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phospho-Tis11 [cytosol]
Stable Identifier
R-DME-450496
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
cytosol
Synonyms
p-S60,S186-ZFP36, P47980
Locations in the PathwayBrowser
Expand all
Metabolism of RNA (Drosophila melanogaster)
Regulation of mRNA stability by proteins that bind AU-rich elements (Drosophila melanogaster)
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA (Drosophila melanogaster)
MK2 phosphorylates ZFP36 (Tristetraproline, TTP) (Drosophila melanogaster)
Phosphorylated TTP:mRNA Complex [cytosol] (Drosophila melanogaster)
phospho-Tis11 [cytosol] (Drosophila melanogaster)
p-S60,S186-ZFP36 (Tristetraproline, TTP) binds 14-3-3beta (Drosophila melanogaster)
Phosphorylated TTP:mRNA Complex [cytosol] (Drosophila melanogaster)
phospho-Tis11 [cytosol] (Drosophila melanogaster)
Phosphorylated TTP:mRNA:14-3-3 Complex [cytosol] (Drosophila melanogaster)
Phosphorylated TTP:mRNA Complex [cytosol] (Drosophila melanogaster)
phospho-Tis11 [cytosol] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:P47980
Gene Names
Tis11
Reference Genes
BioGPS Gene:32222 Tis11
CTD Gene:32222 Tis11
ENSEMBL:FBgn0011837
FlyBase:FBgn0011837
KEGG:dme:Dmel_CG4070 Tis11
Monarch:32222 Tis11
NCBI Gene:32222 Tis11
UCSC:P47980 Tis11
Reference Transcript
RefSeq:NM_001272561.2 Tis11
RefSeq:NM_167333.4 Tis11
RefSeq:NM_078586.5 Tis11
Other Identifiers
142170_at
151486_at
1623863_a_at
1634610_at
32222
GO:0003677
GO:0003729
GO:0003730
GO:0005634
GO:0005829
GO:0008270
GO:0010629
GO:0031047
GO:0035194
GO:0035925
GO:0046872
GO:0061158
GO:1900153
Participates
as a component of
Phosphorylated TTP:mRNA Complex [cytosol] (Drosophila melanogaster)
Other forms of this molecule
Tis11 [cytosol]
phospho-Tis11 [cytosol]
Tis11 [cytosol]
phospho-Tis11 [cytosol]
Inferred From
p-S60,S186-ZFP36 [cytosol]
(Homo sapiens)
Modified Residues
Name
O-phospho-L-serine at 60 (in Homo sapiens)
Coordinate
60
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 186 (in Homo sapiens)
Coordinate
186
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Cross References
RefSeq
NP_001259490.1
,
NP_511141.2
,
NP_727633.2
ENSEMBL
FBgn0011837
,
FBtr0345165
,
FBtr0073683
,
FBpp0073516
,
FBpp0305898
,
FBtr0333756
,
FBpp0311375
FlyBase
FBgn0011837
PRO
P47980
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