Reactome | psmA2 [nucleoplasm]

psmA2 [nucleoplasm]

Stable Identifier

R-DDI-174345

Type

Protein [EntityWithAccessionedSequence]

Species

Dictyostelium discoideum

Compartment

nucleoplasm

Synonyms

PSMA2, Q54DM7

Locations in the PathwayBrowser

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Cell Cycle (Dictyostelium discoideum)

- Cell Cycle Checkpoints (Dictyostelium discoideum)
  - G1/S DNA Damage Checkpoints (Dictyostelium discoideum)
    - p53-Independent G1/S DNA Damage Checkpoint (Dictyostelium discoideum)
      - Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A (Dictyostelium discoideum)
        
        Proteolytic degradation of ubiquitinated-Cdc25A (Dictyostelium discoideum)
        
        26S proteasome [nucleoplasm] (Dictyostelium discoideum)
        
        20S core particle [nucleoplasm] (Dictyostelium discoideum)
        
        20S CP outer ring [nucleoplasm] (Dictyostelium discoideum)
        
        psmA2 [nucleoplasm] (Dictyostelium discoideum)
- Cell Cycle, Mitotic (Dictyostelium discoideum)
  - Mitotic G1 phase and G1/S transition (Dictyostelium discoideum)
    - G1/S Transition (Dictyostelium discoideum)
      - Cyclin E associated events during G1/S transition (Dictyostelium discoideum)
        
        SCF(Skp2)-mediated degradation of p27/p21 (Dictyostelium discoideum)
        
        Degradation of ubiquitinated p27/p21 by the 26S proteasome (Dictyostelium discoideum)
        
        26S proteasome [nucleoplasm] (Dictyostelium discoideum)
        
        20S core particle [nucleoplasm] (Dictyostelium discoideum)
        
        20S CP outer ring [nucleoplasm] (Dictyostelium discoideum)
        
        psmA2 [nucleoplasm] (Dictyostelium discoideum)
  - Regulation of mitotic cell cycle (Dictyostelium discoideum)
    - APC/C-mediated degradation of cell cycle proteins (Dictyostelium discoideum)
      - APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 (Dictyostelium discoideum)
        
        APC/C:Cdh1-mediated degradation of Skp2 (Dictyostelium discoideum)
        
        26S proteasome [nucleoplasm] (Dictyostelium discoideum)
        
        20S core particle [nucleoplasm] (Dictyostelium discoideum)
        
        20S CP outer ring [nucleoplasm] (Dictyostelium discoideum)
        
        psmA2 [nucleoplasm] (Dictyostelium discoideum)
      - Autodegradation of Cdh1 by Cdh1:APC/C (Dictyostelium discoideum)
        
        Degradation of multiubiquitinated Cdh1 (Dictyostelium discoideum)
        
        26S proteasome [nucleoplasm] (Dictyostelium discoideum)
        
        20S core particle [nucleoplasm] (Dictyostelium discoideum)
        
        20S CP outer ring [nucleoplasm] (Dictyostelium discoideum)
        
        psmA2 [nucleoplasm] (Dictyostelium discoideum)
  - S Phase (Dictyostelium discoideum)
    - Cyclin A:Cdk2-associated events at S phase entry (Dictyostelium discoideum)
      - SCF(Skp2)-mediated degradation of p27/p21 (Dictyostelium discoideum)
        
        Degradation of ubiquitinated p27/p21 by the 26S proteasome (Dictyostelium discoideum)
        
        26S proteasome [nucleoplasm] (Dictyostelium discoideum)
        
        20S core particle [nucleoplasm] (Dictyostelium discoideum)
        
        20S CP outer ring [nucleoplasm] (Dictyostelium discoideum)
        
        psmA2 [nucleoplasm] (Dictyostelium discoideum)

External Reference Information

External Reference

UniProt:Q54DM7

Gene Names

psmA2

Reference Genes

BioGPS Gene:8628525 psmA2

dictyBase:DDB_G0292122

ENSEMBL:DDB_G0292122

KEGG:ddi:DDB_G0292122 psmA2

Monarch:8628525 psmA2

NCBI Gene:8628525 psmA2

UCSC:Q54DM7 psmA2

Reference Transcript

RefSeq:XM_629843.1 psmA2

Participates

as a component of

20S CP outer ring [nucleoplasm] (Dictyostelium discoideum)

Other forms of this molecule

psmA2 [secretory granule lumen]

psmA2 [extracellular region]

psmA2 [ficolin-1-rich granule lumen]

psmA2 [cytosol]

Inferred From

PSMA2 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

XP_629845.1

PRO

Q54DM7