Reactome | Sras [cytosol]

Sras [cytosol]

Stable Identifier

R-DME-6782807

Type

Protein [EntityWithAccessionedSequence]

Species

Drosophila melanogaster

Compartment

cytosol

Synonyms

PolyUb-RCE1, Q9U1H8

Locations in the PathwayBrowser

Expand all

Metabolism of proteins (Drosophila melanogaster)

- Post-translational protein modification (Drosophila melanogaster)
  - Deubiquitination (Drosophila melanogaster)
    - Ub-specific processing proteases (Drosophila melanogaster)
      - USP17 deubiquitinates RCE1, CDC25A, DDX58, IFIH1 (Drosophila melanogaster)
        
        USP17:PolyUb-RCE1, PolyUb-CDC25A, PolyUb-DDX58, PolyUb-IFIH1 [cytosol] (Drosophila melanogaster)
        
        PolyUb-RCE1, PolyUb-CDC25A, PolyUb-DDX58, PolyUb-IFIH1 [cytosol] (Drosophila melanogaster)
        
        Sras [cytosol] (Drosophila melanogaster)

External Reference Information

External Reference

UniProt:Q9U1H8

Gene Names

Sras

Reference Genes

BioGPS Gene:44002 Sras

ENSEMBL:FBgn0029121

FlyBase:FBgn0029121

KEGG:dme:Dmel_CG4852 Sras

Monarch:44002 Sras

NCBI Gene:44002 Sras

UCSC:Q9U1H8 Sras

Reference Transcript

RefSeq:NM_079934.3 Sras

Other Identifiers

155164_at

1623918_at

44002

GO:0004175

GO:0004222

GO:0005783

GO:0005789

GO:0006508

GO:0008233

GO:0016020

GO:0016787

GO:0051604

GO:0071586

GO:0080120

Participates

as a member of

PolyUb-RCE1, PolyUb-CDC25A, PolyUb-DDX58, PolyUb-IFIH1 [cytosol] (Drosophila melanogaster)

Other forms of this molecule

Sras [cytosol]

Sras [endoplasmic reticulum membrane]

Inferred From

PolyUb-RCE1 [cytosol] (Homo sapiens)

Modified Residues

Name

ubiquitinylated lysine (PolyUb [cytosol]) at unknown position

Modification

PolyUb [cytosol]

PsiMod Name

ubiquitinylated lysine [MOD:01148]

PsiMod Definition

A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a ubiquitin.

Cross References

RefSeq

NP_524673.3

ENSEMBL

FBgn0029121, FBpp0076791, FBtr0077083

IntEnz

3.4.26.1

FlyBase

FBgn0029121

PRO

Q9U1H8

Interactors (16)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q2PDR0	1	Dpm3 [endoplasmic reticulum membrane] (R-DME-162825)	0.488	2
UniProt:A1A6N7 A1A6N7			0.488	2
IntAct:EBI-26744520 SELG			0.488	2
UniProt:Q7JRF1 Q7JRF1			0.488	2
UniProt:Q9VKU1 Q9VKU1			0.488	2
UniProt:O77434 O77434			0.488	2
UniProt:Q8INY3	4	ninaD [platelet alpha granule membrane] (R-DME-114687-5) ninaD [phagocytic vesicle] (R-DME-1236835-5) ninaD [specific granule membrane] (R-DME-6806151-5) ninaD [plasma membrane] (R-DME-51645-5)	0.488	2
UniProt:Q8IQM1	1	Dmel\CG32847 [endoplasmic reticulum membrane] (R-DME-975990-2)	0.488	2
UniProt:Q9VYX8 Q9VYX8			0.488	2
UniProt:Q7JZI2 Q7JZI2			0.488	2
UniProt:B5X533 B5X533			0.488	2
UniProt:A4UZ69 A4UZ69			0.488	2
UniProt:Q8IPG2 Q8IPG2			0.488	2
UniProt:E1NZB7 E1NZB7			0.488	2
UniProt:Q9VNX9 Q9VNX9			0.488	2
UniProt:Q9W0N6	2	Vti1a [trans-Golgi network membrane] (R-DME-6813927) Vti1a [Golgi membrane] (R-DME-6811035)	0.488	2

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