Reactome | hist2h3ca1 [nucleoplasm]

hist2h3ca1 [nucleoplasm]

Stable Identifier

R-DRE-1214170

Type

Protein [EntityWithAccessionedSequence]

Species

Danio rerio

Compartment

nucleoplasm

Synonyms

Me2K5-HIST1H3A, A0A140LG23

Locations in the PathwayBrowser

Expand all

Cell Cycle (Danio rerio)

- Cell Cycle, Mitotic (Danio rerio)
  - M Phase (Danio rerio)
    - Mitotic Prophase (Danio rerio)
      - Condensation of Prophase Chromosomes (Danio rerio)
        
        CDK1 phosphorylates PHF8 (Danio rerio)
        
        Nucleosome with H3K4me2/3:H4K20me1 [nucleoplasm] (Danio rerio)
        
        H3K4me2/3 [nucleoplasm] (Danio rerio)
        
        H3K4me2 [nucleoplasm] (Danio rerio)
        
        hist2h3ca1 [nucleoplasm] (Danio rerio)
        
        PHF8:Nucleosome with H3K4me2/3:H4K20me1 [nucleoplasm] (Danio rerio)
        
        Nucleosome with H3K4me2/3:H4K20me1 [nucleoplasm] (Danio rerio)
        
        H3K4me2/3 [nucleoplasm] (Danio rerio)
        
        H3K4me2 [nucleoplasm] (Danio rerio)
        
        hist2h3ca1 [nucleoplasm] (Danio rerio)
        
        CDK1 phosphorylates condensin II subunit NCAPD3 (Danio rerio)
        
        Condensin II:Nucleosome with H4K20me1 [nucleoplasm] (Danio rerio)
        
        Nucleosome with H3K4me2/3:H4K20me1 [nucleoplasm] (Danio rerio)
        
        H3K4me2/3 [nucleoplasm] (Danio rerio)
        
        H3K4me2 [nucleoplasm] (Danio rerio)
        
        hist2h3ca1 [nucleoplasm] (Danio rerio)
        
        Phosphorylated Condensin II:Nucleosome [nucleoplasm] (Danio rerio)
        
        Nucleosome with H3K4me2/3:H4K20me1 [nucleoplasm] (Danio rerio)
        
        H3K4me2/3 [nucleoplasm] (Danio rerio)
        
        H3K4me2 [nucleoplasm] (Danio rerio)
        
        hist2h3ca1 [nucleoplasm] (Danio rerio)
        
        Condensin II complex binds H4K20me1-containing nucleosomes (Danio rerio)
        
        Condensin II:Nucleosome with H4K20me1 [nucleoplasm] (Danio rerio)
        
        Nucleosome with H3K4me2/3:H4K20me1 [nucleoplasm] (Danio rerio)
        
        H3K4me2/3 [nucleoplasm] (Danio rerio)
        
        H3K4me2 [nucleoplasm] (Danio rerio)
        
        hist2h3ca1 [nucleoplasm] (Danio rerio)
        
        Nucleosome with H3K4me2/3:H4K20me1 [nucleoplasm] (Danio rerio)
        
        H3K4me2/3 [nucleoplasm] (Danio rerio)
        
        H3K4me2 [nucleoplasm] (Danio rerio)
        
        hist2h3ca1 [nucleoplasm] (Danio rerio)
        
        PHF8 demethylates histone H4K20me1 (Danio rerio)
        
        PHF8:Nucleosome with H3K4me2/3 [nucleoplasm] (Danio rerio)
        
        Nucleosome with H3K4me2/3 [nucleoplasm] (Danio rerio)
        
        H3K4me2/3 [nucleoplasm] (Danio rerio)
        
        H3K4me2 [nucleoplasm] (Danio rerio)
        
        hist2h3ca1 [nucleoplasm] (Danio rerio)
        
        PHF8:Nucleosome with H3K4me2/3:H4K20me1 [nucleoplasm] (Danio rerio)
        
        Nucleosome with H3K4me2/3:H4K20me1 [nucleoplasm] (Danio rerio)
        
        H3K4me2/3 [nucleoplasm] (Danio rerio)
        
        H3K4me2 [nucleoplasm] (Danio rerio)
        
        hist2h3ca1 [nucleoplasm] (Danio rerio)
        
        PLK1 binds phosphorylated condensin II complex (Danio rerio)
        
        Phosphorylated Condensin II:Nucleosome [nucleoplasm] (Danio rerio)
        
        Nucleosome with H3K4me2/3:H4K20me1 [nucleoplasm] (Danio rerio)
        
        H3K4me2/3 [nucleoplasm] (Danio rerio)
        
        H3K4me2 [nucleoplasm] (Danio rerio)
        
        hist2h3ca1 [nucleoplasm] (Danio rerio)
        
        p-T210-PLK1:Phosphorylated Condensin II:Nucleosome [nucleoplasm] (Danio rerio)
        
        Nucleosome with H3K4me2/3:H4K20me1 [nucleoplasm] (Danio rerio)
        
        H3K4me2/3 [nucleoplasm] (Danio rerio)
        
        H3K4me2 [nucleoplasm] (Danio rerio)
        
        hist2h3ca1 [nucleoplasm] (Danio rerio)
        
        PLK1 hyperphosphorylates Condensin II complex (Danio rerio)
        
        Hyperphosphorylated Condensin II:Nucleosome [nucleoplasm] (Danio rerio)
        
        Nucleosome with H3K4me2/3:H4K20me1 [nucleoplasm] (Danio rerio)
        
        H3K4me2/3 [nucleoplasm] (Danio rerio)
        
        H3K4me2 [nucleoplasm] (Danio rerio)
        
        hist2h3ca1 [nucleoplasm] (Danio rerio)
        
        p-T210-PLK1:Phosphorylated Condensin II:Nucleosome [nucleoplasm] (Danio rerio)
        
        Nucleosome with H3K4me2/3:H4K20me1 [nucleoplasm] (Danio rerio)
        
        H3K4me2/3 [nucleoplasm] (Danio rerio)
        
        H3K4me2 [nucleoplasm] (Danio rerio)
        
        hist2h3ca1 [nucleoplasm] (Danio rerio)
        
        SETD8 monomethylates histone H4 (Danio rerio)
        
        PHF8:Nucleosome with H3K4me2/3 [nucleoplasm] (Danio rerio)
        
        Nucleosome with H3K4me2/3 [nucleoplasm] (Danio rerio)
        
        H3K4me2/3 [nucleoplasm] (Danio rerio)
        
        H3K4me2 [nucleoplasm] (Danio rerio)
        
        hist2h3ca1 [nucleoplasm] (Danio rerio)
        
        PHF8:Nucleosome with H3K4me2/3:H4K20me1 [nucleoplasm] (Danio rerio)
        
        Nucleosome with H3K4me2/3:H4K20me1 [nucleoplasm] (Danio rerio)
        
        H3K4me2/3 [nucleoplasm] (Danio rerio)
        
        H3K4me2 [nucleoplasm] (Danio rerio)
        
        hist2h3ca1 [nucleoplasm] (Danio rerio)

Signal Transduction (Danio rerio)

- Signaling by Nuclear Receptors (Danio rerio)
  - ESR-mediated signaling (Danio rerio)
    - Estrogen-dependent gene expression (Danio rerio)
      - FOXA1 and GATA3 bind to CCND1 promoter (Danio rerio)
        
        CCND1 gene:H3K4me2 nucleosome:FOXA1:GATA3 [nucleoplasm] (Danio rerio)
        
        Nucleosome with H3K4me2 [nucleoplasm] (Danio rerio)
        
        hist2h3ca1 [nucleoplasm] (Danio rerio)
        
        CCND1 gene:H3K4me2 nucleosome:YY1:HDAC1 [nucleoplasm] (Danio rerio)
        
        Nucleosome with H3K4me2 [nucleoplasm] (Danio rerio)
        
        hist2h3ca1 [nucleoplasm] (Danio rerio)

External Reference Information

External Reference

UniProt:A0A140LG23

Gene Names

hist2h3ca1

Reference Genes

BioGPS Gene:368227 hist2h3ca1

ENSEMBL:ENSDARG00000105508

KEGG:dre:368227 hist2h3ca1

Monarch:368227 hist2h3ca1

NCBI Gene:368227 hist2h3ca1

UCSC:A0A140LG23 hist2h3ca1

Reference Transcript

Other Identifiers

13285896

368227

A_15_P199611

ENSDART00000097807

ENSDART00000097807_x_1

ENSDART00000097807_x_2

GO:0000786

GO:0003677

GO:0005198

GO:0030527

GO:0046982

XM_677616

Participates

as a candidate of

H3K4me2 [nucleoplasm] (Danio rerio)

as a component of

Nucleosome with H3K4me2 [nucleoplasm] (Danio rerio)

Other forms of this molecule

hist2h3ca1 [nucleoplasm]

hist2h3ca1 [cytosol]

hist2h3ca1 [nucleoplasm]

hist2h3ca1 [extracellular region]

hist2h3ca1 [nucleoplasm]

phospho-hist2h3ca1 [nucleoplasm]

hist2h3ca1 [nucleoplasm]

Inferred From

Me2K5-HIST3H3 [nucleoplasm] (Homo sapiens)

Histone H3 (H3K4me2) [nucleoplasm] (Homo sapiens)

Me2K5-HIST1H3A [nucleoplasm] (Homo sapiens)

Modified Residues

Name

N6,N6-dimethyl-L-lysine at 5 (in Homo sapiens)

Coordinate

PsiMod Name

N6,N6-dimethyl-L-lysine [MOD:00084]

PsiMod Definition

A protein modification that effectively converts an L-lysine residue to N6,N6-dimethyl-L-lysine.

Cross References

RefSeq

XP_009301168.1, NP_001353364.1

ENSEMBL

ENSDART00000173105, ENSDARP00000142201, ENSDARG00000105508

ZFIN

ZDB-GENE-030722-8