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RFC2 [nucleoplasm]
Stable Identifier
R-HSA-68433
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
RFC40, Activator 1 40 kDa subunit, Replication factor C 40 kDa subunit, A1 40 kDa subunit, RF-C 40 kDa subunit
Locations in the PathwayBrowser
Expand all
Cell Cycle (Homo sapiens)
Cell Cycle Checkpoints (Homo sapiens)
G2/M Checkpoints (Homo sapiens)
Activation of ATR in response to replication stress (Homo sapiens)
Recruitment of Rad17-RFC complex to DNA (Homo sapiens)
RAD17:RFC [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
Rad17-RFC complex bound to DNA [nucleoplasm] (Homo sapiens)
RAD17:RFC [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
Recruitment of the Rad9-Hus1-Rad1 complex to DNA (Homo sapiens)
Rad17-RFC complex bound to DNA [nucleoplasm] (Homo sapiens)
RAD17:RFC [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
Rad9-Hus1-Rad1 bound to DNA [nucleoplasm] (Homo sapiens)
Rad17-RFC complex bound to DNA [nucleoplasm] (Homo sapiens)
RAD17:RFC [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
G2/M DNA damage checkpoint (Homo sapiens)
ATR phosphorylates TP53 (Homo sapiens)
ATR:ATRIP:RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Homo sapiens)
RAD17:RFC [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
Cell Cycle, Mitotic (Homo sapiens)
S Phase (Homo sapiens)
Synthesis of DNA (Homo sapiens)
DNA strand elongation (Homo sapiens)
Lagging Strand Synthesis (Homo sapiens)
Polymerase switching (Homo sapiens)
Loading of PCNA - Sliding Clamp Formation (Homo sapiens)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex:PCNA homotrimer [nucleoplasm] (Homo sapiens)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
RFC binding displaces Pol Alpha (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
RFC dissociates after sliding clamp formation (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex:PCNA homotrimer [nucleoplasm] (Homo sapiens)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
Leading Strand Synthesis (Homo sapiens)
Polymerase switching (Homo sapiens)
Loading of PCNA - Sliding Clamp Formation (Homo sapiens)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex:PCNA homotrimer [nucleoplasm] (Homo sapiens)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
RFC binding displaces Pol Alpha (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
RFC dissociates after sliding clamp formation (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex:PCNA homotrimer [nucleoplasm] (Homo sapiens)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
Chromosome Maintenance (Homo sapiens)
Telomere Maintenance (Homo sapiens)
Extension of Telomeres (Homo sapiens)
Telomere C-strand (Lagging Strand) Synthesis (Homo sapiens)
Polymerase switching on the C-strand of the telomere (Homo sapiens)
Formation of the CTF18-RFC(7s) complex (Homo sapiens)
CTF18-RFC(7s) complex [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
RFC Heteropentamer:RNA primer-DNA primer:G-strand extended telomere end [nucleoplasm] (Homo sapiens)
RFC,(CFT18-RFC) [nucleoplasm] (Homo sapiens)
CTF18-RFC(7s) complex [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
RFC Heteropentamer:RNA primer-DNA primer:G-strand extended telomere end duplex:PCNA homotrimer [nucleoplasm] (Homo sapiens)
RFC Heteropentamer:RNA primer-DNA primer:G-strand extended telomere end [nucleoplasm] (Homo sapiens)
RFC,(CFT18-RFC) [nucleoplasm] (Homo sapiens)
CTF18-RFC(7s) complex [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
RFC binding displaces Pol Alpha on the C-strand of the telomere (Homo sapiens)
RFC Heteropentamer:RNA primer-DNA primer:G-strand extended telomere end [nucleoplasm] (Homo sapiens)
RFC,(CFT18-RFC) [nucleoplasm] (Homo sapiens)
CTF18-RFC(7s) complex [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
RFC,(CFT18-RFC) [nucleoplasm] (Homo sapiens)
CTF18-RFC(7s) complex [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
RFC dissociates after sliding clamp formation on the C-strand of the telomere (Homo sapiens)
RFC Heteropentamer:RNA primer-DNA primer:G-strand extended telomere end duplex:PCNA homotrimer [nucleoplasm] (Homo sapiens)
RFC Heteropentamer:RNA primer-DNA primer:G-strand extended telomere end [nucleoplasm] (Homo sapiens)
RFC,(CFT18-RFC) [nucleoplasm] (Homo sapiens)
CTF18-RFC(7s) complex [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
RFC,(CFT18-RFC) [nucleoplasm] (Homo sapiens)
CTF18-RFC(7s) complex [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
DNA Repair (Homo sapiens)
Base Excision Repair (Homo sapiens)
Resolution of Abasic Sites (AP sites) (Homo sapiens)
Resolution of AP sites via the multiple-nucleotide patch replacement pathway (Homo sapiens)
PCNA-Dependent Long Patch Base Excision Repair (Homo sapiens)
FEN1 bound to PCNA and APEX1 cleaves flap ssDNA (Homo sapiens)
APEX1:FEN1:PCNA:POLD,POLE:RPA:RFC:SSB(3'poly-dNMP-displaced 5'ddRP flap)-dsDNA [nucleoplasm] (Homo sapiens)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
APEX1:PCNA:POLD,POLE:RPA:RFC:SSB(3'poly-dNMP)-dsDNA [nucleoplasm] (Homo sapiens)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
LIG1 binds APEX1 and PCNA at SSB (Homo sapiens)
APEX1:PCNA:POLD,POLE:RPA:RFC:SSB(3'poly-dNMP)-dsDNA [nucleoplasm] (Homo sapiens)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
LIG1:APEX1:PCNA:POLD,POLE:RPA:RFC:SSB:(3'poly-dNMP)-dsDNA [nucleoplasm] (Homo sapiens)
APEX1:PCNA:POLD,POLE:RPA:RFC:SSB(3'poly-dNMP)-dsDNA [nucleoplasm] (Homo sapiens)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
LIG1 bound to APEX1 and PCNA ligates SSB (Homo sapiens)
LIG1:APEX1:PCNA:POLD,POLE:RPA:RFC:SSB:(3'poly-dNMP)-dsDNA [nucleoplasm] (Homo sapiens)
APEX1:PCNA:POLD,POLE:RPA:RFC:SSB(3'poly-dNMP)-dsDNA [nucleoplasm] (Homo sapiens)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
LIG1:APEX1:PCNA:POLD,POLE:RPA:RFC:dsDNA [nucleoplasm] (Homo sapiens)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
LIG1, APEX1 and PCNA:POLD,POLE:RPA:RFC dissociate from repaired DNA (Homo sapiens)
LIG1:APEX1:PCNA:POLD,POLE:RPA:RFC:dsDNA [nucleoplasm] (Homo sapiens)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
PCNA:POLD,POLE:RPA:RFC and FEN1 bind APEX1 (Homo sapiens)
APEX1:FEN1:PCNA:POLD,POLE:RPA:RFC:SSB(3'dNMP-displaced 5'ddRP)-dsDNA [nucleoplasm] (Homo sapiens)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
POLD,POLE-mediated DNA strand displacement synthesis (Homo sapiens)
APEX1:FEN1:PCNA:POLD,POLE:RPA:RFC:SSB(3'dNMP-displaced 5'ddRP)-dsDNA [nucleoplasm] (Homo sapiens)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
APEX1:FEN1:PCNA:POLD,POLE:RPA:RFC:SSB(3'poly-dNMP-displaced 5'ddRP flap)-dsDNA [nucleoplasm] (Homo sapiens)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
DNA Damage Bypass (Homo sapiens)
Recognition of DNA damage by PCNA-containing replication complex (Homo sapiens)
PCNA-containing replication complex binds damaged dsDNA (Homo sapiens)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
PCNA:POLD,POLE:RPA:RFC:Damaged DNA Template [nucleoplasm] (Homo sapiens)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
RAD18:UBE2B or RBX1:CUL4:DDB1:DTL monoubiquitinates PCNA (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:Damaged DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
RAD18:UBE2B,RBX1:CUL4:DDB1:DTL:PCNA:POLD,POLE:RPA:RFC:Damaged DNA Template [nucleoplasm] (Homo sapiens)
PCNA:POLD,POLE:RPA:RFC:Damaged DNA Template [nucleoplasm] (Homo sapiens)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
RAD18:UBE2B or RBX1:CUL4:DDB1:DTL ubiquitin ligase complex binds PCNA:POLD,POLE:RPA:RFC associated with damaged dsDNA (Homo sapiens)
PCNA:POLD,POLE:RPA:RFC:Damaged DNA Template [nucleoplasm] (Homo sapiens)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
RAD18:UBE2B,RBX1:CUL4:DDB1:DTL:PCNA:POLD,POLE:RPA:RFC:Damaged DNA Template [nucleoplasm] (Homo sapiens)
PCNA:POLD,POLE:RPA:RFC:Damaged DNA Template [nucleoplasm] (Homo sapiens)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
USP1:WDR48 binds monoUb:K164-PCNA (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:Damaged DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:USP1:WDR48:Damaged DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:Damaged DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
USP1:WDR48 deubiquitinates monoUb:K164-PCNA (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:USP1:WDR48:Damaged DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:Damaged DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
PCNA:RPA:RFC:Damaged DNA Template [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template (Homo sapiens)
Termination of translesion DNA synthesis (Homo sapiens)
POLD,POLE binds deISGylated PCNA after TLS (Homo sapiens)
PCNA:POLD,POLE:RPA:RFC:TLS-DNA Template [nucleoplasm] (Homo sapiens)
PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
POLD,POLE complete replication of damaged DNA after TLS (Homo sapiens)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
PCNA:POLD,POLE:RPA:RFC:TLS-DNA Template [nucleoplasm] (Homo sapiens)
PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
TRIM25 binds monoUb:164-PCNA (Homo sapiens)
DNA polymerase Y:MonoUb:K164-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
UBE2L6:TRIM25:DNA polymerase Y:MonoUb:K164-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Homo sapiens)
DNA polymerase Y:MonoUb:K164-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
UBE2L6:TRIM25 ISGylates monoUb:K164-PCNA (Homo sapiens)
DNA polymerase Y:MonoUb:K164,ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
UBE2L6:TRIM25:DNA polymerase Y:MonoUb:K164-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Homo sapiens)
DNA polymerase Y:MonoUb:K164-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
USP10 binds monoUb:K164,ISG:K164,ISG:K168-PCNA (Homo sapiens)
DNA polymerase Y:MonoUb:K164,ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
USP10:DNA polymerase Y:MonoUb:K164,ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Homo sapiens)
DNA polymerase Y:MonoUb:K164,ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
USP10 deubiquitinates monoUb:K164,ISG:K164,ISG:K168-PCNA (Homo sapiens)
ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
USP10:DNA polymerase Y:MonoUb:K164,ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Homo sapiens)
DNA polymerase Y:MonoUb:K164,ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
USP43 binds ISG:K164,ISG:K168-PCNA (Homo sapiens)
ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
USP43:ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Homo sapiens)
ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
USP43 deISGylates ISG:K164,ISG:K168-PCNA (Homo sapiens)
PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
USP43:ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Homo sapiens)
ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
Translesion Synthesis by POLH (Homo sapiens)
Elongation by POLH (Homo sapiens)
POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA)-DNA Template [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
Insertion of correct bases opposite the lesion by POLH (Homo sapiens)
POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA)-DNA Template [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
POLH:MonoUb:K164-PCNA:RPA:RFC:TT-CPD-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:TT-CPD-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
POLH binds monoUb:K164-PCNA at damaged TT-CPD-DNA template (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:TT-CPD-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
POLH:MonoUb:K164-PCNA:RPA:RFC:TT-CPD-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:TT-CPD-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
SPRTN binds monoUb:K164-PCNA associated with POLH (Homo sapiens)
POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
SPRTN:POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Homo sapiens)
POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
SPRTN recruits VCP to monoUb:K164-PCNA associated with POLH (Homo sapiens)
NPLOC4:UFD1L:VCP:SPRTN:POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Homo sapiens)
SPRTN:POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Homo sapiens)
POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
SPRTN:POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Homo sapiens)
POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
SPRTN:VCP-mediated release of POLH from monoUb:K164-PCNA (Homo sapiens)
NPLOC4:UFD1L:VCP:SPRTN:POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Homo sapiens)
SPRTN:POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Homo sapiens)
POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
NPLOC4:UFD1L:VPC:SPRTN:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-Template DNA [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
Translesion synthesis by POLI (Homo sapiens)
POLI incorporates dNMP opposite to damaged DNA base (Homo sapiens)
POLI:REV1:POLZ:MonoUb:K164-PCNA:RPA:RFC:(EtAD:T)-DNA Template,(Gamma-HOPdG:C)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:(EtAD:T)-DNA Template,(Gamma-HOPdG:C)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
POLI:REV1:POLZ:MonoUb:K164-PCNA:RPA:RFC:EtAD-DNA Template,Gamma-HOPdG-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:EtAD-DNA Template,Gamma-HOPdG-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
POLI simultaneously binds REV1 and monoUb:K164-PCNA at damaged DNA (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:EtAD-DNA Template,Gamma-HOPdG-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
POLI:REV1:POLZ:MonoUb:K164-PCNA:RPA:RFC:EtAD-DNA Template,Gamma-HOPdG-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:EtAD-DNA Template,Gamma-HOPdG-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
POLZ elongates POLI-incorporated dNMP (Homo sapiens)
POLI:MonoUb:K164-PCNA:RPA:RFC:(EtAD:T-mispaireddNMPs)-DNA Template,(Gamma-HOPdG:C-mispaireddNMPs)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:(EtAD:T-mispaireddNMPs)-DNA Template,(Gamma-HOPdG:C-mispaireddNMPs)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
POLI:REV1:POLZ:MonoUb:K164-PCNA:RPA:RFC:(EtAD:T)-DNA Template,(Gamma-HOPdG:C)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:(EtAD:T)-DNA Template,(Gamma-HOPdG:C)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
Translesion synthesis by POLK (Homo sapiens)
POLK and POLZ cooperate in elongation of mispaired primer termini (Homo sapiens)
POLK:MonoUb:K164-PCNA:RPA:RFC:(Tg:A-mispaireddNMPs)-DNA Template,(OGUA:A-mispaireddNMPs)-DNA Template,(BPDE-G:C-mispaireddNMPs)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:(Tg:A-mispaireddNMPs)-DNA Template,(OGUA:A-mispaireddNMPs)-DNA Template,(BPDE-G:C-mispaireddNMPs)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
POLK:REV1:POLZ:MonoUb:K164-PCNA:RPA:RFC:(Tg:A)-DNA Template,(OGUA:A)-DNA Template,(BPDE-G:C)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:(Tg:A)-DNA Template,(OGUA:A)-DNA Template,(BPDE-G:C)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
POLK forms a quaternary complex with REV1 and POLZ on damaged DNA template (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:Tg-DNA Template,OGUA-DNA Template,BPDE-G-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
POLK:REV1:POLZ:MonoUb:K164-PCNA:RPA:RFC:Tg-DNA Template,OGUA-DNA Template,BPDE-G-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:Tg-DNA Template,OGUA-DNA Template,BPDE-G-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
POLK incorporates dNMP opposite to damaged DNA base (Homo sapiens)
POLK:REV1:POLZ:MonoUb:K164-PCNA:RPA:RFC:(Tg:A)-DNA Template,(OGUA:A)-DNA Template,(BPDE-G:C)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:(Tg:A)-DNA Template,(OGUA:A)-DNA Template,(BPDE-G:C)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
POLK:REV1:POLZ:MonoUb:K164-PCNA:RPA:RFC:Tg-DNA Template,OGUA-DNA Template,BPDE-G-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:Tg-DNA Template,OGUA-DNA Template,BPDE-G-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
Translesion synthesis by REV1 (Homo sapiens)
POLZ extends translesion synthesis (Homo sapiens)
POLZ:REV1:MonoUb:K164-PCNA:RPA:RFC:(AP:Cyt)-DNA Template [nucleoplasm] (Homo sapiens)
REV1:MonoUb:K164-PCNA:RPA:RFC:(AP:Cyt)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:(AP:Cyt)-dsDNA [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
REV1:MonoUb:K164-PCNA:RPA:RFC:(AP:Cyt-mispairedPolydNMP)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
REV1 binds AP-dsDNA (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:AP-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
REV1:MonoUb:K164-PCNA:RPA:RFC:AP-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:AP-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
REV1 inserts dCMP opposite to AP sites in DNA (Homo sapiens)
REV1:MonoUb:K164-PCNA:RPA:RFC:(AP:Cyt)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:(AP:Cyt)-dsDNA [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
REV1:MonoUb:K164-PCNA:RPA:RFC:AP-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:AP-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
REV1 recruits POLZ to (AP:Cyt)-DNA Template (Homo sapiens)
POLZ:REV1:MonoUb:K164-PCNA:RPA:RFC:(AP:Cyt)-DNA Template [nucleoplasm] (Homo sapiens)
REV1:MonoUb:K164-PCNA:RPA:RFC:(AP:Cyt)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:(AP:Cyt)-dsDNA [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
REV1:MonoUb:K164-PCNA:RPA:RFC:(AP:Cyt)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:(AP:Cyt)-dsDNA [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
DNA Double-Strand Break Repair (Homo sapiens)
Homology Directed Repair (Homo sapiens)
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) (Homo sapiens)
HDR through Homologous Recombination (HRR) (Homo sapiens)
D-loop extension by DNA polymerases (Homo sapiens)
PCNA:POLD,POLE,POLH,POLK:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:POLH,POLK [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
Homologous DNA Pairing and Strand Exchange (Homo sapiens)
Presynaptic phase of homologous DNA pairing and strand exchange (Homo sapiens)
RAD51 binds BRCA2 at resected DNA DSBs (Homo sapiens)
ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Homo sapiens)
RAD17:RFC [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
RAD17:RFC [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
HDR through Single Strand Annealing (SSA) (Homo sapiens)
Association of RAD51 with RAD52:DNA double-strand break ends (Homo sapiens)
RAD51:p-Y104-RAD52:p-RPA:ATR:ATRIP:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Homo sapiens)
p-Y104-RAD52:p-RPA:ATR:ATRIP:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Homo sapiens)
ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Homo sapiens)
RAD17:RFC [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
p-Y104-RAD52:p-RPA:ATR:ATRIP:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Homo sapiens)
ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Homo sapiens)
RAD17:RFC [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
Association of RAD52 with the RPA complex at resected DNA DSBs (Homo sapiens)
ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Homo sapiens)
RAD17:RFC [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
p-Y104-RAD52:p-RPA:ATR:ATRIP:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Homo sapiens)
ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Homo sapiens)
RAD17:RFC [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
ERCC1:XPF cleaves flaps generated by SSA (Homo sapiens)
RAD17:RFC [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
RAD51:p-Y104-RAD52:p-RPA:ATR:ATRIP:DNA DSBs with annealed 3' ssDNA overhangs and displaced flaps:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Homo sapiens)
p-Y104-RAD52:p-RPA:ATR:ATRIP:DNA DSBs with annealed 3' ssDNA overhangs and displaced flaps:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Homo sapiens)
ATR:ATRIP:p-RPA:DNA DSBs with annealed 3' ssDNA overhangs and displaced flaps:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Homo sapiens)
RAD17:RFC [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
RAD52 promotes single strand annealing at resected DNA DSBs (Homo sapiens)
RAD51:p-Y104-RAD52:p-RPA:ATR:ATRIP:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Homo sapiens)
p-Y104-RAD52:p-RPA:ATR:ATRIP:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Homo sapiens)
ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Homo sapiens)
RAD17:RFC [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
RAD51:p-Y104-RAD52:p-RPA:ATR:ATRIP:DNA DSBs with annealed 3' ssDNA overhangs and displaced flaps:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Homo sapiens)
p-Y104-RAD52:p-RPA:ATR:ATRIP:DNA DSBs with annealed 3' ssDNA overhangs and displaced flaps:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Homo sapiens)
ATR:ATRIP:p-RPA:DNA DSBs with annealed 3' ssDNA overhangs and displaced flaps:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Homo sapiens)
RAD17:RFC [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
Processing of DNA double-strand break ends (Homo sapiens)
ATR activation at DNA DSBs (Homo sapiens)
ATR:ATRIP:RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Homo sapiens)
RAD17:RFC [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
RAD17:RFC [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
ATR phosphorylates RPA2 (Homo sapiens)
ATR:ATRIP:RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Homo sapiens)
RAD17:RFC [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Homo sapiens)
RAD17:RFC [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
Activation of CHEK1 at resected DNA DSBs (Homo sapiens)
ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Homo sapiens)
RAD17:RFC [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1:TIMELESS:TIPIN:p-T916,S945-CLSPN:CHEK1 [nucleoplasm] (Homo sapiens)
RAD17:RFC [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
CHEK1 is recruited to resected DNA DSBs (Homo sapiens)
ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Homo sapiens)
RAD17:RFC [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1:TIMELESS:TIPIN:p-T916,S945-CLSPN:CHEK1 [nucleoplasm] (Homo sapiens)
RAD17:RFC [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
Nucleotide Excision Repair (Homo sapiens)
Global Genome Nucleotide Excision Repair (GG-NER) (Homo sapiens)
Dual Incision in GG-NER (Homo sapiens)
3'-incision of DNA by ERCC5 (XPG) in GG-NER (Homo sapiens)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC:Incised DNA without lesion [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
GG-NER incision complex:5'-incised damaged DNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
DNA polymerases delta, epsilon or kappa bind the GG-NER site (Homo sapiens)
GG-NER incision complex:5'-incised damaged DNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
Gap-filling DNA repair synthesis and ligation in GG-NER (Homo sapiens)
Ligation of newly synthesized repair patch to incised DNA in GG-NER (Homo sapiens)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC:SSB-dsDNA [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in GG-NER (Homo sapiens)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC:Incised DNA without lesion [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC:SSB-dsDNA [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
Transcription-Coupled Nucleotide Excision Repair (TC-NER) (Homo sapiens)
Dual incision in TC-NER (Homo sapiens)
3' incision by ERCC5 (XPG) in TC-NER (Homo sapiens)
TC-NER incision complex: 5'-incised damaged DNA:trimmed nascent mRNA:(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
TC-NER post-incision complex:incised DNA without lesion:trimmed nascent mRNA:PCNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
DNA polymerases delta, epsilon or kappa bind the TC-NER site (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
TC-NER incision complex: 5'-incised damaged DNA:trimmed nascent mRNA:(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
Gap-filling DNA repair synthesis and ligation in TC-NER (Homo sapiens)
Ligation of newly synthesized repair patch to incised DNA in TC-NER (Homo sapiens)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
TC-NER post-incision complex:SSB-dsDNA:trimmed nascent mRNA: (PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER (Homo sapiens)
TC-NER post-incision complex:SSB-dsDNA:trimmed nascent mRNA: (PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
TC-NER post-incision complex:incised DNA without lesion:trimmed nascent mRNA:PCNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
DNA Replication (Homo sapiens)
Synthesis of DNA (Homo sapiens)
DNA strand elongation (Homo sapiens)
Lagging Strand Synthesis (Homo sapiens)
Polymerase switching (Homo sapiens)
Loading of PCNA - Sliding Clamp Formation (Homo sapiens)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex:PCNA homotrimer [nucleoplasm] (Homo sapiens)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
RFC binding displaces Pol Alpha (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
RFC dissociates after sliding clamp formation (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex:PCNA homotrimer [nucleoplasm] (Homo sapiens)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
Leading Strand Synthesis (Homo sapiens)
Polymerase switching (Homo sapiens)
Loading of PCNA - Sliding Clamp Formation (Homo sapiens)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex:PCNA homotrimer [nucleoplasm] (Homo sapiens)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
RFC binding displaces Pol Alpha (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
RFC dissociates after sliding clamp formation (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex:PCNA homotrimer [nucleoplasm] (Homo sapiens)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
Disease (Homo sapiens)
Diseases of DNA repair (Homo sapiens)
Diseases of DNA Double-Strand Break Repair (Homo sapiens)
Defective homologous recombination repair (HRR) due to BRCA2 loss of function (Homo sapiens)
Impaired BRCA2 binding to RAD51 (Homo sapiens)
BRCA2 mutants with BRC defects or a defect in the C-terminal RAD51 binding site do not bind RAD51 (Homo sapiens)
ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Homo sapiens)
RAD17:RFC [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
Gene expression (Transcription) (Homo sapiens)
RNA Polymerase II Transcription (Homo sapiens)
Generic Transcription Pathway (Homo sapiens)
Transcriptional Regulation by TP53 (Homo sapiens)
Regulation of TP53 Activity (Homo sapiens)
Regulation of TP53 Activity through Phosphorylation (Homo sapiens)
ATR phosphorylates TP53 (Homo sapiens)
ATR:ATRIP:RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Homo sapiens)
RAD17:RFC [nucleoplasm] (Homo sapiens)
RFC2 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:P35250 RFC2
Gene Names
RFC2
Chain
chain:1-354
Reference Genes
BioGPS Gene:5982 RFC2
COSMIC (genes):RFC2 RFC2
CTD Gene:5982 RFC2
dbSNP Gene:5982 RFC2
ENSEMBL:ENSG00000049541 RFC2
ENSEMBL_homo_sapiens_GENE:ENSG00000049541.11 RFC2
HGNC:9970 RFC2
KEGG Gene (Homo sapiens):5982 RFC2
Monarch:5982 RFC2
NCBI Gene:5982 RFC2
OMIM:600404 RFC2
UCSC:P35250 RFC2
Reference Transcript
RefSeq:NM_001278792.1 RFC2
RefSeq:NM_002914.4 RFC2
RefSeq:NM_001278791.1 RFC2
RefSeq:NM_001278793.1 RFC2
RefSeq:NM_181471.2 RFC2
Other Identifiers
1053_3p_at
1053_PM_at
1053_at
11735167_x_at
17058617
203696_3p_s_at
203696_PM_s_at
203696_s_at
3056415
3056416
3056417
3056420
3056422
3056423
3056425
3056427
3056428
3056429
3056431
3056433
3056435
3056436
5982
8140151
A_23_P93823
GE79580
GO:0000166
GO:0003677
GO:0003689
GO:0003824
GO:0005515
GO:0005524
GO:0005634
GO:0005654
GO:0005663
GO:0005694
GO:0006260
GO:0006261
GO:0006281
GO:0016787
GO:0016887
GO:0017116
GO:0019899
GO:0031390
GO:0032508
GO:0043226
GO:0140097
GO:0140657
GO:1900264
HMNXSV003035772
HMNXSV003053080
ILMN_1655733
ILMN_1732336
M87338_at
PH_hs_0008339
TC07001509.hg
Participates
as an input of
Formation of the CTF18-RFC(7s) complex (Homo sapiens)
as a component of
CTF18-RFC(7s) complex [nucleoplasm] (Homo sapiens)
RFC Heteropentamer [nucleoplasm] (Homo sapiens)
RAD17:RFC [nucleoplasm] (Homo sapiens)
Inferred To
Ghost homologue of RFC2 [nucleoplasm]
(Danio rerio)
rfc-2 [nucleoplasm]
(Caenorhabditis elegans)
rfc2 [nucleoplasm]
(Xenopus tropicalis)
RFC2 [nucleoplasm]
(Bos taurus)
RFC2 [nucleoplasm]
(Canis familiaris)
RFC2 [nucleoplasm]
(Dictyostelium discoideum)
RFC2 [nucleoplasm]
(Drosophila melanogaster)
RFC2 [nucleoplasm]
(Gallus gallus)
RFC2 [nucleoplasm]
(Mus musculus)
RFC2 [nucleoplasm]
(Plasmodium falciparum)
RFC2 [nucleoplasm]
(Rattus norvegicus)
RFC2 [nucleoplasm]
(Saccharomyces cerevisiae)
RFC2 [nucleoplasm]
(Schizosaccharomyces pombe)
RFC2 [nucleoplasm]
(Sus scrofa)
Cross References
RefSeq
NP_001265721.1
,
NP_001265722.1
,
NP_002905.2
,
NP_001265720.1
,
NP_852136.1
OpenTargets
ENSG00000049541
HPA
ENSG00000049541-RFC2
GeneCards
P35250
Ensembl
ENST00000352131
,
ENST00000055077
,
ENSP00000275627
,
ENSP00000055077
,
ENSG00000049541
PRO
P35250
Pharos - Targets
P35250
Orphanet
15201
PDB
6VVO
,
7Z6H
Interactors (9)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P35249 RFC4
1
RFC4 [nucleoplasm]
(R-HSA-68429)
0.757
11
UniProt:O75943 RAD17
1
RAD17 [nucleoplasm]
(R-HSA-3008665)
0.643
3
UniProt:P35251 RFC1
1
RFC1 [nucleoplasm]
(R-HSA-68435)
0.641
4
UniProt:P40937 RFC5
1
RFC5 [nucleoplasm]
(R-HSA-68427)
0.564
3
UniProt:P12004 PCNA
5
monoSUMO1-K164,K254,K-PCNA [nucleoplasm]
(R-HSA-4615861)
K63polyUb-K164-PCNA [nucleoplasm]
(R-HSA-8943000)
ISG-K164,ISG-K168-PCNA [nucleoplasm]
(R-HSA-5653768)
MonoUb-K164-PCNA [nucleoplasm]
(R-HSA-5651986)
PCNA [nucleoplasm]
(R-HSA-68439)
0.527
2
UniProt:P10644 PRKAR1A
4
PRKAR1A(1-183)-p-7Y-ALK(1058-1620) fusion [cytosol]
(R-HSA-9713476)
PRKAR1A(1-183)-ALK(1058-1620) fusion [cytosol]
(R-HSA-9713471)
PRKAR1A [ciliary base]
(R-HSA-5610408)
PRKAR1A [cytosol]
(R-HSA-57836)
0.524
7
UniProt:P06463 VE6
0.488
2
UniProt:P13569 CFTR
17
PolyUb-CFTR [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869104)
PolyUb-CFTR [plasma membrane]
(R-HSA-8867595)
CFTR [lysosomal membrane]
(R-HSA-5627279)
CFTR [Golgi-associated vesicle membrane]
(R-HSA-5627079)
CFTR [endosome membrane]
(R-HSA-6782965)
PolyUb-CFTR [endosome membrane]
(R-HSA-6782976)
CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866834)
ub-CFTR F508del [cytosol]
(R-HSA-8866838)
ub-CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866842)
CFTR G542* [plasma membrane]
(R-HSA-5678986)
CFTR G551D [plasma membrane]
(R-HSA-5678977)
CFTR W1282* [plasma membrane]
(R-HSA-5678976)
CFTR F508del [plasma membrane]
(R-HSA-5678978)
CFTR N1303K [plasma membrane]
(R-HSA-5678983)
CFTR [plasma membrane]
(R-HSA-383188)
CFTR [endoplasmic reticulum membrane]
(R-HSA-8866837)
misfolded CFTR [endoplasmic reticulum membrane]
(R-HSA-8868730)
0.483
9
UniProt:P06748 NPM1
11
monoSUMO1-K263-NPM1 [nucleoplasm]
(R-HSA-4086039)
polySUMO2,3-K263-NPM1 [nucleoplasm]
(R-HSA-4086056)
NPM1(1-117)-p-7Y-ALK(1058-1620) fusion [nucleoplasm]
(R-HSA-9725010)
NPM1(1-117)-p-7Y-ALK(1068-1620) fusion [cytosol]
(R-HSA-9730703)
NPM1(1-117)-ALK(1068-1620) fusion [cytosol]
(R-HSA-9730697)
NPM1(1-117)-p-7Y-ALK(1058-1620) fusion [cytosol]
(R-HSA-9699861)
NPM1(1-117)-ALK(1058-1620) fusion [cytosol]
(R-HSA-9699834)
NPM1 [granular component]
(R-HSA-9017702)
NPM1 [nucleoplasm]
(R-HSA-606320)
NPM1 [cytosol]
(R-HSA-3008211)
p-S4-NPM1 [cytosol]
(R-HSA-6801679)
0.483
2
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