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About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
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Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
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Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
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Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
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POLA1 [nucleoplasm]
Stable Identifier
R-DDI-68487
Type
Protein [EntityWithAccessionedSequence]
Species
Dictyostelium discoideum
Compartment
nucleoplasm
Synonyms
Q54SV8
Locations in the PathwayBrowser
Expand all
Cell Cycle (Dictyostelium discoideum)
Cell Cycle, Mitotic (Dictyostelium discoideum)
Mitotic G1 phase and G1/S transition (Dictyostelium discoideum)
G1/S Transition (Dictyostelium discoideum)
Activation of the pre-replicative complex (Dictyostelium discoideum)
DNA polymerase alpha:primase binds at the origin (Dictyostelium discoideum)
DNA polymerase alpha:primase [nucleoplasm] (Dictyostelium discoideum)
POLA1 [nucleoplasm] (Dictyostelium discoideum)
DNA polymerase alpha:primase:DNA polymerase alpha:origin complex [nucleoplasm] (Dictyostelium discoideum)
DNA polymerase alpha:primase [nucleoplasm] (Dictyostelium discoideum)
POLA1 [nucleoplasm] (Dictyostelium discoideum)
E2F mediated regulation of DNA replication (Dictyostelium discoideum)
Inhibition of replication initiation of damaged DNA by RB1/E2F1 (Dictyostelium discoideum)
Detection of damage during initiation of DNA synthesis in S-phase (Dictyostelium discoideum)
DNA polymerase alpha:primase [nucleoplasm] (Dictyostelium discoideum)
POLA1 [nucleoplasm] (Dictyostelium discoideum)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Dictyostelium discoideum)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Dictyostelium discoideum)
DNA polymerase alpha:primase [nucleoplasm] (Dictyostelium discoideum)
POLA1 [nucleoplasm] (Dictyostelium discoideum)
S Phase (Dictyostelium discoideum)
Synthesis of DNA (Dictyostelium discoideum)
DNA replication initiation (Dictyostelium discoideum)
The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin (Dictyostelium discoideum)
DNA polymerase alpha:primase [nucleoplasm] (Dictyostelium discoideum)
POLA1 [nucleoplasm] (Dictyostelium discoideum)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Dictyostelium discoideum)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Dictyostelium discoideum)
DNA polymerase alpha:primase [nucleoplasm] (Dictyostelium discoideum)
POLA1 [nucleoplasm] (Dictyostelium discoideum)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Dictyostelium discoideum)
DNA polymerase alpha:primase [nucleoplasm] (Dictyostelium discoideum)
POLA1 [nucleoplasm] (Dictyostelium discoideum)
The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer at the origin (Dictyostelium discoideum)
DNA polymerase alpha:primase [nucleoplasm] (Dictyostelium discoideum)
POLA1 [nucleoplasm] (Dictyostelium discoideum)
DNA polymerase alpha:primase:DNA polymerase alpha:origin complex [nucleoplasm] (Dictyostelium discoideum)
DNA polymerase alpha:primase [nucleoplasm] (Dictyostelium discoideum)
POLA1 [nucleoplasm] (Dictyostelium discoideum)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Dictyostelium discoideum)
DNA polymerase alpha:primase [nucleoplasm] (Dictyostelium discoideum)
POLA1 [nucleoplasm] (Dictyostelium discoideum)
DNA strand elongation (Dictyostelium discoideum)
Lagging Strand Synthesis (Dictyostelium discoideum)
Polymerase switching (Dictyostelium discoideum)
Formation of Processive Complex (Dictyostelium discoideum)
Processive complex [nucleoplasm] (Dictyostelium discoideum)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Dictyostelium discoideum)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Dictyostelium discoideum)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Dictyostelium discoideum)
DNA polymerase alpha:primase [nucleoplasm] (Dictyostelium discoideum)
POLA1 [nucleoplasm] (Dictyostelium discoideum)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Dictyostelium discoideum)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Dictyostelium discoideum)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Dictyostelium discoideum)
DNA polymerase alpha:primase [nucleoplasm] (Dictyostelium discoideum)
POLA1 [nucleoplasm] (Dictyostelium discoideum)
Loading of PCNA - Sliding Clamp Formation (Dictyostelium discoideum)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Dictyostelium discoideum)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Dictyostelium discoideum)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Dictyostelium discoideum)
DNA polymerase alpha:primase [nucleoplasm] (Dictyostelium discoideum)
POLA1 [nucleoplasm] (Dictyostelium discoideum)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex:PCNA homotrimer [nucleoplasm] (Dictyostelium discoideum)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Dictyostelium discoideum)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Dictyostelium discoideum)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Dictyostelium discoideum)
DNA polymerase alpha:primase [nucleoplasm] (Dictyostelium discoideum)
POLA1 [nucleoplasm] (Dictyostelium discoideum)
RFC binding displaces Pol Alpha (Dictyostelium discoideum)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Dictyostelium discoideum)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Dictyostelium discoideum)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Dictyostelium discoideum)
DNA polymerase alpha:primase [nucleoplasm] (Dictyostelium discoideum)
POLA1 [nucleoplasm] (Dictyostelium discoideum)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Dictyostelium discoideum)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Dictyostelium discoideum)
DNA polymerase alpha:primase [nucleoplasm] (Dictyostelium discoideum)
POLA1 [nucleoplasm] (Dictyostelium discoideum)
RFC dissociates after sliding clamp formation (Dictyostelium discoideum)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex:PCNA homotrimer [nucleoplasm] (Dictyostelium discoideum)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Dictyostelium discoideum)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Dictyostelium discoideum)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Dictyostelium discoideum)
DNA polymerase alpha:primase [nucleoplasm] (Dictyostelium discoideum)
POLA1 [nucleoplasm] (Dictyostelium discoideum)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Dictyostelium discoideum)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Dictyostelium discoideum)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Dictyostelium discoideum)
DNA polymerase alpha:primase [nucleoplasm] (Dictyostelium discoideum)
POLA1 [nucleoplasm] (Dictyostelium discoideum)
Processive synthesis on the lagging strand (Dictyostelium discoideum)
Formation of Okazaki fragments (Dictyostelium discoideum)
Processive complex [nucleoplasm] (Dictyostelium discoideum)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Dictyostelium discoideum)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Dictyostelium discoideum)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Dictyostelium discoideum)
DNA polymerase alpha:primase [nucleoplasm] (Dictyostelium discoideum)
POLA1 [nucleoplasm] (Dictyostelium discoideum)
Processive complex:Okazaki fragment complex [nucleoplasm] (Dictyostelium discoideum)
Processive complex [nucleoplasm] (Dictyostelium discoideum)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Dictyostelium discoideum)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Dictyostelium discoideum)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Dictyostelium discoideum)
DNA polymerase alpha:primase [nucleoplasm] (Dictyostelium discoideum)
POLA1 [nucleoplasm] (Dictyostelium discoideum)
Formation of the Flap Intermediate (Dictyostelium discoideum)
Processive complex:Okazaki fragment complex [nucleoplasm] (Dictyostelium discoideum)
Processive complex [nucleoplasm] (Dictyostelium discoideum)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Dictyostelium discoideum)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Dictyostelium discoideum)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Dictyostelium discoideum)
DNA polymerase alpha:primase [nucleoplasm] (Dictyostelium discoideum)
POLA1 [nucleoplasm] (Dictyostelium discoideum)
Processive complex:Okazaki fragment:Flap [nucleoplasm] (Dictyostelium discoideum)
Processive complex:Okazaki fragment complex [nucleoplasm] (Dictyostelium discoideum)
Processive complex [nucleoplasm] (Dictyostelium discoideum)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Dictyostelium discoideum)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Dictyostelium discoideum)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Dictyostelium discoideum)
DNA polymerase alpha:primase [nucleoplasm] (Dictyostelium discoideum)
POLA1 [nucleoplasm] (Dictyostelium discoideum)
Removal of the Flap Intermediate (Dictyostelium discoideum)
Removal of remaining Flap (Dictyostelium discoideum)
Processive complex:Okazaki fragments:Remaining Flap [nucleoplasm] (Dictyostelium discoideum)
Processive complex [nucleoplasm] (Dictyostelium discoideum)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Dictyostelium discoideum)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Dictyostelium discoideum)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Dictyostelium discoideum)
DNA polymerase alpha:primase [nucleoplasm] (Dictyostelium discoideum)
POLA1 [nucleoplasm] (Dictyostelium discoideum)
Processive complex:nicked DNA from adjacent Okazaki fragments [nucleoplasm] (Dictyostelium discoideum)
Processive complex [nucleoplasm] (Dictyostelium discoideum)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Dictyostelium discoideum)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Dictyostelium discoideum)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Dictyostelium discoideum)
DNA polymerase alpha:primase [nucleoplasm] (Dictyostelium discoideum)
POLA1 [nucleoplasm] (Dictyostelium discoideum)
Leading Strand Synthesis (Dictyostelium discoideum)
Polymerase switching (Dictyostelium discoideum)
Formation of Processive Complex (Dictyostelium discoideum)
Processive complex [nucleoplasm] (Dictyostelium discoideum)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Dictyostelium discoideum)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Dictyostelium discoideum)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Dictyostelium discoideum)
DNA polymerase alpha:primase [nucleoplasm] (Dictyostelium discoideum)
POLA1 [nucleoplasm] (Dictyostelium discoideum)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Dictyostelium discoideum)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Dictyostelium discoideum)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Dictyostelium discoideum)
DNA polymerase alpha:primase [nucleoplasm] (Dictyostelium discoideum)
POLA1 [nucleoplasm] (Dictyostelium discoideum)
Loading of PCNA - Sliding Clamp Formation (Dictyostelium discoideum)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Dictyostelium discoideum)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Dictyostelium discoideum)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Dictyostelium discoideum)
DNA polymerase alpha:primase [nucleoplasm] (Dictyostelium discoideum)
POLA1 [nucleoplasm] (Dictyostelium discoideum)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex:PCNA homotrimer [nucleoplasm] (Dictyostelium discoideum)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Dictyostelium discoideum)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Dictyostelium discoideum)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Dictyostelium discoideum)
DNA polymerase alpha:primase [nucleoplasm] (Dictyostelium discoideum)
POLA1 [nucleoplasm] (Dictyostelium discoideum)
RFC binding displaces Pol Alpha (Dictyostelium discoideum)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Dictyostelium discoideum)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Dictyostelium discoideum)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Dictyostelium discoideum)
DNA polymerase alpha:primase [nucleoplasm] (Dictyostelium discoideum)
POLA1 [nucleoplasm] (Dictyostelium discoideum)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Dictyostelium discoideum)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Dictyostelium discoideum)
DNA polymerase alpha:primase [nucleoplasm] (Dictyostelium discoideum)
POLA1 [nucleoplasm] (Dictyostelium discoideum)
RFC dissociates after sliding clamp formation (Dictyostelium discoideum)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex:PCNA homotrimer [nucleoplasm] (Dictyostelium discoideum)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Dictyostelium discoideum)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Dictyostelium discoideum)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Dictyostelium discoideum)
DNA polymerase alpha:primase [nucleoplasm] (Dictyostelium discoideum)
POLA1 [nucleoplasm] (Dictyostelium discoideum)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Dictyostelium discoideum)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Dictyostelium discoideum)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Dictyostelium discoideum)
DNA polymerase alpha:primase [nucleoplasm] (Dictyostelium discoideum)
POLA1 [nucleoplasm] (Dictyostelium discoideum)
DNA Replication (Dictyostelium discoideum)
DNA Replication Pre-Initiation (Dictyostelium discoideum)
Activation of the pre-replicative complex (Dictyostelium discoideum)
DNA polymerase alpha:primase binds at the origin (Dictyostelium discoideum)
DNA polymerase alpha:primase [nucleoplasm] (Dictyostelium discoideum)
POLA1 [nucleoplasm] (Dictyostelium discoideum)
DNA polymerase alpha:primase:DNA polymerase alpha:origin complex [nucleoplasm] (Dictyostelium discoideum)
DNA polymerase alpha:primase [nucleoplasm] (Dictyostelium discoideum)
POLA1 [nucleoplasm] (Dictyostelium discoideum)
Synthesis of DNA (Dictyostelium discoideum)
DNA replication initiation (Dictyostelium discoideum)
The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin (Dictyostelium discoideum)
DNA polymerase alpha:primase [nucleoplasm] (Dictyostelium discoideum)
POLA1 [nucleoplasm] (Dictyostelium discoideum)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Dictyostelium discoideum)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Dictyostelium discoideum)
DNA polymerase alpha:primase [nucleoplasm] (Dictyostelium discoideum)
POLA1 [nucleoplasm] (Dictyostelium discoideum)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Dictyostelium discoideum)
DNA polymerase alpha:primase [nucleoplasm] (Dictyostelium discoideum)
POLA1 [nucleoplasm] (Dictyostelium discoideum)
The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer at the origin (Dictyostelium discoideum)
DNA polymerase alpha:primase [nucleoplasm] (Dictyostelium discoideum)
POLA1 [nucleoplasm] (Dictyostelium discoideum)
DNA polymerase alpha:primase:DNA polymerase alpha:origin complex [nucleoplasm] (Dictyostelium discoideum)
DNA polymerase alpha:primase [nucleoplasm] (Dictyostelium discoideum)
POLA1 [nucleoplasm] (Dictyostelium discoideum)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Dictyostelium discoideum)
DNA polymerase alpha:primase [nucleoplasm] (Dictyostelium discoideum)
POLA1 [nucleoplasm] (Dictyostelium discoideum)
DNA strand elongation (Dictyostelium discoideum)
Lagging Strand Synthesis (Dictyostelium discoideum)
Polymerase switching (Dictyostelium discoideum)
Formation of Processive Complex (Dictyostelium discoideum)
Processive complex [nucleoplasm] (Dictyostelium discoideum)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Dictyostelium discoideum)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Dictyostelium discoideum)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Dictyostelium discoideum)
DNA polymerase alpha:primase [nucleoplasm] (Dictyostelium discoideum)
POLA1 [nucleoplasm] (Dictyostelium discoideum)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Dictyostelium discoideum)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Dictyostelium discoideum)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Dictyostelium discoideum)
DNA polymerase alpha:primase [nucleoplasm] (Dictyostelium discoideum)
POLA1 [nucleoplasm] (Dictyostelium discoideum)
Loading of PCNA - Sliding Clamp Formation (Dictyostelium discoideum)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Dictyostelium discoideum)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Dictyostelium discoideum)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Dictyostelium discoideum)
DNA polymerase alpha:primase [nucleoplasm] (Dictyostelium discoideum)
POLA1 [nucleoplasm] (Dictyostelium discoideum)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex:PCNA homotrimer [nucleoplasm] (Dictyostelium discoideum)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Dictyostelium discoideum)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Dictyostelium discoideum)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Dictyostelium discoideum)
DNA polymerase alpha:primase [nucleoplasm] (Dictyostelium discoideum)
POLA1 [nucleoplasm] (Dictyostelium discoideum)
RFC binding displaces Pol Alpha (Dictyostelium discoideum)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Dictyostelium discoideum)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Dictyostelium discoideum)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Dictyostelium discoideum)
DNA polymerase alpha:primase [nucleoplasm] (Dictyostelium discoideum)
POLA1 [nucleoplasm] (Dictyostelium discoideum)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Dictyostelium discoideum)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Dictyostelium discoideum)
DNA polymerase alpha:primase [nucleoplasm] (Dictyostelium discoideum)
POLA1 [nucleoplasm] (Dictyostelium discoideum)
RFC dissociates after sliding clamp formation (Dictyostelium discoideum)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex:PCNA homotrimer [nucleoplasm] (Dictyostelium discoideum)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Dictyostelium discoideum)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Dictyostelium discoideum)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Dictyostelium discoideum)
DNA polymerase alpha:primase [nucleoplasm] (Dictyostelium discoideum)
POLA1 [nucleoplasm] (Dictyostelium discoideum)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Dictyostelium discoideum)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Dictyostelium discoideum)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Dictyostelium discoideum)
DNA polymerase alpha:primase [nucleoplasm] (Dictyostelium discoideum)
POLA1 [nucleoplasm] (Dictyostelium discoideum)
Processive synthesis on the lagging strand (Dictyostelium discoideum)
Formation of Okazaki fragments (Dictyostelium discoideum)
Processive complex [nucleoplasm] (Dictyostelium discoideum)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Dictyostelium discoideum)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Dictyostelium discoideum)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Dictyostelium discoideum)
DNA polymerase alpha:primase [nucleoplasm] (Dictyostelium discoideum)
POLA1 [nucleoplasm] (Dictyostelium discoideum)
Processive complex:Okazaki fragment complex [nucleoplasm] (Dictyostelium discoideum)
Processive complex [nucleoplasm] (Dictyostelium discoideum)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Dictyostelium discoideum)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Dictyostelium discoideum)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Dictyostelium discoideum)
DNA polymerase alpha:primase [nucleoplasm] (Dictyostelium discoideum)
POLA1 [nucleoplasm] (Dictyostelium discoideum)
Formation of the Flap Intermediate (Dictyostelium discoideum)
Processive complex:Okazaki fragment complex [nucleoplasm] (Dictyostelium discoideum)
Processive complex [nucleoplasm] (Dictyostelium discoideum)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Dictyostelium discoideum)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Dictyostelium discoideum)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Dictyostelium discoideum)
DNA polymerase alpha:primase [nucleoplasm] (Dictyostelium discoideum)
POLA1 [nucleoplasm] (Dictyostelium discoideum)
Processive complex:Okazaki fragment:Flap [nucleoplasm] (Dictyostelium discoideum)
Processive complex:Okazaki fragment complex [nucleoplasm] (Dictyostelium discoideum)
Processive complex [nucleoplasm] (Dictyostelium discoideum)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Dictyostelium discoideum)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Dictyostelium discoideum)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Dictyostelium discoideum)
DNA polymerase alpha:primase [nucleoplasm] (Dictyostelium discoideum)
POLA1 [nucleoplasm] (Dictyostelium discoideum)
Removal of the Flap Intermediate (Dictyostelium discoideum)
Removal of remaining Flap (Dictyostelium discoideum)
Processive complex:Okazaki fragments:Remaining Flap [nucleoplasm] (Dictyostelium discoideum)
Processive complex [nucleoplasm] (Dictyostelium discoideum)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Dictyostelium discoideum)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Dictyostelium discoideum)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Dictyostelium discoideum)
DNA polymerase alpha:primase [nucleoplasm] (Dictyostelium discoideum)
POLA1 [nucleoplasm] (Dictyostelium discoideum)
Processive complex:nicked DNA from adjacent Okazaki fragments [nucleoplasm] (Dictyostelium discoideum)
Processive complex [nucleoplasm] (Dictyostelium discoideum)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Dictyostelium discoideum)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Dictyostelium discoideum)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Dictyostelium discoideum)
DNA polymerase alpha:primase [nucleoplasm] (Dictyostelium discoideum)
POLA1 [nucleoplasm] (Dictyostelium discoideum)
Leading Strand Synthesis (Dictyostelium discoideum)
Polymerase switching (Dictyostelium discoideum)
Formation of Processive Complex (Dictyostelium discoideum)
Processive complex [nucleoplasm] (Dictyostelium discoideum)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Dictyostelium discoideum)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Dictyostelium discoideum)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Dictyostelium discoideum)
DNA polymerase alpha:primase [nucleoplasm] (Dictyostelium discoideum)
POLA1 [nucleoplasm] (Dictyostelium discoideum)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Dictyostelium discoideum)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Dictyostelium discoideum)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Dictyostelium discoideum)
DNA polymerase alpha:primase [nucleoplasm] (Dictyostelium discoideum)
POLA1 [nucleoplasm] (Dictyostelium discoideum)
Loading of PCNA - Sliding Clamp Formation (Dictyostelium discoideum)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Dictyostelium discoideum)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Dictyostelium discoideum)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Dictyostelium discoideum)
DNA polymerase alpha:primase [nucleoplasm] (Dictyostelium discoideum)
POLA1 [nucleoplasm] (Dictyostelium discoideum)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex:PCNA homotrimer [nucleoplasm] (Dictyostelium discoideum)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Dictyostelium discoideum)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Dictyostelium discoideum)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Dictyostelium discoideum)
DNA polymerase alpha:primase [nucleoplasm] (Dictyostelium discoideum)
POLA1 [nucleoplasm] (Dictyostelium discoideum)
RFC binding displaces Pol Alpha (Dictyostelium discoideum)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Dictyostelium discoideum)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Dictyostelium discoideum)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Dictyostelium discoideum)
DNA polymerase alpha:primase [nucleoplasm] (Dictyostelium discoideum)
POLA1 [nucleoplasm] (Dictyostelium discoideum)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Dictyostelium discoideum)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Dictyostelium discoideum)
DNA polymerase alpha:primase [nucleoplasm] (Dictyostelium discoideum)
POLA1 [nucleoplasm] (Dictyostelium discoideum)
RFC dissociates after sliding clamp formation (Dictyostelium discoideum)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex:PCNA homotrimer [nucleoplasm] (Dictyostelium discoideum)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Dictyostelium discoideum)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Dictyostelium discoideum)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Dictyostelium discoideum)
DNA polymerase alpha:primase [nucleoplasm] (Dictyostelium discoideum)
POLA1 [nucleoplasm] (Dictyostelium discoideum)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Dictyostelium discoideum)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Dictyostelium discoideum)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Dictyostelium discoideum)
DNA polymerase alpha:primase [nucleoplasm] (Dictyostelium discoideum)
POLA1 [nucleoplasm] (Dictyostelium discoideum)
External Reference Information
External Reference
UniProt:Q54SV8
Reference Genes
BioGPS Gene:8623451
dictyBase:DDB_G0282191
ENSEMBL:DDB_G0282191
KEGG:ddi:DDB_G0282191
Monarch:8623451
NCBI Gene:8623451
UCSC:Q54SV8
Reference Transcript
RefSeq:XM_635185.1
Participates
as a component of
DNA polymerase alpha:primase [nucleoplasm] (Dictyostelium discoideum)
Inferred From
POLA1 [nucleoplasm]
(Homo sapiens)
Cross References
RefSeq
XP_640277.1
PRO
Q54SV8
© 2026
Reactome
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