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dup [nucleoplasm]
Stable Identifier
R-DME-68536
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
nucleoplasm
Synonyms
CDT1, Q7JVY2
Locations in the PathwayBrowser
Expand all
Cell Cycle (Drosophila melanogaster)
Cell Cycle, Mitotic (Drosophila melanogaster)
Mitotic G1 phase and G1/S transition (Drosophila melanogaster)
G1/S Transition (Drosophila melanogaster)
Activation of the pre-replicative complex (Drosophila melanogaster)
CDT1 binds geminin (Drosophila melanogaster)
CDT1:GMNN [nucleoplasm] (Drosophila melanogaster)
dup [nucleoplasm] (Drosophila melanogaster)
dup [nucleoplasm] (Drosophila melanogaster)
Cdt1 is displaced from the pre-replicative complex (Drosophila melanogaster)
MCM10:pre-replicative complex [nucleoplasm] (Drosophila melanogaster)
pre-replicative complex [nucleoplasm] (Drosophila melanogaster)
CDT1:CDC6:ORC:origin complex [nucleoplasm] (Drosophila melanogaster)
dup [nucleoplasm] (Drosophila melanogaster)
dup [nucleoplasm] (Drosophila melanogaster)
Mcm10 associates with the pre-replicative complex, stabilizing Mcm2-7 (Drosophila melanogaster)
MCM10:pre-replicative complex [nucleoplasm] (Drosophila melanogaster)
pre-replicative complex [nucleoplasm] (Drosophila melanogaster)
CDT1:CDC6:ORC:origin complex [nucleoplasm] (Drosophila melanogaster)
dup [nucleoplasm] (Drosophila melanogaster)
pre-replicative complex [nucleoplasm] (Drosophila melanogaster)
CDT1:CDC6:ORC:origin complex [nucleoplasm] (Drosophila melanogaster)
dup [nucleoplasm] (Drosophila melanogaster)
S Phase (Drosophila melanogaster)
Synthesis of DNA (Drosophila melanogaster)
Switching of origins to a post-replicative state (Drosophila melanogaster)
CDT1 binds geminin (Drosophila melanogaster)
CDT1:GMNN [nucleoplasm] (Drosophila melanogaster)
dup [nucleoplasm] (Drosophila melanogaster)
dup [nucleoplasm] (Drosophila melanogaster)
Orc1 removal from chromatin (Drosophila melanogaster)
Orc1 is phosphorylated by cyclin A/CDK2 (Drosophila melanogaster)
pre-replicative complex (Orc1-minus) [nucleoplasm] (Drosophila melanogaster)
dup [nucleoplasm] (Drosophila melanogaster)
pre-replicative complex [nucleoplasm] (Drosophila melanogaster)
CDT1:CDC6:ORC:origin complex [nucleoplasm] (Drosophila melanogaster)
dup [nucleoplasm] (Drosophila melanogaster)
DNA Replication (Drosophila melanogaster)
DNA Replication Pre-Initiation (Drosophila melanogaster)
Activation of the pre-replicative complex (Drosophila melanogaster)
CDT1 binds geminin (Drosophila melanogaster)
CDT1:GMNN [nucleoplasm] (Drosophila melanogaster)
dup [nucleoplasm] (Drosophila melanogaster)
dup [nucleoplasm] (Drosophila melanogaster)
Cdt1 is displaced from the pre-replicative complex (Drosophila melanogaster)
MCM10:pre-replicative complex [nucleoplasm] (Drosophila melanogaster)
pre-replicative complex [nucleoplasm] (Drosophila melanogaster)
CDT1:CDC6:ORC:origin complex [nucleoplasm] (Drosophila melanogaster)
dup [nucleoplasm] (Drosophila melanogaster)
dup [nucleoplasm] (Drosophila melanogaster)
Mcm10 associates with the pre-replicative complex, stabilizing Mcm2-7 (Drosophila melanogaster)
MCM10:pre-replicative complex [nucleoplasm] (Drosophila melanogaster)
pre-replicative complex [nucleoplasm] (Drosophila melanogaster)
CDT1:CDC6:ORC:origin complex [nucleoplasm] (Drosophila melanogaster)
dup [nucleoplasm] (Drosophila melanogaster)
pre-replicative complex [nucleoplasm] (Drosophila melanogaster)
CDT1:CDC6:ORC:origin complex [nucleoplasm] (Drosophila melanogaster)
dup [nucleoplasm] (Drosophila melanogaster)
Assembly of the pre-replicative complex (Drosophila melanogaster)
The geminin component of geminin:Cdt1 complexes is ubiquitinated, releasing Cdt1 (Drosophila melanogaster)
CDT1:GMNN [nucleoplasm] (Drosophila melanogaster)
dup [nucleoplasm] (Drosophila melanogaster)
dup [nucleoplasm] (Drosophila melanogaster)
Synthesis of DNA (Drosophila melanogaster)
Switching of origins to a post-replicative state (Drosophila melanogaster)
CDT1 binds geminin (Drosophila melanogaster)
CDT1:GMNN [nucleoplasm] (Drosophila melanogaster)
dup [nucleoplasm] (Drosophila melanogaster)
dup [nucleoplasm] (Drosophila melanogaster)
Orc1 removal from chromatin (Drosophila melanogaster)
Orc1 is phosphorylated by cyclin A/CDK2 (Drosophila melanogaster)
pre-replicative complex (Orc1-minus) [nucleoplasm] (Drosophila melanogaster)
dup [nucleoplasm] (Drosophila melanogaster)
pre-replicative complex [nucleoplasm] (Drosophila melanogaster)
CDT1:CDC6:ORC:origin complex [nucleoplasm] (Drosophila melanogaster)
dup [nucleoplasm] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:Q7JVY2
Gene Names
dup
Reference Genes
BioGPS Gene:47121 dup
ENSEMBL:FBgn0000996
FlyBase:FBgn0000996
KEGG:dme:Dmel_CG8171 dup
Monarch:47121 dup
NCBI Gene:47121 dup
UCSC:Q7JVY2 dup
Reference Transcript
RefSeq:NM_001299522.1 dup
RefSeq:NM_080139.5 dup
Other Identifiers
147246_at
1624994_at
47121
GO:0000076
GO:0000278
GO:0003677
GO:0005515
GO:0005634
GO:0005657
GO:0005737
GO:0006260
GO:0007304
GO:0007307
GO:0022414
GO:0030174
GO:0042023
GO:0042065
GO:0065003
GO:0070182
GO:0071163
Participates
as a component of
pre-replicative complex (Orc1-minus) [nucleoplasm] (Drosophila melanogaster)
CDT1:GMNN [nucleoplasm] (Drosophila melanogaster)
CDT1:CDC6:ORC:origin complex [nucleoplasm] (Drosophila melanogaster)
as an output of
The geminin component of geminin:Cdt1 complexes is ubiquitinated, releasing Cdt1 (Drosophila melanogaster)
Cdt1 is displaced from the pre-replicative complex (Drosophila melanogaster)
as an input of
CDT1 binds geminin (Drosophila melanogaster)
Inferred From
CDT1 [nucleoplasm]
(Homo sapiens)
Cross References
RefSeq
NP_001286451.1
,
NP_524878.1
FlyBase
FBgn0000996
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q7JX41
2
geminin [nucleoplasm]
(R-DME-68585)
geminin [nucleoplasm]
(R-DME-113554)
0.547
2
UniProt:Q9VIE6
1
MCM10 [nucleoplasm]
(R-DME-68403)
0.524
2
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