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smad7 [cytosol]
Stable Identifier
R-DRE-173478
Type
Protein [EntityWithAccessionedSequence]
Species
Danio rerio
Compartment
cytosol
Synonyms
SMAD7, Q6NZT3
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Danio rerio)
Post-translational protein modification (Danio rerio)
Deubiquitination (Danio rerio)
Ub-specific processing proteases (Danio rerio)
USP15 deubiquitinates SMAD1,SMAD2,SMAD3, SMAD7:SMURF,KEAP1 (Danio rerio)
USP15:SMAD1,SMAD2,SMAD3,KEAP1,SMAD7:SMURF2:TGFBR1 [cytosol] (Danio rerio)
SMAD1,SMAD2,SMAD3,KEAP1,SMAD7:SMURF2:TGFBR1 [cytosol] (Danio rerio)
SMAD7:SMURF2:TGFBR1 [plasma membrane] (Danio rerio)
SMAD7:SMURF2 [cytosol] (Danio rerio)
smad7 [cytosol] (Danio rerio)
USP15:Ub-SMAD1,Ub-SMAD2,Ub-SMAD3,,Ub-KEAP1,SMAD7:SMURF2:Ub-TGFBR1 [cytosol] (Danio rerio)
Ub-SMAD1,Ub-SMAD2,Ub-SMAD3,,Ub-KEAP1,SMAD7:SMURF2:Ub-TGFBR1 [cytosol] (Danio rerio)
SMAD7:SMURF2:Ub-TGFBR1 [plasma membrane] (Danio rerio)
smad7 [cytosol] (Danio rerio)
Signal Transduction (Danio rerio)
Signaling by TGFB family members (Danio rerio)
Signaling by BMP (Danio rerio)
I-Smad binds to type I receptor, preventing Smad1/5/8 from being activated (Danio rerio)
BMP:p-BMPR:I-SMAD:SMURF [plasma membrane] (Danio rerio)
I-SMAD:SMURF [cytosol] (Danio rerio)
I-SMAD [cytosol] (Danio rerio)
smad7 [cytosol] (Danio rerio)
I-SMAD:SMURF [cytosol] (Danio rerio)
I-SMAD [cytosol] (Danio rerio)
smad7 [cytosol] (Danio rerio)
I-Smad competes with Co-Smad for R-Smad1/5/8 (Danio rerio)
I-SMAD [cytosol] (Danio rerio)
smad7 [cytosol] (Danio rerio)
I-SMAD:p-2S-SMAD1/5/8 [cytosol] (Danio rerio)
I-SMAD [cytosol] (Danio rerio)
smad7 [cytosol] (Danio rerio)
I-Smad competes with R-Smad1/5/8 for type I receptor (Danio rerio)
BMP2:BMP type II receptor:Phospho-BMP type I receptor:I-SMAD [plasma membrane] (Danio rerio)
I-SMAD [cytosol] (Danio rerio)
smad7 [cytosol] (Danio rerio)
I-SMAD [cytosol] (Danio rerio)
smad7 [cytosol] (Danio rerio)
Signaling by TGF-beta Receptor Complex (Danio rerio)
TGF-beta receptor signaling activates SMADs (Danio rerio)
Downregulation of TGF-beta receptor signaling (Danio rerio)
BAMBI interferes with the interaction of type I receptor with type II receptor (Danio rerio)
TGFB1: TGFBR2: p-TGFBR1: BAMBI: SMAD7 [plasma membrane] (Danio rerio)
smad7 [cytosol] (Danio rerio)
smad7 [cytosol] (Danio rerio)
Degradation of TGF-beta receptor complex (Danio rerio)
TGFB1:TGFBR2:Ub-p-TGFBR1:Ub-SMAD7 [plasma membrane] (Danio rerio)
TGFB1: p-TGFBR: I-SMAD7 [plasma membrane] (Danio rerio)
smad7 [cytosol] (Danio rerio)
I-SMAD competes with SMAD2/3 for type I receptor (TGFBR1) (Danio rerio)
TGFB1: p-TGFBR: I-SMAD7 [plasma membrane] (Danio rerio)
smad7 [cytosol] (Danio rerio)
smad7 [cytosol] (Danio rerio)
STRAP stabilizes interaction of activated TGF-beta receptor complex with SMAD7 (Danio rerio)
TGFB1: p-TGFBR: STRAP: SMAD7 [plasma membrane] (Danio rerio)
smad7 [cytosol] (Danio rerio)
smad7 [cytosol] (Danio rerio)
External Reference Information
External Reference
UniProt:Q6NZT3
Gene Names
smad7
Reference Genes
BioGPS Gene:326282 smad7
ENSEMBL:ENSDARG00000016858
KEGG Gene (Danio rerio):326282 smad7
Monarch:326282 smad7
NCBI Gene:326282 smad7
Reference Transcript
RefSeq:NM_175082.3 smad7
Participates
as a component of
SMAD7:SMURF2:Ub-TGFBR1 [plasma membrane] (Danio rerio)
TGFB1: TGFBR2: p-TGFBR1: BAMBI: SMAD7 [plasma membrane] (Danio rerio)
SMAD7:SMURF2 [cytosol] (Danio rerio)
TGFB1: p-TGFBR: STRAP: SMAD7 [plasma membrane] (Danio rerio)
TGFB1: p-TGFBR: I-SMAD7 [plasma membrane] (Danio rerio)
as a member of
I-SMAD [cytosol] (Danio rerio)
as an input of
BAMBI interferes with the interaction of type I receptor with type II receptor (Danio rerio)
STRAP stabilizes interaction of activated TGF-beta receptor complex with SMAD7 (Danio rerio)
I-SMAD competes with SMAD2/3 for type I receptor (TGFBR1) (Danio rerio)
Other forms of this molecule
smad7 [nucleoplasm]
Inferred From
SMAD7 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_778257.2
ZFIN
ZDB-GENE-030128-3
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