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About
What is Reactome ?
News
Team
Scientific Advisory Board
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Editorial Calendar
Release Calendar
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Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
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Docs
Userguide
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How do I search ?
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CG10022 [cytosol]
Stable Identifier
R-DME-9016707
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
cytosol
Synonyms
CALM1, Q8IQ15
Locations in the PathwayBrowser
Expand all
Cellular responses to stimuli (Drosophila melanogaster)
Cellular responses to mechanical stimuli (Drosophila melanogaster)
Response of endothelial cells to shear stress (Drosophila melanogaster)
High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells (Drosophila melanogaster)
TRPV4 tetramer binds CALM1:Ca2+ (calmodulin:Ca2+) (Drosophila melanogaster)
CALM1:4xCa2+ [cytosol] (Drosophila melanogaster)
CG10022 [cytosol] (Drosophila melanogaster)
TRPV4 tetramer:CALM1:Ca2+ [plasma membrane] (Drosophila melanogaster)
CALM1:4xCa2+ [cytosol] (Drosophila melanogaster)
CG10022 [cytosol] (Drosophila melanogaster)
Hemostasis (Drosophila melanogaster)
Platelet activation, signaling and aggregation (Drosophila melanogaster)
Response to elevated platelet cytosolic Ca2+ (Drosophila melanogaster)
Platelet degranulation (Drosophila melanogaster)
Release of platelet cytosolic components (Drosophila melanogaster)
Platelet releasate cytosolic proteins [cytosol] (Drosophila melanogaster)
CG10022 [cytosol] (Drosophila melanogaster)
Platelet homeostasis (Drosophila melanogaster)
Platelet calcium homeostasis (Drosophila melanogaster)
Reduction of cytosolic Ca++ levels (Drosophila melanogaster)
SLC8A1,2,3 exchange 3Na+ for Ca2+ (Drosophila melanogaster)
CG10022 [cytosol] (Drosophila melanogaster)
Immune System (Drosophila melanogaster)
Adaptive Immune System (Drosophila melanogaster)
Signaling by the B Cell Receptor (BCR) (Drosophila melanogaster)
Downstream signaling events of B Cell Receptor (BCR) (Drosophila melanogaster)
Calcineurin activates NFAT (Drosophila melanogaster)
Calcineurin binds NFATC1,2,3 (Drosophila melanogaster)
CALM1:4xCa2+ [cytosol] (Drosophila melanogaster)
CG10022 [cytosol] (Drosophila melanogaster)
Calcineurin:p-NFATC1,2,3 [cytosol] (Drosophila melanogaster)
Calcineurin:Calmodulin (CaN:CaM) [cytosol] (Drosophila melanogaster)
PPP3CA,B:Calmodulin [cytosol] (Drosophila melanogaster)
CALM1:4xCa2+ [cytosol] (Drosophila melanogaster)
CG10022 [cytosol] (Drosophila melanogaster)
Innate Immune System (Drosophila melanogaster)
C-type lectin receptors (CLRs) (Drosophila melanogaster)
CLEC7A (Dectin-1) signaling (Drosophila melanogaster)
CLEC7A (Dectin-1) induces NFAT activation (Drosophila melanogaster)
Activation of Calcineurin (Drosophila melanogaster)
CALM1:4xCa2+ [cytosol] (Drosophila melanogaster)
CG10022 [cytosol] (Drosophila melanogaster)
Calcineurin:Calmodulin (CaN:CaM) [cytosol] (Drosophila melanogaster)
PPP3CA,B:Calmodulin [cytosol] (Drosophila melanogaster)
CALM1:4xCa2+ [cytosol] (Drosophila melanogaster)
CG10022 [cytosol] (Drosophila melanogaster)
Calcineurin binds and dephosphorylates NFAT (Drosophila melanogaster)
Calcineurin:Calmodulin (CaN:CaM) [cytosol] (Drosophila melanogaster)
PPP3CA,B:Calmodulin [cytosol] (Drosophila melanogaster)
CALM1:4xCa2+ [cytosol] (Drosophila melanogaster)
CG10022 [cytosol] (Drosophila melanogaster)
NFAT:CaN:CaM [cytosol] (Drosophila melanogaster)
Calcineurin:Calmodulin (CaN:CaM) [cytosol] (Drosophila melanogaster)
PPP3CA,B:Calmodulin [cytosol] (Drosophila melanogaster)
CALM1:4xCa2+ [cytosol] (Drosophila melanogaster)
CG10022 [cytosol] (Drosophila melanogaster)
Translocation of CaN:CaM:NFAT to nucleus (Drosophila melanogaster)
NFAT:CaN:CaM [cytosol] (Drosophila melanogaster)
Calcineurin:Calmodulin (CaN:CaM) [cytosol] (Drosophila melanogaster)
PPP3CA,B:Calmodulin [cytosol] (Drosophila melanogaster)
CALM1:4xCa2+ [cytosol] (Drosophila melanogaster)
CG10022 [cytosol] (Drosophila melanogaster)
Fc epsilon receptor (FCERI) signaling (Drosophila melanogaster)
FCERI mediated Ca+2 mobilization (Drosophila melanogaster)
Activation of Calcineurin (Drosophila melanogaster)
CALM1:4xCa2+ [cytosol] (Drosophila melanogaster)
CG10022 [cytosol] (Drosophila melanogaster)
Calcineurin:Calmodulin (CaN:CaM) [cytosol] (Drosophila melanogaster)
PPP3CA,B:Calmodulin [cytosol] (Drosophila melanogaster)
CALM1:4xCa2+ [cytosol] (Drosophila melanogaster)
CG10022 [cytosol] (Drosophila melanogaster)
Calcineurin binds and dephosphorylates NFAT (Drosophila melanogaster)
Calcineurin:Calmodulin (CaN:CaM) [cytosol] (Drosophila melanogaster)
PPP3CA,B:Calmodulin [cytosol] (Drosophila melanogaster)
CALM1:4xCa2+ [cytosol] (Drosophila melanogaster)
CG10022 [cytosol] (Drosophila melanogaster)
NFAT:CaN:CaM [cytosol] (Drosophila melanogaster)
Calcineurin:Calmodulin (CaN:CaM) [cytosol] (Drosophila melanogaster)
PPP3CA,B:Calmodulin [cytosol] (Drosophila melanogaster)
CALM1:4xCa2+ [cytosol] (Drosophila melanogaster)
CG10022 [cytosol] (Drosophila melanogaster)
Translocation of CaN:CaM:NFAT to nucleus (Drosophila melanogaster)
NFAT:CaN:CaM [cytosol] (Drosophila melanogaster)
Calcineurin:Calmodulin (CaN:CaM) [cytosol] (Drosophila melanogaster)
PPP3CA,B:Calmodulin [cytosol] (Drosophila melanogaster)
CALM1:4xCa2+ [cytosol] (Drosophila melanogaster)
CG10022 [cytosol] (Drosophila melanogaster)
Metabolism (Drosophila melanogaster)
Inositol phosphate metabolism (Drosophila melanogaster)
Synthesis of IP3 and IP4 in the cytosol (Drosophila melanogaster)
I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by ITPKA/B/C in the cytosol (Drosophila melanogaster)
ITPKA/B/C [cytosol] (Drosophila melanogaster)
ITPKA:Ca2+:CALM1 [cytosol] (Drosophila melanogaster)
CG10022 [cytosol] (Drosophila melanogaster)
ITPKB:Ca2+:CALM1 [cytosol] (Drosophila melanogaster)
CG10022 [cytosol] (Drosophila melanogaster)
Metabolism of carbohydrates (Drosophila melanogaster)
Glycogen metabolism (Drosophila melanogaster)
Glycogen breakdown (glycogenolysis) (Drosophila melanogaster)
glycogen phosphorylase (PYGM) dimer b + 2 ATP => glycogen phosphorylase (PYGM) dimer a + 2 ADP (Drosophila melanogaster)
phosphorylase kinase complex (PHKM) [cytosol] (Drosophila melanogaster)
CG10022 [cytosol] (Drosophila melanogaster)
Metabolism of nitric oxide: NOS3 activation and regulation (Drosophila melanogaster)
eNOS activation (Drosophila melanogaster)
AKT1 phosphorylates eNOS (Drosophila melanogaster)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Drosophila melanogaster)
CALM1:4xCa2+ [cytosol] (Drosophila melanogaster)
CG10022 [cytosol] (Drosophila melanogaster)
BH2 binding can lead to eNOS uncoupling (Drosophila melanogaster)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH2 [plasma membrane] (Drosophila melanogaster)
CALM1:4xCa2+ [cytosol] (Drosophila melanogaster)
CG10022 [cytosol] (Drosophila melanogaster)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Drosophila melanogaster)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Drosophila melanogaster)
CALM1:4xCa2+ [cytosol] (Drosophila melanogaster)
CG10022 [cytosol] (Drosophila melanogaster)
The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle (Drosophila melanogaster)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Drosophila melanogaster)
CALM1:4xCa2+ [cytosol] (Drosophila melanogaster)
CG10022 [cytosol] (Drosophila melanogaster)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Drosophila melanogaster)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Drosophila melanogaster)
CALM1:4xCa2+ [cytosol] (Drosophila melanogaster)
CG10022 [cytosol] (Drosophila melanogaster)
Uncoupled eNOS favours the formation of superoxide (Drosophila melanogaster)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH2 [plasma membrane] (Drosophila melanogaster)
CALM1:4xCa2+ [cytosol] (Drosophila melanogaster)
CG10022 [cytosol] (Drosophila melanogaster)
eNOS synthesizes NO (Drosophila melanogaster)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Drosophila melanogaster)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Drosophila melanogaster)
CALM1:4xCa2+ [cytosol] (Drosophila melanogaster)
CG10022 [cytosol] (Drosophila melanogaster)
Metabolism of vitamins and cofactors (Drosophila melanogaster)
Metabolism of cofactors (Drosophila melanogaster)
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation (Drosophila melanogaster)
BH2 binding can lead to eNOS uncoupling (Drosophila melanogaster)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH2 [plasma membrane] (Drosophila melanogaster)
CALM1:4xCa2+ [cytosol] (Drosophila melanogaster)
CG10022 [cytosol] (Drosophila melanogaster)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Drosophila melanogaster)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Drosophila melanogaster)
CALM1:4xCa2+ [cytosol] (Drosophila melanogaster)
CG10022 [cytosol] (Drosophila melanogaster)
The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle (Drosophila melanogaster)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Drosophila melanogaster)
CALM1:4xCa2+ [cytosol] (Drosophila melanogaster)
CG10022 [cytosol] (Drosophila melanogaster)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Drosophila melanogaster)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Drosophila melanogaster)
CALM1:4xCa2+ [cytosol] (Drosophila melanogaster)
CG10022 [cytosol] (Drosophila melanogaster)
Metabolism of proteins (Drosophila melanogaster)
Post-translational protein modification (Drosophila melanogaster)
Protein methylation (Drosophila melanogaster)
KAMKMT transfers 3xCH3 groups from 3xAdoMet to CALM1 (Drosophila melanogaster)
CG10022 [cytosol] (Drosophila melanogaster)
Muscle contraction (Drosophila melanogaster)
Cardiac conduction (Drosophila melanogaster)
Ion homeostasis (Drosophila melanogaster)
ATP2A1-3 transport Ca2+ from cytosol to ER lumen (Drosophila melanogaster)
CAMK2 heteromer:CALM:4xCa2+ [plasma membrane] (Drosophila melanogaster)
CALM1:4xCa2+ [cytosol] (Drosophila melanogaster)
CG10022 [cytosol] (Drosophila melanogaster)
SLC8A1,2,3 exchange 3Na+ for Ca2+ (Drosophila melanogaster)
CG10022 [cytosol] (Drosophila melanogaster)
Neuronal System (Drosophila melanogaster)
Transmission across Chemical Synapses (Drosophila melanogaster)
Neurotransmitter receptors and postsynaptic signal transmission (Drosophila melanogaster)
Activation of NMDA receptors and postsynaptic events (Drosophila melanogaster)
Post NMDA receptor activation events (Drosophila melanogaster)
Activation of RAC1 downstream of NMDARs (Drosophila melanogaster)
CAMK1 binds calmodulin (Drosophila melanogaster)
CALM1:4xCa2+ [cytosol] (Drosophila melanogaster)
CG10022 [cytosol] (Drosophila melanogaster)
CAMK1:CALM1:4xCa2+ [cytosol] (Drosophila melanogaster)
CALM1:4xCa2+ [cytosol] (Drosophila melanogaster)
CG10022 [cytosol] (Drosophila melanogaster)
Unblocking of NMDA receptors, glutamate binding and activation (Drosophila melanogaster)
Membrane depolarization upon activation of Ca impermeable AMPA receptors (Drosophila melanogaster)
Gly,D-Ser:L-Glu:GRIN1:GRIN2B NMDA receptors:p-T286-CaMKII dodecamer:CALM1:4xCa2+ [plasma membrane] (Drosophila melanogaster)
p-T286-CaMKII dodecamer:CALM1:4xCa2+ [cytosol] (Drosophila melanogaster)
CALM1:4xCa2+ [cytosol] (Drosophila melanogaster)
CG10022 [cytosol] (Drosophila melanogaster)
Activation of kainate receptors upon glutamate binding (Drosophila melanogaster)
Ionotropic activity of kainate receptors (Drosophila melanogaster)
Activation of Ca-permeable Kainate Receptor (Drosophila melanogaster)
Activation of Ca-permeable Kainate receptors (Drosophila melanogaster)
Kainate receptor-glutamate complex [plasma membrane] (Drosophila melanogaster)
Kainate Receptors [plasma membrane] (Drosophila melanogaster)
GRIK 2 homomer [plasma membrane] (Drosophila melanogaster)
GRIK2 interacting proteins [plasma membrane] (Drosophila melanogaster)
CG10022 [cytosol] (Drosophila melanogaster)
kainate receptor binds glutamate (Drosophila melanogaster)
Kainate Receptors [plasma membrane] (Drosophila melanogaster)
GRIK 2 homomer [plasma membrane] (Drosophila melanogaster)
GRIK2 interacting proteins [plasma membrane] (Drosophila melanogaster)
CG10022 [cytosol] (Drosophila melanogaster)
Kainate receptor-glutamate complex [plasma membrane] (Drosophila melanogaster)
Kainate Receptors [plasma membrane] (Drosophila melanogaster)
GRIK 2 homomer [plasma membrane] (Drosophila melanogaster)
GRIK2 interacting proteins [plasma membrane] (Drosophila melanogaster)
CG10022 [cytosol] (Drosophila melanogaster)
Sensory Perception (Drosophila melanogaster)
Visual phototransduction (Drosophila melanogaster)
The phototransduction cascade (Drosophila melanogaster)
Inactivation, recovery and regulation of the phototransduction cascade (Drosophila melanogaster)
CALM1:Ca2+ binds CNG channel (Drosophila melanogaster)
CALM1:4xCa2+ [cytosol] (Drosophila melanogaster)
CG10022 [cytosol] (Drosophila melanogaster)
CALM1:Ca2+:CNG channel [plasma membrane] (Drosophila melanogaster)
CALM1:4xCa2+ [cytosol] (Drosophila melanogaster)
CG10022 [cytosol] (Drosophila melanogaster)
KAMKMT transfers 3xCH3 groups from 3xAdoMet to CALM1 (Drosophila melanogaster)
CG10022 [cytosol] (Drosophila melanogaster)
Signal Transduction (Drosophila melanogaster)
Intracellular signaling by second messengers (Drosophila melanogaster)
DAG and IP3 signaling (Drosophila melanogaster)
CaM pathway (Drosophila melanogaster)
Calmodulin induced events (Drosophila melanogaster)
Cam-PDE 1 activation (Drosophila melanogaster)
Calmodulin activates Cam-PDE 1 (Drosophila melanogaster)
CALM1:4xCa2+ [cytosol] (Drosophila melanogaster)
CG10022 [cytosol] (Drosophila melanogaster)
GRK2 binds CALM1:4Ca2+ (Drosophila melanogaster)
CALM1:4xCa2+ [cytosol] (Drosophila melanogaster)
CG10022 [cytosol] (Drosophila melanogaster)
GRK2:CALM1:4xCa2+ [plasma membrane] (Drosophila melanogaster)
CALM1:4xCa2+ [cytosol] (Drosophila melanogaster)
CG10022 [cytosol] (Drosophila melanogaster)
PKA-mediated phosphorylation of CREB (Drosophila melanogaster)
PKA activation (Drosophila melanogaster)
Adenylate cyclase produces cAMP (Drosophila melanogaster)
CALM1:4xCa2+ [cytosol] (Drosophila melanogaster)
CG10022 [cytosol] (Drosophila melanogaster)
MAPK family signaling cascades (Drosophila melanogaster)
MAPK1/MAPK3 signaling (Drosophila melanogaster)
RAF/MAP kinase cascade (Drosophila melanogaster)
RAF activation (Drosophila melanogaster)
Phosphorylation of RAF (Drosophila melanogaster)
RAF activating kinases [plasma membrane] (Drosophila melanogaster)
p-T286-CaMKII dodecamer:CALM1:4xCa2+ [cytosol] (Drosophila melanogaster)
CALM1:4xCa2+ [cytosol] (Drosophila melanogaster)
CG10022 [cytosol] (Drosophila melanogaster)
RAS processing (Drosophila melanogaster)
ARL2:GTP bind PDE6D on KRAS4B (Drosophila melanogaster)
S-Farn-Me KRAS4B:CALM1:4xCa2+:PDE6D [cytosol] (Drosophila melanogaster)
S-Farn-Me KRAS4B:CALM1:4xCa2+ [cytosol] (Drosophila melanogaster)
CALM1:4xCa2+ [cytosol] (Drosophila melanogaster)
CG10022 [cytosol] (Drosophila melanogaster)
S-Farn-Me KRAS4B:CALM1:4xCa2+:PDE6D:ARL2:GTP [cytosol] (Drosophila melanogaster)
S-Farn-Me KRAS4B:CALM1:4xCa2+:PDE6D [cytosol] (Drosophila melanogaster)
S-Farn-Me KRAS4B:CALM1:4xCa2+ [cytosol] (Drosophila melanogaster)
CALM1:4xCa2+ [cytosol] (Drosophila melanogaster)
CG10022 [cytosol] (Drosophila melanogaster)
Calmodulin dissociates KRAS4B from the plasma membrane (Drosophila melanogaster)
S-Farn-Me KRAS4B:CALM1:4xCa2+ [cytosol] (Drosophila melanogaster)
CALM1:4xCa2+ [cytosol] (Drosophila melanogaster)
CG10022 [cytosol] (Drosophila melanogaster)
S-Farn-Me KRAS4B:CALM1:4xCa2+ [plasma membrane] (Drosophila melanogaster)
CALM1:4xCa2+ [cytosol] (Drosophila melanogaster)
CG10022 [cytosol] (Drosophila melanogaster)
KRAS4B recycles to the plasma membrane (Drosophila melanogaster)
CALM1:4xCa2+ [cytosol] (Drosophila melanogaster)
CG10022 [cytosol] (Drosophila melanogaster)
S-Farn-Me KRAS4B:CALM1:4xCa2+:PDE6D:ARL2:GTP [cytosol] (Drosophila melanogaster)
S-Farn-Me KRAS4B:CALM1:4xCa2+:PDE6D [cytosol] (Drosophila melanogaster)
S-Farn-Me KRAS4B:CALM1:4xCa2+ [cytosol] (Drosophila melanogaster)
CALM1:4xCa2+ [cytosol] (Drosophila melanogaster)
CG10022 [cytosol] (Drosophila melanogaster)
PDE6D binds S-Farn-Me KRAS4B:CALM:4 Ca2+ (Drosophila melanogaster)
S-Farn-Me KRAS4B:CALM1:4xCa2+ [cytosol] (Drosophila melanogaster)
CALM1:4xCa2+ [cytosol] (Drosophila melanogaster)
CG10022 [cytosol] (Drosophila melanogaster)
S-Farn-Me KRAS4B:CALM1:4xCa2+:PDE6D [cytosol] (Drosophila melanogaster)
S-Farn-Me KRAS4B:CALM1:4xCa2+ [cytosol] (Drosophila melanogaster)
CALM1:4xCa2+ [cytosol] (Drosophila melanogaster)
CG10022 [cytosol] (Drosophila melanogaster)
S-Farn-Me KRAS4B binds calmodulin (Drosophila melanogaster)
CALM1:4xCa2+ [cytosol] (Drosophila melanogaster)
CG10022 [cytosol] (Drosophila melanogaster)
S-Farn-Me KRAS4B:CALM1:4xCa2+ [plasma membrane] (Drosophila melanogaster)
CALM1:4xCa2+ [cytosol] (Drosophila melanogaster)
CG10022 [cytosol] (Drosophila melanogaster)
Signaling by GPCR (Drosophila melanogaster)
GPCR downstream signalling (Drosophila melanogaster)
G alpha (i) signalling events (Drosophila melanogaster)
Opioid Signalling (Drosophila melanogaster)
G-protein mediated events (Drosophila melanogaster)
PLC beta mediated events (Drosophila melanogaster)
Ca-dependent events (Drosophila melanogaster)
CaM pathway (Drosophila melanogaster)
Calmodulin induced events (Drosophila melanogaster)
Cam-PDE 1 activation (Drosophila melanogaster)
Calmodulin activates Cam-PDE 1 (Drosophila melanogaster)
CALM1:4xCa2+ [cytosol] (Drosophila melanogaster)
CG10022 [cytosol] (Drosophila melanogaster)
GRK2 binds CALM1:4Ca2+ (Drosophila melanogaster)
CALM1:4xCa2+ [cytosol] (Drosophila melanogaster)
CG10022 [cytosol] (Drosophila melanogaster)
GRK2:CALM1:4xCa2+ [plasma membrane] (Drosophila melanogaster)
CALM1:4xCa2+ [cytosol] (Drosophila melanogaster)
CG10022 [cytosol] (Drosophila melanogaster)
PKA-mediated phosphorylation of CREB (Drosophila melanogaster)
PKA activation (Drosophila melanogaster)
Adenylate cyclase produces cAMP (Drosophila melanogaster)
CALM1:4xCa2+ [cytosol] (Drosophila melanogaster)
CG10022 [cytosol] (Drosophila melanogaster)
Signaling by Nuclear Receptors (Drosophila melanogaster)
ESR-mediated signaling (Drosophila melanogaster)
Extra-nuclear estrogen signaling (Drosophila melanogaster)
eNOS synthesizes NO (Drosophila melanogaster)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Drosophila melanogaster)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Drosophila melanogaster)
CALM1:4xCa2+ [cytosol] (Drosophila melanogaster)
CG10022 [cytosol] (Drosophila melanogaster)
Signaling by Receptor Tyrosine Kinases (Drosophila melanogaster)
Signaling by VEGF (Drosophila melanogaster)
VEGFA-VEGFR2 Pathway (Drosophila melanogaster)
VEGFR2 mediated vascular permeability (Drosophila melanogaster)
AKT1 phosphorylates eNOS (Drosophila melanogaster)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Drosophila melanogaster)
CALM1:4xCa2+ [cytosol] (Drosophila melanogaster)
CG10022 [cytosol] (Drosophila melanogaster)
The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle (Drosophila melanogaster)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Drosophila melanogaster)
CALM1:4xCa2+ [cytosol] (Drosophila melanogaster)
CG10022 [cytosol] (Drosophila melanogaster)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Drosophila melanogaster)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Drosophila melanogaster)
CALM1:4xCa2+ [cytosol] (Drosophila melanogaster)
CG10022 [cytosol] (Drosophila melanogaster)
eNOS synthesizes NO (Drosophila melanogaster)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Drosophila melanogaster)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Drosophila melanogaster)
CALM1:4xCa2+ [cytosol] (Drosophila melanogaster)
CG10022 [cytosol] (Drosophila melanogaster)
Signaling by WNT (Drosophila melanogaster)
Beta-catenin independent WNT signaling (Drosophila melanogaster)
Ca2+ pathway (Drosophila melanogaster)
Activation of Calcineurin (Drosophila melanogaster)
CALM1:4xCa2+ [cytosol] (Drosophila melanogaster)
CG10022 [cytosol] (Drosophila melanogaster)
Calcineurin:Calmodulin (CaN:CaM) [cytosol] (Drosophila melanogaster)
PPP3CA,B:Calmodulin [cytosol] (Drosophila melanogaster)
CALM1:4xCa2+ [cytosol] (Drosophila melanogaster)
CG10022 [cytosol] (Drosophila melanogaster)
Active calmodulin binds CAMK2 (Drosophila melanogaster)
CALM1:4xCa2+ [cytosol] (Drosophila melanogaster)
CG10022 [cytosol] (Drosophila melanogaster)
CAMK2:CaM [cytosol] (Drosophila melanogaster)
CALM1:4xCa2+ [cytosol] (Drosophila melanogaster)
CG10022 [cytosol] (Drosophila melanogaster)
S-Farn-Me KRAS4B:CALM1:4xCa2+ [plasma membrane] (Drosophila melanogaster)
CALM1:4xCa2+ [cytosol] (Drosophila melanogaster)
CG10022 [cytosol] (Drosophila melanogaster)
Autophosphorylation and activation of CAMK2 (Drosophila melanogaster)
CAMK2:CaM [cytosol] (Drosophila melanogaster)
CALM1:4xCa2+ [cytosol] (Drosophila melanogaster)
CG10022 [cytosol] (Drosophila melanogaster)
p-T286 CAMK2:CaM [cytosol] (Drosophila melanogaster)
CALM1:4xCa2+ [cytosol] (Drosophila melanogaster)
CG10022 [cytosol] (Drosophila melanogaster)
Calcineurin binds and dephosphorylates NFAT1 in response to WNT/Ca2+ signaling (Drosophila melanogaster)
Calcineurin:Calmodulin (CaN:CaM) [cytosol] (Drosophila melanogaster)
PPP3CA,B:Calmodulin [cytosol] (Drosophila melanogaster)
CALM1:4xCa2+ [cytosol] (Drosophila melanogaster)
CG10022 [cytosol] (Drosophila melanogaster)
NFATC1:CaN:CaM [cytosol] (Drosophila melanogaster)
Calcineurin:Calmodulin (CaN:CaM) [cytosol] (Drosophila melanogaster)
PPP3CA,B:Calmodulin [cytosol] (Drosophila melanogaster)
CALM1:4xCa2+ [cytosol] (Drosophila melanogaster)
CG10022 [cytosol] (Drosophila melanogaster)
Dissociation of CaM and CAMK2 autophosphorylation (Drosophila melanogaster)
CALM1:4xCa2+ [cytosol] (Drosophila melanogaster)
CG10022 [cytosol] (Drosophila melanogaster)
p-T286 CAMK2:CaM [cytosol] (Drosophila melanogaster)
CALM1:4xCa2+ [cytosol] (Drosophila melanogaster)
CG10022 [cytosol] (Drosophila melanogaster)
Translocation of NFATC1:CaN:CaM to nucleus (Drosophila melanogaster)
NFATC1:CaN:CaM [cytosol] (Drosophila melanogaster)
Calcineurin:Calmodulin (CaN:CaM) [cytosol] (Drosophila melanogaster)
PPP3CA,B:Calmodulin [cytosol] (Drosophila melanogaster)
CALM1:4xCa2+ [cytosol] (Drosophila melanogaster)
CG10022 [cytosol] (Drosophila melanogaster)
Transport of small molecules (Drosophila melanogaster)
Ion channel transport (Drosophila melanogaster)
Ion transport by P-type ATPases (Drosophila melanogaster)
ATP2A1-3 transport Ca2+ from cytosol to ER lumen (Drosophila melanogaster)
CAMK2 heteromer:CALM:4xCa2+ [plasma membrane] (Drosophila melanogaster)
CALM1:4xCa2+ [cytosol] (Drosophila melanogaster)
CG10022 [cytosol] (Drosophila melanogaster)
SLC-mediated transmembrane transport (Drosophila melanogaster)
Transport of inorganic cations/anions and amino acids/oligopeptides (Drosophila melanogaster)
Sodium/Calcium exchangers (Drosophila melanogaster)
SLC8A1,2,3 exchange 3Na+ for Ca2+ (Drosophila melanogaster)
CG10022 [cytosol] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:Q8IQ15
Gene Names
CG10022
Reference Genes
BioGPS Gene:319047 CG10022
ENSEMBL:FBgn0051960
FlyBase:FBgn0051960
KEGG:dme:Dmel_CG31960 CG10022
Monarch:319047 CG10022
NCBI Gene:319047 CG10022
UCSC:Q8IQ15 CG10022
Reference Transcript
RefSeq:NM_164559.2 CG10022
Other Identifiers
145738_at
1636589_s_at
1640076_at
319047
GO:0005509
GO:0005737
GO:0019722
GO:0030234
GO:0098772
Participates
as a member of
Platelet releasate cytosolic proteins [cytosol] (Drosophila melanogaster)
as an input of
KAMKMT transfers 3xCH3 groups from 3xAdoMet to CALM1 (Drosophila melanogaster)
as a component of
phosphorylase kinase complex (PHKM) [cytosol] (Drosophila melanogaster)
GRIK2 interacting proteins [plasma membrane] (Drosophila melanogaster)
ITPKB:Ca2+:CALM1 [cytosol] (Drosophila melanogaster)
ITPKA:Ca2+:CALM1 [cytosol] (Drosophila melanogaster)
CALM1:4xCa2+ [cytosol] (Drosophila melanogaster)
This entity regulates
Negatively
SLC8A1,2,3 exchange 3Na+ for Ca2+
(Drosophila melanogaster)
Other forms of this molecule
CG10022 [extracellular region]
CG10022 [cytosol]
CG10022 [extracellular region]
CG10022 [ficolin-1-rich granule lumen]
CG10022 [plasma membrane]
CG10022 [nucleoplasm]
Inferred From
CALM1 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_722942.1
ENSEMBL
FBpp0077183
,
FBtr0077494
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