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phospho-PRAS40 [cytosol]
Stable Identifier
R-DME-200163
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
cytosol
Synonyms
p-S183,S221,T246-AKT1S1, Q7JXA2
Locations in the PathwayBrowser
Expand all
Signal Transduction (Drosophila melanogaster)
Intracellular signaling by second messengers (Drosophila melanogaster)
PIP3 activates AKT signaling (Drosophila melanogaster)
AKT phosphorylates targets in the cytosol (Drosophila melanogaster)
AKT phosphorylates AKT1S1 (PRAS40) (Drosophila melanogaster)
phospho-PRAS40 [cytosol] (Drosophila melanogaster)
MTOR signalling (Drosophila melanogaster)
Phosphorylated AKT1S1 binds YWHAB (Drosophila melanogaster)
p-S183,S221,T246-AKT1S1:YWHAB [lysosomal membrane] (Drosophila melanogaster)
phospho-PRAS40 [cytosol] (Drosophila melanogaster)
phospho-PRAS40 [cytosol] (Drosophila melanogaster)
mTORC1 phosphorylates AKT1S1 (Drosophila melanogaster)
phospho-PRAS40 [cytosol] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:Q7JXA2
Gene Names
PRAS40
Reference Genes
BioGPS Gene:26067067 PRAS40
CTD Gene:26067067 PRAS40
ENSEMBL:FBgn0267824
FlyBase:FBgn0267824
KEGG:dme:Dmel_CG46146 PRAS40
Monarch:26067067 PRAS40
NCBI Gene:26067067 PRAS40
UCSC:Q7JXA2 PRAS40
Reference Transcript
RefSeq:NM_001316420.1 PRAS40
Other Identifiers
147206_at
1637785_at
26067067
GO:0005737
GO:0005829
GO:0007219
GO:0030948
GO:0032007
GO:0046627
GO:0048011
GO:1904262
Participates
as an input of
Phosphorylated AKT1S1 binds YWHAB (Drosophila melanogaster)
as a component of
p-S183,S221,T246-AKT1S1:YWHAB [lysosomal membrane] (Drosophila melanogaster)
as an output of
mTORC1 phosphorylates AKT1S1 (Drosophila melanogaster)
AKT phosphorylates AKT1S1 (PRAS40) (Drosophila melanogaster)
Other forms of this molecule
PRAS40 [nucleoplasm]
phospho-PRAS40 [cytosol]
PRAS40 [cytosol]
Inferred From
p-S183,S221,T246-AKT1S1 [cytosol]
(Homo sapiens)
Modified Residues
Name
O-phospho-L-serine at 183 (in Homo sapiens)
Coordinate
183
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-threonine at 246 (in Homo sapiens)
Coordinate
246
PsiMod Name
O-phospho-L-threonine [MOD:00047]
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Name
O-phospho-L-serine at 221 (in Homo sapiens)
Coordinate
221
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Cross References
RefSeq
NP_001303349.1
FlyBase
FBgn0267824
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