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dap [nucleoplasm]
Stable Identifier
R-DME-182563
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
nucleoplasm
Synonyms
CDKN1B, Q7JNL9
Locations in the PathwayBrowser
Expand all
Cell Cycle (Drosophila melanogaster)
Cell Cycle Checkpoints (Drosophila melanogaster)
G1/S DNA Damage Checkpoints (Drosophila melanogaster)
p53-Dependent G1/S DNA damage checkpoint (Drosophila melanogaster)
p53-Dependent G1 DNA Damage Response (Drosophila melanogaster)
Inactivation of Cyclin A:Cdk2 complexes by p27/p21 (Drosophila melanogaster)
Cyclin A:Cdk2:p21/p27 complex [nucleoplasm] (Drosophila melanogaster)
dap [nucleoplasm] (Drosophila melanogaster)
dap [nucleoplasm] (Drosophila melanogaster)
Inactivation of Cyclin E:Cdk2 complexes by p27/p21 (Drosophila melanogaster)
Cyclin E:CDK2:CDKN1A,CDKN1B [nucleoplasm] (Drosophila melanogaster)
dap [nucleoplasm] (Drosophila melanogaster)
dap [nucleoplasm] (Drosophila melanogaster)
Cell Cycle, Mitotic (Drosophila melanogaster)
Mitotic G1 phase and G1/S transition (Drosophila melanogaster)
G1 Phase (Drosophila melanogaster)
Cyclin D associated events in G1 (Drosophila melanogaster)
CDK4/6:CCND complexes are activated by T-loop phosphorylation of CDK4/6 (Drosophila melanogaster)
CDK4,CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C); CDK4,CDK6:CCND; (CDK4,CDK6:CCND:p-Y88-CDKN1B) [nucleoplasm] (Drosophila melanogaster)
Cyclin D:CDK4,CDK6:CDKN1A,CDKN1B,(CDKN1C) [nucleoplasm] (Drosophila melanogaster)
dap [nucleoplasm] (Drosophila melanogaster)
p-T172-CDK4,p-T177-CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C); p-T172-CDK4,p-T177-CDK6:CCND; (p-T172-CDK4,p-T177-CDK6:CCND:p-Y88-CDKN1B) [nucleoplasm] (Drosophila melanogaster)
p-T172-CDK4,p-T177-CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C) [nucleoplasm] (Drosophila melanogaster)
dap [nucleoplasm] (Drosophila melanogaster)
Cyclin D:CDK4/6 mediated phosphorylation of p107 (RBL1) and dissociation of phosphorylated p107 (p-RBL1) from DP1:E2F4 complex (Drosophila melanogaster)
p-T172-CDK4,p-T177-CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C); p-T172-CDK4,p-T177-CDK6:CCND; (p-T172-CDK4,p-T177-CDK6:CCND:p-Y88-CDKN1B) [nucleoplasm] (Drosophila melanogaster)
p-T172-CDK4,p-T177-CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C) [nucleoplasm] (Drosophila melanogaster)
dap [nucleoplasm] (Drosophila melanogaster)
Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes (Drosophila melanogaster)
p-T172-CDK4,p-T177-CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C); p-T172-CDK4,p-T177-CDK6:CCND; (p-T172-CDK4,p-T177-CDK6:CCND:p-Y88-CDKN1B) [nucleoplasm] (Drosophila melanogaster)
p-T172-CDK4,p-T177-CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C) [nucleoplasm] (Drosophila melanogaster)
dap [nucleoplasm] (Drosophila melanogaster)
Cyclin D:Cdk4/6 mediated phosphorylation of p130 (RBL2) and dissociation of phosphorylated p130 (RBL2) from DP1:E2F4/5 complex (Drosophila melanogaster)
p-T172-CDK4,p-T177-CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C); p-T172-CDK4,p-T177-CDK6:CCND; (p-T172-CDK4,p-T177-CDK6:CCND:p-Y88-CDKN1B) [nucleoplasm] (Drosophila melanogaster)
p-T172-CDK4,p-T177-CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C) [nucleoplasm] (Drosophila melanogaster)
dap [nucleoplasm] (Drosophila melanogaster)
RB1 binds and inhibits E2F1/2/3:DP1/2 complexes (Drosophila melanogaster)
p-T172-CDK4,p-T177-CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C); p-T172-CDK4,p-T177-CDK6:CCND; (p-T172-CDK4,p-T177-CDK6:CCND:p-Y88-CDKN1B) [nucleoplasm] (Drosophila melanogaster)
p-T172-CDK4,p-T177-CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C) [nucleoplasm] (Drosophila melanogaster)
dap [nucleoplasm] (Drosophila melanogaster)
Translocation of CDK4/6:CCND complexes from the cytoplasm to the nucleus (Drosophila melanogaster)
CDK4,CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C); CDK4,CDK6:CCND; (CDK4,CDK6:CCND:p-Y88-CDKN1B) [nucleoplasm] (Drosophila melanogaster)
Cyclin D:CDK4,CDK6:CDKN1A,CDKN1B,(CDKN1C) [nucleoplasm] (Drosophila melanogaster)
dap [nucleoplasm] (Drosophila melanogaster)
G1/S Transition (Drosophila melanogaster)
Cyclin E associated events during G1/S transition (Drosophila melanogaster)
Inactivation of Cyclin E:Cdk2 complexes by p27/p21 (Drosophila melanogaster)
Cyclin E:CDK2:CDKN1A,CDKN1B [nucleoplasm] (Drosophila melanogaster)
dap [nucleoplasm] (Drosophila melanogaster)
dap [nucleoplasm] (Drosophila melanogaster)
SCF(Skp2)-mediated degradation of p27/p21 (Drosophila melanogaster)
Cyclin E/A:Cdk2-mediated phosphorylation of p27/p21 (Drosophila melanogaster)
Cyclin E/A:p-T160-CDK2:CDKN1A,CDKN1B [nucleoplasm] (Drosophila melanogaster)
dap [nucleoplasm] (Drosophila melanogaster)
Translocation of p27 to the nucleoplasm (Drosophila melanogaster)
dap [nucleoplasm] (Drosophila melanogaster)
S Phase (Drosophila melanogaster)
Cyclin A:Cdk2-associated events at S phase entry (Drosophila melanogaster)
Cyclin A:Cdk2 mediated phosphorylation of p27/p21 (Drosophila melanogaster)
Cyclin A:Cdk2:p21/p27 complex [nucleoplasm] (Drosophila melanogaster)
dap [nucleoplasm] (Drosophila melanogaster)
Inactivation of Cyclin A:Cdk2 complexes by p27/p21 (Drosophila melanogaster)
Cyclin A:Cdk2:p21/p27 complex [nucleoplasm] (Drosophila melanogaster)
dap [nucleoplasm] (Drosophila melanogaster)
dap [nucleoplasm] (Drosophila melanogaster)
SCF(Skp2)-mediated degradation of p27/p21 (Drosophila melanogaster)
Cyclin E/A:Cdk2-mediated phosphorylation of p27/p21 (Drosophila melanogaster)
Cyclin E/A:p-T160-CDK2:CDKN1A,CDKN1B [nucleoplasm] (Drosophila melanogaster)
dap [nucleoplasm] (Drosophila melanogaster)
Translocation of p27 to the nucleoplasm (Drosophila melanogaster)
dap [nucleoplasm] (Drosophila melanogaster)
Cellular responses to stimuli (Drosophila melanogaster)
Cellular responses to stress (Drosophila melanogaster)
Cellular Senescence (Drosophila melanogaster)
DNA Damage/Telomere Stress Induced Senescence (Drosophila melanogaster)
Inactivation of Cyclin A:Cdk2 complexes by p27/p21 (Drosophila melanogaster)
Cyclin A:Cdk2:p21/p27 complex [nucleoplasm] (Drosophila melanogaster)
dap [nucleoplasm] (Drosophila melanogaster)
dap [nucleoplasm] (Drosophila melanogaster)
Inactivation of Cyclin E:Cdk2 complexes by p27/p21 (Drosophila melanogaster)
Cyclin E:CDK2:CDKN1A,CDKN1B [nucleoplasm] (Drosophila melanogaster)
dap [nucleoplasm] (Drosophila melanogaster)
dap [nucleoplasm] (Drosophila melanogaster)
Senescence-Associated Secretory Phenotype (SASP) (Drosophila melanogaster)
CDKN1A (p21) prevents association of Cyclin A:Cdk2 with Cdh1 (Drosophila melanogaster)
Cyclin A:Cdk2:p21/p27 complex [nucleoplasm] (Drosophila melanogaster)
dap [nucleoplasm] (Drosophila melanogaster)
CDKN1A (p21) prevents phosphorylation of Cdh1 by Cyclin A:Cdk2 (Drosophila melanogaster)
Cyclin A:Cdk2:p21/p27 complex [nucleoplasm] (Drosophila melanogaster)
dap [nucleoplasm] (Drosophila melanogaster)
Gene expression (Transcription) (Drosophila melanogaster)
RNA Polymerase II Transcription (Drosophila melanogaster)
Generic Transcription Pathway (Drosophila melanogaster)
Transcriptional Regulation by TP53 (Drosophila melanogaster)
TP53 Regulates Transcription of Cell Cycle Genes (Drosophila melanogaster)
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest (Drosophila melanogaster)
Inactivation of Cyclin A:Cdk2 complexes by p27/p21 (Drosophila melanogaster)
Cyclin A:Cdk2:p21/p27 complex [nucleoplasm] (Drosophila melanogaster)
dap [nucleoplasm] (Drosophila melanogaster)
dap [nucleoplasm] (Drosophila melanogaster)
Inactivation of Cyclin E:Cdk2 complexes by p27/p21 (Drosophila melanogaster)
Cyclin E:CDK2:CDKN1A,CDKN1B [nucleoplasm] (Drosophila melanogaster)
dap [nucleoplasm] (Drosophila melanogaster)
dap [nucleoplasm] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:Q7JNL9
Gene Names
dap
Reference Genes
BioGPS Gene:36001 dap
ENSEMBL:FBgn0010316
FlyBase:FBgn0010316
KEGG:dme:Dmel_CG1772 dap
Monarch:36001 dap
NCBI Gene:36001 dap
UCSC:Q7JNL9 dap
Reference Transcript
RefSeq:NM_057600.6 dap
Other Identifiers
141388_at
1625199_s_at
36001
GO:0000278
GO:0004860
GO:0004861
GO:0005515
GO:0005634
GO:0005654
GO:0005739
GO:0006279
GO:0007294
GO:0007419
GO:0007488
GO:0022414
GO:0035220
GO:0035308
GO:0045035
GO:0045930
GO:0048477
GO:0048856
GO:0051726
GO:0051729
GO:0098772
GO:2000134
Participates
as an input of
Inactivation of Cyclin A:Cdk2 complexes by p27/p21 (Drosophila melanogaster)
Inactivation of Cyclin E:Cdk2 complexes by p27/p21 (Drosophila melanogaster)
as a component of
Cyclin A:Cdk2:p21/p27 complex [nucleoplasm] (Drosophila melanogaster)
Cyclin E:CDK2:CDKN1A,CDKN1B [nucleoplasm] (Drosophila melanogaster)
Cyclin E/A:p-T160-CDK2:CDKN1A,CDKN1B [nucleoplasm] (Drosophila melanogaster)
Cyclin D:CDK4,CDK6:CDKN1A,CDKN1B,(CDKN1C) [nucleoplasm] (Drosophila melanogaster)
p-T172-CDK4,p-T177-CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C) [nucleoplasm] (Drosophila melanogaster)
as an output of
Translocation of p27 to the nucleoplasm (Drosophila melanogaster)
Other forms of this molecule
phospho-dap [cytosol]
phospho-dap [nucleoplasm]
phospho-dap [cytosol]
phospho-dap [nucleoplasm]
phospho-dap [cytosol]
dap [cytosol]
dap [cytosol]
phospho-dap [cytosol]
dap [nucleoplasm]
phospho-dap [nucleoplasm]
Inferred From
CDKN1A,CDKN1B [nucleoplasm]
(Homo sapiens)
CDKN1A,CDKN1B,(CDKN1C) [nucleoplasm]
(Homo sapiens)
CDKN1B [nucleoplasm]
(Homo sapiens)
Cross References
RefSeq
NP_476948.1
FlyBase
FBgn0010316
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