Reactome | phospho-p-T180,Y182-MAPK11 [nucleoplasm]

phospho-p-T180,Y182-MAPK11 [nucleoplasm]

Stable Identifier

R-DRE-198741

Type

Protein [EntityWithAccessionedSequence]

Species

Danio rerio

Compartment

nucleoplasm

Synonyms

Q6IQ84

Locations in the PathwayBrowser

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Gene expression (Transcription) (Danio rerio)

- RNA Polymerase II Transcription (Danio rerio)
  - Generic Transcription Pathway (Danio rerio)
    - Transcriptional Regulation by TP53 (Danio rerio)
      - Regulation of TP53 Activity (Danio rerio)
        
        Regulation of TP53 Activity through Phosphorylation (Danio rerio)
        
        MAPKAPK5 phosphorylates TP53 (Danio rerio)
        
        phospho-p38 MAPK:p-T-182-MAPKAPK5 [nucleoplasm] (Danio rerio)
        
        p-p38 MAPK alpha/beta [nucleoplasm] (Danio rerio)
        
        phospho-p-T180,Y182-MAPK11 [nucleoplasm] (Danio rerio)

Signal Transduction (Danio rerio)

- Signaling by Receptor Tyrosine Kinases (Danio rerio)
  - Signaling by NTRKs (Danio rerio)
    - Signaling by NTRK1 (TRKA) (Danio rerio)
      - Nuclear Events (kinase and transcription factor activation) (Danio rerio)
        
        ERK/MAPK targets (Danio rerio)
        
        p38MAPK phosphorylates MSK1 (Danio rerio)
        
        p-p38 MAPK alpha/beta [nucleoplasm] (Danio rerio)
        
        phospho-p-T180,Y182-MAPK11 [nucleoplasm] (Danio rerio)

External Reference Information

External Reference

UniProt:Q6IQ84

Reference Genes

BioGPS Gene:415185

ENSEMBL:ENSDARG00000045836

KEGG:dre:415185

Monarch:415185

NCBI Gene:415185

UCSC:Q6IQ84

Reference Transcript

RefSeq:NM_001002095.1

Other Identifiers

13180098

415185

A_15_P119638

CJ013413

CJ014479

CUST_10022_PI428451953

CUST_2092_PI428451958

DRER04070

DRER45848

DRER48735

DRER48792

Dr.21717.1.A1_at

ENSDART00000032857

ENSDART00000032857_1

ENSDART00000032857_2

GO:0003824

GO:0004672

GO:0004707

GO:0005524

GO:0006468

GO:0016740

GO:0140096

GT_Spec_NM_001002095.1_236075

JP011542

JP011550

MADDr01005171

NM_001002095

OTTDART00000008889

Participates

as a member of

Other forms of this molecule

phospho-p-T180,Y182-MAPK11 [cytosol]

MAPK11 [cytosol]

MAPK11 [nucleoplasm]

Inferred From

p-T180,Y182-MAPK11 [nucleoplasm] (Homo sapiens)

Modified Residues

Name

O-phospho-L-threonine at 180 (in Homo sapiens)

Coordinate

180

PsiMod Name

O-phospho-L-threonine [MOD:00047]

PsiMod Definition

A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.

Name

O4'-phospho-L-tyrosine at 182 (in Homo sapiens)

Coordinate

182

PsiMod Name

O4'-phospho-L-tyrosine [MOD:00048]

PsiMod Definition

A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.

Cross References

ENSEMBL

ENSDARG00000045836, ENSDARP00000034350, ENSDART00000032857

ZFIN

ZDB-GENE-040625-75

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