Reactome | mAChR-B [plasma membrane]

mAChR-B [plasma membrane]

Stable Identifier

R-DME-390693-2

Type

Protein [EntityWithAccessionedSequence]

Species

Drosophila melanogaster

Compartment

plasma membrane

Synonyms

CHRM4, Q9VHW1

Locations in the PathwayBrowser

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Signal Transduction (Drosophila melanogaster)

- Signaling by GPCR (Drosophila melanogaster)
  - GPCR downstream signalling (Drosophila melanogaster)
    - G alpha (i) signalling events (Drosophila melanogaster)
      - Liganded Gi-activating GPCR acts as a GEF for Gi (Drosophila melanogaster)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Drosophila melanogaster)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Drosophila melanogaster)
        
        CHRM2,CHRM4:AcCho [plasma membrane] (Drosophila melanogaster)
        
        CHRM2,CHRM4 [plasma membrane] (Drosophila melanogaster)
        
        Homologues of CHRM4 [plasma membrane] (Drosophila melanogaster)
        
        mAChR-B [plasma membrane] (Drosophila melanogaster)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Drosophila melanogaster)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Drosophila melanogaster)
        
        CHRM2,CHRM4:AcCho [plasma membrane] (Drosophila melanogaster)
        
        CHRM2,CHRM4 [plasma membrane] (Drosophila melanogaster)
        
        Homologues of CHRM4 [plasma membrane] (Drosophila melanogaster)
        
        mAChR-B [plasma membrane] (Drosophila melanogaster)
  - GPCR ligand binding (Drosophila melanogaster)
    - Class A/1 (Rhodopsin-like receptors) (Drosophila melanogaster)
      - Amine ligand-binding receptors (Drosophila melanogaster)
        
        Muscarinic acetylcholine receptors (Drosophila melanogaster)
        
        CHRM2,4 bind acetylcholine (Drosophila melanogaster)
        
        CHRM2,CHRM4 [plasma membrane] (Drosophila melanogaster)
        
        Homologues of CHRM4 [plasma membrane] (Drosophila melanogaster)
        
        mAChR-B [plasma membrane] (Drosophila melanogaster)
        
        CHRM2,CHRM4:AcCho [plasma membrane] (Drosophila melanogaster)
        
        CHRM2,CHRM4 [plasma membrane] (Drosophila melanogaster)
        
        Homologues of CHRM4 [plasma membrane] (Drosophila melanogaster)
        
        mAChR-B [plasma membrane] (Drosophila melanogaster)
        
        CHRM4 binds CHRM4 antagonists (Drosophila melanogaster)
        
        CHRM4:CHRM4 antagonists [plasma membrane] (Drosophila melanogaster)
        
        Homologues of CHRM4 [plasma membrane] (Drosophila melanogaster)
        
        mAChR-B [plasma membrane] (Drosophila melanogaster)
        
        Homologues of CHRM4 [plasma membrane] (Drosophila melanogaster)
        
        mAChR-B [plasma membrane] (Drosophila melanogaster)

External Reference Information

External Reference

UniProt:Q9VHW1

Gene Names

mAChR-B

Reference Genes

BioGPS Gene:40955 mAChR-B

ENSEMBL:FBgn0037546

FlyBase:FBgn0037546

Monarch:40955 mAChR-B

NCBI Gene:40955 mAChR-B

UCSC:Q9VHW1 mAChR-B

Reference Transcript

RefSeq:NM_141507.2 mAChR-B

Other Identifiers

149472_at

1639186_at

40955

GO:0004930

GO:0004993

GO:0005886

GO:0007165

GO:0007186

GO:0007187

GO:0007197

GO:0007213

GO:0007268

GO:0008227

GO:0016020

GO:0016907

GO:0030425

GO:0045202

Participates

as a member of

Homologues of CHRM4 [plasma membrane] (Drosophila melanogaster)

Other forms of this molecule

mAChR-B [clathrin-coated endocytic vesicle membrane]

mAChR-B [plasma membrane]

Inferred From

CHRM4 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

NP_649764.1

FlyBase

FBgn0037546

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