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What is Reactome ?
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Team
Scientific Advisory Board
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Release Calendar
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Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
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Table of Contents
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fgf19 [extracellular region]
Stable Identifier
R-DRE-189888
Type
Protein [EntityWithAccessionedSequence]
Species
Danio rerio
Compartment
extracellular region
Synonyms
FGF19, A0A0R4IN60
Locations in the PathwayBrowser
Expand all
Signal Transduction (Danio rerio)
Intracellular signaling by second messengers (Danio rerio)
PIP3 activates AKT signaling (Danio rerio)
Negative regulation of the PI3K/AKT network (Danio rerio)
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling (Danio rerio)
PI3K phosphorylates PIP2 to PIP3 (Danio rerio)
Activator:PI3K [plasma membrane] (Danio rerio)
Activated FGFR4:p-FRS2:GRB2:GAB1:PI3K [plasma membrane] (Danio rerio)
Activated FGFR4:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Danio rerio)
Activated FGFR4:p-FRS2 [plasma membrane] (Danio rerio)
Activated FGFR4 [plasma membrane] (Danio rerio)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
Activated FGFR4 homodimer [plasma membrane] (Danio rerio)
FGFR4-binding FGFs [extracellular region] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
PI3K phosphorylates PIP2 to PIP3 (Danio rerio)
Activator:PI3K [plasma membrane] (Danio rerio)
Activated FGFR4:p-FRS2:GRB2:GAB1:PI3K [plasma membrane] (Danio rerio)
Activated FGFR4:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Danio rerio)
Activated FGFR4:p-FRS2 [plasma membrane] (Danio rerio)
Activated FGFR4 [plasma membrane] (Danio rerio)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
Activated FGFR4 homodimer [plasma membrane] (Danio rerio)
FGFR4-binding FGFs [extracellular region] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
MAPK family signaling cascades (Danio rerio)
MAPK1/MAPK3 signaling (Danio rerio)
RAF/MAP kinase cascade (Danio rerio)
RAS GEFs promote RAS nucleotide exchange (Danio rerio)
RAS GEFs [plasma membrane] (Danio rerio)
Activated FGFR4:p-FRS2:GRB2:SOS1 [plasma membrane] (Danio rerio)
Activated FGFR4:p-FRS [plasma membrane] (Danio rerio)
Activated FGFR4:p-FRS2 [plasma membrane] (Danio rerio)
Activated FGFR4 [plasma membrane] (Danio rerio)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
Activated FGFR4 homodimer [plasma membrane] (Danio rerio)
FGFR4-binding FGFs [extracellular region] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
Activated FGFR4:p-FRS3 [plasma membrane] (Danio rerio)
Activated FGFR4 [plasma membrane] (Danio rerio)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
Activated FGFR4 homodimer [plasma membrane] (Danio rerio)
FGFR4-binding FGFs [extracellular region] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
Activated FGFR4:pY-SHC1:GRB2:SOS1 [plasma membrane] (Danio rerio)
Activated FGFR4:pY-SHC1 [plasma membrane] (Danio rerio)
Activated FGFR4 [plasma membrane] (Danio rerio)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
Activated FGFR4 homodimer [plasma membrane] (Danio rerio)
FGFR4-binding FGFs [extracellular region] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
Signaling by Receptor Tyrosine Kinases (Danio rerio)
Signaling by FGFR (Danio rerio)
Signaling by FGFR4 (Danio rerio)
Downstream signaling of activated FGFR4 (Danio rerio)
FRS-mediated FGFR4 signaling (Danio rerio)
Activated FGFR4 binds FRS2 (Danio rerio)
Activated FGFR4 [plasma membrane] (Danio rerio)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
Activated FGFR4 homodimer [plasma membrane] (Danio rerio)
FGFR4-binding FGFs [extracellular region] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
Activated FGFR4:FRS2 [plasma membrane] (Danio rerio)
Activated FGFR4 [plasma membrane] (Danio rerio)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
Activated FGFR4 homodimer [plasma membrane] (Danio rerio)
FGFR4-binding FGFs [extracellular region] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
Activated FGFR4 binds FRS3 (Danio rerio)
Activated FGFR4 [plasma membrane] (Danio rerio)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
Activated FGFR4 homodimer [plasma membrane] (Danio rerio)
FGFR4-binding FGFs [extracellular region] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
Activated FGFR4:FRS3 [plasma membrane] (Danio rerio)
Activated FGFR4 [plasma membrane] (Danio rerio)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
Activated FGFR4 homodimer [plasma membrane] (Danio rerio)
FGFR4-binding FGFs [extracellular region] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
Activated FGFR4 phosphorylates FRS2 (Danio rerio)
Activated FGFR4:FRS2 [plasma membrane] (Danio rerio)
Activated FGFR4 [plasma membrane] (Danio rerio)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
Activated FGFR4 homodimer [plasma membrane] (Danio rerio)
FGFR4-binding FGFs [extracellular region] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
Activated FGFR4:p-8T-FRS2 [plasma membrane] (Danio rerio)
Activated FGFR4 [plasma membrane] (Danio rerio)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
Activated FGFR4 homodimer [plasma membrane] (Danio rerio)
FGFR4-binding FGFs [extracellular region] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
Activated FGFR4:p-FRS2 [plasma membrane] (Danio rerio)
Activated FGFR4 [plasma membrane] (Danio rerio)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
Activated FGFR4 homodimer [plasma membrane] (Danio rerio)
FGFR4-binding FGFs [extracellular region] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
Activated FGFR4 phosphorylates FRS3 (Danio rerio)
Activated FGFR4:FRS3 [plasma membrane] (Danio rerio)
Activated FGFR4 [plasma membrane] (Danio rerio)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
Activated FGFR4 homodimer [plasma membrane] (Danio rerio)
FGFR4-binding FGFs [extracellular region] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
Activated FGFR4:p-FRS3 [plasma membrane] (Danio rerio)
Activated FGFR4 [plasma membrane] (Danio rerio)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
Activated FGFR4 homodimer [plasma membrane] (Danio rerio)
FGFR4-binding FGFs [extracellular region] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
Activated FGFR4 phosphorylates PPTN11 (Danio rerio)
Activated FGFR4:p-FRS:PTPN11 [plasma membrane] (Danio rerio)
Activated FGFR4:p-FRS [plasma membrane] (Danio rerio)
Activated FGFR4:p-FRS2 [plasma membrane] (Danio rerio)
Activated FGFR4 [plasma membrane] (Danio rerio)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
Activated FGFR4 homodimer [plasma membrane] (Danio rerio)
FGFR4-binding FGFs [extracellular region] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
Activated FGFR4:p-FRS3 [plasma membrane] (Danio rerio)
Activated FGFR4 [plasma membrane] (Danio rerio)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
Activated FGFR4 homodimer [plasma membrane] (Danio rerio)
FGFR4-binding FGFs [extracellular region] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
Activated FGFR4:p-FRS:p-PTPN11 [plasma membrane] (Danio rerio)
Activated FGFR4:p-FRS [plasma membrane] (Danio rerio)
Activated FGFR4:p-FRS2 [plasma membrane] (Danio rerio)
Activated FGFR4 [plasma membrane] (Danio rerio)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
Activated FGFR4 homodimer [plasma membrane] (Danio rerio)
FGFR4-binding FGFs [extracellular region] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
Activated FGFR4:p-FRS3 [plasma membrane] (Danio rerio)
Activated FGFR4 [plasma membrane] (Danio rerio)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
Activated FGFR4 homodimer [plasma membrane] (Danio rerio)
FGFR4-binding FGFs [extracellular region] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
Activated FGFR4:p-FRS binds GRB2:SOS1 (Danio rerio)
Activated FGFR4:p-FRS [plasma membrane] (Danio rerio)
Activated FGFR4:p-FRS2 [plasma membrane] (Danio rerio)
Activated FGFR4 [plasma membrane] (Danio rerio)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
Activated FGFR4 homodimer [plasma membrane] (Danio rerio)
FGFR4-binding FGFs [extracellular region] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
Activated FGFR4:p-FRS3 [plasma membrane] (Danio rerio)
Activated FGFR4 [plasma membrane] (Danio rerio)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
Activated FGFR4 homodimer [plasma membrane] (Danio rerio)
FGFR4-binding FGFs [extracellular region] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
Activated FGFR4:p-FRS2:GRB2:SOS1 [plasma membrane] (Danio rerio)
Activated FGFR4:p-FRS [plasma membrane] (Danio rerio)
Activated FGFR4:p-FRS2 [plasma membrane] (Danio rerio)
Activated FGFR4 [plasma membrane] (Danio rerio)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
Activated FGFR4 homodimer [plasma membrane] (Danio rerio)
FGFR4-binding FGFs [extracellular region] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
Activated FGFR4:p-FRS3 [plasma membrane] (Danio rerio)
Activated FGFR4 [plasma membrane] (Danio rerio)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
Activated FGFR4 homodimer [plasma membrane] (Danio rerio)
FGFR4-binding FGFs [extracellular region] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Danio rerio)
Activated FGFR4:p-FRS2:GRB2:SOS1 [plasma membrane] (Danio rerio)
Activated FGFR4:p-FRS [plasma membrane] (Danio rerio)
Activated FGFR4:p-FRS2 [plasma membrane] (Danio rerio)
Activated FGFR4 [plasma membrane] (Danio rerio)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
Activated FGFR4 homodimer [plasma membrane] (Danio rerio)
FGFR4-binding FGFs [extracellular region] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
Activated FGFR4:p-FRS3 [plasma membrane] (Danio rerio)
Activated FGFR4 [plasma membrane] (Danio rerio)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
Activated FGFR4 homodimer [plasma membrane] (Danio rerio)
FGFR4-binding FGFs [extracellular region] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
Activated FGFR4:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Danio rerio)
Activated FGFR4:p-FRS:p-PTPN11 [plasma membrane] (Danio rerio)
Activated FGFR4:p-FRS [plasma membrane] (Danio rerio)
Activated FGFR4:p-FRS2 [plasma membrane] (Danio rerio)
Activated FGFR4 [plasma membrane] (Danio rerio)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
Activated FGFR4 homodimer [plasma membrane] (Danio rerio)
FGFR4-binding FGFs [extracellular region] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
Activated FGFR4:p-FRS3 [plasma membrane] (Danio rerio)
Activated FGFR4 [plasma membrane] (Danio rerio)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
Activated FGFR4 homodimer [plasma membrane] (Danio rerio)
FGFR4-binding FGFs [extracellular region] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
PI-3K cascade:FGFR4 (Danio rerio)
Activated FGFR4:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA (Danio rerio)
Activated FGFR4:p-FRS2:GRB2:GAB1:PI3K [plasma membrane] (Danio rerio)
Activated FGFR4:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Danio rerio)
Activated FGFR4:p-FRS2 [plasma membrane] (Danio rerio)
Activated FGFR4 [plasma membrane] (Danio rerio)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
Activated FGFR4 homodimer [plasma membrane] (Danio rerio)
FGFR4-binding FGFs [extracellular region] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
Activated FGFR4:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Danio rerio)
Activated FGFR4:p-FRS2 [plasma membrane] (Danio rerio)
Activated FGFR4 [plasma membrane] (Danio rerio)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
Activated FGFR4 homodimer [plasma membrane] (Danio rerio)
FGFR4-binding FGFs [extracellular region] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
Activated FGFR4:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1binds PIK3CA (Danio rerio)
Activated FGFR4:p-FRS2:p-PTPN11:GRB2:GAB1:PI3K [plasma membrane] (Danio rerio)
Activated FGFR4:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] (Danio rerio)
Activated FGFR4:p-FRS2:p-PTPN11 [plasma membrane] (Danio rerio)
Activated FGFR4:p-FRS2 [plasma membrane] (Danio rerio)
Activated FGFR4 [plasma membrane] (Danio rerio)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
Activated FGFR4 homodimer [plasma membrane] (Danio rerio)
FGFR4-binding FGFs [extracellular region] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
Activated FGFR4:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] (Danio rerio)
Activated FGFR4:p-FRS2:p-PTPN11 [plasma membrane] (Danio rerio)
Activated FGFR4:p-FRS2 [plasma membrane] (Danio rerio)
Activated FGFR4 [plasma membrane] (Danio rerio)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
Activated FGFR4 homodimer [plasma membrane] (Danio rerio)
FGFR4-binding FGFs [extracellular region] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
FGFR4- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 (Danio rerio)
Activated FGFR4:p-FRS2:p-PTPN11:GRB2:GAB1:PI3K [plasma membrane] (Danio rerio)
Activated FGFR4:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] (Danio rerio)
Activated FGFR4:p-FRS2:p-PTPN11 [plasma membrane] (Danio rerio)
Activated FGFR4:p-FRS2 [plasma membrane] (Danio rerio)
Activated FGFR4 [plasma membrane] (Danio rerio)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
Activated FGFR4 homodimer [plasma membrane] (Danio rerio)
FGFR4-binding FGFs [extracellular region] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
FGFR4-associated PI3K phosphorylates PIP2 to PIP3 (Danio rerio)
Activated FGFR4:p-FRS2:GRB2:GAB1:PI3K [plasma membrane] (Danio rerio)
Activated FGFR4:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Danio rerio)
Activated FGFR4:p-FRS2 [plasma membrane] (Danio rerio)
Activated FGFR4 [plasma membrane] (Danio rerio)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
Activated FGFR4 homodimer [plasma membrane] (Danio rerio)
FGFR4-binding FGFs [extracellular region] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
Phospholipase C-mediated cascade; FGFR4 (Danio rerio)
Activated FGFR4 binds PLCG1 (Danio rerio)
Activated FGFR4 [plasma membrane] (Danio rerio)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
Activated FGFR4 homodimer [plasma membrane] (Danio rerio)
FGFR4-binding FGFs [extracellular region] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
activated FGFR4:PLCG1 [plasma membrane] (Danio rerio)
Activated FGFR4 [plasma membrane] (Danio rerio)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
Activated FGFR4 homodimer [plasma membrane] (Danio rerio)
FGFR4-binding FGFs [extracellular region] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
Activated FGFR4 phosphorylates PLCG1 (Danio rerio)
activated FGFR4:PLCG1 [plasma membrane] (Danio rerio)
Activated FGFR4 [plasma membrane] (Danio rerio)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
Activated FGFR4 homodimer [plasma membrane] (Danio rerio)
FGFR4-binding FGFs [extracellular region] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
activated FGFR4:p-4Y-PLCG1 [plasma membrane] (Danio rerio)
Activated FGFR4 [plasma membrane] (Danio rerio)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
Activated FGFR4 homodimer [plasma membrane] (Danio rerio)
FGFR4-binding FGFs [extracellular region] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
p-4Y-PLCG1 dissociates from activated FGFR4 (Danio rerio)
Activated FGFR4 [plasma membrane] (Danio rerio)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
Activated FGFR4 homodimer [plasma membrane] (Danio rerio)
FGFR4-binding FGFs [extracellular region] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
activated FGFR4:p-4Y-PLCG1 [plasma membrane] (Danio rerio)
Activated FGFR4 [plasma membrane] (Danio rerio)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
Activated FGFR4 homodimer [plasma membrane] (Danio rerio)
FGFR4-binding FGFs [extracellular region] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
SHC-mediated cascade:FGFR4 (Danio rerio)
Activated FGFR4 phosphorylates SHC1 (Danio rerio)
Activated FGFR4:SHC1 [plasma membrane] (Danio rerio)
Activated FGFR4 [plasma membrane] (Danio rerio)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
Activated FGFR4 homodimer [plasma membrane] (Danio rerio)
FGFR4-binding FGFs [extracellular region] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
Activated FGFR4:pY-SHC1 [plasma membrane] (Danio rerio)
Activated FGFR4 [plasma membrane] (Danio rerio)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
Activated FGFR4 homodimer [plasma membrane] (Danio rerio)
FGFR4-binding FGFs [extracellular region] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
Activated FGFR4:p-SHC1 binds GRB2:SOS1 (Danio rerio)
Activated FGFR4:pY-SHC1 [plasma membrane] (Danio rerio)
Activated FGFR4 [plasma membrane] (Danio rerio)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
Activated FGFR4 homodimer [plasma membrane] (Danio rerio)
FGFR4-binding FGFs [extracellular region] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
Activated FGFR4:pY-SHC1:GRB2:SOS1 [plasma membrane] (Danio rerio)
Activated FGFR4:pY-SHC1 [plasma membrane] (Danio rerio)
Activated FGFR4 [plasma membrane] (Danio rerio)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
Activated FGFR4 homodimer [plasma membrane] (Danio rerio)
FGFR4-binding FGFs [extracellular region] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
Activated FGFR4:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Danio rerio)
Activated FGFR4:pY-SHC1:GRB2:SOS1 [plasma membrane] (Danio rerio)
Activated FGFR4:pY-SHC1 [plasma membrane] (Danio rerio)
Activated FGFR4 [plasma membrane] (Danio rerio)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
Activated FGFR4 homodimer [plasma membrane] (Danio rerio)
FGFR4-binding FGFs [extracellular region] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
FGFR4 ligand binding and activation (Danio rerio)
Autocatalytic phosphorylation of FGFR4 (Danio rerio)
Activated FGFR4 homodimer [plasma membrane] (Danio rerio)
FGFR4-binding FGFs [extracellular region] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
FGFR4 homodimer bound to FGF [plasma membrane] (Danio rerio)
FGFR4-binding FGFs [extracellular region] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
FGFR4 binds to FGF (Danio rerio)
FGFR4 homodimer bound to FGF [plasma membrane] (Danio rerio)
FGFR4-binding FGFs [extracellular region] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
FGFR4-binding FGFs [extracellular region] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
betaKlotho-mediated ligand binding (Danio rerio)
Autocatalytic phosphorylation of BetaKlotho-bound FGFR4 (Danio rerio)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
FGFR4:HS:KLB:FGF19 [plasma membrane] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
FGFR4 binds HS:KLB:FGF19 (Danio rerio)
FGFR4:HS:KLB:FGF19 [plasma membrane] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
Negative regulation of FGFR4 signaling (Danio rerio)
Activated ERK1/2 threonine-phosphorylates FGFR4-associated FRS2 (Danio rerio)
Activated FGFR4:FRS2 [plasma membrane] (Danio rerio)
Activated FGFR4 [plasma membrane] (Danio rerio)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
Activated FGFR4 homodimer [plasma membrane] (Danio rerio)
FGFR4-binding FGFs [extracellular region] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
Activated FGFR4:p-8T-FRS2 [plasma membrane] (Danio rerio)
Activated FGFR4 [plasma membrane] (Danio rerio)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
Activated FGFR4 homodimer [plasma membrane] (Danio rerio)
FGFR4-binding FGFs [extracellular region] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
CBL ubiquitinates FRS2 and FGFR4 (Danio rerio)
Activated FGFR4:p-FRS2:p-PPTN11:p-CBL:GRB2 [plasma membrane] (Danio rerio)
Activated FGFR4:p-FRS2:p-PTPN11 [plasma membrane] (Danio rerio)
Activated FGFR4:p-FRS2 [plasma membrane] (Danio rerio)
Activated FGFR4 [plasma membrane] (Danio rerio)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
Activated FGFR4 homodimer [plasma membrane] (Danio rerio)
FGFR4-binding FGFs [extracellular region] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
Ub-Activated FGFR4 complex:Ub-p-FRS2 [plasma membrane] (Danio rerio)
Activated FGFR4:p-FRS2:p-PPTN11:p-CBL:GRB2 [plasma membrane] (Danio rerio)
Activated FGFR4:p-FRS2:p-PTPN11 [plasma membrane] (Danio rerio)
Activated FGFR4:p-FRS2 [plasma membrane] (Danio rerio)
Activated FGFR4 [plasma membrane] (Danio rerio)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
Activated FGFR4 homodimer [plasma membrane] (Danio rerio)
FGFR4-binding FGFs [extracellular region] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
p-CBL:GRB2 binds p-FRS2:activated FGFR4 (Danio rerio)
Activated FGFR4:p-FRS2:p-PPTN11:p-CBL:GRB2 [plasma membrane] (Danio rerio)
Activated FGFR4:p-FRS2:p-PTPN11 [plasma membrane] (Danio rerio)
Activated FGFR4:p-FRS2 [plasma membrane] (Danio rerio)
Activated FGFR4 [plasma membrane] (Danio rerio)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
Activated FGFR4 homodimer [plasma membrane] (Danio rerio)
FGFR4-binding FGFs [extracellular region] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
Activated FGFR4:p-FRS2:p-PTPN11 [plasma membrane] (Danio rerio)
Activated FGFR4:p-FRS2 [plasma membrane] (Danio rerio)
Activated FGFR4 [plasma membrane] (Danio rerio)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
Activated FGFR4 homodimer [plasma membrane] (Danio rerio)
FGFR4-binding FGFs [extracellular region] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
Signaling by Insulin receptor (Danio rerio)
Insulin receptor signalling cascade (Danio rerio)
IRS-mediated signalling (Danio rerio)
PI3K Cascade (Danio rerio)
PI3K-containing complexes phosphorylate PIP2 to PIP3 (Danio rerio)
PI3K-containing complexes [cytosol] (Danio rerio)
Activated FGFR bound to PI3K [cytosol] (Danio rerio)
GRB2 and GAB1 bound to activated FGFR and FRS2-alpha [plasma membrane] (Danio rerio)
Activated FGFR:p-FRS2:p-PTPN11 [plasma membrane] (Danio rerio)
Activated FGFR:p-FRS2 [plasma membrane] (Danio rerio)
Activated FGFR [plasma membrane] (Danio rerio)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
Activated FGFR4 homodimer [plasma membrane] (Danio rerio)
FGFR4-binding FGFs [extracellular region] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) (Danio rerio)
IGF1R signaling cascade (Danio rerio)
IRS-related events triggered by IGF1R (Danio rerio)
IRS-mediated signalling (Danio rerio)
PI3K Cascade (Danio rerio)
PI3K-containing complexes phosphorylate PIP2 to PIP3 (Danio rerio)
PI3K-containing complexes [cytosol] (Danio rerio)
Activated FGFR bound to PI3K [cytosol] (Danio rerio)
GRB2 and GAB1 bound to activated FGFR and FRS2-alpha [plasma membrane] (Danio rerio)
Activated FGFR:p-FRS2:p-PTPN11 [plasma membrane] (Danio rerio)
Activated FGFR:p-FRS2 [plasma membrane] (Danio rerio)
Activated FGFR [plasma membrane] (Danio rerio)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
Activated FGFR4 homodimer [plasma membrane] (Danio rerio)
FGFR4-binding FGFs [extracellular region] (Danio rerio)
fgf19 [extracellular region] (Danio rerio)
External Reference Information
External Reference
UniProt:A0A0R4IN60
Gene Names
fgf19
Reference Genes
BioGPS Gene:368245 fgf19
ENSEMBL:ENSDARG00000098663
Monarch:368245 fgf19
NCBI Gene:368245 fgf19
UCSC:A0A0R4IN60 fgf19
Reference Transcript
RefSeq:NM_001309359.1 fgf19
Other Identifiers
13240228
368245
A_15_P246411
CJ012833
CJ012900
CJ013023
CJ013086
CUST_20653_PI428451953
CUST_20654_PI428451953
CUST_9541_PI428451958
DRER06377
DRER12184
DRER31167
ENSDART00000051866
ENSDART00000051866_1
ENSDART00000051866_2
ENSDART00000082018
ENSDART00000112078
ENSDART00000113035
GO:0005104
GO:0005576
GO:0008083
GO:0008543
GO:0048018
GO:0098772
GT_Spec_XM_005166591.1_31461
GT_Xhyb_NM_001012246.1_110512
MADDr01008118
NM_001012246
OTTDART00000025348
XM_693935
Participates
as an input of
FGFR4 binds HS:KLB:FGF19 (Danio rerio)
as a component of
FGFR4:HS:KLB:FGF19 [plasma membrane] (Danio rerio)
Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] (Danio rerio)
as a member of
FGFR4-binding FGFs [extracellular region] (Danio rerio)
Other forms of this molecule
fgf19 [extracellular region]
Inferred From
FGF19 [extracellular region]
(Homo sapiens)
Cross References
RefSeq
NP_001296288.1
ENSEMBL
ENSDARG00000098663
,
ENSDART00000171864
,
ENSDARP00000135780
ZFIN
ZDB-GENE-030729-32
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