio rerio)
Talin:RIAM complex:ECM ligands: 2X(Integrin alphaIIb beta3:p(Y530)-SRC:CSK) [plasma membrane] (Danio rerio)
Talin:RIAM complex [plasma membrane] (Danio rerio)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Danio rerio)
apbb1ip [cytosol] (Danio rerio)
GRB2:SOS provides linkage to MAPK signaling for Integrins (Danio rerio)
Interaction of SOS with GRB2 bound to FADK1 (Danio rerio)
GRB2 bound to pPTK2 in Focal adhesion [plasma membrane] (Danio rerio)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Danio rerio)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Danio rerio)
Talin:RIAM complex [plasma membrane] (Danio rerio)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Danio rerio)
apbb1ip [cytosol] (Danio rerio)
GRB2:SOS:p-PTK2:Focal adhesion [plasma membrane] (Danio rerio)
GRB2 bound to pPTK2 in Focal adhesion [plasma membrane] (Danio rerio)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Danio rerio)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Danio rerio)
Talin:RIAM complex [plasma membrane] (Danio rerio)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Danio rerio)
apbb1ip [cytosol] (Danio rerio)
Recruitment of GRB2 to p-PTK2 (Danio rerio)
GRB2 bound to pPTK2 in Focal adhesion [plasma membrane] (Danio rerio)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Danio rerio)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Danio rerio)
Talin:RIAM complex [plasma membrane] (Danio rerio)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Danio rerio)
apbb1ip [cytosol] (Danio rerio)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Danio rerio)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Danio rerio)
Talin:RIAM complex [plasma membrane] (Danio rerio)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Danio rerio)
apbb1ip [cytosol] (Danio rerio)
Interaction of integrin alphaIIb beta3 with Fibrinogen (Danio rerio)
Focal complex [plasma membrane] (Danio rerio)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Danio rerio)
Talin:RIAM complex [plasma membrane] (Danio rerio)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Danio rerio)
apbb1ip [cytosol] (Danio rerio)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Danio rerio)
Talin:RIAM complex [plasma membrane] (Danio rerio)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Danio rerio)
apbb1ip [cytosol] (Danio rerio)
Phosphorylation of pPTK2 by SRC (Danio rerio)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Danio rerio)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Danio rerio)
Talin:RIAM complex [plasma membrane] (Danio rerio)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Danio rerio)
apbb1ip [cytosol] (Danio rerio)
Talin:RIAM complex:ECM ligands: alphaIIb beta3:Active p-Y419-SRC:pY397-PTK2 [plasma membrane] (Danio rerio)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Danio rerio)
Talin:RIAM complex [plasma membrane] (Danio rerio)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Danio rerio)
apbb1ip [cytosol] (Danio rerio)
Release of CSK from SRC (Danio rerio)
Talin:RIAM complex:ECM ligands: 2X(Integrin alphaIIb beta3:Inactive (p-Y530)-SRC) [plasma membrane] (Danio rerio)
Talin:RIAM complex [plasma membrane] (Danio rerio)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Danio rerio)
apbb1ip [cytosol] (Danio rerio)
Talin:RIAM complex:ECM ligands: 2X(Integrin alphaIIb beta3:p(Y530)-SRC:CSK) [plasma membrane] (Danio rerio)
Talin:RIAM complex [plasma membrane] (Danio rerio)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Danio rerio)
apbb1ip [cytosol] (Danio rerio)
SHC1 bound to integrin alphaIIb beta3 is phosphorylated somehow (Danio rerio)
Integrin alpha IIb beta 3:p-Y530-SRC:CSK:Talin:RIAM complex:p-Y427-SHC [plasma membrane] (Danio rerio)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Danio rerio)
Talin:RIAM complex [plasma membrane] (Danio rerio)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Danio rerio)
apbb1ip [cytosol] (Danio rerio)
Integrin alphaIIb beta 3:p(Y530)-SRC:CSK:Talin:RIAM complex:SHC [plasma membrane] (Danio rerio)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Danio rerio)
Talin:RIAM complex [plasma membrane] (Danio rerio)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Danio rerio)
apbb1ip [cytosol] (Danio rerio)
SYK activation by SRC (Danio rerio)
Talin:RIAM:ECM ligands:2X (Integrin alphaIIb beta3:Active (p-Y419)-SRC):SYK [plasma membrane] (Danio rerio)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Danio rerio)
Talin:RIAM complex [plasma membrane] (Danio rerio)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Danio rerio)
apbb1ip [cytosol] (Danio rerio)
Talin:RIAM:ECM ligands:2X(Integrin alphaIIb beta3:Active (p-Y419)-SRC):p(Y)-SYK [plasma membrane] (Danio rerio)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Danio rerio)
Talin:RIAM complex [plasma membrane] (Danio rerio)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Danio rerio)
apbb1ip [cytosol] (Danio rerio)
SYK binds to integrin alphaIIb beta3 (Danio rerio)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Danio rerio)
Talin:RIAM complex [plasma membrane] (Danio rerio)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Danio rerio)
apbb1ip [cytosol] (Danio rerio)
Talin:RIAM:ECM ligands:2X (Integrin alphaIIb beta3:Active (p-Y419)-SRC):SYK [plasma membrane] (Danio rerio)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Danio rerio)
Talin:RIAM complex [plasma membrane] (Danio rerio)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Danio rerio)
apbb1ip [cytosol] (Danio rerio)
Translocation of RIAM to plasma membrane (Danio rerio)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Danio rerio)
apbb1ip [cytosol] (Danio rerio)
apbb1ip [cytosol] (Danio rerio)
MAPK family signaling cascades (Danio rerio)
MAPK1/MAPK3 signaling (Danio rerio)
RAF/MAP kinase cascade (Danio rerio)
MAP2K and MAPK activation (Danio rerio)
Dual mechanism MAP2K inhibitors bind MAP2Ks (Danio rerio)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Danio rerio)
RAF/MAPK scaffolds [cytosol] (Danio rerio)
Focal Adhesion/Focal contacts [plasma membrane] (Danio rerio)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Danio rerio)
Focal complex [plasma membrane] (Danio rerio)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Danio rerio)
Talin:RIAM complex [plasma membrane] (Danio rerio)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Danio rerio)
apbb1ip [cytosol] (Danio rerio)
activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Danio rerio)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Danio rerio)
RAF/MAPK scaffolds [cytosol] (Danio rerio)
Focal Adhesion/Focal contacts [plasma membrane] (Danio rerio)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Danio rerio)
Focal complex [plasma membrane] (Danio rerio)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Danio rerio)
Talin:RIAM complex [plasma membrane] (Danio rerio)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Danio rerio)
apbb1ip [cytosol] (Danio rerio)
Dual mechanism MAPK inhibitors bind MAPKs (Danio rerio)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Danio rerio)
RAF/MAPK scaffolds [cytosol] (Danio rerio)
Focal Adhesion/Focal contacts [plasma membrane] (Danio rerio)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Danio rerio)
Focal complex [plasma membrane] (Danio rerio)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Danio rerio)
Talin:RIAM complex [plasma membrane] (Danio rerio)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Danio rerio)
apbb1ip [cytosol] (Danio rerio)
activated RAF:scaffold:p-2S MAP2K:MAPK:dual mechanism MAPK inhibitors [plasma membrane] (Danio rerio)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Danio rerio)
RAF/MAPK scaffolds [cytosol] (Danio rerio)
Focal Adhesion/Focal contacts [plasma membrane] (Danio rerio)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Danio rerio)
Focal complex [plasma membrane] (Danio rerio)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Danio rerio)
Talin:RIAM complex [plasma membrane] (Danio rerio)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Danio rerio)
apbb1ip [cytosol] (Danio rerio)
MAP2Ks phosphorylate MAPKs (Danio rerio)
activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Danio rerio)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Danio rerio)
RAF/MAPK scaffolds [cytosol] (Danio rerio)
Focal Adhesion/Focal contacts [plasma membrane] (Danio rerio)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Danio rerio)
Focal complex [plasma membrane] (Danio rerio)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Danio rerio)
Talin:RIAM complex [plasma membrane] (Danio rerio)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Danio rerio)
apbb1ip [cytosol] (Danio rerio)
activated RAF:scaffold:p-2S MAP2K:MAPK:single mechanism MAP2K inhibitors [plasma membrane] (Danio rerio)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Danio rerio)
RAF/MAPK scaffolds [cytosol] (Danio rerio)
Focal Adhesion/Focal contacts [plasma membrane] (Danio rerio)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Danio rerio)
Focal complex [plasma membrane] (Danio rerio)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Danio rerio)
Talin:RIAM complex [plasma membrane] (Danio rerio)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Danio rerio)
apbb1ip [cytosol] (Danio rerio)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Danio rerio)
RAF/MAPK scaffolds [cytosol] (Danio rerio)
Focal Adhesion/Focal contacts [plasma membrane] (Danio rerio)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Danio rerio)
Focal complex [plasma membrane] (Danio rerio)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Danio rerio)
Talin:RIAM complex [plasma membrane] (Danio rerio)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Danio rerio)
apbb1ip [cytosol] (Danio rerio)
activated RAF:scaffold:p-2S MAP2K:MAPK:dual mechanism MAPK inhibitors [plasma membrane] (Danio rerio)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Danio rerio)
RAF/MAPK scaffolds [cytosol] (Danio rerio)
Focal Adhesion/Focal contacts [plasma membrane] (Danio rerio)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Danio rerio)
Focal complex [plasma membrane] (Danio rerio)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Danio rerio)
Talin:RIAM complex [plasma membrane] (Danio rerio)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Danio rerio)
apbb1ip [cytosol] (Danio rerio)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Danio rerio)
RAF/MAPK scaffolds [cytosol] (Danio rerio)
Focal Adhesion/Focal contacts [plasma membrane] (Danio rerio)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Danio rerio)
Focal complex [plasma membrane] (Danio rerio)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Danio rerio)
Talin:RIAM complex [plasma membrane] (Danio rerio)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Danio rerio)
apbb1ip [cytosol] (Danio rerio)
RAF phosphorylates MAP2K dimer (Danio rerio)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Danio rerio)
RAF/MAPK scaffolds [cytosol] (Danio rerio)
Focal Adhesion/Focal contacts [plasma membrane] (Danio rerio)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Danio rerio)
Focal complex [plasma membrane] (Danio rerio)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Danio rerio)
Talin:RIAM complex [plasma membrane] (Danio rerio)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Danio rerio)
apbb1ip [cytosol] (Danio rerio)
activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Danio rerio)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Danio rerio)
RAF/MAPK scaffolds [cytosol] (Danio rerio)
Focal Adhesion/Focal contacts [plasma membrane] (Danio rerio)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Danio rerio)
Focal complex [plasma membrane] (Danio rerio)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Danio rerio)
Talin:RIAM complex [plasma membrane] (Danio rerio)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Danio rerio)
apbb1ip [cytosol] (Danio rerio)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Danio rerio)
RAF/MAPK scaffolds [cytosol] (Danio rerio)
Focal Adhesion/Focal contacts [plasma membrane] (Danio rerio)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Danio rerio)
Focal complex [plasma membrane] (Danio rerio)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Danio rerio)
Talin:RIAM complex [plasma membrane] (Danio rerio)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Danio rerio)
apbb1ip [cytosol] (Danio rerio)
Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks (Danio rerio)
activated RAF:scaffold:p-2S MAP2K:MAPK:single mechanism MAP2K inhibitors [plasma membrane] (Danio rerio)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Danio rerio)
RAF/MAPK scaffolds [cytosol] (Danio rerio)
Focal Adhesion/Focal contacts [plasma membrane] (Danio rerio)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Danio rerio)
Focal complex [plasma membrane] (Danio rerio)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Danio rerio)
Talin:RIAM complex [plasma membrane] (Danio rerio)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Danio rerio)
apbb1ip [cytosol] (Danio rerio)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Danio rerio)
RAF/MAPK scaffolds [cytosol] (Danio rerio)
Focal Adhesion/Focal contacts [plasma membrane] (Danio rerio)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Danio rerio)
Focal complex [plasma membrane] (Danio rerio)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Danio rerio)
Talin:RIAM complex [plasma membrane] (Danio rerio)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Danio rerio)
apbb1ip [cytosol] (Danio rerio)
Single mechanism MAPK inhibitors bind phosphorylated MAPK (Danio rerio)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Danio rerio)
RAF/MAPK scaffolds [cytosol] (Danio rerio)
Focal Adhesion/Focal contacts [plasma membrane] (Danio rerio)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Danio rerio)
Focal complex [plasma membrane] (Danio rerio)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Danio rerio)
Talin:RIAM complex [plasma membrane] (Danio rerio)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Danio rerio)
apbb1ip [cytosol] (Danio rerio)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK:single mechanism MAPK inhibitors [plasma membrane] (Danio rerio)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Danio rerio)
RAF/MAPK scaffolds [cytosol] (Danio rerio)
Focal Adhesion/Focal contacts [plasma membrane] (Danio rerio)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Danio rerio)
Focal complex [plasma membrane] (Danio rerio)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Danio rerio)
Talin:RIAM complex [plasma membrane] (Danio rerio)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Danio rerio)
apbb1ip [cytosol] (Danio rerio)
External Reference Information
External Reference
UniProt:Q6PFT9
Gene Names
apbb1ip
Reference Genes
BioGPS Gene:393607 apbb1ip
ENSEMBL:ENSDARG00000016505
KEGG:dre:393607 apbb1ip
Monarch:393607 apbb1ip
NCBI Gene:393607 apbb1ip
UCSC:Q6PFT9 apbb1ip
Participates
as an input of
Translocation of RIAM to plasma membrane (Danio rerio)
as a component of
Rap1-GTP:PIP2:RIAM [plasma membrane] (Danio rerio)
Inferred From
APBB1IP [cytosol]
(Homo sapiens)
Cross References
ZFIN
ZDB-GENE-040426-1318
PRO
Q6PFT9
© 2026
Reactome
This website requires cookies and the limited processing of your personal data in order to function. By using the site you are agreeing to this as outlined in our
Privacy Notice
.
I agree, dismiss this banner
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text
