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14-3-3zeta [cytosol]
Stable Identifier
R-DME-48888
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
cytosol
Synonyms
YWHAB, P29310
Locations in the PathwayBrowser
Expand all
Cell Cycle (Drosophila melanogaster)
Cell Cycle Checkpoints (Drosophila melanogaster)
G2/M Checkpoints (Drosophila melanogaster)
G2/M DNA damage checkpoint (Drosophila melanogaster)
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex (Drosophila melanogaster)
Association of p-S216-CDC25C with 14-3-3 proteins (Drosophila melanogaster)
14-3-3 dimer [cytosol] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
14-3-3zeta [cytosol] (Drosophila melanogaster)
p-S216-CDC25C:14-3-3 protein complex [cytosol] (Drosophila melanogaster)
14-3-3 dimer [cytosol] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
14-3-3zeta [cytosol] (Drosophila melanogaster)
Gene expression (Transcription) (Drosophila melanogaster)
RNA Polymerase II Transcription (Drosophila melanogaster)
Generic Transcription Pathway (Drosophila melanogaster)
FOXO-mediated transcription (Drosophila melanogaster)
Regulation of localization of FOXO transcription factors (Drosophila melanogaster)
14-3-3 proteins bind AKT-phosphorylated FOXO1 (Drosophila melanogaster)
YWHAZ dimer,YWHAQ dimer,YWHAG dimer,YWHAB dimer [cytosol] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
14-3-3zeta [cytosol] (Drosophila melanogaster)
p-T24,S256,S319-FOXO1:YWHAZ,YWHAQ,YWHAG,YWHAB [cytosol] (Drosophila melanogaster)
YWHAZ dimer,YWHAQ dimer,YWHAG dimer,YWHAB dimer [cytosol] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
14-3-3zeta [cytosol] (Drosophila melanogaster)
Transcriptional Regulation by TP53 (Drosophila melanogaster)
TP53 Regulates Metabolic Genes (Drosophila melanogaster)
DDIT4 binds 14-3-3 dimer (Drosophila melanogaster)
14-3-3 dimer [cytosol] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
14-3-3zeta [cytosol] (Drosophila melanogaster)
DDIT4:14-3-3 dimer [cytosol] (Drosophila melanogaster)
14-3-3 dimer [cytosol] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
14-3-3zeta [cytosol] (Drosophila melanogaster)
p-S939,T1462-TSC2 binding to 14-3-3 dimer is negatively regulated by DDIT4 (Drosophila melanogaster)
14-3-3 dimer [cytosol] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
14-3-3zeta [cytosol] (Drosophila melanogaster)
DDIT4:14-3-3 dimer [cytosol] (Drosophila melanogaster)
14-3-3 dimer [cytosol] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
14-3-3zeta [cytosol] (Drosophila melanogaster)
p-S939,T1462-TSC2:14-3-3 dimer [cytosol] (Drosophila melanogaster)
14-3-3 dimer [cytosol] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
14-3-3zeta [cytosol] (Drosophila melanogaster)
Immune System (Drosophila melanogaster)
Adaptive Immune System (Drosophila melanogaster)
Rap1 signalling (Drosophila melanogaster)
14-3-3 proteins beta and zeta bind and inhibit Rap1Gap2 (Drosophila melanogaster)
14-3-3zeta [cytosol] (Drosophila melanogaster)
RAP1GAP2:14-3-3beta, zeta [cytosol] (Drosophila melanogaster)
14-3-3zeta [cytosol] (Drosophila melanogaster)
Rap1 signal termination by Rap1GAPs (Drosophila melanogaster)
RAP1GAP2:14-3-3beta, zeta [cytosol] (Drosophila melanogaster)
14-3-3zeta [cytosol] (Drosophila melanogaster)
Metabolism of RNA (Drosophila melanogaster)
Regulation of mRNA stability by proteins that bind AU-rich elements (Drosophila melanogaster)
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA (Drosophila melanogaster)
p-S54,92,203-BRF1 binds 14-3-3 (Drosophila melanogaster)
14-3-3zeta [cytosol] (Drosophila melanogaster)
Phosphorylated BRF1 (Ser54, Ser92, Ser203):mRNA:14-3-3 Complex [cytosol] (Drosophila melanogaster)
14-3-3zeta [cytosol] (Drosophila melanogaster)
p-S92,203-BRF1 binds 14-3-3 (Drosophila melanogaster)
14-3-3zeta [cytosol] (Drosophila melanogaster)
Phosphorylated BRF1 (Ser92, Ser203):mRNA:14-3-3 Complex [cytosol] (Drosophila melanogaster)
14-3-3zeta [cytosol] (Drosophila melanogaster)
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA (Drosophila melanogaster)
p-S60,S186-ZFP36 (Tristetraproline, TTP) binds 14-3-3beta (Drosophila melanogaster)
14-3-3zeta [cytosol] (Drosophila melanogaster)
Phosphorylated TTP:mRNA:14-3-3 Complex [cytosol] (Drosophila melanogaster)
14-3-3zeta [cytosol] (Drosophila melanogaster)
Signal Transduction (Drosophila melanogaster)
MAPK family signaling cascades (Drosophila melanogaster)
MAPK1/MAPK3 signaling (Drosophila melanogaster)
RAF/MAP kinase cascade (Drosophila melanogaster)
MAP2K and MAPK activation (Drosophila melanogaster)
Dissociation of RAS:RAF complex (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
14-3-3zeta [cytosol] (Drosophila melanogaster)
p21RAS:GTP:activated RAF homo/heterodimers [plasma membrane] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
14-3-3zeta [cytosol] (Drosophila melanogaster)
Dual mechanism MAP2K inhibitors bind MAP2Ks (Drosophila melanogaster)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
14-3-3zeta [cytosol] (Drosophila melanogaster)
activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Drosophila melanogaster)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
14-3-3zeta [cytosol] (Drosophila melanogaster)
Dual mechanism MAPK inhibitors bind MAPKs (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
14-3-3zeta [cytosol] (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:MAPK:dual mechanism MAPK inhibitors [plasma membrane] (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
14-3-3zeta [cytosol] (Drosophila melanogaster)
MAP2Ks and MAPKs bind to the activated RAF complex (Drosophila melanogaster)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
14-3-3zeta [cytosol] (Drosophila melanogaster)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
14-3-3zeta [cytosol] (Drosophila melanogaster)
p21 RAS:GTP:activated RAF1 homo/heterodimer:PEBP1 [plasma membrane] (Drosophila melanogaster)
p21RAS:GTP:activated RAF1 homo/heterodimer [plasma membrane] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
14-3-3zeta [cytosol] (Drosophila melanogaster)
MAP2Ks phosphorylate MAPKs (Drosophila melanogaster)
activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Drosophila melanogaster)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
14-3-3zeta [cytosol] (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:MAPK:single mechanism MAP2K inhibitors [plasma membrane] (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
14-3-3zeta [cytosol] (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
14-3-3zeta [cytosol] (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:MAPK:dual mechanism MAPK inhibitors [plasma membrane] (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
14-3-3zeta [cytosol] (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
14-3-3zeta [cytosol] (Drosophila melanogaster)
RAF phosphorylates MAP2K dimer (Drosophila melanogaster)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
14-3-3zeta [cytosol] (Drosophila melanogaster)
activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Drosophila melanogaster)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
14-3-3zeta [cytosol] (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
14-3-3zeta [cytosol] (Drosophila melanogaster)
p21RAS:GTP:homo/heterodimerized RAF complex:RAF dimer inhibitors [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
'activator' RAF:YWHAB dimer [cytosol] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
14-3-3zeta [cytosol] (Drosophila melanogaster)
Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:MAPK:single mechanism MAP2K inhibitors [plasma membrane] (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
14-3-3zeta [cytosol] (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
14-3-3zeta [cytosol] (Drosophila melanogaster)
Single mechanism MAPK inhibitors bind phosphorylated MAPK (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
14-3-3zeta [cytosol] (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK:single mechanism MAPK inhibitors [plasma membrane] (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
14-3-3zeta [cytosol] (Drosophila melanogaster)
Negative regulation of MAPK pathway (Drosophila melanogaster)
PEBP1 binds activated RAF1 (Drosophila melanogaster)
p21 RAS:GTP:activated RAF1 homo/heterodimer:PEBP1 [plasma membrane] (Drosophila melanogaster)
p21RAS:GTP:activated RAF1 homo/heterodimer [plasma membrane] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
14-3-3zeta [cytosol] (Drosophila melanogaster)
p21RAS:GTP:activated RAF1 homo/heterodimer [plasma membrane] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
14-3-3zeta [cytosol] (Drosophila melanogaster)
PP2A dephosphorylates RAF1 (Drosophila melanogaster)
p21RAS:GTP:dephosphorylated RAF1 homo/heterodimer [plasma membrane] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
14-3-3zeta [cytosol] (Drosophila melanogaster)
p21RAS:GTP:p-S621 RAF1 homo/heterodimer [plasma membrane] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
14-3-3zeta [cytosol] (Drosophila melanogaster)
PP5 dephosphorylates RAF1 S338 (Drosophila melanogaster)
p21RAS:GTP:activated RAF1 homo/heterodimer [plasma membrane] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
14-3-3zeta [cytosol] (Drosophila melanogaster)
p21RAS:GTP:dephosphorylated RAF1 homo/heterodimer [plasma membrane] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
14-3-3zeta [cytosol] (Drosophila melanogaster)
RAF activation (Drosophila melanogaster)
"Activator" RAF:YWHAB dimer binds RAS:GTP (Drosophila melanogaster)
'activator' RAF:YWHAB dimer [cytosol] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
14-3-3zeta [cytosol] (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
'activator' RAF:YWHAB dimer [cytosol] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
14-3-3zeta [cytosol] (Drosophila melanogaster)
Inactive RAFs bind YWHAB (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
14-3-3zeta [cytosol] (Drosophila melanogaster)
inactive RAFs:YWHAB dimer [cytosol] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
14-3-3zeta [cytosol] (Drosophila melanogaster)
PP2A dephosphorylates KSR1 (Drosophila melanogaster)
p-S311 KSR1:MARK3:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
14-3-3zeta [cytosol] (Drosophila melanogaster)
p-S311,S406 KSR1:MARK3:YWHAB dimer [cytosol] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
14-3-3zeta [cytosol] (Drosophila melanogaster)
PP2A dephosphorylates inactive RAFs (Drosophila melanogaster)
dephosphorylated inactive RAFS:YWHAB dimer [cytosol] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
14-3-3zeta [cytosol] (Drosophila melanogaster)
inactive RAFs:YWHAB dimer [cytosol] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
14-3-3zeta [cytosol] (Drosophila melanogaster)
Phosphorylation of RAF (Drosophila melanogaster)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
14-3-3zeta [cytosol] (Drosophila melanogaster)
p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
'activator' RAF:YWHAB dimer [cytosol] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
14-3-3zeta [cytosol] (Drosophila melanogaster)
RAS:GTP:'activator' RAF homo/heterodimerizes with other RAF monomers (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
'activator' RAF:YWHAB dimer [cytosol] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
14-3-3zeta [cytosol] (Drosophila melanogaster)
p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
'activator' RAF:YWHAB dimer [cytosol] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
14-3-3zeta [cytosol] (Drosophila melanogaster)
Raf dimer inhibitors bind RAF heterodimers (Drosophila melanogaster)
p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
'activator' RAF:YWHAB dimer [cytosol] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
14-3-3zeta [cytosol] (Drosophila melanogaster)
p21RAS:GTP:homo/heterodimerized RAF complex:RAF dimer inhibitors [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
'activator' RAF:YWHAB dimer [cytosol] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
14-3-3zeta [cytosol] (Drosophila melanogaster)
YWHAB dimer dissociates from KSR1:MARK3 (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
14-3-3zeta [cytosol] (Drosophila melanogaster)
p-S311 KSR1:MARK3:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
14-3-3zeta [cytosol] (Drosophila melanogaster)
YWHAB dimer dissociates from dephosphorylated RAF (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
14-3-3zeta [cytosol] (Drosophila melanogaster)
dephosphorylated inactive RAFS:YWHAB dimer [cytosol] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
14-3-3zeta [cytosol] (Drosophila melanogaster)
p-S311,S406 KSR1:MARK3 binds YWHAB dimer (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
14-3-3zeta [cytosol] (Drosophila melanogaster)
p-S311,S406 KSR1:MARK3:YWHAB dimer [cytosol] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
14-3-3zeta [cytosol] (Drosophila melanogaster)
MTOR signalling (Drosophila melanogaster)
Phosphorylated AKT1S1:mTORC1 binds YWHAB (Drosophila melanogaster)
14-3-3zeta [cytosol] (Drosophila melanogaster)
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Drosophila melanogaster)
14-3-3zeta [cytosol] (Drosophila melanogaster)
mTORC1 phosphorylates AKT1S1 (Drosophila melanogaster)
mTORC1:RHEB:GTP:p-S183,T246-AKT1S1:YWHAB [lysosomal membrane] (Drosophila melanogaster)
14-3-3zeta [cytosol] (Drosophila melanogaster)
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Drosophila melanogaster)
14-3-3zeta [cytosol] (Drosophila melanogaster)
mTORC1-mediated signalling (Drosophila melanogaster)
Phosphorylation of 4E-BP1 by activated mTORC1 (Drosophila melanogaster)
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Drosophila melanogaster)
14-3-3zeta [cytosol] (Drosophila melanogaster)
mTORC1 phosphorylation of RPS6KB1 (S6K) (Drosophila melanogaster)
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Drosophila melanogaster)
14-3-3zeta [cytosol] (Drosophila melanogaster)
Signaling by Receptor Tyrosine Kinases (Drosophila melanogaster)
Signaling by NTRKs (Drosophila melanogaster)
Signaling by NTRK1 (TRKA) (Drosophila melanogaster)
Signalling to ERKs (Drosophila melanogaster)
Prolonged ERK activation events (Drosophila melanogaster)
Frs2-mediated activation (Drosophila melanogaster)
Activated BRAF phosphorylates MAP2K dimers downstream of RAP1 and NGF (Drosophila melanogaster)
BRAF dimer complex [cytosol] (Drosophila melanogaster)
B-Raf complex [cytosol] (Drosophila melanogaster)
14-3-3zeta [cytosol] (Drosophila melanogaster)
RAP1:GTP:activated BRAF dimer:MAPK2K:MAPK complex [endosome membrane] (Drosophila melanogaster)
RAP1:GTP:activated BRAF dimer [endosome membrane] (Drosophila melanogaster)
p-S445,T599,T602,S729 B-Raf complex [cytosol] (Drosophila melanogaster)
14-3-3zeta [cytosol] (Drosophila melanogaster)
RAP1:GTP:activated BRAF dimer:p-2S MAPK2K:MAPK complex [endosome membrane] (Drosophila melanogaster)
RAP1:GTP:activated BRAF dimer [endosome membrane] (Drosophila melanogaster)
p-S445,T599,T602,S729 B-Raf complex [cytosol] (Drosophila melanogaster)
14-3-3zeta [cytosol] (Drosophila melanogaster)
Activated BRAF recruits MAP2Ks and MAPKs to the endosome (Drosophila melanogaster)
RAP1:GTP:activated BRAF dimer [endosome membrane] (Drosophila melanogaster)
p-S445,T599,T602,S729 B-Raf complex [cytosol] (Drosophila melanogaster)
14-3-3zeta [cytosol] (Drosophila melanogaster)
RAP1:GTP:activated BRAF dimer:MAPK2K:MAPK complex [endosome membrane] (Drosophila melanogaster)
RAP1:GTP:activated BRAF dimer [endosome membrane] (Drosophila melanogaster)
p-S445,T599,T602,S729 B-Raf complex [cytosol] (Drosophila melanogaster)
14-3-3zeta [cytosol] (Drosophila melanogaster)
BRAF autophosphorylates downstream of RAP1 and NGF (Drosophila melanogaster)
BRAF dimer complex [cytosol] (Drosophila melanogaster)
B-Raf complex [cytosol] (Drosophila melanogaster)
14-3-3zeta [cytosol] (Drosophila melanogaster)
RAP1:GTP:B-Raf complex [endosome membrane] (Drosophila melanogaster)
BRAF dimer complex [cytosol] (Drosophila melanogaster)
B-Raf complex [cytosol] (Drosophila melanogaster)
14-3-3zeta [cytosol] (Drosophila melanogaster)
RAP1:GTP:activated BRAF dimer [endosome membrane] (Drosophila melanogaster)
p-S445,T599,T602,S729 B-Raf complex [cytosol] (Drosophila melanogaster)
14-3-3zeta [cytosol] (Drosophila melanogaster)
Dissociation of phosphorylated MAP2Ks and MAPKs (Drosophila melanogaster)
RAP1:GTP:activated BRAF dimer [endosome membrane] (Drosophila melanogaster)
p-S445,T599,T602,S729 B-Raf complex [cytosol] (Drosophila melanogaster)
14-3-3zeta [cytosol] (Drosophila melanogaster)
RAP1:GTP:activated BRAF dimer:p-2S MAPK2K:p-T,Y MAPK complex [endosome membrane] (Drosophila melanogaster)
RAP1:GTP:activated BRAF dimer [endosome membrane] (Drosophila melanogaster)
p-S445,T599,T602,S729 B-Raf complex [cytosol] (Drosophila melanogaster)
14-3-3zeta [cytosol] (Drosophila melanogaster)
MAP2Ks phosphorylate MAPKs downstream of BRAF and NGF (Drosophila melanogaster)
RAP1:GTP:activated BRAF dimer:p-2S MAPK2K:MAPK complex [endosome membrane] (Drosophila melanogaster)
RAP1:GTP:activated BRAF dimer [endosome membrane] (Drosophila melanogaster)
p-S445,T599,T602,S729 B-Raf complex [cytosol] (Drosophila melanogaster)
14-3-3zeta [cytosol] (Drosophila melanogaster)
RAP1:GTP:activated BRAF dimer:p-2S MAPK2K:p-T,Y MAPK complex [endosome membrane] (Drosophila melanogaster)
RAP1:GTP:activated BRAF dimer [endosome membrane] (Drosophila melanogaster)
p-S445,T599,T602,S729 B-Raf complex [cytosol] (Drosophila melanogaster)
14-3-3zeta [cytosol] (Drosophila melanogaster)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Drosophila melanogaster)
Signaling by Rho GTPases (Drosophila melanogaster)
RHO GTPase Effectors (Drosophila melanogaster)
RHO GTPases activate PKNs (Drosophila melanogaster)
Association of p-S216-CDC25C with 14-3-3 proteins (Drosophila melanogaster)
14-3-3 dimer [cytosol] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
14-3-3zeta [cytosol] (Drosophila melanogaster)
p-S216-CDC25C:14-3-3 protein complex [cytosol] (Drosophila melanogaster)
14-3-3 dimer [cytosol] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
14-3-3zeta [cytosol] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:P29310 14-3-3zeta
Gene Names
14-3-3zeta, 14-3-3, 14-3-3EZ, leo, THAP, CG17870
Chain
chain:1-248
Reference Genes
BioGPS Gene:36059 14-3-3zeta
CTD Gene:36059 14-3-3zeta
KEGG Gene (Drosophila melanogaster):Dmel_CG17870 14-3-3zeta
Monarch:36059 14-3-3zeta
NCBI Gene:36059 14-3-3zeta
Reference Transcript
RefSeq:NM_165740.3 14-3-3zeta
RefSeq:NM_001014515.2 14-3-3zeta
RefSeq:NM_001273916.1 14-3-3zeta
RefSeq:NM_165745.3 14-3-3zeta
RefSeq:NM_001014516.2 14-3-3zeta
RefSeq:NM_057537.4 14-3-3zeta
RefSeq:NM_001273917.1 14-3-3zeta
RefSeq:NM_165743.3 14-3-3zeta
RefSeq:NM_165741.3 14-3-3zeta
RefSeq:NM_165744.3 14-3-3zeta
RefSeq:NM_206070.2 14-3-3zeta
RefSeq:NM_165742.2 14-3-3zeta
Other Identifiers
153924_at
1625148_s_at
36059
GO:0000278
GO:0001223
GO:0005515
GO:0005634
GO:0005635
GO:0005737
GO:0005768
GO:0005769
GO:0005829
GO:0005886
GO:0006351
GO:0006355
GO:0006457
GO:0007010
GO:0007059
GO:0007163
GO:0007165
GO:0007294
GO:0007399
GO:0007460
GO:0007611
GO:0008103
GO:0008104
GO:0008134
GO:0016020
GO:0022414
GO:0023052
GO:0030154
GO:0031410
GO:0031965
GO:0035332
GO:0040040
GO:0042803
GO:0042994
GO:0043226
GO:0045172
GO:0045448
GO:0046579
GO:0046982
GO:0048856
GO:0050821
GO:0050877
GO:0051220
GO:0120176
GO:0140313
Participates
as an input of
p-S60,S186-ZFP36 (Tristetraproline, TTP) binds 14-3-3beta (Drosophila melanogaster)
p-S54,92,203-BRF1 binds 14-3-3 (Drosophila melanogaster)
p-S92,203-BRF1 binds 14-3-3 (Drosophila melanogaster)
14-3-3 proteins beta and zeta bind and inhibit Rap1Gap2 (Drosophila melanogaster)
Phosphorylated AKT1S1:mTORC1 binds YWHAB (Drosophila melanogaster)
as a component of
Phosphorylated TTP:mRNA:14-3-3 Complex [cytosol] (Drosophila melanogaster)
Phosphorylated BRF1 (Ser54, Ser92, Ser203):mRNA:14-3-3 Complex [cytosol] (Drosophila melanogaster)
Phosphorylated BRF1 (Ser92, Ser203):mRNA:14-3-3 Complex [cytosol] (Drosophila melanogaster)
RAP1GAP2:14-3-3beta, zeta [cytosol] (Drosophila melanogaster)
mTORC1:RHEB:GTP:p-S183,T246-AKT1S1:YWHAB [lysosomal membrane] (Drosophila melanogaster)
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Drosophila melanogaster)
B-Raf complex [cytosol] (Drosophila melanogaster)
p-S445,T599,T602,S729 B-Raf complex [cytosol] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
Other forms of this molecule
14-3-3zeta [cytosol]
14-3-3zeta [nucleoplasm]
14-3-3zeta [cytosol]
14-3-3zeta [cytosol]
14-3-3zeta [cytosol]
14-3-3zeta [cytosol]
Inferred From
14-3-3 beta, zeta [cytosol]
(Homo sapiens)
YWHAB [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_724885.1
,
NP_995792.1
,
NP_001014515.1
,
NP_001260846.1
,
NP_724888.2
,
NP_724889.2
,
NP_724887.2
,
NP_001014516.1
,
NP_001260845.1
,
NP_476885.2
,
NP_724886.1
,
NP_724884.1
Flybase
FBgn0004907
PRO
P29310
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q8IPH9 SLOB
0.66
5
UniProt:Q9VQ93 GOLP3
0.508
3
UniProt:Q9VS36 TO6BL
0.488
2
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