Further phosphorylation of ARM by SGG

Stable Identifier
R-DME-209109
Type
Reaction [transition]
Species
Drosophila melanogaster
Compartment
cytosol
ReviewStatus
5/5
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Further phosphorylation of ARM by SGG
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Phosphorylation of bound Armadillo (ARM) at Ser44, Ser48, and Thr52 by Shaggy (SGG) occurs.
Literature References
PubMed ID Title Journal Year
12000790 Axin-mediated CKI phosphorylation of beta-catenin at Ser 45: a molecular switch for the Wnt pathway

Amit, S, Hatzubai, A, Birman, Y, Andersen, JS, Ben-Shushan, E, Mann, M, Ben-Neriah, Y, Alkalay, I

Genes Dev 2002
14966281 Biochemical characterization of the Drosophila wingless signaling pathway based on RNA interference

Matsubayashi, H, Sese, S, Lee, JS, Shirakawa, T, Iwatsubo, T, Tomita, T, Yanagawa, S

Mol Cell Biol 2004
11955436 Control of beta-catenin phosphorylation/degradation by a dual-kinase mechanism

Liu, C, Li, Y, Semenov, M, Han, C, Baeg, GH, Tan, Y, Zhang, Z, Lin, X, He, X

Cell 2002
11927557 Casein kinase I phosphorylates the Armadillo protein and induces its degradation in Drosophila

Yanagawa, S, Matsuda, Y, Lee, JS, Matsubayashi, H, Sese, S, Kadowaki, T, Ishimoto, A

EMBO J 2002
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Catalyst Activity

protein serine/threonine kinase activity of Phospho ARM:Phospho (3 sites) AXN:Phospho (6 sites) APC:PP2A:CKIalpha:DCO:SGG [cytosol]

Physical Entity
Phospho ARM:Phospho (3 sites) AXN:Phospho (6 sites) APC:PP2A:CKIalpha:DCO:SGG [cytosol] (Drosophila melanogaster)
Activity
protein serine/threonine kinase activity (GO:0004674)
Authored
Williams, MG  (2006-07-26)
Reviewed
Nusse, R  (2008-01-19)
Created
Williams, MG  (2006-06-28)
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