Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
phospho-p-S218,T356,S360,S377,T570,T730-RPS6KA2 [cytosol]
Stable Identifier
R-DME-9619869
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
cytosol
Synonyms
Q9VR61
Locations in the PathwayBrowser
Expand all
Neuronal System (Drosophila melanogaster)
Transmission across Chemical Synapses (Drosophila melanogaster)
Neurotransmitter receptors and postsynaptic signal transmission (Drosophila melanogaster)
Activation of NMDA receptors and postsynaptic events (Drosophila melanogaster)
Post NMDA receptor activation events (Drosophila melanogaster)
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling (Drosophila melanogaster)
RSK activation (Drosophila melanogaster)
p-S363,S380,T573 RS6K translocates to the nucleus (Drosophila melanogaster)
p-S221,T359.S363,S380,T573,T732-RSK [cytosol] (Drosophila melanogaster)
phospho-p-S218,T356,S360,S377,T570,T730-RPS6KA2 [cytosol] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:Q9VR61
Reference Genes
BioGPS Gene:33139
ENSEMBL:FBgn0262866
FlyBase:FBgn0262866
KEGG:dme:Dmel_CG17596
Monarch:33139
NCBI Gene:33139
UCSC:Q9VR61
Reference Transcript
RefSeq:NM_078713.3
RefSeq:NM_001272850.1
Other Identifiers
141623_at
1640019_at
33139
GO:0000166
GO:0000287
GO:0003824
GO:0004672
GO:0004674
GO:0004711
GO:0005515
GO:0005524
GO:0005654
GO:0005737
GO:0005829
GO:0006468
GO:0007474
GO:0007528
GO:0008306
GO:0008340
GO:0016301
GO:0016740
GO:0031594
GO:0034330
GO:0035106
GO:0035556
GO:0038202
GO:0042308
GO:0042683
GO:0043204
GO:0045475
GO:0046533
GO:0050877
GO:0050941
GO:0051019
GO:0070373
GO:0090101
GO:0098793
GO:0106310
GO:0140096
GO:1904396
Participates
as a member of
p-S221,T359.S363,S380,T573,T732-RSK [cytosol] (Drosophila melanogaster)
Other forms of this molecule
phospho-p-S232,T368,S372,S389,T581,S742-RPS6KA6 [nucleoplasm]
phospho-p-4S,T359,T573-RPS6KA1 [nucleoplasm]
phospho-p-S218,T356,S360,S377,T570,T730-RPS6KA2 [nucleoplasm]
phospho-p-S227,T365,S369,S386,T577,T737-RPS6KA3 [nucleoplasm]
phospho-p-S232,T368,S372,S389,T581,S742-RPS6KA6 [cytosol]
phospho-p-S227,T365,S369,S386,T577,T737-RPS6KA3 [cytosol]
phospho-p-S221,T459,S363,S380,T573,S732-RPS6KA1 [cytosol]
phospho-p-4S,T231,T365-RPS6KA3 [nucleoplasm]
phospho-p-4S,T356,T570-RPS6KA2 [nucleoplasm]
RPS6KA2 [nucleoplasm]
RPS6KA1 [nucleoplasm]
RPS6KA3 [nucleoplasm]
Inferred From
p-S218,T356,S360,S377,T570,T730-RPS6KA2 [cytosol]
(Homo sapiens)
Modified Residues
Name
O-phospho-L-serine at 218 (in Homo sapiens)
Coordinate
218
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-threonine at 356 (in Homo sapiens)
Coordinate
356
PsiMod Name
O-phospho-L-threonine [MOD:00047]
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Name
O-phospho-L-serine at 360 (in Homo sapiens)
Coordinate
360
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 377 (in Homo sapiens)
Coordinate
377
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-threonine at 570 (in Homo sapiens)
Coordinate
570
PsiMod Name
O-phospho-L-threonine [MOD:00047]
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Name
O-phospho-L-threonine at 730 (in Homo sapiens)
Coordinate
730
PsiMod Name
O-phospho-L-threonine [MOD:00047]
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Cross References
RefSeq
NP_523437.2
,
NP_001259779.1
FlyBase
FBgn0262866
© 2026
Reactome
This website requires cookies and the limited processing of your personal data in order to function. By using the site you are agreeing to this as outlined in our
Privacy Notice
.
I agree, dismiss this banner
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text