Reactome | Vha100-2 [endosome membrane]

Vha100-2 [endosome membrane]

Stable Identifier

R-DME-912595-2

Type

Protein [EntityWithAccessionedSequence]

Species

Drosophila melanogaster

Compartment

endosome membrane

Synonyms

ATP6V0A2, Q9VE75

Locations in the PathwayBrowser

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Signal Transduction (Drosophila melanogaster)

- Signaling by Receptor Tyrosine Kinases (Drosophila melanogaster)
  - Signaling by Insulin receptor (Drosophila melanogaster)
    - Insulin receptor recycling (Drosophila melanogaster)
      - ATP6AP1 binds V-ATPase (Drosophila melanogaster)
        
        V-ATPase [endosome membrane] (Drosophila melanogaster)
        
        ATP6V0 [endosome membrane] (Drosophila melanogaster)
        
        ATP6V0A [endosome membrane] (Drosophila melanogaster)
        
        Homologues of ATP6V0A2 [endosome membrane] (Drosophila melanogaster)
        
        Vha100-2 [endosome membrane] (Drosophila melanogaster)
        
        V-ATPase:ATP6AP1 [endosome membrane] (Drosophila melanogaster)
        
        V-ATPase [endosome membrane] (Drosophila melanogaster)
        
        ATP6V0 [endosome membrane] (Drosophila melanogaster)
        
        ATP6V0A [endosome membrane] (Drosophila melanogaster)
        
        Homologues of ATP6V0A2 [endosome membrane] (Drosophila melanogaster)
        
        Vha100-2 [endosome membrane] (Drosophila melanogaster)
      - Endosome acidification (Drosophila melanogaster)
        
        V-ATPase:ATP6AP1 [endosome membrane] (Drosophila melanogaster)
        
        V-ATPase [endosome membrane] (Drosophila melanogaster)
        
        ATP6V0 [endosome membrane] (Drosophila melanogaster)
        
        ATP6V0A [endosome membrane] (Drosophila melanogaster)
        
        Homologues of ATP6V0A2 [endosome membrane] (Drosophila melanogaster)
        
        Vha100-2 [endosome membrane] (Drosophila melanogaster)

Transport of small molecules (Drosophila melanogaster)

- Ion channel transport (Drosophila melanogaster)
  - ATP6AP1 binds V-ATPase (Drosophila melanogaster)
    - V-ATPase [endosome membrane] (Drosophila melanogaster)
      - ATP6V0 [endosome membrane] (Drosophila melanogaster)
        
        ATP6V0A [endosome membrane] (Drosophila melanogaster)
        
        Homologues of ATP6V0A2 [endosome membrane] (Drosophila melanogaster)
        
        Vha100-2 [endosome membrane] (Drosophila melanogaster)
    - V-ATPase:ATP6AP1 [endosome membrane] (Drosophila melanogaster)
      - V-ATPase [endosome membrane] (Drosophila melanogaster)
        
        ATP6V0 [endosome membrane] (Drosophila melanogaster)
        
        ATP6V0A [endosome membrane] (Drosophila melanogaster)
        
        Homologues of ATP6V0A2 [endosome membrane] (Drosophila melanogaster)
        
        Vha100-2 [endosome membrane] (Drosophila melanogaster)
- Iron uptake and transport (Drosophila melanogaster)
  - Transferrin endocytosis and recycling (Drosophila melanogaster)
    - ATP6AP1 binds V-ATPase (Drosophila melanogaster)
      - V-ATPase [endosome membrane] (Drosophila melanogaster)
        
        ATP6V0 [endosome membrane] (Drosophila melanogaster)
        
        ATP6V0A [endosome membrane] (Drosophila melanogaster)
        
        Homologues of ATP6V0A2 [endosome membrane] (Drosophila melanogaster)
        
        Vha100-2 [endosome membrane] (Drosophila melanogaster)
      - V-ATPase:ATP6AP1 [endosome membrane] (Drosophila melanogaster)
        
        V-ATPase [endosome membrane] (Drosophila melanogaster)
        
        ATP6V0 [endosome membrane] (Drosophila melanogaster)
        
        ATP6V0A [endosome membrane] (Drosophila melanogaster)
        
        Homologues of ATP6V0A2 [endosome membrane] (Drosophila melanogaster)
        
        Vha100-2 [endosome membrane] (Drosophila melanogaster)
    - Acidification of Tf:TfR1 containing endosome (Drosophila melanogaster)
      - V-ATPase:ATP6AP1 [endosome membrane] (Drosophila melanogaster)
        
        V-ATPase [endosome membrane] (Drosophila melanogaster)
        
        ATP6V0 [endosome membrane] (Drosophila melanogaster)
        
        ATP6V0A [endosome membrane] (Drosophila melanogaster)
        
        Homologues of ATP6V0A2 [endosome membrane] (Drosophila melanogaster)
        
        Vha100-2 [endosome membrane] (Drosophila melanogaster)

External Reference Information

External Reference

UniProt:Q9VE75

Gene Names

Vha100-2

Reference Genes

BioGPS Gene:42216 Vha100-2

CTD Gene:42216 Vha100-2

ENSEMBL:FBgn0028670

FlyBase:FBgn0028670

KEGG:dme:Dmel_CG18617 Vha100-2

Monarch:42216 Vha100-2

NCBI Gene:42216 Vha100-2

UCSC:Q9VE75 Vha100-2

Reference Transcript

Other Identifiers

142661_at

1631359_s_at

42216

GO:0000220

GO:0005886

GO:0006811

GO:0007035

GO:0016020

GO:0016471

GO:0033179

GO:0033181

GO:0046961

GO:0051117

GO:0055085

GO:1902600

Participates

as a member of

Homologues of ATP6V0A2 [endosome membrane] (Drosophila melanogaster)

Other forms of this molecule

Vha100-2 [lysosomal membrane]

Vha100-2 [phagocytic vesicle membrane]

Vha100-2 [plasma membrane]

Vha100-2 [ficolin-1-rich granule membrane]

Vha100-2 [endosome membrane]

Inferred From

ATP6V0A2 [endosome membrane] (Homo sapiens)

Cross References

RefSeq

NP_732337.1, NP_650722.1

FlyBase

FBgn0028670