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14-3-3zeta [cytosol]
Stable Identifier
R-DME-1445116
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
cytosol
Synonyms
YWHAQ, P29310
Locations in the PathwayBrowser
Expand all
Cell Cycle (Drosophila melanogaster)
Cell Cycle Checkpoints (Drosophila melanogaster)
G2/M Checkpoints (Drosophila melanogaster)
G2/M DNA damage checkpoint (Drosophila melanogaster)
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex (Drosophila melanogaster)
Association of p-S216-CDC25C with 14-3-3 proteins (Drosophila melanogaster)
14-3-3 dimer [cytosol] (Drosophila melanogaster)
YWHAQ dimer [cytosol] (Drosophila melanogaster)
14-3-3zeta [cytosol] (Drosophila melanogaster)
p-S216-CDC25C:14-3-3 protein complex [cytosol] (Drosophila melanogaster)
14-3-3 dimer [cytosol] (Drosophila melanogaster)
YWHAQ dimer [cytosol] (Drosophila melanogaster)
14-3-3zeta [cytosol] (Drosophila melanogaster)
Gene expression (Transcription) (Drosophila melanogaster)
RNA Polymerase II Transcription (Drosophila melanogaster)
Generic Transcription Pathway (Drosophila melanogaster)
FOXO-mediated transcription (Drosophila melanogaster)
Regulation of localization of FOXO transcription factors (Drosophila melanogaster)
14-3-3 proteins bind AKT-phosphorylated FOXO1 (Drosophila melanogaster)
YWHAZ dimer,YWHAQ dimer,YWHAG dimer,YWHAB dimer [cytosol] (Drosophila melanogaster)
YWHAQ dimer [cytosol] (Drosophila melanogaster)
14-3-3zeta [cytosol] (Drosophila melanogaster)
p-T24,S256,S319-FOXO1:YWHAZ,YWHAQ,YWHAG,YWHAB [cytosol] (Drosophila melanogaster)
YWHAZ dimer,YWHAQ dimer,YWHAG dimer,YWHAB dimer [cytosol] (Drosophila melanogaster)
YWHAQ dimer [cytosol] (Drosophila melanogaster)
14-3-3zeta [cytosol] (Drosophila melanogaster)
14-3-3 proteins bind AKT-phosphorylated FOXO3 (Drosophila melanogaster)
YWHAZ dimer,YWHAQ dimer,SFN dimer [cytosol] (Drosophila melanogaster)
YWHAQ dimer [cytosol] (Drosophila melanogaster)
14-3-3zeta [cytosol] (Drosophila melanogaster)
p-T32,S253,S315-FOXO3:YWHAZ,YWHAQ,SFN [cytosol] (Drosophila melanogaster)
YWHAZ dimer,YWHAQ dimer,SFN dimer [cytosol] (Drosophila melanogaster)
YWHAQ dimer [cytosol] (Drosophila melanogaster)
14-3-3zeta [cytosol] (Drosophila melanogaster)
14-3-3 proteins bind AKT-phosphorylated FOXO4 (Drosophila melanogaster)
YWHAQ dimer [cytosol] (Drosophila melanogaster)
14-3-3zeta [cytosol] (Drosophila melanogaster)
p-T32,S197,S262-FOXO4:YWHAZ dimer [cytosol] (Drosophila melanogaster)
YWHAQ dimer [cytosol] (Drosophila melanogaster)
14-3-3zeta [cytosol] (Drosophila melanogaster)
Transcriptional Regulation by TP53 (Drosophila melanogaster)
TP53 Regulates Metabolic Genes (Drosophila melanogaster)
DDIT4 binds 14-3-3 dimer (Drosophila melanogaster)
14-3-3 dimer [cytosol] (Drosophila melanogaster)
YWHAQ dimer [cytosol] (Drosophila melanogaster)
14-3-3zeta [cytosol] (Drosophila melanogaster)
DDIT4:14-3-3 dimer [cytosol] (Drosophila melanogaster)
14-3-3 dimer [cytosol] (Drosophila melanogaster)
YWHAQ dimer [cytosol] (Drosophila melanogaster)
14-3-3zeta [cytosol] (Drosophila melanogaster)
p-S939,T1462-TSC2 binding to 14-3-3 dimer is negatively regulated by DDIT4 (Drosophila melanogaster)
14-3-3 dimer [cytosol] (Drosophila melanogaster)
YWHAQ dimer [cytosol] (Drosophila melanogaster)
14-3-3zeta [cytosol] (Drosophila melanogaster)
DDIT4:14-3-3 dimer [cytosol] (Drosophila melanogaster)
14-3-3 dimer [cytosol] (Drosophila melanogaster)
YWHAQ dimer [cytosol] (Drosophila melanogaster)
14-3-3zeta [cytosol] (Drosophila melanogaster)
p-S939,T1462-TSC2:14-3-3 dimer [cytosol] (Drosophila melanogaster)
14-3-3 dimer [cytosol] (Drosophila melanogaster)
YWHAQ dimer [cytosol] (Drosophila melanogaster)
14-3-3zeta [cytosol] (Drosophila melanogaster)
Hemostasis (Drosophila melanogaster)
Platelet activation, signaling and aggregation (Drosophila melanogaster)
GP1b-IX-V activation signalling (Drosophila melanogaster)
14-3-3-zeta binds Raf1 (Drosophila melanogaster)
14-3-3-zeta:Raf1 [cytosol] (Drosophila melanogaster)
YWHAQ dimer [cytosol] (Drosophila melanogaster)
14-3-3zeta [cytosol] (Drosophila melanogaster)
YWHAQ dimer [cytosol] (Drosophila melanogaster)
14-3-3zeta [cytosol] (Drosophila melanogaster)
Signal Transduction (Drosophila melanogaster)
Signaling by NOTCH (Drosophila melanogaster)
Signaling by NOTCH4 (Drosophila melanogaster)
NOTCH4 Activation and Transmission of Signal to the Nucleus (Drosophila melanogaster)
NICD4 traffics to the nucleus (Drosophila melanogaster)
p-4S-NICD4:YWHAZ dimer [cytosol] (Drosophila melanogaster)
YWHAQ dimer [cytosol] (Drosophila melanogaster)
14-3-3zeta [cytosol] (Drosophila melanogaster)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Drosophila melanogaster)
Signaling by Rho GTPases (Drosophila melanogaster)
RHO GTPase Effectors (Drosophila melanogaster)
RHO GTPases activate PKNs (Drosophila melanogaster)
Association of p-S216-CDC25C with 14-3-3 proteins (Drosophila melanogaster)
14-3-3 dimer [cytosol] (Drosophila melanogaster)
YWHAQ dimer [cytosol] (Drosophila melanogaster)
14-3-3zeta [cytosol] (Drosophila melanogaster)
p-S216-CDC25C:14-3-3 protein complex [cytosol] (Drosophila melanogaster)
14-3-3 dimer [cytosol] (Drosophila melanogaster)
YWHAQ dimer [cytosol] (Drosophila melanogaster)
14-3-3zeta [cytosol] (Drosophila melanogaster)
Signaling by WNT (Drosophila melanogaster)
TCF dependent signaling in response to WNT (Drosophila melanogaster)
Deactivation of the beta-catenin transactivating complex (Drosophila melanogaster)
YWHAZ and XPO1 mediate the nuclear export of beta-catenin (Drosophila melanogaster)
XPO1:YWHAZ:p-S20-CBY1:CTNNB1 [cytosol] (Drosophila melanogaster)
14-3-3zeta [cytosol] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:P29310 14-3-3zeta
Gene Names
14-3-3zeta, 14-3-3, 14-3-3EZ, leo, THAP, CG17870
Chain
chain:1-248
Reference Genes
BioGPS Gene:36059 14-3-3zeta
CTD Gene:36059 14-3-3zeta
KEGG Gene (Drosophila melanogaster):Dmel_CG17870 14-3-3zeta
Monarch:36059 14-3-3zeta
NCBI Gene:36059 14-3-3zeta
Reference Transcript
RefSeq:NM_165741.3 14-3-3zeta
RefSeq:NM_165740.3 14-3-3zeta
RefSeq:NM_165742.2 14-3-3zeta
RefSeq:NM_206070.2 14-3-3zeta
RefSeq:NM_001273916.1 14-3-3zeta
RefSeq:NM_001014515.2 14-3-3zeta
RefSeq:NM_165745.3 14-3-3zeta
RefSeq:NM_165743.3 14-3-3zeta
RefSeq:NM_165744.3 14-3-3zeta
RefSeq:NM_057537.4 14-3-3zeta
RefSeq:NM_001014516.2 14-3-3zeta
RefSeq:NM_001273917.1 14-3-3zeta
Other Identifiers
153924_at
1625148_s_at
36059
GO:0000278
GO:0001223
GO:0005515
GO:0005634
GO:0005635
GO:0005737
GO:0005768
GO:0005769
GO:0005829
GO:0005886
GO:0006351
GO:0006355
GO:0006457
GO:0007010
GO:0007059
GO:0007163
GO:0007165
GO:0007294
GO:0007399
GO:0007460
GO:0007611
GO:0008103
GO:0008104
GO:0008134
GO:0016020
GO:0022414
GO:0023052
GO:0030154
GO:0031410
GO:0031965
GO:0035332
GO:0040040
GO:0042803
GO:0042994
GO:0043226
GO:0045172
GO:0045448
GO:0046579
GO:0046982
GO:0048856
GO:0050821
GO:0050877
GO:0051220
GO:0120176
GO:0140313
Participates
as a component of
XPO1:YWHAZ:p-S20-CBY1:CTNNB1 [cytosol] (Drosophila melanogaster)
YWHAQ dimer [cytosol] (Drosophila melanogaster)
Other forms of this molecule
14-3-3zeta [cytosol]
14-3-3zeta [nucleoplasm]
14-3-3zeta [cytosol]
14-3-3zeta [cytosol]
14-3-3zeta [cytosol]
14-3-3zeta [cytosol]
Inferred From
YWHAZ [cytosol]
(Homo sapiens)
YWHAQ [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_995792.1
,
NP_001260845.1
,
NP_724886.1
,
NP_724884.1
,
NP_724887.2
,
NP_724888.2
,
NP_476885.2
,
NP_724885.1
,
NP_001014516.1
,
NP_001014515.1
,
NP_001260846.1
,
NP_724889.2
Flybase
FBgn0004907
PRO
P29310
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q8IPH9 SLOB
0.66
5
UniProt:Q9VQ93 GOLP3
0.508
3
UniProt:Q9VS36 TO6BL
0.488
2
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