Further phosphorylation of ARM by SGG

Stable Identifier
R-DME-209109
Type
Reaction [transition]
Species
Drosophila melanogaster
Compartment
cytosol
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Further phosphorylation of ARM by SGG
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Phosphorylation of bound Armadillo (ARM) at Ser44, Ser48, and Thr52 by Shaggy (SGG) occurs.

Literature References
PubMed ID Title Journal Year
14966281 Biochemical characterization of the Drosophila wingless signaling pathway based on RNA interference

Matsubayashi, H, Sese, S, Lee, JS, Shirakawa, T, Iwatsubo, T, Tomita, T, Yanagawa, S

Mol Cell Biol 2004
12000790 Axin-mediated CKI phosphorylation of beta-catenin at Ser 45: a molecular switch for the Wnt pathway

Amit, S, Hatzubai, A, Birman, Y, Andersen, JS, Ben-Shushan, E, Mann, M, Ben-Neriah, Y, Alkalay, I

Genes Dev 2002
11955436 Control of beta-catenin phosphorylation/degradation by a dual-kinase mechanism

Liu, C, Li, Y, Semenov, M, Han, C, Baeg, GH, Tan, Y, Zhang, Z, Lin, X, He, X

Cell 2002
11927557 Casein kinase I phosphorylates the Armadillo protein and induces its degradation in Drosophila

Yanagawa, S, Matsuda, Y, Lee, JS, Matsubayashi, H, Sese, S, Kadowaki, T, Ishimoto, A

EMBO J 2002
Participants
Input
Output
Participant Of
hasEvent
Catalyst Activity
Catalyst Activity
Title
protein serine/threonine kinase activity of Phospho ARM:Phospho (3 sites) AXN:Phospho (6 sites) APC:PP2A:CKIalpha:DCO:SGG [cytosol]
Physical Entity
Phospho ARM:Phospho (3 sites) AXN:Phospho (6 sites) APC:PP2A:CKIalpha:DCO:SGG [cytosol]
Activity
protein serine/threonine kinase activity (0004674)
Authored
Williams, MG  (2006-07-26)
Reviewed
Nusse, R  (2008-01-19)
Created
Williams, MG  (2006-06-28)