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frs2b [plasma membrane]
Stable Identifier
R-DRE-170963
Type
Protein [EntityWithAccessionedSequence]
Species
Danio rerio
Compartment
plasma membrane
Synonyms
FRS2, F1Q5H9
Locations in the PathwayBrowser
Expand all
Developmental Biology (Danio rerio)
Nervous system development (Danio rerio)
Axon guidance (Danio rerio)
RET signaling (Danio rerio)
2x p-5Y-RET:GDNF:GFRA complexes bind FRS2 (Danio rerio)
2x p-5Y-RET:GDNF:GFRA complexes:FRS2 [plasma membrane] (Danio rerio)
frs2b [plasma membrane] (Danio rerio)
frs2b [plasma membrane] (Danio rerio)
Signal Transduction (Danio rerio)
Signaling by Receptor Tyrosine Kinases (Danio rerio)
Signaling by FGFR (Danio rerio)
Signaling by FGFR1 (Danio rerio)
Downstream signaling of activated FGFR1 (Danio rerio)
FRS-mediated FGFR1 signaling (Danio rerio)
Activated FGFR1 binds FRS2 (Danio rerio)
Activated FGFR1:FRS2 [plasma membrane] (Danio rerio)
frs2b [plasma membrane] (Danio rerio)
frs2b [plasma membrane] (Danio rerio)
Activated FGFR1 phosphorylates FRS2 (Danio rerio)
Activated FGFR1:FRS2 [plasma membrane] (Danio rerio)
frs2b [plasma membrane] (Danio rerio)
Negative regulation of FGFR1 signaling (Danio rerio)
Activated ERK1/2 threonine-phosphorylates FGFR1-associated FRS2 (Danio rerio)
Activated FGFR1:FRS2 [plasma membrane] (Danio rerio)
frs2b [plasma membrane] (Danio rerio)
Signaling by FGFR2 (Danio rerio)
Downstream signaling of activated FGFR2 (Danio rerio)
FRS-mediated FGFR2 signaling (Danio rerio)
Activated FGFR2 binds FRS2 (Danio rerio)
Activated FGFR2:FRS2 [plasma membrane] (Danio rerio)
frs2b [plasma membrane] (Danio rerio)
frs2b [plasma membrane] (Danio rerio)
Activated FGFR2 phosphorylates FRS2 (Danio rerio)
Activated FGFR2:FRS2 [plasma membrane] (Danio rerio)
frs2b [plasma membrane] (Danio rerio)
Negative regulation of FGFR2 signaling (Danio rerio)
Activated ERK1/2 threonine-phosphorylates FGFR2-associated FRS2 (Danio rerio)
Activated FGFR2:FRS2 [plasma membrane] (Danio rerio)
frs2b [plasma membrane] (Danio rerio)
Signaling by FGFR3 (Danio rerio)
Downstream signaling of activated FGFR3 (Danio rerio)
FRS-mediated FGFR3 signaling (Danio rerio)
Activated FGFR3 binds FRS2 (Danio rerio)
Activated FGFR3:FRS2 [plasma membrane] (Danio rerio)
frs2b [plasma membrane] (Danio rerio)
frs2b [plasma membrane] (Danio rerio)
Activated FGFR3 phosphorylates FRS2 (Danio rerio)
Activated FGFR3:FRS2 [plasma membrane] (Danio rerio)
frs2b [plasma membrane] (Danio rerio)
Negative regulation of FGFR3 signaling (Danio rerio)
Activated ERK1/2 threonine-phosphorylates FGFR3-associated FRS2 (Danio rerio)
Activated FGFR3:FRS2 [plasma membrane] (Danio rerio)
frs2b [plasma membrane] (Danio rerio)
Signaling by FGFR4 (Danio rerio)
Downstream signaling of activated FGFR4 (Danio rerio)
FRS-mediated FGFR4 signaling (Danio rerio)
Activated FGFR4 binds FRS2 (Danio rerio)
Activated FGFR4:FRS2 [plasma membrane] (Danio rerio)
frs2b [plasma membrane] (Danio rerio)
frs2b [plasma membrane] (Danio rerio)
Activated FGFR4 phosphorylates FRS2 (Danio rerio)
Activated FGFR4:FRS2 [plasma membrane] (Danio rerio)
frs2b [plasma membrane] (Danio rerio)
Negative regulation of FGFR4 signaling (Danio rerio)
Activated ERK1/2 threonine-phosphorylates FGFR4-associated FRS2 (Danio rerio)
Activated FGFR4:FRS2 [plasma membrane] (Danio rerio)
frs2b [plasma membrane] (Danio rerio)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Danio rerio)
Signaling by Rho GTPases (Danio rerio)
RHO GTPase cycle (Danio rerio)
RND1 GTPase cycle (Danio rerio)
RND1 binds effectors (Danio rerio)
RND1 effectors [cytosol] (Danio rerio)
frs2b [plasma membrane] (Danio rerio)
RND1:GTP:RND1 effectors [plasma membrane] (Danio rerio)
RND1 effectors [cytosol] (Danio rerio)
frs2b [plasma membrane] (Danio rerio)
RND2 GTPase cycle (Danio rerio)
RND2 binds effectors (Danio rerio)
RND2 effectors [cytosol] (Danio rerio)
frs2b [plasma membrane] (Danio rerio)
RND2:GTP:RND2 effectors [plasma membrane] (Danio rerio)
RND2 effectors [cytosol] (Danio rerio)
frs2b [plasma membrane] (Danio rerio)
External Reference Information
External Reference
UniProt:F1Q5H9
Gene Names
frs2b
Reference Genes
BioGPS Gene:436931 frs2b
CTD Gene:436931 frs2b
ENSEMBL:ENSDARG00000037353
KEGG:dre:436931 frs2b
Monarch:436931 frs2b
NCBI Gene:436931 frs2b
UCSC:F1Q5H9 frs2b
Reference Transcript
RefSeq:NM_001002658.2 frs2b
Other Identifiers
13163103
436931
A_15_P101699
A_15_P162891
A_15_P628351
CJ013142
CUST_5467_PI428451953
CUST_5821_PI428451958
DRER36780
Dr.5313.1.A1_at
ENSDART00000054349
ENSDART00000054349_1
ENSDART00000054349_2
GT_Xhyb_NM_001002658.1_224375
GT_Xhyb_XM_005163169.1_404305
LOLS10417
MADDr01009510
NM_001002658
OTTDART00000028765
ZV700S00005574
Participates
as a member of
RND2 effectors [cytosol] (Danio rerio)
RND1 effectors [cytosol] (Danio rerio)
as an input of
2x p-5Y-RET:GDNF:GFRA complexes bind FRS2 (Danio rerio)
Activated FGFR4 binds FRS2 (Danio rerio)
Activated FGFR1 binds FRS2 (Danio rerio)
Activated FGFR3 binds FRS2 (Danio rerio)
Activated FGFR2 binds FRS2 (Danio rerio)
as a component of
2x p-5Y-RET:GDNF:GFRA complexes:FRS2 [plasma membrane] (Danio rerio)
Activated FGFR4:FRS2 [plasma membrane] (Danio rerio)
Activated FGFR1:FRS2 [plasma membrane] (Danio rerio)
Activated FGFR3:FRS2 [plasma membrane] (Danio rerio)
Activated FGFR2:FRS2 [plasma membrane] (Danio rerio)
Other forms of this molecule
frs2b [cytosol]
phospho-frs2b [cytosol]
phospho-frs2b [plasma membrane]
phospho-frs2b [plasma membrane]
Inferred From
FRS2 [plasma membrane]
(Homo sapiens)
Cross References
RefSeq
NP_001002658.2
ENSEMBL
ENSDART00000137665
,
ENSDARG00000037353
,
ENSDARP00000114775
ZFIN
ZDB-GENE-040718-406
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