Reactome | omd [nucleoplasm]

omd [nucleoplasm]

Stable Identifier

R-DME-6807418

Type

Protein [EntityWithAccessionedSequence]

Species

Drosophila melanogaster

Compartment

nucleoplasm

Synonyms

INTS5, Q9VFS6

Locations in the PathwayBrowser

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Gene expression (Transcription) (Drosophila melanogaster)

- RNA Polymerase II Transcription (Drosophila melanogaster)
  - RNA polymerase II transcribes snRNA genes (Drosophila melanogaster)
    - CBCAP complex binds 7-methylguanosine cap of snRNA (Drosophila melanogaster)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:CBCAP:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Drosophila melanogaster)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Drosophila melanogaster)
        
        Integrator [nucleoplasm] (Drosophila melanogaster)
        
        omd [nucleoplasm] (Drosophila melanogaster)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Drosophila melanogaster)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Drosophila melanogaster)
        
        Integrator [nucleoplasm] (Drosophila melanogaster)
        
        omd [nucleoplasm] (Drosophila melanogaster)
    - Integrator complex processes the 3' end of snRNA (Drosophila melanogaster)
      - Integrator [nucleoplasm] (Drosophila melanogaster)
        
        omd [nucleoplasm] (Drosophila melanogaster)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:CBCAP:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Drosophila melanogaster)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Drosophila melanogaster)
        
        Integrator [nucleoplasm] (Drosophila melanogaster)
        
        omd [nucleoplasm] (Drosophila melanogaster)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:Initiation factors:snRNA gene [nucleoplasm] (Drosophila melanogaster)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Drosophila melanogaster)
        
        Integrator [nucleoplasm] (Drosophila melanogaster)
        
        omd [nucleoplasm] (Drosophila melanogaster)
    - Pre-snRNA is elongated and capped with 7-methylguanosine (Drosophila melanogaster)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Drosophila melanogaster)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Drosophila melanogaster)
        
        Integrator [nucleoplasm] (Drosophila melanogaster)
        
        omd [nucleoplasm] (Drosophila melanogaster)
      - RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Drosophila melanogaster)
        
        RNA polymerase II (phospho-Ser5,7 CTD):RDRP1A,B:RDRP2:RPAP2:Integrator:LEC [nucleoplasm] (Drosophila melanogaster)
        
        Integrator [nucleoplasm] (Drosophila melanogaster)
        
        omd [nucleoplasm] (Drosophila melanogaster)
    - Pre-snRNA transcript initiation, Integrator binding, LEC binding (Drosophila melanogaster)
      - Integrator [nucleoplasm] (Drosophila melanogaster)
        
        omd [nucleoplasm] (Drosophila melanogaster)
      - RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Drosophila melanogaster)
        
        RNA polymerase II (phospho-Ser5,7 CTD):RDRP1A,B:RDRP2:RPAP2:Integrator:LEC [nucleoplasm] (Drosophila melanogaster)
        
        Integrator [nucleoplasm] (Drosophila melanogaster)
        
        omd [nucleoplasm] (Drosophila melanogaster)

External Reference Information

External Reference

UniProt:Q9VFS6

Gene Names

omd

Reference Genes

BioGPS Gene:41674 omd

ENSEMBL:FBgn0038168

Flybase:FBgn0038168

KEGG Gene (Drosophila melanogaster):Dmel_CG9591 omd

Monarch:41674 omd

NCBI Gene:41674 omd

UCSC:Q9VFS6 omd

Reference Transcript

Other Identifiers

141693_at

1629613_at

41674

GO:0003677

GO:0005634

GO:0005635

GO:0005737

GO:0005829

GO:0010628

GO:0016020

GO:0016073

GO:0023052

GO:0030154

GO:0030514

GO:0031965

GO:0032039

GO:0034472

GO:0043226

GO:0045666

GO:0048856

Participates

as a component of

Integrator [nucleoplasm] (Drosophila melanogaster)

Inferred From

INTS5 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_001262543.1, NP_001262542.1, NP_650303.1

Flybase

FBgn0038168

PRO

Q9VFS6