Reactome | Gcn5 [nucleoplasm]

Gcn5 [nucleoplasm]

Stable Identifier

R-DME-352430

Type

Protein [EntityWithAccessionedSequence]

Species

Drosophila melanogaster

Compartment

nucleoplasm

Synonyms

KAT2B, Q9VTZ1

Locations in the PathwayBrowser

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Gene expression (Transcription) (Drosophila melanogaster)

- RNA Polymerase II Transcription (Drosophila melanogaster)
  - Generic Transcription Pathway (Drosophila melanogaster)
    - FOXO-mediated transcription (Drosophila melanogaster)
      - Regulation of FOXO transcriptional activity by acetylation (Drosophila melanogaster)
        
        KAT2B,EP300 acetylate FOXO3 under oxidative stress (Drosophila melanogaster)
        
        KAT2B,(EP300) [nucleoplasm] (Drosophila melanogaster)
        
        Gcn5 [nucleoplasm] (Drosophila melanogaster)
    - Transcriptional regulation by RUNX1 (Drosophila melanogaster)
      - RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function (Drosophila melanogaster)
        
        Core MLL complex methylates H3K4Me2-Nucleosome at the GP1BA gene promoter (Drosophila melanogaster)
        
        H3K4me2-Nucleosome:GP1BA gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Drosophila melanogaster)
        
        RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Drosophila melanogaster)
        
        Gcn5 [nucleoplasm] (Drosophila melanogaster)
        
        H3K4me3-Nucleosome:GP1BA gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Drosophila melanogaster)
        
        RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Drosophila melanogaster)
        
        Gcn5 [nucleoplasm] (Drosophila melanogaster)
        
        Core MLL complex methylates H3K4Me2-Nucleosome at the ITGA2B gene promoter (Drosophila melanogaster)
        
        H3K4me2-Nucleosome:ITGA2B gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Drosophila melanogaster)
        
        RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Drosophila melanogaster)
        
        Gcn5 [nucleoplasm] (Drosophila melanogaster)
        
        H3K4me3-Nucleosome:ITGA2B gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Drosophila melanogaster)
        
        RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Drosophila melanogaster)
        
        Gcn5 [nucleoplasm] (Drosophila melanogaster)
        
        Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter (Drosophila melanogaster)
        
        H3K4me2-Nucleosome:MIR27A gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Drosophila melanogaster)
        
        RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Drosophila melanogaster)
        
        Gcn5 [nucleoplasm] (Drosophila melanogaster)
        
        H3K4me3-Nucleosome:MIR27A gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Drosophila melanogaster)
        
        RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Drosophila melanogaster)
        
        Gcn5 [nucleoplasm] (Drosophila melanogaster)
        
        RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Drosophila melanogaster)
        
        Gcn5 [nucleoplasm] (Drosophila melanogaster)
        
        Core MLL complex methylates H3K4Me2-Nucleosome at the THBS1 gene promoter (Drosophila melanogaster)
        
        H3K4me2-Nucleosome:THBS1 gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Drosophila melanogaster)
        
        RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Drosophila melanogaster)
        
        Gcn5 [nucleoplasm] (Drosophila melanogaster)
        
        H3K4me3-Nucleosome:THBS1 gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Drosophila melanogaster)
        
        RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Drosophila melanogaster)
        
        Gcn5 [nucleoplasm] (Drosophila melanogaster)

External Reference Information

External Reference

UniProt:Q9VTZ1

Gene Names

Gcn5

Reference Genes

BioGPS Gene:39431 Gcn5

ENSEMBL:FBgn0020388

FlyBase:FBgn0020388

KEGG:dme:Dmel_CG4107 Gcn5

Monarch:39431 Gcn5

NCBI Gene:39431 Gcn5

UCSC:Q9VTZ1 Gcn5

Reference Transcript

RefSeq:NM_140329.3 Gcn5

Other Identifiers

152381_at

1627246_at

39431

GO:0000124

GO:0003682

GO:0003824

GO:0004402

GO:0005515

GO:0005634

GO:0005654

GO:0005694

GO:0005700

GO:0005703

GO:0005737

GO:0005813

GO:0005815

GO:0005856

GO:0006325

GO:0006338

GO:0006355

GO:0010468

GO:0010484

GO:0010485

GO:0016740

GO:0016746

GO:0016747

GO:0043992

GO:0045944

GO:0070775

GO:0140096

GO:0140672

Participates

as a member of

as a component of

Other forms of this molecule

Gcn5 [nucleoplasm]

Inferred From

PCAF [nucleoplasm] (Homo sapiens)

KAT2B [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_648586.2

FlyBase

FBgn0020388

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