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RFC2 [nucleoplasm]
Stable Identifier
R-DDI-68433
Type
Protein [EntityWithAccessionedSequence]
Species
Dictyostelium discoideum
Compartment
nucleoplasm
Synonyms
Q54E21
Locations in the PathwayBrowser
Expand all
Cell Cycle (Dictyostelium discoideum)
Cell Cycle, Mitotic (Dictyostelium discoideum)
S Phase (Dictyostelium discoideum)
Synthesis of DNA (Dictyostelium discoideum)
DNA strand elongation (Dictyostelium discoideum)
Lagging Strand Synthesis (Dictyostelium discoideum)
Polymerase switching (Dictyostelium discoideum)
Loading of PCNA - Sliding Clamp Formation (Dictyostelium discoideum)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Dictyostelium discoideum)
RFC Heteropentamer [nucleoplasm] (Dictyostelium discoideum)
RFC2 [nucleoplasm] (Dictyostelium discoideum)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex:PCNA homotrimer [nucleoplasm] (Dictyostelium discoideum)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Dictyostelium discoideum)
RFC Heteropentamer [nucleoplasm] (Dictyostelium discoideum)
RFC2 [nucleoplasm] (Dictyostelium discoideum)
RFC binding displaces Pol Alpha (Dictyostelium discoideum)
RFC Heteropentamer [nucleoplasm] (Dictyostelium discoideum)
RFC2 [nucleoplasm] (Dictyostelium discoideum)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Dictyostelium discoideum)
RFC Heteropentamer [nucleoplasm] (Dictyostelium discoideum)
RFC2 [nucleoplasm] (Dictyostelium discoideum)
RFC dissociates after sliding clamp formation (Dictyostelium discoideum)
RFC Heteropentamer [nucleoplasm] (Dictyostelium discoideum)
RFC2 [nucleoplasm] (Dictyostelium discoideum)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex:PCNA homotrimer [nucleoplasm] (Dictyostelium discoideum)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Dictyostelium discoideum)
RFC Heteropentamer [nucleoplasm] (Dictyostelium discoideum)
RFC2 [nucleoplasm] (Dictyostelium discoideum)
Leading Strand Synthesis (Dictyostelium discoideum)
Polymerase switching (Dictyostelium discoideum)
Loading of PCNA - Sliding Clamp Formation (Dictyostelium discoideum)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Dictyostelium discoideum)
RFC Heteropentamer [nucleoplasm] (Dictyostelium discoideum)
RFC2 [nucleoplasm] (Dictyostelium discoideum)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex:PCNA homotrimer [nucleoplasm] (Dictyostelium discoideum)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Dictyostelium discoideum)
RFC Heteropentamer [nucleoplasm] (Dictyostelium discoideum)
RFC2 [nucleoplasm] (Dictyostelium discoideum)
RFC binding displaces Pol Alpha (Dictyostelium discoideum)
RFC Heteropentamer [nucleoplasm] (Dictyostelium discoideum)
RFC2 [nucleoplasm] (Dictyostelium discoideum)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Dictyostelium discoideum)
RFC Heteropentamer [nucleoplasm] (Dictyostelium discoideum)
RFC2 [nucleoplasm] (Dictyostelium discoideum)
RFC dissociates after sliding clamp formation (Dictyostelium discoideum)
RFC Heteropentamer [nucleoplasm] (Dictyostelium discoideum)
RFC2 [nucleoplasm] (Dictyostelium discoideum)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex:PCNA homotrimer [nucleoplasm] (Dictyostelium discoideum)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Dictyostelium discoideum)
RFC Heteropentamer [nucleoplasm] (Dictyostelium discoideum)
RFC2 [nucleoplasm] (Dictyostelium discoideum)
DNA Repair (Dictyostelium discoideum)
DNA Double-Strand Break Repair (Dictyostelium discoideum)
Homology Directed Repair (Dictyostelium discoideum)
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) (Dictyostelium discoideum)
HDR through Single Strand Annealing (SSA) (Dictyostelium discoideum)
ERCC1:XPF cleaves flaps generated by SSA (Dictyostelium discoideum)
ERCC1:ERCC4:RAD51:p-Y104-RAD52:p-RPA:ATR:ATRIP:DNA DSBs with annealed 3' ssDNA overhangs and displaced flaps:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Dictyostelium discoideum)
RAD51:p-Y104-RAD52:p-RPA:ATR:ATRIP:DNA DSBs with annealed 3' ssDNA overhangs and displaced flaps:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Dictyostelium discoideum)
p-Y104-RAD52:p-RPA:ATR:ATRIP:DNA DSBs with annealed 3' ssDNA overhangs and displaced flaps:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Dictyostelium discoideum)
ATR:ATRIP:p-RPA:DNA DSBs with annealed 3' ssDNA overhangs and displaced flaps:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Dictyostelium discoideum)
RAD17:RFC [nucleoplasm] (Dictyostelium discoideum)
RFC2 [nucleoplasm] (Dictyostelium discoideum)
ERCC1:ERCC4:RAD51:p-Y104-RAD52:p-RPA:ATR:ATRIP:SSB-dsDNA with inter-SSA deletion:Flaps:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Dictyostelium discoideum)
RAD51:p-Y104-RAD52:p-RPA:ATR:ATRIP:SSB-dsDNA with inter-SSA deletion:Flaps:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Dictyostelium discoideum)
p-Y104-RAD52:p-RPA:ATR:ATRIP:SSB-dsDNA with inter-SSA deletion:Flaps:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Dictyostelium discoideum)
ATR:ATRIP:p-RPA:SSB-dsDNA with inter-SSA deletion:Flaps:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Dictyostelium discoideum)
RAD17:RFC [nucleoplasm] (Dictyostelium discoideum)
RFC2 [nucleoplasm] (Dictyostelium discoideum)
LIG1 binds SSA sites (Dictyostelium discoideum)
ERCC1:ERCC4:RAD51:p-Y104-RAD52:p-RPA:ATR:ATRIP:SSB-dsDNA with inter-SSA deletion:Flaps:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Dictyostelium discoideum)
RAD51:p-Y104-RAD52:p-RPA:ATR:ATRIP:SSB-dsDNA with inter-SSA deletion:Flaps:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Dictyostelium discoideum)
p-Y104-RAD52:p-RPA:ATR:ATRIP:SSB-dsDNA with inter-SSA deletion:Flaps:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Dictyostelium discoideum)
ATR:ATRIP:p-RPA:SSB-dsDNA with inter-SSA deletion:Flaps:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Dictyostelium discoideum)
RAD17:RFC [nucleoplasm] (Dictyostelium discoideum)
RFC2 [nucleoplasm] (Dictyostelium discoideum)
LIG1:ERCC1:ERCC4:RAD51:p-Y104-RAD52:p-RPA:ATR:ATRIP:SSB-dsDNA with inter-SSA deletion:Flaps:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Dictyostelium discoideum)
ERCC1:ERCC4:RAD51:p-Y104-RAD52:p-RPA:ATR:ATRIP:SSB-dsDNA with inter-SSA deletion:Flaps:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Dictyostelium discoideum)
RAD51:p-Y104-RAD52:p-RPA:ATR:ATRIP:SSB-dsDNA with inter-SSA deletion:Flaps:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Dictyostelium discoideum)
p-Y104-RAD52:p-RPA:ATR:ATRIP:SSB-dsDNA with inter-SSA deletion:Flaps:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Dictyostelium discoideum)
ATR:ATRIP:p-RPA:SSB-dsDNA with inter-SSA deletion:Flaps:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Dictyostelium discoideum)
RAD17:RFC [nucleoplasm] (Dictyostelium discoideum)
RFC2 [nucleoplasm] (Dictyostelium discoideum)
Nucleotide Excision Repair (Dictyostelium discoideum)
Transcription-Coupled Nucleotide Excision Repair (TC-NER) (Dictyostelium discoideum)
Dual incision in TC-NER (Dictyostelium discoideum)
DNA polymerases delta, epsilon or kappa bind the TC-NER site (Dictyostelium discoideum)
RFC Heteropentamer [nucleoplasm] (Dictyostelium discoideum)
RFC2 [nucleoplasm] (Dictyostelium discoideum)
TC-NER incision complex: 5'-incised damaged DNA:trimmed nascent mRNA:(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Dictyostelium discoideum)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Dictyostelium discoideum)
RFC Heteropentamer [nucleoplasm] (Dictyostelium discoideum)
RFC2 [nucleoplasm] (Dictyostelium discoideum)
Gap-filling DNA repair synthesis and ligation in TC-NER (Dictyostelium discoideum)
Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER (Dictyostelium discoideum)
TC-NER post-incision complex:SSB-dsDNA:trimmed nascent mRNA: (PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Dictyostelium discoideum)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Dictyostelium discoideum)
RFC Heteropentamer [nucleoplasm] (Dictyostelium discoideum)
RFC2 [nucleoplasm] (Dictyostelium discoideum)
TC-NER post-incision complex:incised DNA without lesion:trimmed nascent mRNA:PCNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Dictyostelium discoideum)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Dictyostelium discoideum)
RFC Heteropentamer [nucleoplasm] (Dictyostelium discoideum)
RFC2 [nucleoplasm] (Dictyostelium discoideum)
DNA Replication (Dictyostelium discoideum)
Synthesis of DNA (Dictyostelium discoideum)
DNA strand elongation (Dictyostelium discoideum)
Lagging Strand Synthesis (Dictyostelium discoideum)
Polymerase switching (Dictyostelium discoideum)
Loading of PCNA - Sliding Clamp Formation (Dictyostelium discoideum)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Dictyostelium discoideum)
RFC Heteropentamer [nucleoplasm] (Dictyostelium discoideum)
RFC2 [nucleoplasm] (Dictyostelium discoideum)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex:PCNA homotrimer [nucleoplasm] (Dictyostelium discoideum)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Dictyostelium discoideum)
RFC Heteropentamer [nucleoplasm] (Dictyostelium discoideum)
RFC2 [nucleoplasm] (Dictyostelium discoideum)
RFC binding displaces Pol Alpha (Dictyostelium discoideum)
RFC Heteropentamer [nucleoplasm] (Dictyostelium discoideum)
RFC2 [nucleoplasm] (Dictyostelium discoideum)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Dictyostelium discoideum)
RFC Heteropentamer [nucleoplasm] (Dictyostelium discoideum)
RFC2 [nucleoplasm] (Dictyostelium discoideum)
RFC dissociates after sliding clamp formation (Dictyostelium discoideum)
RFC Heteropentamer [nucleoplasm] (Dictyostelium discoideum)
RFC2 [nucleoplasm] (Dictyostelium discoideum)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex:PCNA homotrimer [nucleoplasm] (Dictyostelium discoideum)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Dictyostelium discoideum)
RFC Heteropentamer [nucleoplasm] (Dictyostelium discoideum)
RFC2 [nucleoplasm] (Dictyostelium discoideum)
Leading Strand Synthesis (Dictyostelium discoideum)
Polymerase switching (Dictyostelium discoideum)
Loading of PCNA - Sliding Clamp Formation (Dictyostelium discoideum)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Dictyostelium discoideum)
RFC Heteropentamer [nucleoplasm] (Dictyostelium discoideum)
RFC2 [nucleoplasm] (Dictyostelium discoideum)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex:PCNA homotrimer [nucleoplasm] (Dictyostelium discoideum)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Dictyostelium discoideum)
RFC Heteropentamer [nucleoplasm] (Dictyostelium discoideum)
RFC2 [nucleoplasm] (Dictyostelium discoideum)
RFC binding displaces Pol Alpha (Dictyostelium discoideum)
RFC Heteropentamer [nucleoplasm] (Dictyostelium discoideum)
RFC2 [nucleoplasm] (Dictyostelium discoideum)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Dictyostelium discoideum)
RFC Heteropentamer [nucleoplasm] (Dictyostelium discoideum)
RFC2 [nucleoplasm] (Dictyostelium discoideum)
RFC dissociates after sliding clamp formation (Dictyostelium discoideum)
RFC Heteropentamer [nucleoplasm] (Dictyostelium discoideum)
RFC2 [nucleoplasm] (Dictyostelium discoideum)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex:PCNA homotrimer [nucleoplasm] (Dictyostelium discoideum)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Dictyostelium discoideum)
RFC Heteropentamer [nucleoplasm] (Dictyostelium discoideum)
RFC2 [nucleoplasm] (Dictyostelium discoideum)
External Reference Information
External Reference
UniProt:Q54E21
Reference Genes
BioGPS Gene:8628373
dictyBase:DDB_G0291868
ENSEMBL:DDB_G0291868
KEGG:ddi:DDB_G0291868
Monarch:8628373
NCBI Gene:8628373
UCSC:Q54E21
Reference Transcript
RefSeq:XM_629873.1
Participates
as a component of
CTF18-RFC(7s) complex [nucleoplasm] (Dictyostelium discoideum)
RFC Heteropentamer [nucleoplasm] (Dictyostelium discoideum)
RAD17:RFC [nucleoplasm] (Dictyostelium discoideum)
Inferred From
RFC2 [nucleoplasm]
(Homo sapiens)
Cross References
RefSeq
XP_629875.1
PRO
Q54E21
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