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PDPK1:PIP3 [plasma membrane]
Stable Identifier
R-DME-109697
Type
Complex
Species
Drosophila melanogaster
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Hemostasis (Drosophila melanogaster)
Platelet activation, signaling and aggregation (Drosophila melanogaster)
GPVI-mediated activation cascade (Drosophila melanogaster)
PIP3 recruits PDPK1 to the membrane (Drosophila melanogaster)
PDPK1:PIP3 [plasma membrane] (Drosophila melanogaster)
Immune System (Drosophila melanogaster)
Adaptive Immune System (Drosophila melanogaster)
Regulation of T cell activation by CD28 family (Drosophila melanogaster)
Co-stimulation by CD28 (Drosophila melanogaster)
CD28 dependent PI3K/Akt signaling (Drosophila melanogaster)
AKT binds PDPK1 (Drosophila melanogaster)
PDPK1:PIP3 [plasma membrane] (Drosophila melanogaster)
p-S-AKT:PDPK1:PIP3 [plasma membrane] (Drosophila melanogaster)
PDPK1:PIP3 [plasma membrane] (Drosophila melanogaster)
PIP3 recruits PDPK1 to the membrane (Drosophila melanogaster)
PDPK1:PIP3 [plasma membrane] (Drosophila melanogaster)
Signal Transduction (Drosophila melanogaster)
Intracellular signaling by second messengers (Drosophila melanogaster)
PIP3 activates AKT signaling (Drosophila melanogaster)
AKT binds PDPK1 (Drosophila melanogaster)
PDPK1:PIP3 [plasma membrane] (Drosophila melanogaster)
p-S-AKT:PDPK1:PIP3 [plasma membrane] (Drosophila melanogaster)
PDPK1:PIP3 [plasma membrane] (Drosophila melanogaster)
PIP3 recruits PDPK1 to the membrane (Drosophila melanogaster)
PDPK1:PIP3 [plasma membrane] (Drosophila melanogaster)
Signaling by Nuclear Receptors (Drosophila melanogaster)
ESR-mediated signaling (Drosophila melanogaster)
Extra-nuclear estrogen signaling (Drosophila melanogaster)
Estrogen-stimulated signaling through PRKCZ (Drosophila melanogaster)
ESR1- and PRCKZ-dependent MAPK1 translocation to the nucleus (Drosophila melanogaster)
PDPK1:PIP3:pS, p-T410 PRKCZ:p21 RAS:GTP [plasma membrane] (Drosophila melanogaster)
PDPK1:PIP3:pS, p-T410 PRKCZ [plasma membrane] (Drosophila melanogaster)
PDPK1:PIP3 [plasma membrane] (Drosophila melanogaster)
PRKCZ autophosphorylates downstream of estrogen stimulation (Drosophila melanogaster)
PDPK1:PIP3:p-T410-PRKCZ [plasma membrane] (Drosophila melanogaster)
PDPK1:PIP3 [plasma membrane] (Drosophila melanogaster)
PDPK1:PIP3:pS, p-T410 PRKCZ [plasma membrane] (Drosophila melanogaster)
PDPK1:PIP3 [plasma membrane] (Drosophila melanogaster)
PRKCZ recruits RAS in response to estrogen stimulation (Drosophila melanogaster)
PDPK1:PIP3:pS, p-T410 PRKCZ [plasma membrane] (Drosophila melanogaster)
PDPK1:PIP3 [plasma membrane] (Drosophila melanogaster)
PDPK1:PIP3:pS, p-T410 PRKCZ:p21 RAS:GDP [plasma membrane] (Drosophila melanogaster)
PDPK1:PIP3:pS, p-T410 PRKCZ [plasma membrane] (Drosophila melanogaster)
PDPK1:PIP3 [plasma membrane] (Drosophila melanogaster)
PRKCZ stimulates RAS nucleotide exchange in response to estrogen (Drosophila melanogaster)
PDPK1:PIP3:pS, p-T410 PRKCZ:p21 RAS:GDP [plasma membrane] (Drosophila melanogaster)
PDPK1:PIP3:pS, p-T410 PRKCZ [plasma membrane] (Drosophila melanogaster)
PDPK1:PIP3 [plasma membrane] (Drosophila melanogaster)
PDPK1:PIP3:pS, p-T410 PRKCZ:p21 RAS:GTP [plasma membrane] (Drosophila melanogaster)
PDPK1:PIP3:pS, p-T410 PRKCZ [plasma membrane] (Drosophila melanogaster)
PDPK1:PIP3 [plasma membrane] (Drosophila melanogaster)
Signaling by Receptor Tyrosine Kinases (Drosophila melanogaster)
Signaling by Insulin receptor (Drosophila melanogaster)
Insulin receptor signalling cascade (Drosophila melanogaster)
IRS-mediated signalling (Drosophila melanogaster)
PI3K Cascade (Drosophila melanogaster)
Activation of AKT2 (Drosophila melanogaster)
PDPK1 binds PIP3 (Drosophila melanogaster)
PDPK1:PIP3 [plasma membrane] (Drosophila melanogaster)
PDPK1 phosphorylates AKT2 (Drosophila melanogaster)
PDPK1:PIP3 [plasma membrane] (Drosophila melanogaster)
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) (Drosophila melanogaster)
IGF1R signaling cascade (Drosophila melanogaster)
IRS-related events triggered by IGF1R (Drosophila melanogaster)
IRS-mediated signalling (Drosophila melanogaster)
PI3K Cascade (Drosophila melanogaster)
Activation of AKT2 (Drosophila melanogaster)
PDPK1 binds PIP3 (Drosophila melanogaster)
PDPK1:PIP3 [plasma membrane] (Drosophila melanogaster)
PDPK1 phosphorylates AKT2 (Drosophila melanogaster)
PDPK1:PIP3 [plasma membrane] (Drosophila melanogaster)
Signaling by VEGF (Drosophila melanogaster)
VEGFA-VEGFR2 Pathway (Drosophila melanogaster)
VEGFR2 mediated vascular permeability (Drosophila melanogaster)
AKT binds PDPK1 (Drosophila melanogaster)
PDPK1:PIP3 [plasma membrane] (Drosophila melanogaster)
p-S-AKT:PDPK1:PIP3 [plasma membrane] (Drosophila melanogaster)
PDPK1:PIP3 [plasma membrane] (Drosophila melanogaster)
PIP3 recruits PDPK1 to the membrane (Drosophila melanogaster)
PDPK1:PIP3 [plasma membrane] (Drosophila melanogaster)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Drosophila melanogaster)
Signaling by Rho GTPases (Drosophila melanogaster)
RHO GTPase Effectors (Drosophila melanogaster)
RHO GTPases activate PKNs (Drosophila melanogaster)
PDPK1 phosphorylates PKN1,2,3 (Drosophila melanogaster)
PDPK1:PIP3 [plasma membrane] (Drosophila melanogaster)
RHOA,RHOB,RHOC,RAC1:GTP:PKN1-3:PDPK1:PIP3 [plasma membrane] (Drosophila melanogaster)
PDPK1:PIP3 [plasma membrane] (Drosophila melanogaster)
RHOA,RHOB,RHOC,RAC1:GTP:PKN1,2,3 binds PDPK1:PIP3 (Drosophila melanogaster)
PDPK1:PIP3 [plasma membrane] (Drosophila melanogaster)
RHOA,RHOB,RHOC,RAC1:GTP:PKN1-3:PDPK1:PIP3 [plasma membrane] (Drosophila melanogaster)
PDPK1:PIP3 [plasma membrane] (Drosophila melanogaster)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
PDPK1 [plasma membrane]
(Drosophila melanogaster)
PI(3,4,5)P3 [plasma membrane]
Participates
as a component of
PDPK1:PIP3:pS, p-T410 PRKCZ [plasma membrane] (Drosophila melanogaster)
PDPK1:PIP3:p-T410-PRKCZ [plasma membrane] (Drosophila melanogaster)
RHOA,RHOB,RHOC,RAC1:GTP:PKN1-3:PDPK1:PIP3 [plasma membrane] (Drosophila melanogaster)
p-S-AKT:PDPK1:PIP3 [plasma membrane] (Drosophila melanogaster)
as an output of
PDPK1 binds PIP3 (Drosophila melanogaster)
PDPK1 phosphorylates PKN1,2,3 (Drosophila melanogaster)
PIP3 recruits PDPK1 to the membrane (Drosophila melanogaster)
as an input of
RHOA,RHOB,RHOC,RAC1:GTP:PKN1,2,3 binds PDPK1:PIP3 (Drosophila melanogaster)
AKT binds PDPK1 (Drosophila melanogaster)
Inferred From
PDPK1:PIP3 [plasma membrane]
(Homo sapiens)
PDPK1:PIP3 [plasma membrane]
(Homo sapiens)
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