Reactome | Sym [nucleoplasm]

Sym [nucleoplasm]

Stable Identifier

R-DME-4615988

Type

Protein [EntityWithAccessionedSequence]

Species

Drosophila melanogaster

Compartment

nucleoplasm

Synonyms

SYMPK, Q8MSU4

Locations in the PathwayBrowser

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Gene expression (Transcription) (Drosophila melanogaster)

- RNA Polymerase II Transcription (Drosophila melanogaster)
  - RNA Polymerase II Transcription Termination (Drosophila melanogaster)
    - Cleavage of Intronless Pre-mRNA at 3'-end (Drosophila melanogaster)
      - intronless pre-mRNA cleavage complex [nucleoplasm] (Drosophila melanogaster)
        
        CstF:CPSF:capped intronless pre-mRNA:CBC complex [nucleoplasm] (Drosophila melanogaster)
        
        CPSF:capped intronless pre-mRNA:CBC complex [nucleoplasm] (Drosophila melanogaster)
        
        CPSF [nucleoplasm] (Drosophila melanogaster)
        
        Sym [nucleoplasm] (Drosophila melanogaster)
      - upstream mRNA fragment:CPSF:PAP:PABPN1 complex [nucleoplasm] (Drosophila melanogaster)
        
        CPSF [nucleoplasm] (Drosophila melanogaster)
        
        Sym [nucleoplasm] (Drosophila melanogaster)

External Reference Information

External Reference

UniProt:Q8MSU4

Gene Names

Sym

Reference Genes

BioGPS Gene:40709 Sym

ENSEMBL:FBgn0037371

FlyBase:FBgn0037371

KEGG:dme:Dmel_CG2097 Sym

Monarch:40709 Sym

NCBI Gene:40709 Sym

UCSC:Q8MSU4 Sym

Reference Transcript

RefSeq:NM_141323.2 Sym

Other Identifiers

155136_at

1630794_at

40709

GO:0003723

GO:0005515

GO:0005634

GO:0005847

GO:0006397

GO:0006398

GO:0016071

GO:0035363

GO:0061689

GO:0180010

Participates

as an input of

Formation of the core cleavage and polyadenylation complex (Drosophila melanogaster)

as a component of

Inferred From

SYMPK [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_649580.1

ENSEMBL

FBtr0078723, FBgn0037371, FBpp0078372

FlyBase

FBgn0037371

PRO

Q8MSU4

PDB

6NPW, 4IMJ, 4IMI, 3GS3, 4YGX

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O61307 TENM			0.462	2
UniProt:Q9VH81	2	PpD3 [nucleoplasm] (R-DME-5683410) PpD3 [cytosol] (R-DME-5675402)	0.462	2

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