Reactome | Ogdh2 [mitochondrial matrix]

Ogdh2 [mitochondrial matrix]

Stable Identifier

R-DME-69981-2

Type

Protein [EntityWithAccessionedSequence]

Species

Drosophila melanogaster

Compartment

mitochondrial matrix

Synonyms

OGDH, Q95T35

Locations in the PathwayBrowser

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Metabolism (Drosophila melanogaster)

- Aerobic respiration and respiratory electron transport (Drosophila melanogaster)
  - Citric acid cycle (TCA cycle) (Drosophila melanogaster)
    - OGDH complex synthesizes succinyl-CoA from 2-OG (Drosophila melanogaster)
      - DLD dimer dehydrogenates dihydrolipoyl (Drosophila melanogaster)
        
        OGDH complex [mitochondrial matrix] (Drosophila melanogaster)
        
        OGDH dimer [mitochondrial matrix] (Drosophila melanogaster)
        
        alpha-ketoglutarate dehydrogenase E1 holoenzyme [mitochondrial matrix] (Drosophila melanogaster)
        
        Homologues of OGDH [mitochondrial matrix] (Drosophila melanogaster)
        
        Ogdh2 [mitochondrial matrix] (Drosophila melanogaster)
      - DLST transfers succinyl to CoA (Drosophila melanogaster)
        
        OGDH complex [mitochondrial matrix] (Drosophila melanogaster)
        
        OGDH dimer [mitochondrial matrix] (Drosophila melanogaster)
        
        alpha-ketoglutarate dehydrogenase E1 holoenzyme [mitochondrial matrix] (Drosophila melanogaster)
        
        Homologues of OGDH [mitochondrial matrix] (Drosophila melanogaster)
        
        Ogdh2 [mitochondrial matrix] (Drosophila melanogaster)
      - OGDH dimer decarboxylates 2-OG (Drosophila melanogaster)
        
        OGDH complex [mitochondrial matrix] (Drosophila melanogaster)
        
        OGDH dimer [mitochondrial matrix] (Drosophila melanogaster)
        
        alpha-ketoglutarate dehydrogenase E1 holoenzyme [mitochondrial matrix] (Drosophila melanogaster)
        
        Homologues of OGDH [mitochondrial matrix] (Drosophila melanogaster)
        
        Ogdh2 [mitochondrial matrix] (Drosophila melanogaster)
        
        OGDH dimer [mitochondrial matrix] (Drosophila melanogaster)
        
        alpha-ketoglutarate dehydrogenase E1 holoenzyme [mitochondrial matrix] (Drosophila melanogaster)
        
        Homologues of OGDH [mitochondrial matrix] (Drosophila melanogaster)
        
        Ogdh2 [mitochondrial matrix] (Drosophila melanogaster)
- Metabolism of amino acids and derivatives (Drosophila melanogaster)
  - Glyoxylate metabolism and glycine degradation (Drosophila melanogaster)
    - Glycine degradation (Drosophila melanogaster)
      - DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate (Drosophila melanogaster)
        
        OGDH complex [mitochondrial matrix] (Drosophila melanogaster)
        
        OGDH dimer [mitochondrial matrix] (Drosophila melanogaster)
        
        alpha-ketoglutarate dehydrogenase E1 holoenzyme [mitochondrial matrix] (Drosophila melanogaster)
        
        Homologues of OGDH [mitochondrial matrix] (Drosophila melanogaster)
        
        Ogdh2 [mitochondrial matrix] (Drosophila melanogaster)

External Reference Information

External Reference

UniProt:Q95T35

Gene Names

Ogdh2

Reference Genes

BioGPS Gene:317974 Ogdh2

ENSEMBL:FBgn0035240

FlyBase:FBgn0035240

Monarch:317974 Ogdh2

NCBI Gene:317974 Ogdh2

UCSC:Q95T35 Ogdh2

Reference Transcript

Other Identifiers

147988_at

147989_at

153043_at

1640732_s_at

317974

GO:0004591

GO:0005739

GO:0005759

GO:0006091

GO:0006096

GO:0006099

GO:0016491

GO:0016624

GO:0030976

GO:0045252

GO:0046872

GO:0055086

GO:0120551

GO:1901135

Participates

as a member of

Homologues of OGDH [mitochondrial matrix] (Drosophila melanogaster)

Inferred From

OGDH [mitochondrial matrix] (Homo sapiens)

Cross References

RefSeq

NP_001027100.1, NP_001027102.1

FlyBase

FBgn0035240

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