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phospho-p-4S,T359,T573-RPS6KA1 [nucleoplasm]
Stable Identifier
R-DME-199829
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
nucleoplasm
Synonyms
Q9VR61
Locations in the PathwayBrowser
Expand all
Cellular responses to stimuli (Drosophila melanogaster)
Cellular responses to stress (Drosophila melanogaster)
Cellular Senescence (Drosophila melanogaster)
Senescence-Associated Secretory Phenotype (SASP) (Drosophila melanogaster)
ERK1/2/5 activate RSK1/2/3 (Drosophila melanogaster)
Phospho-Ribosomal protein S6 kinase [nucleoplasm] (Drosophila melanogaster)
phospho-p-4S,T359,T573-RPS6KA1 [nucleoplasm] (Drosophila melanogaster)
Developmental Biology (Drosophila melanogaster)
MITF-M-regulated melanocyte development (Drosophila melanogaster)
Transcriptional and post-translational regulation of MITF-M expression and activity (Drosophila melanogaster)
RPS6KA1-dependent phosphorylation of MITF-M (Drosophila melanogaster)
phospho-p-4S,T359,T573-RPS6KA1 [nucleoplasm] (Drosophila melanogaster)
Immune System (Drosophila melanogaster)
Cytokine Signaling in Immune system (Drosophila melanogaster)
Signaling by Interleukins (Drosophila melanogaster)
Interleukin-17 signaling (Drosophila melanogaster)
MAP kinase activation (Drosophila melanogaster)
MAPK targets/ Nuclear events mediated by MAP kinases (Drosophila melanogaster)
CREB phosphorylation (Drosophila melanogaster)
RSK1/2/3 phosphorylates CREB at Serine 119 (Drosophila melanogaster)
Phospho-Ribosomal protein S6 kinase [nucleoplasm] (Drosophila melanogaster)
phospho-p-4S,T359,T573-RPS6KA1 [nucleoplasm] (Drosophila melanogaster)
ERK/MAPK targets (Drosophila melanogaster)
ERK1/2/5 activate RSK1/2/3 (Drosophila melanogaster)
Phospho-Ribosomal protein S6 kinase [nucleoplasm] (Drosophila melanogaster)
phospho-p-4S,T359,T573-RPS6KA1 [nucleoplasm] (Drosophila melanogaster)
Innate Immune System (Drosophila melanogaster)
Toll-like Receptor Cascades (Drosophila melanogaster)
Toll Like Receptor 10 (TLR10) Cascade (Drosophila melanogaster)
MyD88 cascade initiated on plasma membrane (Drosophila melanogaster)
MAP kinase activation (Drosophila melanogaster)
MAPK targets/ Nuclear events mediated by MAP kinases (Drosophila melanogaster)
CREB phosphorylation (Drosophila melanogaster)
RSK1/2/3 phosphorylates CREB at Serine 119 (Drosophila melanogaster)
Phospho-Ribosomal protein S6 kinase [nucleoplasm] (Drosophila melanogaster)
phospho-p-4S,T359,T573-RPS6KA1 [nucleoplasm] (Drosophila melanogaster)
ERK/MAPK targets (Drosophila melanogaster)
ERK1/2/5 activate RSK1/2/3 (Drosophila melanogaster)
Phospho-Ribosomal protein S6 kinase [nucleoplasm] (Drosophila melanogaster)
phospho-p-4S,T359,T573-RPS6KA1 [nucleoplasm] (Drosophila melanogaster)
Toll Like Receptor 2 (TLR2) Cascade (Drosophila melanogaster)
Toll Like Receptor TLR1:TLR2 Cascade (Drosophila melanogaster)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Drosophila melanogaster)
MAP kinase activation (Drosophila melanogaster)
MAPK targets/ Nuclear events mediated by MAP kinases (Drosophila melanogaster)
CREB phosphorylation (Drosophila melanogaster)
RSK1/2/3 phosphorylates CREB at Serine 119 (Drosophila melanogaster)
Phospho-Ribosomal protein S6 kinase [nucleoplasm] (Drosophila melanogaster)
phospho-p-4S,T359,T573-RPS6KA1 [nucleoplasm] (Drosophila melanogaster)
ERK/MAPK targets (Drosophila melanogaster)
ERK1/2/5 activate RSK1/2/3 (Drosophila melanogaster)
Phospho-Ribosomal protein S6 kinase [nucleoplasm] (Drosophila melanogaster)
phospho-p-4S,T359,T573-RPS6KA1 [nucleoplasm] (Drosophila melanogaster)
Toll Like Receptor TLR6:TLR2 Cascade (Drosophila melanogaster)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Drosophila melanogaster)
MAP kinase activation (Drosophila melanogaster)
MAPK targets/ Nuclear events mediated by MAP kinases (Drosophila melanogaster)
CREB phosphorylation (Drosophila melanogaster)
RSK1/2/3 phosphorylates CREB at Serine 119 (Drosophila melanogaster)
Phospho-Ribosomal protein S6 kinase [nucleoplasm] (Drosophila melanogaster)
phospho-p-4S,T359,T573-RPS6KA1 [nucleoplasm] (Drosophila melanogaster)
ERK/MAPK targets (Drosophila melanogaster)
ERK1/2/5 activate RSK1/2/3 (Drosophila melanogaster)
Phospho-Ribosomal protein S6 kinase [nucleoplasm] (Drosophila melanogaster)
phospho-p-4S,T359,T573-RPS6KA1 [nucleoplasm] (Drosophila melanogaster)
Toll Like Receptor 3 (TLR3) Cascade (Drosophila melanogaster)
MAP kinase activation (Drosophila melanogaster)
MAPK targets/ Nuclear events mediated by MAP kinases (Drosophila melanogaster)
CREB phosphorylation (Drosophila melanogaster)
RSK1/2/3 phosphorylates CREB at Serine 119 (Drosophila melanogaster)
Phospho-Ribosomal protein S6 kinase [nucleoplasm] (Drosophila melanogaster)
phospho-p-4S,T359,T573-RPS6KA1 [nucleoplasm] (Drosophila melanogaster)
ERK/MAPK targets (Drosophila melanogaster)
ERK1/2/5 activate RSK1/2/3 (Drosophila melanogaster)
Phospho-Ribosomal protein S6 kinase [nucleoplasm] (Drosophila melanogaster)
phospho-p-4S,T359,T573-RPS6KA1 [nucleoplasm] (Drosophila melanogaster)
Toll Like Receptor 4 (TLR4) Cascade (Drosophila melanogaster)
MyD88-independent TLR4 cascade (Drosophila melanogaster)
TRIF (TICAM1)-mediated TLR4 signaling (Drosophila melanogaster)
MAP kinase activation (Drosophila melanogaster)
MAPK targets/ Nuclear events mediated by MAP kinases (Drosophila melanogaster)
CREB phosphorylation (Drosophila melanogaster)
RSK1/2/3 phosphorylates CREB at Serine 119 (Drosophila melanogaster)
Phospho-Ribosomal protein S6 kinase [nucleoplasm] (Drosophila melanogaster)
phospho-p-4S,T359,T573-RPS6KA1 [nucleoplasm] (Drosophila melanogaster)
ERK/MAPK targets (Drosophila melanogaster)
ERK1/2/5 activate RSK1/2/3 (Drosophila melanogaster)
Phospho-Ribosomal protein S6 kinase [nucleoplasm] (Drosophila melanogaster)
phospho-p-4S,T359,T573-RPS6KA1 [nucleoplasm] (Drosophila melanogaster)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Drosophila melanogaster)
MAP kinase activation (Drosophila melanogaster)
MAPK targets/ Nuclear events mediated by MAP kinases (Drosophila melanogaster)
CREB phosphorylation (Drosophila melanogaster)
RSK1/2/3 phosphorylates CREB at Serine 119 (Drosophila melanogaster)
Phospho-Ribosomal protein S6 kinase [nucleoplasm] (Drosophila melanogaster)
phospho-p-4S,T359,T573-RPS6KA1 [nucleoplasm] (Drosophila melanogaster)
ERK/MAPK targets (Drosophila melanogaster)
ERK1/2/5 activate RSK1/2/3 (Drosophila melanogaster)
Phospho-Ribosomal protein S6 kinase [nucleoplasm] (Drosophila melanogaster)
phospho-p-4S,T359,T573-RPS6KA1 [nucleoplasm] (Drosophila melanogaster)
Toll Like Receptor 5 (TLR5) Cascade (Drosophila melanogaster)
MyD88 cascade initiated on plasma membrane (Drosophila melanogaster)
MAP kinase activation (Drosophila melanogaster)
MAPK targets/ Nuclear events mediated by MAP kinases (Drosophila melanogaster)
CREB phosphorylation (Drosophila melanogaster)
RSK1/2/3 phosphorylates CREB at Serine 119 (Drosophila melanogaster)
Phospho-Ribosomal protein S6 kinase [nucleoplasm] (Drosophila melanogaster)
phospho-p-4S,T359,T573-RPS6KA1 [nucleoplasm] (Drosophila melanogaster)
ERK/MAPK targets (Drosophila melanogaster)
ERK1/2/5 activate RSK1/2/3 (Drosophila melanogaster)
Phospho-Ribosomal protein S6 kinase [nucleoplasm] (Drosophila melanogaster)
phospho-p-4S,T359,T573-RPS6KA1 [nucleoplasm] (Drosophila melanogaster)
Toll Like Receptor 7/8 (TLR7/8) Cascade (Drosophila melanogaster)
MyD88 dependent cascade initiated on endosome (Drosophila melanogaster)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Drosophila melanogaster)
MAP kinase activation (Drosophila melanogaster)
MAPK targets/ Nuclear events mediated by MAP kinases (Drosophila melanogaster)
CREB phosphorylation (Drosophila melanogaster)
RSK1/2/3 phosphorylates CREB at Serine 119 (Drosophila melanogaster)
Phospho-Ribosomal protein S6 kinase [nucleoplasm] (Drosophila melanogaster)
phospho-p-4S,T359,T573-RPS6KA1 [nucleoplasm] (Drosophila melanogaster)
ERK/MAPK targets (Drosophila melanogaster)
ERK1/2/5 activate RSK1/2/3 (Drosophila melanogaster)
Phospho-Ribosomal protein S6 kinase [nucleoplasm] (Drosophila melanogaster)
phospho-p-4S,T359,T573-RPS6KA1 [nucleoplasm] (Drosophila melanogaster)
Toll Like Receptor 9 (TLR9) Cascade (Drosophila melanogaster)
MyD88 dependent cascade initiated on endosome (Drosophila melanogaster)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Drosophila melanogaster)
MAP kinase activation (Drosophila melanogaster)
MAPK targets/ Nuclear events mediated by MAP kinases (Drosophila melanogaster)
CREB phosphorylation (Drosophila melanogaster)
RSK1/2/3 phosphorylates CREB at Serine 119 (Drosophila melanogaster)
Phospho-Ribosomal protein S6 kinase [nucleoplasm] (Drosophila melanogaster)
phospho-p-4S,T359,T573-RPS6KA1 [nucleoplasm] (Drosophila melanogaster)
ERK/MAPK targets (Drosophila melanogaster)
ERK1/2/5 activate RSK1/2/3 (Drosophila melanogaster)
Phospho-Ribosomal protein S6 kinase [nucleoplasm] (Drosophila melanogaster)
phospho-p-4S,T359,T573-RPS6KA1 [nucleoplasm] (Drosophila melanogaster)
Neuronal System (Drosophila melanogaster)
Transmission across Chemical Synapses (Drosophila melanogaster)
Neurotransmitter receptors and postsynaptic signal transmission (Drosophila melanogaster)
Activation of NMDA receptors and postsynaptic events (Drosophila melanogaster)
Post NMDA receptor activation events (Drosophila melanogaster)
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling (Drosophila melanogaster)
Phosphorylation of CREB1 by ribosomal protein S6 kinases (RSKs) (Drosophila melanogaster)
p-S221,T359,S363,S380,T573,T732-RSK [nucleoplasm] (Drosophila melanogaster)
phospho-p-4S,T359,T573-RPS6KA1 [nucleoplasm] (Drosophila melanogaster)
RSK activation (Drosophila melanogaster)
p-S363,S380,T573 RS6K translocates to the nucleus (Drosophila melanogaster)
p-S221,T359,S363,S380,T573,T732-RSK [nucleoplasm] (Drosophila melanogaster)
phospho-p-4S,T359,T573-RPS6KA1 [nucleoplasm] (Drosophila melanogaster)
Signal Transduction (Drosophila melanogaster)
Signaling by GPCR (Drosophila melanogaster)
GPCR downstream signalling (Drosophila melanogaster)
G alpha (q) signalling events (Drosophila melanogaster)
Gastrin-CREB signalling pathway via PKC and MAPK (Drosophila melanogaster)
ERK1/2/5 activate RSK1/2/3 (Drosophila melanogaster)
Phospho-Ribosomal protein S6 kinase [nucleoplasm] (Drosophila melanogaster)
phospho-p-4S,T359,T573-RPS6KA1 [nucleoplasm] (Drosophila melanogaster)
RSK1/2/3 phosphorylates CREB at Serine 119 (Drosophila melanogaster)
Phospho-Ribosomal protein S6 kinase [nucleoplasm] (Drosophila melanogaster)
phospho-p-4S,T359,T573-RPS6KA1 [nucleoplasm] (Drosophila melanogaster)
Signaling by Receptor Tyrosine Kinases (Drosophila melanogaster)
Signaling by NTRKs (Drosophila melanogaster)
Signaling by NTRK1 (TRKA) (Drosophila melanogaster)
Nuclear Events (kinase and transcription factor activation) (Drosophila melanogaster)
CREB phosphorylation (Drosophila melanogaster)
RSK1/2/3 phosphorylates CREB at Serine 119 (Drosophila melanogaster)
Phospho-Ribosomal protein S6 kinase [nucleoplasm] (Drosophila melanogaster)
phospho-p-4S,T359,T573-RPS6KA1 [nucleoplasm] (Drosophila melanogaster)
ERK/MAPK targets (Drosophila melanogaster)
ERK1/2/5 activate RSK1/2/3 (Drosophila melanogaster)
Phospho-Ribosomal protein S6 kinase [nucleoplasm] (Drosophila melanogaster)
phospho-p-4S,T359,T573-RPS6KA1 [nucleoplasm] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:Q9VR61
Reference Genes
BioGPS Gene:33139
ENSEMBL:FBgn0262866
FlyBase:FBgn0262866
KEGG:dme:Dmel_CG17596
Monarch:33139
NCBI Gene:33139
UCSC:Q9VR61
Reference Transcript
RefSeq:NM_078713.3
RefSeq:NM_001272850.1
Other Identifiers
141623_at
1640019_at
33139
GO:0000166
GO:0000287
GO:0003824
GO:0004672
GO:0004674
GO:0004711
GO:0005515
GO:0005524
GO:0005654
GO:0005737
GO:0005829
GO:0006468
GO:0007474
GO:0007528
GO:0008306
GO:0008340
GO:0016301
GO:0016740
GO:0031594
GO:0034330
GO:0035106
GO:0035556
GO:0038202
GO:0042308
GO:0042683
GO:0043204
GO:0045475
GO:0046533
GO:0050877
GO:0050941
GO:0051019
GO:0070373
GO:0090101
GO:0098793
GO:0106310
GO:0140096
GO:1904396
Participates
as a member of
Phospho-Ribosomal protein S6 kinase [nucleoplasm] (Drosophila melanogaster)
p-S221,T359,S363,S380,T573,T732-RSK [nucleoplasm] (Drosophila melanogaster)
Other forms of this molecule
phospho-p-S232,T368,S372,S389,T581,S742-RPS6KA6 [nucleoplasm]
phospho-p-S218,T356,S360,S377,T570,T730-RPS6KA2 [nucleoplasm]
phospho-p-S227,T365,S369,S386,T577,T737-RPS6KA3 [nucleoplasm]
phospho-p-S232,T368,S372,S389,T581,S742-RPS6KA6 [cytosol]
phospho-p-S227,T365,S369,S386,T577,T737-RPS6KA3 [cytosol]
phospho-p-S221,T459,S363,S380,T573,S732-RPS6KA1 [cytosol]
phospho-p-S218,T356,S360,S377,T570,T730-RPS6KA2 [cytosol]
phospho-p-4S,T231,T365-RPS6KA3 [nucleoplasm]
phospho-p-4S,T356,T570-RPS6KA2 [nucleoplasm]
RPS6KA2 [nucleoplasm]
RPS6KA1 [nucleoplasm]
RPS6KA3 [nucleoplasm]
Inferred From
p-4S,T359,T573-RPS6KA1 [nucleoplasm]
(Homo sapiens)
p-S221,T359,S363,S380,T573,S732-RPS6KA1 [nucleoplasm]
(Homo sapiens)
Modified Residues
Name
O-phospho-L-serine at 221 (in Homo sapiens)
Coordinate
221
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 363 (in Homo sapiens)
Coordinate
363
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 380 (in Homo sapiens)
Coordinate
380
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 732 (in Homo sapiens)
Coordinate
732
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-threonine at 359 (in Homo sapiens)
Coordinate
359
PsiMod Name
O-phospho-L-threonine [MOD:00047]
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Name
O-phospho-L-threonine at 573 (in Homo sapiens)
Coordinate
573
PsiMod Name
O-phospho-L-threonine [MOD:00047]
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Cross References
RefSeq
NP_523437.2
,
NP_001259779.1
FlyBase
FBgn0262866
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