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MSH6 [nucleoplasm]
Stable Identifier
R-DME-5357528
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
nucleoplasm
Synonyms
Q9VUM0
Locations in the PathwayBrowser
Expand all
DNA Repair (Drosophila melanogaster)
Mismatch Repair (Drosophila melanogaster)
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) (Drosophila melanogaster)
EXO1 interacts with MSH2:MSH6 (MutSalpha) and MLH1:PMS2 (MutLalpha) (Drosophila melanogaster)
EXO1:MLH1:PMS2:MSH2:MSH6:ATP:PCNA:DNA containing 1-2 base mismatch and single strand incision [nucleoplasm] (Drosophila melanogaster)
MSH2:MSH6:ATP [nucleoplasm] (Drosophila melanogaster)
MSH6 [nucleoplasm] (Drosophila melanogaster)
MLH1:PMS2:MSH2:MSH6:ATP:PCNA:DNA containing 1-2 base mismatch and single strand incision [nucleoplasm] (Drosophila melanogaster)
MSH2:MSH6:ATP [nucleoplasm] (Drosophila melanogaster)
MSH6 [nucleoplasm] (Drosophila melanogaster)
Formation of MSH2:MSH6 Complex (Drosophila melanogaster)
MSH2:MSH6:ADP [nucleoplasm] (Drosophila melanogaster)
MSH6 [nucleoplasm] (Drosophila melanogaster)
MSH6 [nucleoplasm] (Drosophila melanogaster)
MLH1:PMS2 makes single strand incision near 1-2 base mismatch (Drosophila melanogaster)
MLH1:PMS2:MSH2:MSH6:ATP:PCNA:DNA containing 1-2 base mismatch [nucleoplasm] (Drosophila melanogaster)
MSH2:MSH6:ATP [nucleoplasm] (Drosophila melanogaster)
MSH6 [nucleoplasm] (Drosophila melanogaster)
MLH1:PMS2:MSH2:MSH6:ATP:PCNA:DNA containing 1-2 base mismatch and single strand incision [nucleoplasm] (Drosophila melanogaster)
MSH2:MSH6:ATP [nucleoplasm] (Drosophila melanogaster)
MSH6 [nucleoplasm] (Drosophila melanogaster)
MSH2:MSH6 binds 1 base mismatch or 1-2 base insertion/deletion loop (Drosophila melanogaster)
MSH2:MSH6:ADP [nucleoplasm] (Drosophila melanogaster)
MSH6 [nucleoplasm] (Drosophila melanogaster)
MSH2:MSH6:ADP:DNA containing 1-2 base mismatch [nucleoplasm] (Drosophila melanogaster)
MSH2:MSH6:ADP [nucleoplasm] (Drosophila melanogaster)
MSH6 [nucleoplasm] (Drosophila melanogaster)
MSH2:MSH6 exchanges ADP for ATP (Drosophila melanogaster)
MSH2:MSH6:ADP:DNA containing 1-2 base mismatch [nucleoplasm] (Drosophila melanogaster)
MSH2:MSH6:ADP [nucleoplasm] (Drosophila melanogaster)
MSH6 [nucleoplasm] (Drosophila melanogaster)
MSH2:MSH6:ATP:DNA containing 1-2 base mismatch [nucleoplasm] (Drosophila melanogaster)
MSH2:MSH6:ATP [nucleoplasm] (Drosophila melanogaster)
MSH6 [nucleoplasm] (Drosophila melanogaster)
MSH2:MSH6 recruits MLH1:PMS2 to mismatch and interacts with PCNA (Drosophila melanogaster)
MLH1:PMS2:MSH2:MSH6:ATP:PCNA:DNA containing 1-2 base mismatch [nucleoplasm] (Drosophila melanogaster)
MSH2:MSH6:ATP [nucleoplasm] (Drosophila melanogaster)
MSH6 [nucleoplasm] (Drosophila melanogaster)
MSH2:MSH6:ATP:DNA containing 1-2 base mismatch [nucleoplasm] (Drosophila melanogaster)
MSH2:MSH6:ATP [nucleoplasm] (Drosophila melanogaster)
MSH6 [nucleoplasm] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:Q9VUM0
Reference Genes
BioGPS Gene:39654
ENSEMBL:FBgn0036486
FlyBase:FBgn0036486
KEGG:dme:Dmel_CG7003
Monarch:39654
NCBI Gene:39654
UCSC:Q9VUM0
Reference Transcript
RefSeq:NM_140498.2
Other Identifiers
148795_at
1637163_at
39654
GO:0000166
GO:0000710
GO:0003677
GO:0005524
GO:0005634
GO:0006281
GO:0006298
GO:0006974
GO:0016787
GO:0016887
GO:0022414
GO:0030983
GO:0032301
GO:0140664
Participates
as a component of
MSH2:MSH6:ATP [nucleoplasm] (Drosophila melanogaster)
MSH2:MSH6:ADP [nucleoplasm] (Drosophila melanogaster)
as an input of
Formation of MSH2:MSH6 Complex (Drosophila melanogaster)
Inferred From
MSH6 [nucleoplasm]
(Homo sapiens)
Cross References
RefSeq
NP_648755.1
ENSEMBL
FBpp0075399
,
FBgn0036486
,
FBtr0075646
FlyBase
FBgn0036486
PRO
Q9VUM0
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:M9NFI9 M9NFI9
0.462
2
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