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vap [cytosol]
Stable Identifier
R-DME-186833
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
cytosol
Synonyms
RASA1, Q8IR23
Locations in the PathwayBrowser
Expand all
Developmental Biology (Drosophila melanogaster)
Nervous system development (Drosophila melanogaster)
Axon guidance (Drosophila melanogaster)
EPH-Ephrin signaling (Drosophila melanogaster)
EPHB-mediated forward signaling (Drosophila melanogaster)
Ras:GTP binds p120-RasGAP (Drosophila melanogaster)
p-EPHBs:EFNBs:RASA1 [plasma membrane] (Drosophila melanogaster)
vap [cytosol] (Drosophila melanogaster)
p-EPHBs:EFNBs:RASA1:HRAS:GTP [plasma membrane] (Drosophila melanogaster)
p-EPHBs:EFNBs:RASA1 [plasma membrane] (Drosophila melanogaster)
vap [cytosol] (Drosophila melanogaster)
p120-RasGAP activates GTP hydrolysis on RAS, inactivating it (Drosophila melanogaster)
p-EPHBs:EFNBs:RASA1:HRAS:GDP [plasma membrane] (Drosophila melanogaster)
p-EPHBs:EFNBs:RASA1 [plasma membrane] (Drosophila melanogaster)
vap [cytosol] (Drosophila melanogaster)
p-EPHBs:EFNBs:RASA1:HRAS:GTP [plasma membrane] (Drosophila melanogaster)
p-EPHBs:EFNBs:RASA1 [plasma membrane] (Drosophila melanogaster)
vap [cytosol] (Drosophila melanogaster)
vap [cytosol] (Drosophila melanogaster)
Signal Transduction (Drosophila melanogaster)
MAPK family signaling cascades (Drosophila melanogaster)
MAPK1/MAPK3 signaling (Drosophila melanogaster)
RAF/MAP kinase cascade (Drosophila melanogaster)
Regulation of RAS by GAPs (Drosophila melanogaster)
RAS GAPs bind RAS:GTP (Drosophila melanogaster)
RAS GAPs [cytosol] (Drosophila melanogaster)
vap [cytosol] (Drosophila melanogaster)
p21 RAS:GTP:RAS GAPs [plasma membrane] (Drosophila melanogaster)
RAS GAPs [cytosol] (Drosophila melanogaster)
vap [cytosol] (Drosophila melanogaster)
RAS GAPs stimulate RAS GTPase activity (Drosophila melanogaster)
RAS GAPs [cytosol] (Drosophila melanogaster)
vap [cytosol] (Drosophila melanogaster)
p21 RAS:GTP:RAS GAPs [plasma membrane] (Drosophila melanogaster)
RAS GAPs [cytosol] (Drosophila melanogaster)
vap [cytosol] (Drosophila melanogaster)
Signaling by Non-Receptor Tyrosine Kinases (Drosophila melanogaster)
Signaling by PTK6 (Drosophila melanogaster)
PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases (Drosophila melanogaster)
ARHGAP35 binds RASA1 (Drosophila melanogaster)
p-Y1105-ARHGAP35:RASA1 [cytosol] (Drosophila melanogaster)
vap [cytosol] (Drosophila melanogaster)
vap [cytosol] (Drosophila melanogaster)
RASA1 binds RAS:GTP (Drosophila melanogaster)
p21 RAS:GTP:RASA1 [plasma membrane] (Drosophila melanogaster)
vap [cytosol] (Drosophila melanogaster)
vap [cytosol] (Drosophila melanogaster)
RASA1 stimulates RAS GTPase activity (Drosophila melanogaster)
p-Y1105-ARHGAP35:RASA1 [cytosol] (Drosophila melanogaster)
vap [cytosol] (Drosophila melanogaster)
p21 RAS:GTP:RASA1 [plasma membrane] (Drosophila melanogaster)
vap [cytosol] (Drosophila melanogaster)
vap [cytosol] (Drosophila melanogaster)
Signaling by Receptor Tyrosine Kinases (Drosophila melanogaster)
Signaling by PDGF (Drosophila melanogaster)
Downstream signal transduction (Drosophila melanogaster)
GAP binds to PDGF-beta receptors only (Drosophila melanogaster)
Phospho-beta receptor homodimer:GAP [plasma membrane] (Drosophila melanogaster)
vap [cytosol] (Drosophila melanogaster)
vap [cytosol] (Drosophila melanogaster)
Signaling by VEGF (Drosophila melanogaster)
VEGFA-VEGFR2 Pathway (Drosophila melanogaster)
VEGFR2 mediated cell proliferation (Drosophila melanogaster)
p-SPHK1 phosphorylates sphingosine to sphingosine 1-phosphate (Drosophila melanogaster)
RASA1:p21 RAS:GTP:SPG [plasma membrane] (Drosophila melanogaster)
vap [cytosol] (Drosophila melanogaster)
vap [cytosol] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:Q8IR23
Gene Names
vap
Reference Genes
BioGPS Gene:32569 vap
ENSEMBL:FBgn0003969
FlyBase:FBgn0003969
KEGG:dme:Dmel_CG9209 vap
Monarch:32569 vap
NCBI Gene:32569 vap
UCSC:Q8IR23 vap
Reference Transcript
RefSeq:NM_167480.2 vap
RefSeq:NM_001298386.1 vap
RefSeq:NM_001298385.1 vap
RefSeq:NM_206759.2 vap
RefSeq:NM_167481.3 vap
RefSeq:NM_078637.3 vap
Other Identifiers
141759_at
1629859_s_at
32569
GO:0001784
GO:0002009
GO:0005096
GO:0005104
GO:0005122
GO:0005515
GO:0005829
GO:0007165
GO:0009653
GO:0016319
GO:0030100
GO:0040037
GO:0043087
GO:0043547
GO:0046580
GO:0048149
GO:0048468
GO:0048856
GO:0098772
GO:0120177
Participates
as a component of
p-EPHBs:EFNBs:RASA1 [plasma membrane] (Drosophila melanogaster)
RASA1:p21 RAS:GTP:SPG [plasma membrane] (Drosophila melanogaster)
Phospho-beta receptor homodimer:GAP [plasma membrane] (Drosophila melanogaster)
p-Y1105-ARHGAP35:RASA1 [cytosol] (Drosophila melanogaster)
p21 RAS:GTP:RASA1 [plasma membrane] (Drosophila melanogaster)
as an output of
p-SPHK1 phosphorylates sphingosine to sphingosine 1-phosphate (Drosophila melanogaster)
RASA1 stimulates RAS GTPase activity (Drosophila melanogaster)
as an input of
GAP binds to PDGF-beta receptors only (Drosophila melanogaster)
ARHGAP35 binds RASA1 (Drosophila melanogaster)
RASA1 binds RAS:GTP (Drosophila melanogaster)
as a member of
RAS GAPs [cytosol] (Drosophila melanogaster)
Inferred From
RASA1 [cytosol]
(Homo sapiens)
Cross References
ENSEMBL
FBtr0074143
,
FBtr0074142
,
FBtr0340415
,
FBtr0074141
,
FBtr0074140
,
FBtr0340416
,
FBpp0073945
,
FBpp0309361
,
FBpp0073946
,
FBpp0309362
,
FBpp0089147
,
FBpp0089148
,
FBgn0003969
FlyBase
FBgn0003969
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