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Mkrn1 [cytosol]
Stable Identifier
R-DME-976042
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
cytosol
Synonyms
MKRN1, Q9VP20
Locations in the PathwayBrowser
Expand all
Immune System (Drosophila melanogaster)
Adaptive Immune System (Drosophila melanogaster)
Class I MHC mediated antigen processing & presentation (Drosophila melanogaster)
Antigen processing: Ubiquitination & Proteasome degradation (Drosophila melanogaster)
Interaction of E3 with substrate and E2-Ub complex (Drosophila melanogaster)
Ag-substrate:E3:E2:Ub [cytosol] (Drosophila melanogaster)
E3 ligases in proteasomal degradation [cytosol] (Drosophila melanogaster)
Mkrn1 [cytosol] (Drosophila melanogaster)
E3 ligases in proteasomal degradation [cytosol] (Drosophila melanogaster)
Mkrn1 [cytosol] (Drosophila melanogaster)
Polyubiquitination of substrate (Drosophila melanogaster)
E3 ligases in proteasomal degradation [cytosol] (Drosophila melanogaster)
Mkrn1 [cytosol] (Drosophila melanogaster)
E3:K48-polyubiquitinated substrate [cytosol] (Drosophila melanogaster)
E3 ligases in proteasomal degradation [cytosol] (Drosophila melanogaster)
Mkrn1 [cytosol] (Drosophila melanogaster)
E3:Ub:substrate [cytosol] (Drosophila melanogaster)
E3 ligases in proteasomal degradation [cytosol] (Drosophila melanogaster)
Mkrn1 [cytosol] (Drosophila melanogaster)
Release of E3 from polyubiquitinated substrate (Drosophila melanogaster)
E3 ligases in proteasomal degradation [cytosol] (Drosophila melanogaster)
Mkrn1 [cytosol] (Drosophila melanogaster)
E3:K48-polyubiquitinated substrate [cytosol] (Drosophila melanogaster)
E3 ligases in proteasomal degradation [cytosol] (Drosophila melanogaster)
Mkrn1 [cytosol] (Drosophila melanogaster)
Transfer of Ub from E2 to substrate and release of E2 (Drosophila melanogaster)
Ag-substrate:E3:E2:Ub [cytosol] (Drosophila melanogaster)
E3 ligases in proteasomal degradation [cytosol] (Drosophila melanogaster)
Mkrn1 [cytosol] (Drosophila melanogaster)
E3 ligases in proteasomal degradation [cytosol] (Drosophila melanogaster)
Mkrn1 [cytosol] (Drosophila melanogaster)
E3:Ub:substrate [cytosol] (Drosophila melanogaster)
E3 ligases in proteasomal degradation [cytosol] (Drosophila melanogaster)
Mkrn1 [cytosol] (Drosophila melanogaster)
Signal Transduction (Drosophila melanogaster)
Intracellular signaling by second messengers (Drosophila melanogaster)
PIP3 activates AKT signaling (Drosophila melanogaster)
AKT phosphorylates targets in the cytosol (Drosophila melanogaster)
AKT phosphorylates MKRN1 (Drosophila melanogaster)
Mkrn1 [cytosol] (Drosophila melanogaster)
PTEN Regulation (Drosophila melanogaster)
Regulation of PTEN stability and activity (Drosophila melanogaster)
AKT phosphorylates MKRN1 (Drosophila melanogaster)
Mkrn1 [cytosol] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:Q9VP20
Gene Names
Mkrn1
Reference Genes
BioGPS Gene:44131 Mkrn1
ENSEMBL:FBgn0029152
FlyBase:FBgn0029152
KEGG:dme:Dmel_CG7184 Mkrn1
Monarch:44131 Mkrn1
NCBI Gene:44131 Mkrn1
UCSC:Q9VP20 Mkrn1
Other Identifiers
149186_at
1630989_a_at
1636847_s_at
44131
GO:0000209
GO:0003730
GO:0003824
GO:0004842
GO:0005575
GO:0005634
GO:0008270
GO:0008595
GO:0016567
GO:0016740
GO:0043186
GO:0043226
GO:0045495
GO:0046012
GO:0046628
GO:0046872
GO:0060255
GO:0061630
GO:0140096
GO:1905881
GO:1990904
Participates
as an input of
AKT phosphorylates MKRN1 (Drosophila melanogaster)
as a candidate of
E3 ligases in proteasomal degradation [cytosol] (Drosophila melanogaster)
Other forms of this molecule
phospho-Mkrn1 [cytosol]
Inferred From
MKRN1 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_001246867.1
,
NP_524704.1
,
NP_730653.1
FlyBase
FBgn0029152
Interactors (4)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P23757 POXM
0.488
2
UniProt:Q29QK1 Q29QK1
0.488
2
UniProt:P48598-2 EIF4E1
0.488
2
UniProt:P25867 eff
4
EFF [cytosol]
(R-DME-205773)
eff [cytosol]
(R-DME-8864160)
eff [nucleoplasm]
(R-DME-174197)
eff [cytosol]
(R-DME-174236)
0.488
2
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