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eIF4G1 [cytosol]
Stable Identifier
R-DME-72584
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
cytosol
Synonyms
EIF4G1, A8DZ29
Locations in the PathwayBrowser
Expand all
Metabolism of RNA (Drosophila melanogaster)
Deadenylation-dependent mRNA decay (Drosophila melanogaster)
Deadenylation of mRNA (Drosophila melanogaster)
PAN2-PAN3 complex partially deadenylates mRNA (Drosophila melanogaster)
Partially Deadenylated mRNA Complex [cytosol] (Drosophila melanogaster)
eIF4G1 [cytosol] (Drosophila melanogaster)
Translatable mRNA Complex [cytosol] (Drosophila melanogaster)
eIF4G1 [cytosol] (Drosophila melanogaster)
Nonsense-Mediated Decay (NMD) (Drosophila melanogaster)
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) (Drosophila melanogaster)
SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Drosophila melanogaster)
SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Drosophila melanogaster)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Drosophila melanogaster)
mRNA Complex with a Premature Termination Codon Preceding an Exon Junction [cytosol] (Drosophila melanogaster)
eIF4G1 [cytosol] (Drosophila melanogaster)
SMG1:UPF1:EJC:Translated mRNP [cytosol] (Drosophila melanogaster)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Drosophila melanogaster)
mRNA Complex with a Premature Termination Codon Preceding an Exon Junction [cytosol] (Drosophila melanogaster)
eIF4G1 [cytosol] (Drosophila melanogaster)
SMG6 hydrolyzes mRNA with premature termination codon (Drosophila melanogaster)
Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (Drosophila melanogaster)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Drosophila melanogaster)
mRNA Complex with a Premature Termination Codon Preceding an Exon Junction [cytosol] (Drosophila melanogaster)
eIF4G1 [cytosol] (Drosophila melanogaster)
mRNA Cleaved by SMG6 [cytosol] (Drosophila melanogaster)
eIF4G1 [cytosol] (Drosophila melanogaster)
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) (Drosophila melanogaster)
Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex (Drosophila melanogaster)
Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Drosophila melanogaster)
mRNA Complex with a Premature Termination Codon Not Preceding an Exon Junction [cytosol] (Drosophila melanogaster)
eIF4G1 [cytosol] (Drosophila melanogaster)
UPF1:eRF3 Complex on Translated mRNA [cytosol] (Drosophila melanogaster)
Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Drosophila melanogaster)
mRNA Complex with a Premature Termination Codon Not Preceding an Exon Junction [cytosol] (Drosophila melanogaster)
eIF4G1 [cytosol] (Drosophila melanogaster)
Regulation of mRNA stability by proteins that bind AU-rich elements (Drosophila melanogaster)
AUF1 (hnRNP D0) binds and destabilizes mRNA (Drosophila melanogaster)
AUF1 (hnRNP D0) is ubiquitinylated (Drosophila melanogaster)
AUF1 Complexed with Translation and Heat Shock Proteins [cytosol] (Drosophila melanogaster)
eIF4G1 [cytosol] (Drosophila melanogaster)
Metabolism of proteins (Drosophila melanogaster)
Translation (Drosophila melanogaster)
Eukaryotic Translation Initiation (Drosophila melanogaster)
Cap-dependent Translation Initiation (Drosophila melanogaster)
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S (Drosophila melanogaster)
Formation of the cap-binding eIF4F complex (Drosophila melanogaster)
eIF4F [cytosol] (Drosophila melanogaster)
eIF4G1 [cytosol] (Drosophila melanogaster)
eIF4G1 [cytosol] (Drosophila melanogaster)
Translation initiation complex formation (Drosophila melanogaster)
Formation of translation initiation complexes containing mRNA that does not circularize (Drosophila melanogaster)
48S complex [cytosol] (Drosophila melanogaster)
eIF4F [cytosol] (Drosophila melanogaster)
eIF4G1 [cytosol] (Drosophila melanogaster)
mRNA:eIF4F:eIF4B:eIF4H [cytosol] (Drosophila melanogaster)
eIF4F [cytosol] (Drosophila melanogaster)
eIF4G1 [cytosol] (Drosophila melanogaster)
Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation (Drosophila melanogaster)
43S: Ceruloplasmin mRNA:eIF4F:eIF4B:eIF4H:PABP [cytosol] (Drosophila melanogaster)
eIF4F [cytosol] (Drosophila melanogaster)
eIF4G1 [cytosol] (Drosophila melanogaster)
Ceruloplasmin mRNA:eIF4F:eIF4B:eIF4H [cytosol] (Drosophila melanogaster)
eIF4F [cytosol] (Drosophila melanogaster)
eIF4G1 [cytosol] (Drosophila melanogaster)
Ribosomal scanning and start codon recognition (Drosophila melanogaster)
Ribosomal scanning (Drosophila melanogaster)
48S complex [cytosol] (Drosophila melanogaster)
eIF4F [cytosol] (Drosophila melanogaster)
eIF4G1 [cytosol] (Drosophila melanogaster)
Start codon recognition (Drosophila melanogaster)
48S complex [cytosol] (Drosophila melanogaster)
eIF4F [cytosol] (Drosophila melanogaster)
eIF4G1 [cytosol] (Drosophila melanogaster)
L13a-mediated translational silencing of Ceruloplasmin expression (Drosophila melanogaster)
Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA (Drosophila melanogaster)
43S: Ceruloplasmin mRNA:eIF4F:eIF4B:eIF4H:PABP [cytosol] (Drosophila melanogaster)
eIF4F [cytosol] (Drosophila melanogaster)
eIF4G1 [cytosol] (Drosophila melanogaster)
phospho-L13a associated wth the 3' UTR GAIT element of ceruloplasmin mRNA within the translation initiation complex [cytosol] (Drosophila melanogaster)
43S: Ceruloplasmin mRNA:eIF4F:eIF4B:eIF4H:PABP [cytosol] (Drosophila melanogaster)
eIF4F [cytosol] (Drosophila melanogaster)
eIF4G1 [cytosol] (Drosophila melanogaster)
Signal Transduction (Drosophila melanogaster)
MTOR signalling (Drosophila melanogaster)
mTORC1-mediated signalling (Drosophila melanogaster)
Phosphorylation and activation of eIF4G by activated S6K1 (Drosophila melanogaster)
eIF4G1 [cytosol] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:A8DZ29
Gene Names
eIF4G1
Reference Genes
BioGPS Gene:43839 eIF4G1
ENSEMBL:FBgn0023213
FlyBase:FBgn0023213
KEGG:dme:Dmel_CG10811 eIF4G1
Monarch:43839 eIF4G1
NCBI Gene:43839 eIF4G1
UCSC:A8DZ29 eIF4G1
Reference Transcript
RefSeq:NM_001103382.2 eIF4G1
Other Identifiers
153267_at
1637560_at
43839
GO:0000278
GO:0000340
GO:0003723
GO:0003729
GO:0003743
GO:0005515
GO:0005829
GO:0006412
GO:0006413
GO:0006417
GO:0008190
GO:0016281
Participates
as a component of
AUF1 Complexed with Translation and Heat Shock Proteins [cytosol] (Drosophila melanogaster)
mRNA Cleaved by SMG6 [cytosol] (Drosophila melanogaster)
mRNA Complex with a Premature Termination Codon Preceding an Exon Junction [cytosol] (Drosophila melanogaster)
mRNA Complex with a Premature Termination Codon Not Preceding an Exon Junction [cytosol] (Drosophila melanogaster)
Translatable mRNA Complex [cytosol] (Drosophila melanogaster)
Partially Deadenylated mRNA Complex [cytosol] (Drosophila melanogaster)
eIF4F [cytosol] (Drosophila melanogaster)
as an input of
Phosphorylation and activation of eIF4G by activated S6K1 (Drosophila melanogaster)
Formation of the cap-binding eIF4F complex (Drosophila melanogaster)
Other forms of this molecule
phospho-eIF4G1 [cytosol]
Inferred From
EIF4G1 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_001096852.1
FlyBase
FBgn0023213
GlyGen
A8DZ29
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