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Cyclin A:Cdk2:p21/p27 complex [nucleoplasm]
Stable Identifier
R-DME-187926
Type
Complex
Species
Drosophila melanogaster
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
Cell Cycle (Drosophila melanogaster)
Cell Cycle Checkpoints (Drosophila melanogaster)
G1/S DNA Damage Checkpoints (Drosophila melanogaster)
p53-Dependent G1/S DNA damage checkpoint (Drosophila melanogaster)
p53-Dependent G1 DNA Damage Response (Drosophila melanogaster)
Inactivation of Cyclin A:Cdk2 complexes by p27/p21 (Drosophila melanogaster)
Cyclin A:Cdk2:p21/p27 complex [nucleoplasm] (Drosophila melanogaster)
Cell Cycle, Mitotic (Drosophila melanogaster)
S Phase (Drosophila melanogaster)
Cyclin A:Cdk2-associated events at S phase entry (Drosophila melanogaster)
Cyclin A:Cdk2 mediated phosphorylation of p27/p21 (Drosophila melanogaster)
Cyclin A:Cdk2:p21/p27 complex [nucleoplasm] (Drosophila melanogaster)
Inactivation of Cyclin A:Cdk2 complexes by p27/p21 (Drosophila melanogaster)
Cyclin A:Cdk2:p21/p27 complex [nucleoplasm] (Drosophila melanogaster)
Cellular responses to stimuli (Drosophila melanogaster)
Cellular responses to stress (Drosophila melanogaster)
Cellular Senescence (Drosophila melanogaster)
DNA Damage/Telomere Stress Induced Senescence (Drosophila melanogaster)
Inactivation of Cyclin A:Cdk2 complexes by p27/p21 (Drosophila melanogaster)
Cyclin A:Cdk2:p21/p27 complex [nucleoplasm] (Drosophila melanogaster)
Senescence-Associated Secretory Phenotype (SASP) (Drosophila melanogaster)
CDKN1A (p21) prevents association of Cyclin A:Cdk2 with Cdh1 (Drosophila melanogaster)
Cyclin A:Cdk2:p21/p27 complex [nucleoplasm] (Drosophila melanogaster)
CDKN1A (p21) prevents phosphorylation of Cdh1 by Cyclin A:Cdk2 (Drosophila melanogaster)
Cyclin A:Cdk2:p21/p27 complex [nucleoplasm] (Drosophila melanogaster)
Gene expression (Transcription) (Drosophila melanogaster)
RNA Polymerase II Transcription (Drosophila melanogaster)
Generic Transcription Pathway (Drosophila melanogaster)
Transcriptional Regulation by TP53 (Drosophila melanogaster)
TP53 Regulates Transcription of Cell Cycle Genes (Drosophila melanogaster)
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest (Drosophila melanogaster)
Inactivation of Cyclin A:Cdk2 complexes by p27/p21 (Drosophila melanogaster)
Cyclin A:Cdk2:p21/p27 complex [nucleoplasm] (Drosophila melanogaster)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
CCNA:CDK2 [nucleoplasm]
(Drosophila melanogaster)
dap [nucleoplasm]
(Drosophila melanogaster)
Participates
as an input of
Cyclin A:Cdk2 mediated phosphorylation of p27/p21 (Drosophila melanogaster)
as an output of
Inactivation of Cyclin A:Cdk2 complexes by p27/p21 (Drosophila melanogaster)
This entity regulates
Negatively
CDKN1A (p21) prevents phosphorylation of Cdh1 by Cyclin A:Cdk2
(Drosophila melanogaster)
CDKN1A (p21) prevents association of Cyclin A:Cdk2 with Cdh1
(Drosophila melanogaster)
Inferred From
Cyclin A:Cdk2:p21/p27 complex [nucleoplasm]
(Homo sapiens)
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