Reactome | PDE5A [cytosol]

PDE5A [cytosol]

Stable Identifier

R-DDI-418508

Type

Protein [EntityWithAccessionedSequence]

Species

Dictyostelium discoideum

Compartment

cytosol

Synonyms

B0G0Y8

Locations in the PathwayBrowser

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Hemostasis (Dictyostelium discoideum)

- Platelet homeostasis (Dictyostelium discoideum)
  - Nitric oxide stimulates guanylate cyclase (Dictyostelium discoideum)
    - cGMP effects (Dictyostelium discoideum)
      - cGMP is degraded by PDEs (Dictyostelium discoideum)
        
        cGMP phosphodiesterases [cytosol] (Dictyostelium discoideum)
        
        Homologues of PDE5A [cytosol] (Dictyostelium discoideum)
        
        PDE5A [cytosol] (Dictyostelium discoideum)

Signal Transduction (Dictyostelium discoideum)

- Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Dictyostelium discoideum)
  - Signaling by Rho GTPases (Dictyostelium discoideum)
    - RHO GTPase cycle (Dictyostelium discoideum)
      - RHOBTB GTPase Cycle (Dictyostelium discoideum)
        
        RHOBTB1 GTPase cycle (Dictyostelium discoideum)
        
        RHOBTB1 binds interacting proteins at the endosome membrane (Dictyostelium discoideum)
        
        RHOBTB1 interacting proteins [cytosol] (Dictyostelium discoideum)
        
        Homologues of PDE5A [cytosol] (Dictyostelium discoideum)
        
        PDE5A [cytosol] (Dictyostelium discoideum)
        
        RHOBTB1:GTP:RHOBTB1 interacting proteins [endosome membrane] (Dictyostelium discoideum)
        
        RHOBTB1 interacting proteins [cytosol] (Dictyostelium discoideum)
        
        Homologues of PDE5A [cytosol] (Dictyostelium discoideum)
        
        PDE5A [cytosol] (Dictyostelium discoideum)

External Reference Information

External Reference

UniProt:B0G0Y8

Reference Genes

BioGPS Gene:8616668

dictyBase:DDB_G0268634

ENSEMBL:DDB_G0268634

KEGG:ddi:DDB_G0268634

Monarch:8616668

NCBI Gene:8616668

UCSC:B0G0Y8

Reference Transcript

RefSeq:XM_001732899.1

Participates

as a member of

Homologues of PDE5A [cytosol] (Dictyostelium discoideum)

Other forms of this molecule

PDE6B(1-851) [photoreceptor disc membrane]

PDE6A(2-860) [photoreceptor disc membrane]

PDE8A [cytosol]

PDE8B [cytosol]

PDE7A [cytosol]

PDE7B [cytosol]

PDE10A [cytosol]

PDE11A [cytosol]

PDE2A [cytosol]

PDE3A [cytosol]

PDE3B [cytosol]

phospho-p-S295-PDE3B [cytosol]

PDE6A [plasma membrane]

PDE6B [plasma membrane]

Inferred From

PDE5A [cytosol] (Homo sapiens)

Cross References

RefSeq

XP_001732951.1

PRO

B0G0Y8

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