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UEV1A [cytosol]
Stable Identifier
R-DME-206024
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Drosophila signaling pathways (Drosophila melanogaster)
Imd pathway (Drosophila melanogaster)
Activation of the IkappaB kinase complex, KEY:IRD5 dimer:KEY (Drosophila melanogaster)
Activated TAK1 kinase is autophosphorylated (Drosophila melanogaster)
UEV1A:BEN:IAP2:UBI-P63E:TAB2:Phospho TAK1 [cytosol] (Drosophila melanogaster)
UEV1A [cytosol] (Drosophila melanogaster)
UEV1A:BEN:IAP2:UBI-P63E:TAB2:TAK1 [cytosol] (Drosophila melanogaster)
UEV1A [cytosol] (Drosophila melanogaster)
Activated phosphorylated TAK1 kinase phosphorylates and activates IRD5 (Drosophila melanogaster)
UEV1A:BEN:IAP2:UBI-P63E:TAB2:Phospho TAK1 [cytosol] (Drosophila melanogaster)
UEV1A [cytosol] (Drosophila melanogaster)
HEP is phosphorylated and activated by Phospho TAK1:TAB2 kinase complex (Drosophila melanogaster)
UEV1A:BEN:IAP2:UBI-P63E:TAB2:Phospho TAK1 [cytosol] (Drosophila melanogaster)
UEV1A [cytosol] (Drosophila melanogaster)
IAP2:BEN:UEV1A E3 ligase complex auto-ubiquitinates (Drosophila melanogaster)
UEV1A:BEN:IAP2 [cytosol] (Drosophila melanogaster)
UEV1A [cytosol] (Drosophila melanogaster)
UEV1A:BEN:IAP2:UBI-P63E [cytosol] (Drosophila melanogaster)
UEV1A [cytosol] (Drosophila melanogaster)
TAB2 binds to ubiquitinated IAP2:BEN:UEV1A E3 ligase complex and activates TAK1 kinase (Drosophila melanogaster)
UEV1A:BEN:IAP2:UBI-P63E [cytosol] (Drosophila melanogaster)
UEV1A [cytosol] (Drosophila melanogaster)
UEV1A:BEN:IAP2:UBI-P63E:TAB2:TAK1 [cytosol] (Drosophila melanogaster)
UEV1A [cytosol] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:Q9VRL1 Uev1A
Gene Names
Uev1A, CG10640, Dmel_CG10640
Reference Genes
BioGPS Gene:38613 Uev1A
KEGG:dme:Dmel_CG10640 Uev1A
Monarch:38613 Uev1A
NCBI Gene:38613 Uev1A
UCSC:Q9VRL1 Uev1A
Reference Transcript
RefSeq:NM_139702.4 Uev1A
RefSeq:NM_001300011.1 Uev1A
Other Identifiers
148216_at
1624782_a_at
38613
GO:0000209
GO:0002376
GO:0005515
GO:0005634
GO:0005829
GO:0006281
GO:0006301
GO:0030335
GO:0031371
GO:0031372
GO:0031624
GO:0043068
GO:0046330
GO:0061057
GO:0070534
GO:1903265
Participates
as a component of
UEV1A:BEN:IAP2 [cytosol] (Drosophila melanogaster)
UEV1A:BEN:IAP2:UBI-P63E [cytosol] (Drosophila melanogaster)
UEV1A:BEN:IAP2:UBI-P63E:TAB2:TAK1 [cytosol] (Drosophila melanogaster)
UEV1A:BEN:IAP2:UBI-P63E:TAB2:Phospho TAK1 [cytosol] (Drosophila melanogaster)
Other forms of this molecule
Uev1A [cytosol]
Uev1A [nucleoplasm]
Uev1A [cytosol]
Cross References
RefSeq
NP_647959.1
,
NP_001286940.1
FlyBase
FBgn0035601
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P21461
2
SIAH2 [cytosol]
(R-DME-374566)
SIAH1 [cytosol]
(R-DME-374563)
0.488
2
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