Reactome | itgb5 [plasma membrane]

itgb5 [plasma membrane]

Stable Identifier

R-DRE-215948

Type

Protein [EntityWithAccessionedSequence]

Species

Danio rerio

Compartment

plasma membrane

Synonyms

ITGB5, Q1MSX8

Locations in the PathwayBrowser

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Immune System (Danio rerio)

- Adaptive Immune System (Danio rerio)
  - Class I MHC mediated antigen processing & presentation (Danio rerio)
    - Antigen processing-Cross presentation (Danio rerio)
      - Cross-presentation of particulate exogenous antigens (phagosomes) (Danio rerio)
        
        Engulfment of particulate antigen into phagocytic vesicle (Danio rerio)
        
        Particulate Ag:DC receptors [plasma membrane] (Danio rerio)
        
        DC receptors recognizing apoptotic cells [plasma membrane] (Danio rerio)
        
        Integrin alphaVbeta5 [plasma membrane] (Danio rerio)
        
        itgb5 [plasma membrane] (Danio rerio)
        
        Interaction of particulate antigens with dendritic cell receptors (Danio rerio)
        
        DC receptors recognizing apoptotic cells [plasma membrane] (Danio rerio)
        
        Integrin alphaVbeta5 [plasma membrane] (Danio rerio)
        
        itgb5 [plasma membrane] (Danio rerio)
        
        Particulate Ag:DC receptors [plasma membrane] (Danio rerio)
        
        DC receptors recognizing apoptotic cells [plasma membrane] (Danio rerio)
        
        Integrin alphaVbeta5 [plasma membrane] (Danio rerio)
        
        itgb5 [plasma membrane] (Danio rerio)

Signal Transduction (Danio rerio)

- Signaling by TGFB family members (Danio rerio)
  - Signaling by TGF-beta Receptor Complex (Danio rerio)
    - TGF-beta receptor signaling activates SMADs (Danio rerio)
      - Latent TGF-beta-3 binds integrins (Danio rerio)
        
        LAP1 binding-integrins [plasma membrane] (Danio rerio)
        
        Integrin alphaVbeta5 [plasma membrane] (Danio rerio)
        
        itgb5 [plasma membrane] (Danio rerio)
        
        TGF-beta-3:LAP3:LAP3-binding integrins [plasma membrane] (Danio rerio)
        
        LAP1 binding-integrins [plasma membrane] (Danio rerio)
        
        Integrin alphaVbeta5 [plasma membrane] (Danio rerio)
        
        itgb5 [plasma membrane] (Danio rerio)

External Reference Information

External Reference

UniProt:Q1MSX8

Gene Names

itgb5

Reference Genes

BioGPS Gene:563556 itgb5

ENSEMBL:ENSDARG00000012942

KEGG:dre:563556 itgb5

Monarch:563556 itgb5

NCBI Gene:563556 itgb5

UCSC:Q1MSX8 itgb5

Reference Transcript

RefSeq:NM_001082836.1 itgb5

Other Identifiers

13259699

13281120

563556

A_15_P131366

A_15_P161756

A_15_P433985

CJ013681

ENSDART00000017556_1

ENSDART00000017556_2

ENSDART00000080005

ENSDART00000101756

LOLS10393

XM_686922

Participates

as a component of

Integrin alphaVbeta5 [plasma membrane] (Danio rerio)

Other forms of this molecule

itgb5 [phagocytic vesicle]

Inferred From

ITGB5 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

NP_001076305.1

ENSEMBL

ENSDART00000180701, ENSDARP00000157296, ENSDARG00000114990

ZFIN

ZDB-GENE-030131-6022