Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
phospho-p-5Y,S1119-TEK [plasma membrane]
Stable Identifier
R-DME-204772
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
plasma membrane
Synonyms
Q7KT06
Locations in the PathwayBrowser
Expand all
Hemostasis (Drosophila melanogaster)
Cell surface interactions at the vascular wall (Drosophila melanogaster)
Tie2 Signaling (Drosophila melanogaster)
Interaction of SOS-1 to Tie2 bound Grb2 (Drosophila melanogaster)
Grb2 bound to Tie2 [plasma membrane] (Drosophila melanogaster)
ANGPT1:p-5Y,S119-TEK [plasma membrane] (Drosophila melanogaster)
phospho-p-5Y,S1119-TEK [plasma membrane] (Drosophila melanogaster)
SOS-1 bound to Tie2:Grb2 [plasma membrane] (Drosophila melanogaster)
Grb2 bound to Tie2 [plasma membrane] (Drosophila melanogaster)
ANGPT1:p-5Y,S119-TEK [plasma membrane] (Drosophila melanogaster)
phospho-p-5Y,S1119-TEK [plasma membrane] (Drosophila melanogaster)
Interaction of Tie2 and Dok-2 (Drosophila melanogaster)
ANGPT1:p-5Y,S119-TEK [plasma membrane] (Drosophila melanogaster)
phospho-p-5Y,S1119-TEK [plasma membrane] (Drosophila melanogaster)
Tie2 and Dok-2 complex [plasma membrane] (Drosophila melanogaster)
ANGPT1:p-5Y,S119-TEK [plasma membrane] (Drosophila melanogaster)
phospho-p-5Y,S1119-TEK [plasma membrane] (Drosophila melanogaster)
Interaction of Tie2 and Grb2 (Drosophila melanogaster)
ANGPT1:p-5Y,S119-TEK [plasma membrane] (Drosophila melanogaster)
phospho-p-5Y,S1119-TEK [plasma membrane] (Drosophila melanogaster)
Grb2 bound to Tie2 [plasma membrane] (Drosophila melanogaster)
ANGPT1:p-5Y,S119-TEK [plasma membrane] (Drosophila melanogaster)
phospho-p-5Y,S1119-TEK [plasma membrane] (Drosophila melanogaster)
Interaction of Tie2 and Shc1 (Drosophila melanogaster)
ANGPT1:p-5Y,S119-TEK [plasma membrane] (Drosophila melanogaster)
phospho-p-5Y,S1119-TEK [plasma membrane] (Drosophila melanogaster)
ANGPT1:p-5Y,S119-TEK:SHC1 [plasma membrane] (Drosophila melanogaster)
ANGPT1:p-5Y,S119-TEK [plasma membrane] (Drosophila melanogaster)
phospho-p-5Y,S1119-TEK [plasma membrane] (Drosophila melanogaster)
Interaction of Tie2 and p85 of PI3K (Drosophila melanogaster)
ANGPT1:p-5Y,S119-TEK [plasma membrane] (Drosophila melanogaster)
phospho-p-5Y,S1119-TEK [plasma membrane] (Drosophila melanogaster)
p85 bound to Tie2 [plasma membrane] (Drosophila melanogaster)
ANGPT1:p-5Y,S119-TEK [plasma membrane] (Drosophila melanogaster)
phospho-p-5Y,S1119-TEK [plasma membrane] (Drosophila melanogaster)
Sos-mediated nucleotide exchange of Ras (Tie2 receptor:Grb2:Sos) (Drosophila melanogaster)
SOS-1 bound to Tie2:Grb2 [plasma membrane] (Drosophila melanogaster)
Grb2 bound to Tie2 [plasma membrane] (Drosophila melanogaster)
ANGPT1:p-5Y,S119-TEK [plasma membrane] (Drosophila melanogaster)
phospho-p-5Y,S1119-TEK [plasma membrane] (Drosophila melanogaster)
Signal Transduction (Drosophila melanogaster)
MAPK family signaling cascades (Drosophila melanogaster)
MAPK1/MAPK3 signaling (Drosophila melanogaster)
RAF/MAP kinase cascade (Drosophila melanogaster)
RAS GEFs promote RAS nucleotide exchange (Drosophila melanogaster)
RAS GEFs [plasma membrane] (Drosophila melanogaster)
SOS-1 bound to Tie2:Grb2 [plasma membrane] (Drosophila melanogaster)
Grb2 bound to Tie2 [plasma membrane] (Drosophila melanogaster)
ANGPT1:p-5Y,S119-TEK [plasma membrane] (Drosophila melanogaster)
phospho-p-5Y,S1119-TEK [plasma membrane] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:Q7KT06
Reference Genes
BioGPS Gene:43875
ENSEMBL:FBgn0011829
FlyBase:FBgn0011829
KEGG:dme:Dmel_CG14396
Monarch:43875
NCBI Gene:43875
UCSC:Q7KT06
Reference Transcript
RefSeq:NM_165359.2
RefSeq:NM_057696.4
RefSeq:NM_165358.2
Other Identifiers
143697_at
146577_at
1622991_s_at
43875
GO:0000166
GO:0001954
GO:0003824
GO:0004672
GO:0004713
GO:0004714
GO:0005178
GO:0005509
GO:0005524
GO:0005886
GO:0006468
GO:0007015
GO:0007169
GO:0009653
GO:0009986
GO:0016020
GO:0016301
GO:0016358
GO:0016740
GO:0022008
GO:0030154
GO:0030424
GO:0030425
GO:0038127
GO:0043235
GO:0046872
GO:0048513
GO:0048856
GO:0050773
GO:0140096
Participates
as a component of
ANGPT1:p-5Y,S119-TEK [plasma membrane] (Drosophila melanogaster)
Other forms of this molecule
RET [plasma membrane]
TEK [plasma membrane]
Inferred From
p-5Y,S1119-TEK [plasma membrane]
(Homo sapiens)
Modified Residues
Name
O4'-phospho-L-tyrosine at 816 (in Homo sapiens)
Coordinate
816
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 992 (in Homo sapiens)
Coordinate
992
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 1102 (in Homo sapiens)
Coordinate
1102
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 1108 (in Homo sapiens)
Coordinate
1108
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O-phospho-L-serine at 1119 (in Homo sapiens)
Coordinate
1119
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O4'-phospho-L-tyrosine at 1113 (in Homo sapiens)
Coordinate
1113
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Cross References
FlyBase
FBgn0011829
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9VMV9 Q9VMV9
0.527
2
© 2026
Reactome
This website requires cookies and the limited processing of your personal data in order to function. By using the site you are agreeing to this as outlined in our
Privacy Notice
.
I agree, dismiss this banner
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text