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Replication initiation regulation by E2F1/Rbf1
Stable Identifier
R-DME-113649
Type
Reaction [binding]
Species
Drosophila melanogaster
Compartment
nucleoplasm
ReviewStatus
5/5
General
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At the beginning of this reaction, 1 molecule of 'dRb1 protein', 1 molecule of 'RNA primer-DNA primer:origin duplex with DNA damage', and 1 molecule of 'dE2F1' are present. At the end of this reaction, 1 molecule of 'Aborted replication complex ' is present.
This reaction takes place in the 'nucleus'.
Literature References
PubMed ID
Title
Journal
Year
11231579
DNA replication control through interaction of E2F-RB and the origin recognition complex.
Bosco, G
,
Du, W
,
Orr-Weaver, TL
Nat Cell Biol
2001
Participants
Input
dE2F1 [nucleoplasm]
(Drosophila melanogaster)
dRb1 protein [nucleoplasm]
(Drosophila melanogaster)
RNA primer-DNA primer:origin duplex with DNA damage [nucleoplasm]
Output
Aborted replication complex [nucleoplasm]
(Drosophila melanogaster)
This event is regulated
Positively by
Regulator
dE2F1 [nucleoplasm]
(Drosophila melanogaster)
Orthologous Events
Replication initiation regulation by Rb1/E2F1 (Homo sapiens)
Created
Bosco, G (2004-06-16)
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