Reactome | maca [nucleoplasm]

maca [nucleoplasm]

Stable Identifier

R-DME-9770135-2

Type

Protein [EntityWithAccessionedSequence]

Species

Drosophila melanogaster

Compartment

nucleoplasm

Synonyms

SRSF8, Q9VF55

Locations in the PathwayBrowser

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Metabolism of RNA (Drosophila melanogaster)

- Processing of Capped Intron-Containing Pre-mRNA (Drosophila melanogaster)
  - Formation of pre-mRNPs (Drosophila melanogaster)
    - Alternative Splicing Factors [nucleoplasm] (Drosophila melanogaster)
      - nonshuttling SRSFs [nucleoplasm] (Drosophila melanogaster)
        
        Homologues of SRSF8 [nucleoplasm] (Drosophila melanogaster)
        
        maca [nucleoplasm] (Drosophila melanogaster)
    - capped, methylated pre-mRNP:CBC complex [nucleoplasm] (Drosophila melanogaster)
      - Alternative Splicing Factors [nucleoplasm] (Drosophila melanogaster)
        
        nonshuttling SRSFs [nucleoplasm] (Drosophila melanogaster)
        
        Homologues of SRSF8 [nucleoplasm] (Drosophila melanogaster)
        
        maca [nucleoplasm] (Drosophila melanogaster)
  - mRNA 3'-end processing (Drosophila melanogaster)
    - mRNA Polyadenylation (Drosophila melanogaster)
      - Core CPA complex binds capped pre-mRNA (Drosophila melanogaster)
        
        Core CPA complex:Spliceosomal A complex (uncleaved pre-mRNA) [nucleoplasm] (Drosophila melanogaster)
        
        Spliceosomal A complex (capped, methylated pre-mRNA) [nucleoplasm] (Drosophila melanogaster)
        
        capped, methylated pre-mRNP:CBC complex [nucleoplasm] (Drosophila melanogaster)
        
        Alternative Splicing Factors [nucleoplasm] (Drosophila melanogaster)
        
        nonshuttling SRSFs [nucleoplasm] (Drosophila melanogaster)
        
        Homologues of SRSF8 [nucleoplasm] (Drosophila melanogaster)
        
        maca [nucleoplasm] (Drosophila melanogaster)
        
        Spliceosomal A complex (capped, methylated pre-mRNA) [nucleoplasm] (Drosophila melanogaster)
        
        capped, methylated pre-mRNP:CBC complex [nucleoplasm] (Drosophila melanogaster)
        
        Alternative Splicing Factors [nucleoplasm] (Drosophila melanogaster)
        
        nonshuttling SRSFs [nucleoplasm] (Drosophila melanogaster)
        
        Homologues of SRSF8 [nucleoplasm] (Drosophila melanogaster)
        
        maca [nucleoplasm] (Drosophila melanogaster)
      - PABPN1-stimulated PAPOL synthesizes polyA tail at distal 3'UTR PAS (Drosophila melanogaster)
        
        Ub-K63-CPA:PABPN1:Spliceosomal A complex (pre-mRNA polyadenylated at distal 3'UTR PAS) [nucleoplasm] (Drosophila melanogaster)
        
        Spliceosomal A complex (pre-mRNA polyadenylated at distal 3'UTR PAS) [nucleoplasm] (Drosophila melanogaster)
        
        capped, methylated pre-mRNP:CBC complex (pre-mRNA polyadenylated at distal 3'UTR PAS) [nucleoplasm] (Drosophila melanogaster)
        
        Alternative Splicing Factors [nucleoplasm] (Drosophila melanogaster)
        
        nonshuttling SRSFs [nucleoplasm] (Drosophila melanogaster)
        
        Homologues of SRSF8 [nucleoplasm] (Drosophila melanogaster)
        
        maca [nucleoplasm] (Drosophila melanogaster)
        
        Ub-K63-CPA:Spliceosomal A complex (pre-mRNA cleaved at distal 3'UTR PAS) [nucleoplasm] (Drosophila melanogaster)
        
        Spliceosomal A complex (pre-mRNA cleaved at distal 3'UTR PAS) [nucleoplasm] (Drosophila melanogaster)
        
        capped, methylated pre-mRNP:CBC complex (pre-mRNA cleaved at distal 3'UTR PAS) [nucleoplasm] (Drosophila melanogaster)
        
        Alternative Splicing Factors [nucleoplasm] (Drosophila melanogaster)
        
        nonshuttling SRSFs [nucleoplasm] (Drosophila melanogaster)
        
        Homologues of SRSF8 [nucleoplasm] (Drosophila melanogaster)
        
        maca [nucleoplasm] (Drosophila melanogaster)
      - PABPN1-stimulated PAPOL synthesizes polyA tail at intronic PAS (Drosophila melanogaster)
        
        Ub-K63-CPA:PABPN1:Spliceosomal A complex (pre-mRNA polyadenylated at intronic PAS) [nucleoplasm] (Drosophila melanogaster)
        
        Spliceosomal A complex (pre-mRNA polyadenylated at intronic PAS) [nucleoplasm] (Drosophila melanogaster)
        
        capped, methylated pre-mRNP:CBC complex (pre-mRNA polyadenylated at intronic PAS) [nucleoplasm] (Drosophila melanogaster)
        
        Alternative Splicing Factors [nucleoplasm] (Drosophila melanogaster)
        
        nonshuttling SRSFs [nucleoplasm] (Drosophila melanogaster)
        
        Homologues of SRSF8 [nucleoplasm] (Drosophila melanogaster)
        
        maca [nucleoplasm] (Drosophila melanogaster)
        
        Ub-K63-CPA:Spliceosomal A complex (pre-mRNA cleaved at intronic PAS) [nucleoplasm] (Drosophila melanogaster)
        
        Spliceosomal A complex (pre-mRNA cleaved at intronal PAS) [nucleoplasm] (Drosophila melanogaster)
        
        capped, methylated pre-mRNP:CBC complex (pre-mRNA cleaved at intronic PAS) [nucleoplasm] (Drosophila melanogaster)
        
        Alternative Splicing Factors [nucleoplasm] (Drosophila melanogaster)
        
        nonshuttling SRSFs [nucleoplasm] (Drosophila melanogaster)
        
        Homologues of SRSF8 [nucleoplasm] (Drosophila melanogaster)
        
        maca [nucleoplasm] (Drosophila melanogaster)
      - PABPN1-stimulated PAPOL synthesizes polyA tail at proximal 3'UTR PAS (Drosophila melanogaster)
        
        Ub-K63-CPA:PABPN1:Spliceosomal A complex (pre-mRNA polyadenylated at proximal 3'UTR PAS) [nucleoplasm] (Drosophila melanogaster)
        
        Spliceosomal A complex (pre-mRNA polyadenylated at proximal 3'UTR PAS) [nucleoplasm] (Drosophila melanogaster)
        
        capped, methylated pre-mRNP:CBC complex (pre-mRNA polyadenylated at proximal 3'UTR PAS) [nucleoplasm] (Drosophila melanogaster)
        
        Alternative Splicing Factors [nucleoplasm] (Drosophila melanogaster)
        
        nonshuttling SRSFs [nucleoplasm] (Drosophila melanogaster)
        
        Homologues of SRSF8 [nucleoplasm] (Drosophila melanogaster)
        
        maca [nucleoplasm] (Drosophila melanogaster)
        
        Ub-K63-CPA:Spliceosomal A complex (pre-mRNA cleaved at proximal 3'UTR PAS) [nucleoplasm] (Drosophila melanogaster)
        
        Spliceosomal A complex (pre-mRNA cleaved at proximal 3'UTR PAS) [nucleoplasm] (Drosophila melanogaster)
        
        capped, methylated pre-mRNP:CBC complex (pre-mRNA cleaved at proximal 3'UTR PAS) [nucleoplasm] (Drosophila melanogaster)
        
        Alternative Splicing Factors [nucleoplasm] (Drosophila melanogaster)
        
        nonshuttling SRSFs [nucleoplasm] (Drosophila melanogaster)
        
        Homologues of SRSF8 [nucleoplasm] (Drosophila melanogaster)
        
        maca [nucleoplasm] (Drosophila melanogaster)
      - PP1 dephosphorylates RNA Pol II (Drosophila melanogaster)
        
        CPA:Spliceosomal A complex (uncleaved pre-mRNA) [nucleoplasm] (Drosophila melanogaster)
        
        Spliceosomal A complex (capped, methylated pre-mRNA) [nucleoplasm] (Drosophila melanogaster)
        
        capped, methylated pre-mRNP:CBC complex [nucleoplasm] (Drosophila melanogaster)
        
        Alternative Splicing Factors [nucleoplasm] (Drosophila melanogaster)
        
        nonshuttling SRSFs [nucleoplasm] (Drosophila melanogaster)
        
        Homologues of SRSF8 [nucleoplasm] (Drosophila melanogaster)
        
        maca [nucleoplasm] (Drosophila melanogaster)
        
        CPA:Spliceosomal A complex (uncleaved pre-mRNA, RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Drosophila melanogaster)
        
        Spliceosomal A complex (RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Drosophila melanogaster)
        
        capped, methylated pre-mRNP:CBC complex (RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Drosophila melanogaster)
        
        Alternative Splicing Factors [nucleoplasm] (Drosophila melanogaster)
        
        nonshuttling SRSFs [nucleoplasm] (Drosophila melanogaster)
        
        Homologues of SRSF8 [nucleoplasm] (Drosophila melanogaster)
        
        maca [nucleoplasm] (Drosophila melanogaster)
      - RBBP6 activates CPSF complex (Drosophila melanogaster)
        
        CPA:Spliceosomal A complex (uncleaved pre-mRNA, RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Drosophila melanogaster)
        
        Spliceosomal A complex (RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Drosophila melanogaster)
        
        capped, methylated pre-mRNP:CBC complex (RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Drosophila melanogaster)
        
        Alternative Splicing Factors [nucleoplasm] (Drosophila melanogaster)
        
        nonshuttling SRSFs [nucleoplasm] (Drosophila melanogaster)
        
        Homologues of SRSF8 [nucleoplasm] (Drosophila melanogaster)
        
        maca [nucleoplasm] (Drosophila melanogaster)
        
        Ub-K63-CPA:Spliceosomal A complex (uncleaved pre-mRNA, RNA Pol II Ser2 dephosphorylated) [nucleoplasm] (Drosophila melanogaster)
        
        Spliceosomal A complex (RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Drosophila melanogaster)
        
        capped, methylated pre-mRNP:CBC complex (RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Drosophila melanogaster)
        
        Alternative Splicing Factors [nucleoplasm] (Drosophila melanogaster)
        
        nonshuttling SRSFs [nucleoplasm] (Drosophila melanogaster)
        
        Homologues of SRSF8 [nucleoplasm] (Drosophila melanogaster)
        
        maca [nucleoplasm] (Drosophila melanogaster)
  - mRNA Splicing (Drosophila melanogaster)
    - mRNA Splicing - Major Pathway (Drosophila melanogaster)
      - Formation of the Spliceosomal B* complex (Drosophila melanogaster)
        
        Spliceosomal B* complex [nucleoplasm] (Drosophila melanogaster)
        
        capped, methylated, polyadenylated pre-mRNP:CBC complex [nucleoplasm] (Drosophila melanogaster)
        
        Alternative Splicing Factors [nucleoplasm] (Drosophila melanogaster)
        
        nonshuttling SRSFs [nucleoplasm] (Drosophila melanogaster)
        
        Homologues of SRSF8 [nucleoplasm] (Drosophila melanogaster)
        
        maca [nucleoplasm] (Drosophila melanogaster)
        
        Spliceosomal Bact complex [nucleoplasm] (Drosophila melanogaster)
        
        capped, methylated, polyadenylated pre-mRNP:CBC complex [nucleoplasm] (Drosophila melanogaster)
        
        Alternative Splicing Factors [nucleoplasm] (Drosophila melanogaster)
        
        nonshuttling SRSFs [nucleoplasm] (Drosophila melanogaster)
        
        Homologues of SRSF8 [nucleoplasm] (Drosophila melanogaster)
        
        maca [nucleoplasm] (Drosophila melanogaster)
      - Formation of the Spliceosomal C complex containing intron lariat (Drosophila melanogaster)
        
        Spliceosomal B* complex [nucleoplasm] (Drosophila melanogaster)
        
        capped, methylated, polyadenylated pre-mRNP:CBC complex [nucleoplasm] (Drosophila melanogaster)
        
        Alternative Splicing Factors [nucleoplasm] (Drosophila melanogaster)
        
        nonshuttling SRSFs [nucleoplasm] (Drosophila melanogaster)
        
        Homologues of SRSF8 [nucleoplasm] (Drosophila melanogaster)
        
        maca [nucleoplasm] (Drosophila melanogaster)
        
        Spliceosomal C complex [nucleoplasm] (Drosophila melanogaster)
        
        Alternative Splicing Factors [nucleoplasm] (Drosophila melanogaster)
        
        nonshuttling SRSFs [nucleoplasm] (Drosophila melanogaster)
        
        Homologues of SRSF8 [nucleoplasm] (Drosophila melanogaster)
        
        maca [nucleoplasm] (Drosophila melanogaster)
      - Formation of the Spliceosomal C* complex (Drosophila melanogaster)
        
        Spliceosomal C complex [nucleoplasm] (Drosophila melanogaster)
        
        Alternative Splicing Factors [nucleoplasm] (Drosophila melanogaster)
        
        nonshuttling SRSFs [nucleoplasm] (Drosophila melanogaster)
        
        Homologues of SRSF8 [nucleoplasm] (Drosophila melanogaster)
        
        maca [nucleoplasm] (Drosophila melanogaster)
        
        Spliceosomal C* complex [nucleoplasm] (Drosophila melanogaster)
        
        Alternative Splicing Factors [nucleoplasm] (Drosophila melanogaster)
        
        nonshuttling SRSFs [nucleoplasm] (Drosophila melanogaster)
        
        Homologues of SRSF8 [nucleoplasm] (Drosophila melanogaster)
        
        maca [nucleoplasm] (Drosophila melanogaster)
      - Formation of the Spliceosomal P complex and exon ligation (Drosophila melanogaster)
        
        Spliceosomal C* complex [nucleoplasm] (Drosophila melanogaster)
        
        Alternative Splicing Factors [nucleoplasm] (Drosophila melanogaster)
        
        nonshuttling SRSFs [nucleoplasm] (Drosophila melanogaster)
        
        Homologues of SRSF8 [nucleoplasm] (Drosophila melanogaster)
        
        maca [nucleoplasm] (Drosophila melanogaster)
        
        Spliceosomal P complex [nucleoplasm] (Drosophila melanogaster)
        
        spliced mRNA:EJC:CBC complex:Alternative splicing factor [nucleoplasm] (Drosophila melanogaster)
        
        Alternative Splicing Factors [nucleoplasm] (Drosophila melanogaster)
        
        nonshuttling SRSFs [nucleoplasm] (Drosophila melanogaster)
        
        Homologues of SRSF8 [nucleoplasm] (Drosophila melanogaster)
        
        maca [nucleoplasm] (Drosophila melanogaster)

External Reference Information

External Reference

UniProt:Q9VF55

Gene Names

maca

Reference Genes

BioGPS Gene:41892 maca

ENSEMBL:FBgn0038345

FlyBase:FBgn0038345

KEGG:dme:Dmel_CG5213 maca

Monarch:41892 maca

NCBI Gene:41892 maca

UCSC:Q9VF55 maca

Reference Transcript

RefSeq:NM_142216.3 maca

Other Identifiers

149963_at

1627725_at

41892

GO:0000381

GO:0000398

GO:0000791

GO:0003676

GO:0003723

GO:0003729

GO:0005515

GO:0005634

GO:0005737

GO:0009967

GO:0010628

GO:0010629

GO:0016071

GO:0016607

GO:1990904

Participates

as a member of

Homologues of SRSF8 [nucleoplasm] (Drosophila melanogaster)

Inferred From

SRSF8 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_650473.1

FlyBase

FBgn0038345

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