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eif4g [cytosol]
Stable Identifier
R-DDI-72584
Type
Protein [EntityWithAccessionedSequence]
Species
Dictyostelium discoideum
Compartment
cytosol
Synonyms
EIF4G1, Q553R3
Locations in the PathwayBrowser
Expand all
Metabolism of RNA (Dictyostelium discoideum)
Nonsense-Mediated Decay (NMD) (Dictyostelium discoideum)
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) (Dictyostelium discoideum)
SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Dictyostelium discoideum)
SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Dictyostelium discoideum)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Dictyostelium discoideum)
mRNA Complex with a Premature Termination Codon Preceding an Exon Junction [cytosol] (Dictyostelium discoideum)
eif4g [cytosol] (Dictyostelium discoideum)
SMG1:UPF1:EJC:Translated mRNP [cytosol] (Dictyostelium discoideum)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Dictyostelium discoideum)
mRNA Complex with a Premature Termination Codon Preceding an Exon Junction [cytosol] (Dictyostelium discoideum)
eif4g [cytosol] (Dictyostelium discoideum)
UPF1 binds an mRNP with a termination codon preceding an Exon Junction Complex (Dictyostelium discoideum)
SMG1:UPF1:EJC:Translated mRNP [cytosol] (Dictyostelium discoideum)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Dictyostelium discoideum)
mRNA Complex with a Premature Termination Codon Preceding an Exon Junction [cytosol] (Dictyostelium discoideum)
eif4g [cytosol] (Dictyostelium discoideum)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Dictyostelium discoideum)
mRNA Complex with a Premature Termination Codon Preceding an Exon Junction [cytosol] (Dictyostelium discoideum)
eif4g [cytosol] (Dictyostelium discoideum)
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) (Dictyostelium discoideum)
Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex (Dictyostelium discoideum)
Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Dictyostelium discoideum)
mRNA Complex with a Premature Termination Codon Not Preceding an Exon Junction [cytosol] (Dictyostelium discoideum)
eif4g [cytosol] (Dictyostelium discoideum)
UPF1:eRF3 Complex on Translated mRNA [cytosol] (Dictyostelium discoideum)
Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Dictyostelium discoideum)
mRNA Complex with a Premature Termination Codon Not Preceding an Exon Junction [cytosol] (Dictyostelium discoideum)
eif4g [cytosol] (Dictyostelium discoideum)
Regulation of mRNA stability by proteins that bind AU-rich elements (Dictyostelium discoideum)
AUF1 (hnRNP D0) binds and destabilizes mRNA (Dictyostelium discoideum)
AUF1 (hnRNP D0) is ubiquitinylated (Dictyostelium discoideum)
AUF1 Complexed with Translation and Heat Shock Proteins [cytosol] (Dictyostelium discoideum)
eif4g [cytosol] (Dictyostelium discoideum)
Metabolism of proteins (Dictyostelium discoideum)
Translation (Dictyostelium discoideum)
Eukaryotic Translation Initiation (Dictyostelium discoideum)
Cap-dependent Translation Initiation (Dictyostelium discoideum)
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S (Dictyostelium discoideum)
Formation of the cap-binding eIF4F complex (Dictyostelium discoideum)
eIF4F [cytosol] (Dictyostelium discoideum)
eif4g [cytosol] (Dictyostelium discoideum)
eif4g [cytosol] (Dictyostelium discoideum)
Ribosomal scanning and start codon recognition (Dictyostelium discoideum)
Ribosomal scanning (Dictyostelium discoideum)
48S complex [cytosol] (Dictyostelium discoideum)
eIF4F [cytosol] (Dictyostelium discoideum)
eif4g [cytosol] (Dictyostelium discoideum)
Start codon recognition (Dictyostelium discoideum)
48S complex [cytosol] (Dictyostelium discoideum)
eIF4F [cytosol] (Dictyostelium discoideum)
eif4g [cytosol] (Dictyostelium discoideum)
L13a-mediated translational silencing of Ceruloplasmin expression (Dictyostelium discoideum)
Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA (Dictyostelium discoideum)
43S: Ceruloplasmin mRNA:eIF4F:eIF4B:eIF4H:PABP [cytosol] (Dictyostelium discoideum)
eIF4F [cytosol] (Dictyostelium discoideum)
eif4g [cytosol] (Dictyostelium discoideum)
phospho-L13a associated wth the 3' UTR GAIT element of ceruloplasmin mRNA within the translation initiation complex [cytosol] (Dictyostelium discoideum)
43S: Ceruloplasmin mRNA:eIF4F:eIF4B:eIF4H:PABP [cytosol] (Dictyostelium discoideum)
eIF4F [cytosol] (Dictyostelium discoideum)
eif4g [cytosol] (Dictyostelium discoideum)
Signal Transduction (Dictyostelium discoideum)
MTOR signalling (Dictyostelium discoideum)
mTORC1-mediated signalling (Dictyostelium discoideum)
Phosphorylation and activation of eIF4G by activated S6K1 (Dictyostelium discoideum)
eif4g [cytosol] (Dictyostelium discoideum)
External Reference Information
External Reference
UniProt:Q553R3
Gene Names
eif4g
Reference Genes
BioGPS Gene:8619923 eif4g
dictyBase:DDB_G0275395
ENSEMBL:DDB_G0275395
KEGG Gene (Dictyostelium discoideum):DDB_G0275395 eif4g
Monarch:8619923 eif4g
NCBI Gene:8619923 eif4g
Reference Transcript
RefSeq:XM_638565.1 eif4g
Participates
as a component of
AUF1 Complexed with Translation and Heat Shock Proteins [cytosol] (Dictyostelium discoideum)
mRNA Complex with a Premature Termination Codon Preceding an Exon Junction [cytosol] (Dictyostelium discoideum)
mRNA Complex with a Premature Termination Codon Not Preceding an Exon Junction [cytosol] (Dictyostelium discoideum)
eIF4F [cytosol] (Dictyostelium discoideum)
as an input of
Formation of the cap-binding eIF4F complex (Dictyostelium discoideum)
Phosphorylation and activation of eIF4G by activated S6K1 (Dictyostelium discoideum)
Other forms of this molecule
eif4g [cytosol]
eif4g [cytosol]
phospho-eif4g [cytosol]
Inferred From
EIF4G1 [cytosol]
(Homo sapiens)
Cross References
RefSeq
XP_643657.1
PRO
Q553R3
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